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Mikael Simm, Ewa Söderberg, Anders Larsson, Markus Castegren, Tom Nilsen, Mats Eriksson, Miklos Lipcsey
AIM: To determine the performance of plasma calprotectin as a marker of sepsis on intensive care unit (ICU) admission and as a marker of mortality day 30 post-ICU admission. MATERIALS & METHODS: Consecutive ICU patients were allocated to: sepsis (n = 15), postoperative inflammation (n = 23) and intoxication without inflammation (n = 7) groups. RESULTS: Calprotectin was 4.3 (2.6-8.2; mg/l; median [interquartile range]) in the sepsis, 2.8 (1...
August 2016: Biomarkers in Medicine
Lanocha Aleksandra, Zdziarska Barbara, Lanocha-Arendarczyk Natalia, Kosik-Bogacka Danuta, Guzicka-Kazimierczak Renata, Marzec-Lewenstein Ewa
In industrialized countries, risk groups for parasitic diseases include travelers, recent immigrants, and patients with immunodeficiency following chemotherapy and radiotherapy and AIDS. A 66-year-old Polish male was admitted in December 2012 to the Department of Haematology in a fairly good general condition. On the basis of cytological, cytochemical, immunophenotypic, and cytogenetic analysis of bone marrow, the patient was diagnosed with acute myeloblastic leukemia. On the 7th day of hospitalization in the Department of Haematology, patient was moved to the Intensive Care Unit (ICU) due to acute respiratory and circulatory failure...
2016: Case Reports in Infectious Diseases
Wiesława Duszyńska, Victor D Rosenthal, Aleksander Szczęsny, Ewa Woźnica, Klaudia Ulfik, Elżbieta Ostrowska, Agnieszka Litwin, Andrzej Kübler
BACKGROUND: Urinary tract infections (UTI) in patients with urinary catheters could be a serious complication of hospitalisation in the intensive care unit (ICU). METHODS: A prospective study (01.01.2012-31.12.2014) was conducted in the 20-bed ICU of the University Hospital in Wroclaw, Poland. The frequency (density, incidence) and aetiology of UTI as well as prophylactic method compliance were estimated in patients of the ICU according to the INICC project. RESULTS: Among 1261 ICU patients, urinary tract infections were diagnosed in 91 (7%)...
2016: Anaesthesiology Intensive Therapy
Truls Gråberg, Lovisa Strömmer, Erik Hedman, Mehmet Uzunel, Ewa Ehrenborg, Ann-Charlotte Wikström
INTRODUCTION: An assay to determine glucocorticoid (GC) responsiveness in humans could be used to monitor GC non-responsiveness in states of GC insufficiency and could provide a tool to adapt GC treatment to individual patients. We propose an ex vivo assay to test GC responsiveness in peripheral leukocytes. The assay was evaluated in a human experimental model of surgery-induced inflammation. PATIENTS AND METHODS: Changes in expression of the GC-regulated genes GILZ, IL1R2, FKBP5, and HLA-DR and glucocorticoid receptor alpha (GRα) were determined by reverse transcriptase quantitative polymerase chain reaction (RT-qPCR) in peripheral leukocytes from surgical patients and healthy blood donors (total n=60) in response to low (1 nM) and high (1 µM) dexamethasone (DEX)...
2015: Journal of Inflammation Research
Gisela Lilja, David Erlinge, Ing-Marie Larsson, Ewa Wallin, Eva Åkerman, Tobias Cronberg
The return to a good life after successfully resuscitated cardiac arrest may be hindered by cardiovascular morbidity, psychological distress and the consequences of anoxic brain injury. To support the return to everyday life, patients and their relatives are in need of health care follow-up with multiple focuses. Usually, this follow-up consists of at least one of three parallel tracks; cardiology for interventions and secondary prevention, post intensive care follow-up to capture and prevent consequences of the traumatic event and the ICU stay, or neurological follow-up for patients with neurological sequels...
2015: Läkartidningen
Jan Adamski, Radosław Goraj, Dariusz Onichimowski, Ewa Gawlikowska, Wojciech Weigl
BACKGROUND: The aim of this study was to evaluate possible differences in the functioning of two selected intensive care units in Poland and Finland. The activity of the units was analysed over a period of one year. METHODS: The following parameters were compared: demography of treated populations, site of admission, category of illness, severity of illness (APACHE-II scale), mean length of stay, demanded workload (TISS-28 scale), mortality (both ICU and hospital) and standardized mortality ratio (SMR)...
2015: Anaesthesiology Intensive Therapy
Andrzej Kübler, Barbara Adamik, Grażyna Durek, Ewa Mayzner-Zawadzka, Wojciech Gaszyński, Ewa Karpel, Wiesława Duszyńska
BACKGROUND: Severe sepsis remains the most common cause of death in intensive care units (ICUs) according to many epidemiological studies. There are no data in Poland on the extent of severe sepsis cases treated in ICUs. The aim of the study was to analyse the course and outcome of severe sepsis patients treated in Polish ICUs. METHODS: In 2003, the internet-based severe sepsis registry was created as a multicentre observational research project. An online questionnaire was made accessible to ICUs participating in the study...
2015: Anaesthesiology Intensive Therapy
Ewa Tyczkowska-Sieroń, Anna Bartoszko-Tyczkowska, Wojciech Gaszyński
INTRODUCTION: The objective of this study was to analyze the fungal infections in patients of an intensive care unit (ICU) in a long period (2002-2012) on the example of the Lodz Medical University Hospital No 1. This analysis was focused on the study of the effect of antimicrobial therapy on the level of these infections. METHODS: A total of 291 strains of fungi were isolated from blood, tips of central intravenous catheters, lower respiratory tract, urine, wounds, pressure sores, and cerebrospinal fluid of 3177 patients...
2014: Medycyna Doświadczalna i Mikrobiologia
Ing-Marie Larsson, Ewa Wallin, Sten Rubertsson, Marja-Leena Kristoferzon
AIM: To describe relatives' experiences during the next of kin's hospital stay after surviving a cardiac arrest (CA) treated with hypothermia at an intensive care unit (ICU). METHODS: Twenty relatives were interviewed when the person having suffered the CA was discharged from hospital, 1.5 to 6 weeks post-CA. Data were analysed using qualitative content analysis. RESULTS: Three themes are described: The first period of chaos, Feeling secure in a difficult situation, and Living in a changed existence...
August 2013: European Journal of Cardiovascular Nursing
Błażej Michalski, Jarosław D Kasprzak, Ewa Szymczyk, Piotr Lipiec
BACKGROUND: The pocket echocardiograph (PE) with color Doppler imaging belongs to a new class of diagnostic tools, the feasibility and accuracy of which is not well established. The aim of this study was to assess the feasibility and diagnostic value of transthoracic echocardiography (TTE) performed with the use of PE by a cardiology resident (2nd year of training) and by an experienced cardiologist. METHODS: The study population comprised 220 consecutive patients (142 men, mean age 63 ± 8 years), 110 of whom were admitted to our intensive cardiac care unit (ICU) and 110 patients referred for TTE from the outpatient clinic...
2012: Echocardiography
Andrzej Kübler, Wieslawa Duszynska, Victor D Rosenthal, Malgorzata Fleischer, Teresa Kaiser, Ewa Szewczyk, Barbara Barteczko-Grajek
PURPOSE: The aim of this study was to determine device-associated health care-associated infections (DA-HAI) rates, microbiologic profile, bacterial resistance, and length of stay in one intensive care unit (ICU) of a hospital member of the International Nosocomial Infection Control Consortium (INICC) in Poland. MATERIALS AND METHODS: A prospective DA-HAI surveillance study was conducted on an adult ICU from January 2007 to May 2010. Data were collected by implementing the methodology developed by INICC and applying the definitions of DA-HAI provided by the National Healthcare Safety Network at the US Centers for Disease Control and Prevention...
February 2012: Journal of Critical Care
Ingrid Wåhlin, Anna-Christina Ek, Ewa Idvall
AIM: The purpose of the study was to describe empowerment from the perspective of intensive care staff. What makes intensive care staff experience inner strength and power? BACKGROUND: Intensive care staff are repeatedly exposed to traumatic situations and demanding events, which could result in stress and burnout symptoms. A higher level of psychological empowerment at the workplace is associated with increased work satisfaction and mental health, fewer burnout symptoms and a decreased number of sick leave days...
October 2010: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Sebastian Sobiech, Dariusz Onichimowski, Ewa Gawlikowska
UNLABELLED: Mortality as a result of cervical spine injuries is predominantly associated with respiratory complications. Besides atelectasis, pneumonia, or respiratory failure, possible complications also include damage to anatomical structures of the respiratory tract. CASE REPORT: We present the case of a 44-year-old man who suffered a cervical spine injury with associated tracheal laceration after a fall from a height of about 2 meters. Vertebrae C3, C4, C5 were damaged with anterior dislocation at the C3/C4 level...
March 2010: Ortopedia, Traumatologia, Rehabilitacja
Anna Bartoszko-Tyczkowska, Wojciech Gaszyński, Ewa Tyczkowska-Sieroń
In the period of 2002-2006, total 5152 isolates were obtained from 1330 patients in the Intensive Care Unite (ICU) of the Lodz Medical University Hospital No.1. A detailed analysis of the epidemiological situation concerned, first of all, MRSA, Ps. aeruginosa, Acinetobacter and Enterobacteriacae. As a result of extended action aimed at reducing the infections caused by these pathogens, a permanent improvement of the epidemiological situation in the ICU was observed in 2005-2006. However, in spite of a decrease in the total number of the infections, the concentration of ESBL(+) and carbapene-resistant strains increased...
2008: Medycyna Doświadczalna i Mikrobiologia
Anna Bartoszko-Tyczkowska, Wojciech Gaszyński, Ewa Tyczkowska-Sieroń
The presence of multiresistant pathogens in a hospital leads very often to a severe sepsis that threatens the patients' life. For this reason, in the interests of the patients in the Intensive Care Unite (ICU) of the Lodz Medical University Hospital No.1, a wide monitoring of the epidemiological situation and the rational antibiotic therapy, taking the resistance mechanisms of pathogens into account, have been started since 2002. Restrictive procedures of the insertion of central venous and dialysis catheters were elaborated as well as the permanent monitoring of the MRSA carrier state among the medical staff was undertaken...
2008: Medycyna Doświadczalna i Mikrobiologia
Ewa Trejnowska, Marc J Popovich
No abstract text is available yet for this article.
2009: International Anesthesiology Clinics
Ewa Karpel, Anna Kunsdorf-Wnuk, Ewa Musioł, Anna Skorupa, Danuta Arct-Danielak, Urszula Jarosz
UNLABELLED: Colonization of the tip of the intravenous catheter is often observed in the ICU practice and can be the source of dangerous bacteriemia (CRBSI--catheter related bloodstream bacteraemia) and sepsis with multiorgan failure. There are many cases conected with bacterial colonization of the tip of the catheter in the ICU practice, which could be the source of dangerous bacteriemia--CRBSI (catheter related bloodstream bacteriemia) and sepsis with organs failure. MATERIAL AND METHODS: 105 patients with sepsis were examined, which clinical state pointed, that CVC was the source of infection...
September 2006: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Beata Toczyłowska, Małgorzata Chalimoniuk, Magdalena Wodowska, Ewa Mayzner-Zawadzk
Brain injury, like other central nervous system pathologies, causes changes in the composition of the cerebrospinal fluid (CSF). In this study, changes in the concentration of small molecules of the CSF, which are in the minimal micromolar concentration, were observed and monitored using high-resolution proton (NMR) spectroscopy. Twenty-two patients with isolated traumatic brain injuries (TBI) and 15 patients making up the control group were recruited for the study. CSF samples were collected by lumbar puncture from the lumbar subarachnoid space in the patients just before commencement of therapy and on the first, third, seventh and fourteenth days of therapy at the ICU...
August 9, 2006: Brain Research
Tomasz Siegel, Małgorzata Mikaszewska-Sokolewicz, Ewa Mayzner-Zawadzka
OBJECTIVES: Infections at the Intensive Care Units (ICU) are a substantial clinical problem due to their high incidence and significant impact on patient mortality, as well as on the duration of their treatment within ICUs. The objective of the present study was to analyse the infections occurring at our department and to identify those micro-organisms responsible for infections, with consideration of their susceptibility to antibiotic treatment. Moreover, an evaluation was performed in respect of correlation between infection incidence, patient mortality and duration of stay at the department...
March 2006: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Anna Jander, Michaeł Nowicki, Marcin Tkaczyk, Maria Roszkowska-Blaim, Tomasz Jarmoliński, Ewa Marczak, Ewa Pałuba, Jacek A Pietrzyk, Grzegorz Siteń, Roman Stankiewicz, Krystyna Szprynger, Maria Zajaczkowska, J Zachwieja, W Zoch-Zwierz, D Zwolińska
BACKGROUND: It is estimated that 20-50% of adult patients start chronic dialysis therapy without prior contact with a nephrologist. The aim of this nationwide study was to assess clinical and metabolic status of children at the start of chronic dialysis in Poland with regard to the timing of the referral to a nephrologist. METHODS: We studied data of 180 children (mean age 14+/-6 years) undergoing chronic dialysis in 13 (out of 14) dialysis pediatric centres in Poland...
April 2006: Nephrology, Dialysis, Transplantation
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