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https://www.readbyqxmd.com/read/29330597/inpatient-treatment-of-patients-with-idiopathic-sudden-sensorineural-hearing-loss-a-population-based-healthcare-research-study
#1
Anne Heuschkel, Katharina Geißler, Daniel Boeger, Jens Buentzel, Dirk Esser, Kerstin Hoffmann, Peter Jecker, Andreas Mueller, Gerald Radtke, Orlando Guntinas-Lichius
PURPOSE: The aim was to determine inpatient treatment rates of idiopathic sudden sensorineural hearing loss (ISSNHL) with focus on diagnostics, treatment, and outcome. METHODS: A retrospective population-based study in the federal state Thuringia in 2011 and 2012 was performed on all 490 inpatients (51% females, median age: 60 years) treated for ISSNHL (Median duration: 7 days). The association between analyzed parameters and the probability of recovery was tested using univariable and multivariable statistics...
January 12, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29328115/digital-holography-and-3d-imaging-introduction-to-the-joint-feature-issue-in-applied-optics-and-journal-of-the-optical-society-of-america-a
#2
Hoonjong Kang, Byoungho Lee, Tomasz Kozacki, Pascal Picart, Guohai Situ
The OSA Topical Meeting on Digital Holography and 3D Imaging (DH) was held 29 May to 1 June 2017 in Jeju Island, South Korea. Feature issues based on the DH meeting series have been released by Applied Optics (AO) since 2007. This year, AO and the Journal of the Optical Society of America A (JOSA A) jointly decided to have one such feature issue in each journal. This feature issue includes 33 papers in AO and 9 in JOSA A and covers a large range of topics, reflecting the rapidly expanding techniques and applications of digital holography and 3D imaging...
January 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29328075/digital-holography-and-3d-imaging-introduction-to-the-joint-feature-issue-in-applied-optics-and-journal-of-the-optical-society-of-america-a
#3
Hoonjong Kang, Byoungho Lee, Tomasz Kozacki, Pascal Picart, Guohai Situ
The OSA Topical Meeting on Digital Holography and 3D Imaging (DH) was held 29 May to 1 June 2017 on Jeju Island, South Korea. Feature issues based on the DH meeting series have been released by Applied Optics (AO) since 2007. This year, AO and the Journal of the Optical Society of America A (JOSA A) jointly decided to have one such feature issue in each journal. This feature issue includes 33 papers in AO and 9 in JOSA A and covers a large range of topics, reflecting the rapidly expanding techniques and applications of digital holography and 3D imaging...
January 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29323294/terminal-pleistocene-alaskan-genome-reveals-first-founding-population-of-native-americans
#4
J Víctor Moreno-Mayar, Ben A Potter, Lasse Vinner, Matthias Steinrücken, Simon Rasmussen, Jonathan Terhorst, John A Kamm, Anders Albrechtsen, Anna-Sapfo Malaspinas, Martin Sikora, Joshua D Reuther, Joel D Irish, Ripan S Malhi, Ludovic Orlando, Yun S Song, Rasmus Nielsen, David J Meltzer, Eske Willerslev
Despite broad agreement that the Americas were initially populated via Beringia, the land bridge that connected far northeast Asia with northwestern North America during the Pleistocene epoch, when and how the peopling of the Americas occurred remains unresolved. Analyses of human remains from Late Pleistocene Alaska are important to resolving the timing and dispersal of these populations. The remains of two infants were recovered at Upward Sun River (USR), and have been dated to around 11.5 thousand years ago (ka)...
January 11, 2018: Nature
https://www.readbyqxmd.com/read/29321534/mitochondrial-network-complexity-emerges-from-fission-fusion-dynamics
#5
Nahuel Zamponi, Emiliano Zamponi, Sergio A Cannas, Orlando V Billoni, Pablo R Helguera, Dante R Chialvo
Mitochondrial networks exhibit a variety of complex behaviors, including coordinated cell-wide oscillations of energy states as well as a phase transition (depolarization) in response to oxidative stress. Since functional and structural properties are often interwinded, here we characterized the structure of mitochondrial networks in mouse embryonic fibroblasts using network tools and percolation theory. Subsequently we perturbed the system either by promoting the fusion of mitochondrial segments or by inducing mitochondrial fission...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29320878/exercise-training-for-improving-outcomes-post-burns-a-systematic-review-and-meta-analysis
#6
Orlando Flores, Zephanie Tyack, Kellie Stockton, Robert Ware, Jennifer D Paratz
OBJECTIVES: To determine the effectiveness of different modalities of exercise and to evaluate the safety of exercise-based interventions post-burns. DATA SOURCES: Six databases were searched from inception to October 2017 using "burn," "exercise" and synonyms as keywords. Relevant authors, key journals and reference lists of included studies were hand-searched. REVIEW METHODS: Articles reporting on exercise interventions in patients post-burn and considering physical, physiological or psychological outcomes were considered...
January 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29318751/subgroup-analysis-of-east-asian-patients-in-regard-a-phase-iii-trial-of-ramucirumab-and-best-supportive-care-for-advanced-gastric-cancer
#7
Hyun Cheol Chung, Victor C Kok, Rebecca Cheng, Yanzhi Hsu, Mauro Orlando, Charles Fuchs, Jae Yong Cho
AIM: We describe a subgroup analysis assessing the efficacy and safety of ramucirumab monotherapy in East Asian (EA) patients from the REGARD trial. METHODS: Patients with advanced gastric or gastroesophageal junction adenocarcinoma with progressive disease were randomized 2:1 to receive ramucirumab (8 mg/kg) plus best supportive care (BSC) or placebo plus BSC every 2 weeks. Post hoc subset analyses were performed on the EA and non-EA intention-to-treat populations...
January 10, 2018: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29310210/a-new-and-simple-method-for-the-simultaneous-determination-of-amoxicillin-and-nimesulide-using-carbon-black-within-a-dihexadecylphosphate-film-as-electrochemical-sensor
#8
Patrícia B Deroco, Romeu C Rocha-Filho, Orlando Fatibello-Filho
The first electroanalytical method for the simultaneous determination of an important antibiotic (amoxicillin - AMX) and an anti-inflammatory drug (nimesulide -NIM), widely used in combination, is here proposed. In this method, a glassy carbon (GC) substrate modified with carbon black (CB) immobilized within a dihexadecylphosphate (DHP) film is used as electrochemical sensor (CB-DHP/GC). The electrochemical activity of this sensor was assessed (comparatively to that of GC) by electrochemical impedance spectroscopy, using the [Fe(CN)6]3-/4- redox couple, when two different active electron transfer regions were clearly characterized...
March 1, 2018: Talanta
https://www.readbyqxmd.com/read/29304781/evaluation-of-endoglin-cd105-expression-in-pediatric-rhabdomyosarcoma
#9
Virginia Di Paolo, Ida Russo, Renata Boldrini, Lucilla Ravà, Marco Pezzullo, Maria Chiara Benedetti, Angela Galardi, Marta Colletti, Rossella Rota, Domenico Orlando, Alessandro Crocoli, Hector Peinado, Giuseppe Maria Milano, Angela Di Giannatale
BACKGROUND: The Intratumoral Microvessel Density (IMVD) is commonly used to quantify tumoral vascularization and is usually assessed by pan-endothelial markers, such as CD31. Endoglin (CD105) is a protein predominantly expressed in proliferating endothelium and the IMVD determined by this marker measures specifically the neovascularization. In this study, we investigated the CD105 expression in pediatric rhabdomyosarcoma and assessed the neovascularization by using the angiogenic ratio IMVD-CD105 to IMVD-CD31...
January 5, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29303529/dissecting-superior-cerebellar-artery-aneurysm-spontaneous-resolution-in-a-long-term-follow-up
#10
Marcos Vinicius Tadao Fujino, Rogério Iquizli, Thiago Abud, Carlos Eduardo Baccin, Gisele Sampaio Silva, Orlando G Barsottini, José Luiz Pedroso
No abstract text is available yet for this article.
October 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29299771/vibrio-coralliirubri-sp-nov-a-new-species-isolated-from-mucus-of-red-coral-corallium-rubrum-collected-at-procida-island-italy
#11
Annarita Poli, Ida Romano, Vincenza Mastascusa, Lorena Buono, Pierangelo Orlando, Barbara Nicolaus, Luigi Leone, Kar Wai Hong, Kok-Gan Chan, Kian Mau Goh, Javier Pascual
Strain Corallo1T was isolated from mucus of red coral (Corallium rubrum) at Punta Pizzaco (Procida island, Naples, Italy). It was characterised as a Gram-stain negative, motile, rod-shaped bacterium. Strain Corallo1T was found to show positive responses for cytochrome-c oxidase, catalase, reduction of nitrate and nitrite, β-galactosidase activity and hydrolysis of starch, xylan, peptone, Tween 40, Tween 80 and casein. Strain Corallo1T was found to be mesophilic, neutrophilic to alkalophilic and slightly halophilic...
January 3, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29291172/the-american-college-of-academic-international-medicine-2017-consensus-statement-on-international-medical-programs-establishing-a-system-of-objective-valuation-and-quantitative-metrics-to-facilitate-the-recognition-and-incorporation-of-academic-international
#12
Gregory L Peck, Manish Garg, Bonnie Arquilla, Vicente H Gracias, Harry L Anderson Iii, Andrew C Miller, Bhakti Hansoti, Paula Ferrada, Michael S Firstenberg, Sagar C Galwankar, Ramon E Gist, Donald Jeanmonod, Rebecca Jeanmonod, Elizabeth Krebs, Marian P McDonald, Benedict Nwomeh, James P Orlando, Lorenzo Paladino, Thomas J Papadimos, Robert L Ricca, Joseph V Sakran, Richard P Sharpe, Mamta Swaroop, Stanislaw P Stawicki
The growth of academic international medicine (AIM) as a distinct field of expertise resulted in increasing participation by individual and institutional actors from both high-income and low-and-middle-income countries. This trend resulted in the gradual evolution of international medical programs (IMPs). With the growing number of students, residents, and educators who gravitate toward nontraditional forms of academic contribution, the need arose for a system of formalized metrics and quantitative assessment of AIM- and IMP-related efforts...
October 2017: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29290322/-nevus-lipomatosus-cutaneous-superficialis-report-of-four-cases-including-an-unusual-presentation-associated-with-massive-lipomas-and-diffuse-lipomatosis
#13
Mariana Medell-Gago, Tamara Guerra-Guerra, Orlando González-Pérez, Leonardo Concepción-Quiñones
Nevus lipomatosus cutaneus superficialis is a rare, hamartomatous disorder, characterized by the presence of ectopic mature adipose tissue within the superficial dermis. Lesions occur within the first three decades of life. We report four new cases, including a patient with the most extensive affectation reported to date, which was associated with massive lipomas in the subcutaneous cell tissue and diffuse lipomatosis. To our knowledge, it is the first report of this disorder in Cuba.
January 2018: Revista Española de Patología
https://www.readbyqxmd.com/read/29290253/dynamic-change-of-fatigue-of-pemetrexed-maintenance-treatment-in-the-jmen-trial
#14
Li Zhang, Chandra P Belani, Ping-Hai Zhang, Xin Wang, Lulu Yang, Mauro Orlando, Yi-Long Wu
OBJECTIVES: In the JMEN trial, patients with advanced non-squamous non-small cell lung cancer (NSCLC) without progression after platinum-based first-line therapy derived extended survival, delayed disease progression, and maintained overall quality of life (QoL) from pemetrexed maintenance therapy. However, fatigue was the most common physician-reported non-hematological toxicity in the pemetrexed group. This post hoc analysis investigated dynamic change of fatigue. MATERIALS AND METHODS: Analysis of the overall safety population with squamous and non-squamous NSCLC subgroups included Common Terminology Criteria for Adverse Events to summarize adverse event (AE) rates by cycle and AE investigator-reported severity...
January 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29290171/health-care-costs-and-thromboembolic-events-in-hydroxyurea-treated-patients-with-polycythemia-vera
#15
Shreekant V Parasuraman, Nianwen Shi, Dilan C Paranagama, Machaon Bonafede
BACKGROUND: Patients with polycythemia vera (PV) are at increased risk of thromboembolic events (TEs), which are key contributors to reduced overall survival compared with the age- and sex-matched general population. In addition to aspirin and phlebotomy to maintain hematocrit level < 45%, many patients receive cytoreduction with hydroxyurea (HU), which is associated with improved survival and may reduce the risk of cardiovascular events and TEs. However, 1 in 4 patients become resistant to or intolerant of HU...
January 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29287812/the-true-ponte-osteotomy-by-the-one-who-developed-it
#16
Alberto Ponte, Giuseppe Orlando, Gian Luigi Siccardi
STUDY DESIGN: Technique and applications. OBJECTIVES: To define the anatomy, biomechanics, indications, and surgical technique of the true Ponte osteotomy. SUMMARY OF BACKGROUND DATA: The Ponte osteotomy, originally developed for thoracic kyphosis, was the first one to obtain posterior shortening of the thoracic spine, maintaining the anterior column load-sharing capacity. It has become a widely applied technique in various types of spine deformities and a frequent topic of presentations at meetings and in scientific articles...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29285808/is-prolonged-cold-ischemia-a-contraindication-to-using-kidneys-from-acute-kidney-injury-donors
#17
Giuseppe Orlando, Muhammad A Khan, Hany El-Hennawy, Alan C Farney, Jeffrey Rogers, Amber Reeves-Daniel, Michael D Gautreaux, William Doares, Scott Kaczmorski, Robert J Stratta
To determine the impact of prolonged cold ischemia time (CIT) on the outcome of acute kidney injury (AKI) renal grafts, we therefore performed a single center retrospective analysis in adult patients receiving kidney transplantation (KT) from AKI donors. Outcomes were stratified according to duration of CIT. 118 patients receiving AKI grafts were enrolled. Based on CIT, patients were stratified as follows: a) <20 hours, 27 patients; b) 20-30 hours, 52 patients; c) 30-40 hours, 30 patients; ≥40 hours, 9 patients...
December 28, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29284681/a-novel-aggf1-pdgfr%C3%AE-fusion-in-pediatric-t-cell-acute-lymphoblastic-leukemia
#18
Matthew S Zabriskie, Orlando Antelope, Anupam R Verma, Lauren R Draper, Christopher A Eide, Anthony D Pomicter, Thai Hoa Tran, Brian J Druker, Jeffrey W Tyner, Rodney R Miles, James M Graham, Jae-Yeon Hwang, Katherine E Varley, Reha M Toydemir, Michael W Deininger, Elizabeth A Raetz, Thomas O'Hare
No abstract text is available yet for this article.
December 28, 2017: Haematologica
https://www.readbyqxmd.com/read/29281114/serum-albumin-concentration-and-risk-of-end-stage-renal-disease-the-regards-study
#19
Carl P Walther, Orlando M Gutiérrez, Mary Cushman, Suzanne E Judd, Joshua Lang, William McClellan, Paul Muntner, Mark J Sarnak, Michael G Shlipak, David G Warnock, Ronit Katz, Joachim H Ix
Background: Serum albumin concentration is a commonly available biomarker with prognostic value in many disease states. It is uncertain whether serum albumin concentrations are associated with incident end-stage renal disease (ESRD) independently of urine albumin-to-creatinine ratio (ACR). Methods: A longitudinal evaluation was performed of a population-based community-living cohort from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study...
December 20, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29280060/minimally-invasive-approach-robotic-and-laparoscopic-to-biliary-enteric-fistula-secondary-to-cholecystectomy-bile-duct-injury
#20
Adolfo Cuendis-Velázquez, Mario E Trejo-Ávila, Andrés Rodríguez-Parra, Orlando Bada-Yllán, Carlos Morales-Chávez, Luis Fernández-Álvarez, Eduardo Cárdenas-Lailson, Sujey Romero-Loera, Martin Rojano-Rodríguez, Mucio Moreno-Portillo
Spontaneous biliary-enteric fistula after laparoscopic cholecystectomy bile duct injury is an extremely rare entity. Y-en-Roux hepaticojejunostomy has been demonstrated to be an effective surgical technique to repair iatrogenic bile duct injuries. Seven consecutive patients underwent robotic-assisted (n = 5) and laparoscopic (n = 2) biliary-enteric fistula resection and bile duct repair at our hospital from January 2012 to May 2017. We reported our technique and described post-procedural outcomes. The mean age was 52...
December 26, 2017: Journal of Robotic Surgery
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