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Andrew Shaw, Thomas VandeVen
PURPOSE OF REVIEW: The field of perioperative genomics is developing rapidly, and by now most practitioners are familiar with the idea that the host response to surgery and trauma is at least in part genetically determined. The precise way in which genetic variation affects outcomes after injury and surgical treatment is not known however. This review considers recent advances in thinking in the domain of perioperative genomics. RECENT FINDINGS: Genome wide association studies (GWAS) have been conducted in tens of thousands of patients at enormous cost, using phenotypes of varying complexity and clarity...
August 2010: Current Opinion in Critical Care
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