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Central serous choroidopathy

Julie M Rosenthal, Mark W Johnson
Pregnancy leads to significant changes in the body, which potentially affect the retina. Pregnancy can induce disease, such as that seen in hypertensive retinopathy and choroidopathy. It can cause exudative retinal detachments in the HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), disseminated intravascular coagulation (DIC), and thrombotic thrombocytopenic purpura (TTP), and provoke arterial and venous retinal occlusive disease. Pregnancy may also exacerbate pre-existing retinal disease, such as idiopathic central serous chorioretinopathy (ICSC) and diabetic retinopathy...
January 2018: Journal of Ophthalmic & Vision Research
Murat Hasanreisoglu, Gokcen D Gulpinar Ikiz, Hamit Kucuk, Ozkan Varan, Sengul Ozdek
IMPORTANCE: Systemic lupus erythematosus (SLE) is a thoroughly examined multi-organ disease whose common ocular complications are also well documented. However, SLE choroidopathy, being a rare ocular complication, is needed to be better understood, in order to make the differential diagnosis from clinical conditions such as central serous chorioretinopathy and provide adequate prompt treatment. OBJECTIVE: To provide a clear understanding for the clinical course of SLE choroidopathy by the help of enhanced depth imaging optical coherence tomography, fluorescein angiography, and indocyanine angiography...
February 2018: International Ophthalmology
Annelies Fabry, Johan Blanckaert, Anita Leys
OBJECTIVE: To report chronic central serous choroidopathy with severe visual loss in hyperopic microphthalmic identical twins. METHODS: The index patient was first examined in 1994, at age 31, and has been followed up closely for 17 years. He had repeated fluorescein and indocyanine green angiograms, OCT, ultrasound biometry, and recently also autofluorescence and EDI OCT. His twin brother was first examined in 2010, at age 47, and had a similar extensive exploration...
2011: GMS Ophthalmology Cases
Sergio Eustolio Hernández-Da Mota
BACKGROUND: Central serous choroidopathy is a macular disease, usually with a self-limited and benign course, and predominantly affects male patients between 20 and 45 years old. CLINICAL CASE: A 68 year-old female patient complained of decreased visual acuity of her right eye of approximately 3 weeks of onset. Best corrected visual acuity in her right eye was 20/100. Fundus examination revealed a macular serous detachment involving its centre, as well as the presence of multiple calcified drusen...
July 2016: Cirugia y Cirujanos
Young Soo Han, Chan min Yang, Sang-Hoon Lee, Jae Ho Shin, Sang Woong Moon, Ja Heon Kang
BACKGROUND: We present a rare case of secondary angle closure glaucoma due to systemic lupus erythematosus choroidopathy as initial presentation of systemic lupus erythematosus, accompanied by central nervous system vasculitis and uncontrolled nephropathy. CASE PRESENTATION: A 31-year-old woman presented with decreased visual acuity, nausea, vomiting, fever, and bilateral angioedema-like eyelid swelling. She had persistent dry cough while taking medication for 3 months, and had usual posterior neck pain, which was treated with analgesic medication and Asian medicines...
October 29, 2015: BMC Ophthalmology
Daniela Ferrara, Nadia K Waheed, Jay S Duker
The body of knowledge of in vivo investigation of the choroid has been markedly enhanced by recent technological advances in optical coherence tomography (OCT). New insights elucidating the morphological features of the choriocapillaris and choroidal vasculature, in both physiological and pathological conditions, indicate that the choroid plays a pivotal role in many posterior segment diseases. In this article, a review of the histological characteristics of the choroid, which must be considered for the proper interpretation of in vivo imaging, is followed by a comprehensive discussion of fundamental principles of the current state-of-the-art in OCT, including cross-sectional OCT, en face OCT, and OCT angiography using both spectral domain OCT and swept source OCT technologies...
May 2016: Progress in Retinal and Eye Research
Codruta Blăjan, D Nicula, Ioana Rusu
The paper presents the first results concerning the Aflibercept (Eylea) treatment, the last antiVEGF approved for treatment of the age related macular degeneration (AMD), neovascular form and for macular edema due to the central retinal vein occlusion. The treatment was applied to patients presenting AMD, ME and other diseases: myopic and idiopatic choroidal neovascularisation, central serous choroidopathy (CSC) or diabetic macular edema (DME). The results were good: improvement of the visual acuity, resolution of the intraretinal fluids and macular edema...
2014: Oftalmologia
Sara Torfs, Anita M Leys
BACKGROUND: Thanks to advancement in treatment modalities, the medial survival rate of patients with familial pulmonary arterial hypertension (FPAH) has been improved. Unfortunately, ocular complications because of the chronically elevated systemic venous pressure become more frequent. METHODS: The authors report new FPAH-associated fundus changes in a 50-year-old male patient treated with sildenafil. The anomalies were studied with autofluorescence, fluorescein and indocyanine green angiography, and spectral optical coherence tomography including enhanced depth imaging...
2013: Retinal Cases & Brief Reports
Stephen R Smith, Lee M Jampol
No abstract text is available yet for this article.
2007: Retinal Cases & Brief Reports
Joel Nelson, David D Saggau, Jared S Nielsen
PURPOSE: The purpose of this report is to present a case of hepatotoxicity secondary to off-label rifampin therapy for the treatment of chronic central serous choroidopathy. METHODS: Case report. RESULTS: A patient with chronic central serous chorioretinopathy was treated with oral rifampin. Three weeks after the initiation of therapy, fatigue, nausea, and malaise associated with elevated liver enzyme elevations were noted. Symptoms resolved and liver enzymes normalized after discontinuing rifampin...
2014: Retinal Cases & Brief Reports
Sang Jun Park, Bo Hyuck Kim, Kyu Hyung Park, Se Joon Woo
PURPOSE: To characterize punctate hyperfluorescence spot as common choroidopathy in central serous chorioretinopathy (CSC) and polypoidal choroidal vasculopathy (PCV). DESIGN: Cross-sectional retrospective study. METHODS: A total of 150 patients with 50 each allocated to CSC, PCV, and typical neovascular age-related macular degeneration (AMD) groups were included. Punctate hyperfluorescence spot was determined using mid-to late-phase indocyanine green angiography and subfoveal choroidal thickness by enhanced depth imaging optical coherence tomography...
December 2014: American Journal of Ophthalmology
Muhammet Kazim Erol, Ozdemir Ozdemir, Deniz Turgut Coban, Basak Bostanci Ceran, Mehmet Bulut
PURPOSE: To report a retrospective series of choroidal neovascularization (CNV) patients treated with intravitreal ranibizumab with good baseline vision from causes other than age-related macular degeneration (AMD). METHODS: We retrospectively reviewed 12 eyes of 12 patients with CNV secondary to non-AMD who received intravitreal ranibizumab injections. Patients with baseline best-corrected visual acuity (BCVA) above 20/63 were included in the study. All patients were followed up at least for 12 months...
March 2014: Seminars in Ophthalmology
Nathan Cleaver, James Ramirez, Stuart Gildenberg
INTRODUCTION: Bevacizumab is a recombinant humanized antibody against vascular endothelial growth factor (VEGF). It is approved by the Food and Drug Administration (FDA) for metastatic colorectal cancer, advanced non-small cell lung cancer, metastatic renal cell cancer and glioblastoma. Bevacizumab has also been used off label in ophthalmology for age-related macular degeneration, diabetic retinopathy, retinal vein occlusions, retinopathy of prematurity, and other chorioretinal vascular disorders...
September 2013: Journal of Drugs in Dermatology: JDD
Josef Flammer, Katarzyna Konieczka, Andreas J Flammer
Vascular dysregulation refers to the regulation of blood flow that is not adapted to the needs of the respective tissue. We distinguish primary vascular dysregulation (PVD, formerly called vasospastic syndrome) and secondary vascular dysregulation (SVD). Subjects with PVD tend to have cold extremities, low blood pressure, reduced feeling of thirst, altered drug sensitivity, increased pain sensitivity, prolonged sleep onset time, altered gene expression in the lymphocytes, signs of oxidative stress, slightly increased endothelin-1 plasma level, low body mass index and often diffuse and fluctuating visual field defects...
June 7, 2013: EPMA Journal
Lihong Yang, Jost B Jonas, Wenbin Wei
PURPOSE: To measure the hyporeflective lumen in the choroid of patients with central serous choroidopathy (CSC) and to compare the diameter with that of a control group. METHODS: The prospective comparative observational clinical study included patients with unilateral CSC and a control group of normal subjects, matched in age, gender and refractive error with the study group. Subfoveal choroidal thickness (SFCT) and the largest diameter of choroidal hyporeflective lumen as surrogates for the choroidal vessels were measured by enhanced depth imaging optical coherence tomography (OCT)...
August 2013: Acta Ophthalmologica
Marie-Hélène Errera, Radha P Kohly, Lyndon da Cruz
Pregnancy-associated retinal diseases are conditions that may occur uniquely in pregnancy or, more commonly, general conditions that may worsen or alter during pregnancy as a result of hematologic, hormonal, metabolic, cardiovascular, and immunologic changes. Diabetic retinopathy (DR) is by far the most common retinal condition that is altered by pregnancy. However, there are currently no widely accepted, precise clinical guidelines regarding its management during pregnancy. At present it is not possible to predict who will regress and who will progress without treatment...
March 2013: Survey of Ophthalmology
C Ciamberlini, V Guarnieri, G Longobardi, P Poggi, M C Donati, G Panzardi
No abstract text is available yet for this article.
April 1997: Journal of Biomedical Optics
Ioannis P Theocharis, Luiz H Lima
PURPOSE: To investigate the frequency and patterns of vitreoretinal adherence in central serous choroidopathy (CSC) using spectral domain optical coherence tomography (SD-OCT) imaging and compare them with normal subject. METHODS: A descriptive observational analytical retrospective case-control study. The study patients were split into non-chronic and chronic CSC groups and compared with an age- and gender-matched control group composed of healthy individuals without CSC...
November 2012: Acta Ophthalmologica
Tuğba Göncü, Sengül Ozdek
BACKGROUND: Bilateral multiple serous retinal pigment epithelial detachments (PEDs) are a very rare entity. Such conditions may be idiopathic or a presentation of some ocular and/or systemic pathologies. We report 2 unique cases of bilateral multiple serous PEDs without any known cause. Additionally, similar cases of multiple serous idiopathic PEDs reported in the literature were reviewed. CASE REPORT: The patients were middle-age women with no known related ocular and systemic problems...
September 2011: Optometry: Journal of the American Optometric Association
Bt Ozturk, B Bozkurt, Z Karademir, H Kerimoglu
A 36-year-old female followed with the diagnosis of systemic lupus erythematosus complained of bilateral visual loss. Ophthalmological examination revealed disc edema with irregular borders, edematous and pale retina with widespread cotton wool spots, intraretinal hemorrhages and serous retinal detachment in both eyes. Optical coherence tomography (OCT) scans showed intraretinal and subretinal fluid creating cystic cavities with central subfield macular thickness values of 994 and 912( )µm in the right and left eye, respectively...
October 2011: Lupus
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