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LEAN quality improvement

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https://www.readbyqxmd.com/read/29324550/effectiveness-of-the-lean-process-compared-to-other-quality-improvement-initiatives-on-length-of-stay-and-wait-times-in-healthcare-organizations-a-systematic-review-protocol
#1
Lisa C Honeycutt, Sheila D Keller
What is the effectiveness of the Lean process compared to other quality improvement initiatives on length of stay and wait times in healthcare organizations?
January 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29316987/diet-nutrition-and-the-ageing-brain-current-evidence-and-new-directions
#2
Katie Moore, Catherine F Hughes, Mary Ward, Leane Hoey, Helene McNulty
Globally populations are ageing. By 2050, it is estimated that there will be two billion people aged 60 years or over, of which 131 million are projected to be affected by dementia, while depression is predicted to be the second leading cause of disability worldwide by 2020. Preventing or delaying the onset of these disorders should therefore be a public health priority. There is some evidence linking certain dietary patterns, particularly the Mediterranean diet, with a reduced risk of dementia and depression...
January 10, 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29315350/gluteal-muscle-damage-leads-to-higher-in-vivo-hip-joint-loads-3-months-after-total-hip-arthroplasty
#3
Philipp Damm, Jip Zonneveld, Sophie Brackertz, Florian Streitparth, Tobias Winkler
BACKGROUND: Total hip arthroplasty (THA) is in most cases improving patients´ life quality immediately after surgery. However, a closer look at these patients, especially with modern gait analysis methods, reveals also negative consequences due to the surgical approach related injury to the pelvic muscles. We hypothesized that this damage will have a negative impact on hip joint contact forces during activities of daily living (ADL). METHODS: 10 patients undergoing THA received an instrumented hip joint implant enabling real time in vivo measurements of hip joint loads using a direct lateral approach...
2018: PloS One
https://www.readbyqxmd.com/read/29315169/health-benefits-of-an-innovative-exercise-program-for-mitochondrial-disorders
#4
Carmen Fiuza-Luces, Jorge Díez-Bermejo, Miguel Fernández-de la Torre, Gabriel Rodríguez-Romo, Paz Sanz-Ayán, Aitor Delmiro, Diego Munguía-Izquierdo, Irene Rodríguez-Gómez, Ignacio Ara, Cristina Domínguez-González, Joaquín Arenas, Miguel A Martín, Alejandro Lucia, María Morán
PURPOSE: We determined the effects of an innovative 8-week exercise intervention (aerobic, resistance and inspiratory muscle training) for patients with mitochondrial disease (MD). METHODS: Several endpoints were assessed in 12 patients (19-59 years, 4 female) at pre-training, post-training and after 4-week detraining: aerobic power, muscle strength/power and maximal inspiratory pressure (main endpoints), ability to perform activities of daily living (ADL), body composition, quality of life and blood myokines (secondary endpoints)...
January 8, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29224861/a-survey-of-selected-animal-based-measures-of-dairy-cattle-welfare-in-the-eastern-alps-toward-context-based-thresholds
#5
A Zuliani, M Mair, M Kraševec, I Lora, M Brscic, G Cozzi, C Leeb, M Zupan, C Winckler, S Bovolenta
In the Alps, traditional dairy farms are small-scale operations where vertical transhumance from valley indoor housing systems to highland pasture-based systems is still practiced in summer. Vertical transhumance implies a substantial change of environment, available resources, and management practices from one season to another. In such systems, animal-based welfare measures need to be monitored throughout the year to capture the variation of welfare outcomes, based on which targeted welfare management plans can be implemented...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29221645/primary-care-led-weight-management-for-remission-of-type-2-diabetes-direct-an-open-label-cluster-randomised-trial
#6
Michael Ej Lean, Wilma S Leslie, Alison C Barnes, Naomi Brosnahan, George Thom, Louise McCombie, Carl Peters, Sviatlana Zhyzhneuskaya, Ahmad Al-Mrabeh, Kieren G Hollingsworth, Angela M Rodrigues, Lucia Rehackova, Ashley J Adamson, Falko F Sniehotta, John C Mathers, Hazel M Ross, Yvonne McIlvenna, Renae Stefanetti, Michael Trenell, Paul Welsh, Sharon Kean, Ian Ford, Alex McConnachie, Naveed Sattar, Roy Taylor
BACKGROUND: Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed to assess whether intensive weight management within routine primary care would achieve remission of type 2 diabetes. METHODS: We did this open-label, cluster-randomised trial (DiRECT) at 49 primary care practices in Scotland and the Tyneside region of England. Practices were randomly assigned (1:1), via a computer-generated list, to provide either a weight management programme (intervention) or best-practice care by guidelines (control), with stratification for study site (Tyneside or Scotland) and practice list size (>5700 or ≤5700)...
December 4, 2017: Lancet
https://www.readbyqxmd.com/read/29221501/lean-methodology-reduces-inappropriate-use-of-antipsychotics-for-agitation-at-a-psychiatric-hospital
#7
Joshana K Goga, Antonio Depaolo, Sunil Khushalani, J Ken Walters, Robert Roca, Marc Zisselman, Christopher Borleis
OBJECTIVE: To Evaluate the Effects of Applying Lean Methodology-Improving Quality Increasing Efficiency by Eliminating Waste and Reducing Costs-An Approach To Decrease the Prescribing Frequency of Antipsychotics for The Indication of Agitation. DESIGN: Historically Controlled Study. SETTING: Bheppard Pratt Health System is the Largest Private Provider of Psychiatric Care in Maryland With a Total Bed Capacity of 300. There Were 4 337 Patient Days From November 1 2012 to October 31 2013 on the Dementia Unit...
January 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29209277/exenatide-improves-bone-quality-in-a-murine-model-of-genetically-inherited-type-2-diabetes-mellitus
#8
Marie Pereira, Stephanie Gohin, Jean-Paul Roux, Amy Fisher, Mark E Cleasby, Guillaume Mabilleau, Chantal Chenu
Type 2 diabetes mellitus (T2DM) is associated with skeletal complications, including an increased risk of fractures. Reduced blood supply and bone strength may contribute to this skeletal fragility. We hypothesized that long-term administration of Exenatide, a glucagon-like peptide-1 receptor agonist, would improve bone architecture and strength of T2DM mice by increasing blood flow to bone, thereby stimulating bone formation. In this study, we used a model of obesity and severe T2DM, the leptin receptor-deficient db/db mouse to assess alterations in bone quality and hindlimb blood flow and to examine the beneficial effects of 4 weeks administration of Exenatide...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29205286/anamorelin-ono-7643-for-the-treatment-of-patients-with-non-small-cell-lung-cancer-and-cachexia-results-from-a-randomized-double-blind-placebo-controlled-multicenter-study-of-japanese-patients-ono-7643-04
#9
Nobuyuki Katakami, Junji Uchino, Takuma Yokoyama, Tateaki Naito, Masashi Kondo, Kouzo Yamada, Hiromoto Kitajima, Kozo Yoshimori, Kazuhiro Sato, Hiroshi Saito, Keisuke Aoe, Tetsuya Tsuji, Yuichi Takiguchi, Koichi Takayama, Naoyuki Komura, Toru Takiguchi, Kenji Eguchi
BACKGROUND: Cachexia, described as weight loss (mainly in lean body mass [LBM]) and anorexia, is common in patients with advanced cancer. This study examined the efficacy and safety of anamorelin (ONO-7643), a novel selective ghrelin receptor agonist, in Japanese cancer patients with cachexia. METHODS: This double-blind clinical trial (ONO-7643-04) enrolled 174 patients with unresectable stage III/IV non-small cell lung cancer (NSCLC) and cachexia in Japan. Patients were randomized to daily oral anamorelin (100 mg) or a placebo for 12 weeks...
December 4, 2017: Cancer
https://www.readbyqxmd.com/read/29197960/sarcopenia-during-neoadjuvant-therapy-for-oesophageal-cancer-characterising-the-impact-on-muscle-strength-and-physical-performance
#10
Emer M Guinan, S L Doyle, A E Bennett, L O'Neill, J Gannon, J A Elliott, J O'Sullivan, J V Reynolds, J Hussey
PURPOSE: Preoperative chemo(radio)therapy for oesophageal cancer (OC) may have an attritional impact on body composition and functional status, impacting postoperative outcome. Physical decline with skeletal muscle loss has not been previously characterised in OC and may be amenable to physical rehabilitation. This study characterises skeletal muscle mass and physical performance from diagnosis to post-neoadjuvant therapy in patients undergoing preoperative chemo(radio)therapy for OC...
December 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29197252/oregano-dietary-supplementation-modifies-the-liver-transcriptome-profile-in-broilers-rnaseq-analysis
#11
Marcella Sabino, Stefano Capomaccio, Katia Cappelli, Andrea Verini-Supplizi, Lorenzo Bomba, Paolo Ajmone-Marsan, Gabriella Cobellis, Oliviero Olivieri, Camillo Pieramati, Massimo Trabalza-Marinucci
Intensive farming of broilers involves stressful conditions that reduce animal welfare and performance. New dietary strategies to improve performance and meat quality include the administration of plant extracts. Oregano (Origanum vulgare L.) is known for its antimicrobial, anti-fungal, insecticidal and antioxidant properties. However, studies on diet supplementation with oregano are mainly focused on the evaluation of animal performance, while partial information is available on transcriptomics and nutrigenomics and, in particular, Next Generation Sequencing (NGS) is not widely applied...
November 21, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/29192800/development-of-an-interprofessional-lean-facilitator-assessment-scale
#12
Cindy Bravo-Sanchez, Vincent Dorazio, Robert Denmark, Albert J Heuer, J Scott Parrott
High reliability is important for optimising quality and safety in healthcare organisations. Reliability efforts include interprofessional collaborative practice (IPCP) and Lean quality/process improvement strategies, which require skilful facilitation. Currently, no validated Lean facilitator assessment tool for interprofessional collaboration exists. This article describes the development and pilot evaluation of such a tool; the Interprofessional Lean Facilitator Assessment Scale (ILFAS), which measures both technical and 'soft' skills, which have not been measured in other instruments...
December 1, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29191597/anamorelin-for-advanced-non-small-cell-lung-cancer-with-cachexia-systematic-review-and-meta-analysis
#13
Kenichi Nishie, Shuhei Yamamoto, Chie Nagata, Tomonobu Koizumi, Masayuki Hanaoka
INTRODUCTION: Cancer anorexia-cachexia syndrome (CACS) is characterized by involuntary weight loss. CACS is commonly observed in advanced non-small-cell lung cancer (NSCLC), and it leads to a poor quality of life (QOL). No effective standard treatment exists for this condition. However, anamorelin has reportedly caused improvement in patients with several cancers. MATERIALS AND METHODS: We conducted a quantitative meta-analysis to explore the efficacy of anamorelin for treating CACS in patients with NSCLC...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29186013/improving-the-accessibility-and-efficiency-of-point-of-care-diagnostics-services-in-low-and-middle-income-countries-lean-and-agile-supply-chain-management
#14
REVIEW
Desmond Kuupiel, Vitalis Bawontuo, Tivani P Mashamba-Thompson
Access to point-of-care (POC) diagnostics services is essential for ensuring rapid disease diagnosis, management, control, and surveillance. POC testing services can improve access to healthcare especially where healthcare infrastructure is weak and access to quality and timely medical care is a challenge. Improving the accessibility and efficiency of POC diagnostics services, particularly in resource-limited settings, may be a promising route to improving healthcare outcomes. In this review, the accessibility of POC testing is defined as the distance/proximity to the nearest healthcare facility for POC diagnostics service...
November 29, 2017: Diagnostics
https://www.readbyqxmd.com/read/29173283/using-lean-quality-improvement-tools-to-increase-delivery-of-evidence-based-tobacco-use-treatment-in-hospitalized-neurosurgical-patients
#15
Laurel Sisler, Oluwaseun Omofoye, Karina Paci, Eldad Hadar, Adam O Goldstein, Carol Ripley-Moffitt
BACKGROUND: Health care providers routinely undertreat tobacco dependence, indicating a need for innovative ways to increase delivery of evidence-based care. Lean, a set of quality improvement (QI) tools used increasingly in health care, can help streamline processes, create buy-in for use of evidence-based practices, and lead to the identification of solutions on the basis of a problem's root causes. To date, no published research has examined the use of Lean tools in tobacco dependence...
December 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29144156/upmc-prescription-for-wellness-a-quality-improvement-case-study-for-supporting-patient-engagement-and-health-behavior-change
#16
Rebecca J Maners, Eric Bakow, Michael D Parkinson, Gary S Fischer, Geoffrey R Camp
Addressing patient health and care behaviors that underlie much of chronic disease continues to challenge providers, medical practices, health systems, and insurers. Improving health and care as described by the Quadruple Aim requires innovation at the front lines of clinical care: the doctor-patient interaction and office practice. This article describes the use of Lean Six Sigma in a quality improvement (QI) effort to design an effective and scalable method for physicians to prescribe health coaching for healthy behaviors in a primary care medical home within a large integrated delivery and financing system...
November 1, 2017: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29140299/pdgfr%C3%AE-regulated-by-mir-34a-and-foxo1-promotes-adipogenesis-in-porcine-intramuscular-preadipocytes-through-erk-signaling-pathway
#17
Yun-Mei Sun, Jin Qin, Shu-Ge Liu, Rui Cai, Xiao-Chang Chen, Xiang-Ming Wang, Wei-Jun Pang
Suitable intramuscular fat (IMF) content improves porcine meat quality. The vital genes regulating IMF deposition are necessary for the selection and breeding of an IMF trait. However, the effect and mechanism of PDGFRα on IMF deposition are still unclear. Here, PDGFRα is moderately expressed in porcine longissimus dorsi muscle (LD), whereas it highly expressed in white adipose tissue (WAT). Moreover, PDGFRα-positive cells were located in the gaps of LD fibers which there were IMF adipocytes. Compared with 180-day-old and lean-type pigs, the levels of PDGFRα were much higher in one-day-old and fat-type pigs...
November 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29137022/the-effect-of-whole-body-vibration-training-on-lean-mass-a-prisma-compliant-meta-analysis
#18
Hengting Chen, Jianxiong Ma, Bin Lu, Xin-Long Ma
BACKGROUND: Whole-body vibration training (WBVT) confers a continuous vibration stimuli to the body. Although some reports have discussed the effects of whole-body vibration (WBV) on bone mineral density and muscle strength, study of WBV effects on lean mass have not been determined. The purpose of the present meta-analysis was to evaluate published, randomized controlled trials (RCTs) that investigated the effects of WBVT on lean mass. METHODS: We identified only RCTs by searching databases, including Web of Science, PubMed, Scopus, Embase, and the Cochrane Library from inception to March 2017...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29136390/assurance-of-myeloid-growth-factor-administration-in-an-infusion-center-pilot-quality-improvement-initiative
#19
Pamela Maree Ramirez, Barry Peterson, Christine Holtshopple, Kristina Borja, Vincent Torres, Lucille Valdivia-Peppers, Julio Harriague, Melanie D Joe
PURPOSE: Four incident reports involving missed doses of myeloid growth factors (MGFs) triggered the need for an outcome-driven initiative. From March 1, 2015, to February 29, 2016, at University of California Irvine Health Chao Infusion Center, 116 of 3,300 MGF doses were missed (3.52%), including pegfilgrastim, filgrastim, and sargramostim. We hypothesized that with the application of Lean Six Sigma methodology, we would achieve our primary objective of reducing the number of missed MGF doses to < 0...
November 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29136150/using-value-stream-mapping-to-improve-quality-of-care-in-low-resource-facility-settings
#20
Rohit Ramaswamy, Claire Rothschild, Funmi Alabi, Eric Wachira, Faith Muigai, Nick Pearson
Quality problem or issue: Jacaranda Health (JH) is a Kenya-based organization that attempts to provide affordable, high-quality maternal and newborn healthcare through a chain of private health facilities in Nairobi. Initial assessment: JH needed to adopted quality improvement as an organization-wide strategy to optimize effectiveness and efficiency. Choice of solution: Value Stream Mapping, a Lean Management tool, was used to engage staff in prioritizing opportunities to improve clinical outcomes and patient-centered quality of care...
November 9, 2017: International Journal for Quality in Health Care
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