Izabela Morawska, Sara Kurkowska, Dominika Bębnowska, Rafał Hrynkiewicz, Rafał Becht, Adam Michalski, Hanna Piwowarska-Bilska, Bożena Birkenfeld, Katarzyna Załuska-Ogryzek, Ewelina Grywalska, Jacek Roliński, Paulina Niedźwiedzka-Rystwej
Selective IgA deficiency (sIgAD) is the most common primary immunodeficiency disease (PID), with an estimated occurrence from about 1:3000 to even 1:150, depending on population. sIgAD is diagnosed in adults and children after the 4th year of age, with immunoglobulin A level below 0.07 g/L and normal levels of IgM and IgG. Usually, the disease remains undiagnosed throughout the patient's life, due to its frequent asymptomatic course. If symptomatic, sIgAD is connected to more frequent viral and bacterial infections of upper respiratory, urinary, and gastrointestinal tracts, as well as autoimmune and allergic diseases...
August 25, 2021: Journal of Clinical Medicine