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human movement analysis

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https://www.readbyqxmd.com/read/29222900/comparisons-of-proteomic-profiles-of-whey-protein-between-donor-human-milk-collected-earlier-than-3-months-and-6-months-after-delivery
#1
Won-Ho Hahn, Joon-Hwan Song, Jong-Bok Seo, Jung Eun Lee, Jeong-Sang Lee, Seunghyun Song, Joohyun Lee, Nam Mi Kang
BACKGROUND AND OBJECTIVES: Human milk has nutritional, protective, and developmental advantages for premature infants. However, proteomic information of low abundant protein of donor milk is insufficient. The purpose of this study is to analyze and compare the proteome of low abundant protein of donor milk obtained at different postpartum ages other than the colostrum. METHODS AND STUDY DESIGN: Donor breast milk from 12 healthy mothers was collected 15 days, 2 months and 6 months after delivery and stored by medically approved methods...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29220325/direction-modulation-of-muscle-synergies-in-a-hand-reaching-task
#2
Sharon Israely, Gerry Leisman, Chay Machluf, Tal Shnitzer, Eli Carmeli
Functional tasks of the upper extremity can be executed by a variety of muscular patterns, independent of the direction, speed and load of the task. This large number of degrees of freedom imposes a significant control burden on the CNS. Previous studies suggested that the human cortex synchronizes a discrete number of neural functional units within the brainstem and spinal cord, i.e. muscle synergies, by linearly combining them to execute a great repertoire of movements. Further exploring this control mechanism, we aim to study whether a single set of muscle synergies might be generalized to express movements in different directions...
December 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29216466/the-spatiotemporal-transmission-of-dengue-and-its-driving-mechanism-a-case-study-on-the-2014-dengue-outbreak-in-guangdong-china
#3
Guanghu Zhu, Jianpeng Xiao, Bing Zhang, Tao Liu, Hualiang Lin, Xing Li, Tie Song, Yonghui Zhang, Wenjun Ma, Yuantao Hao
Dengue transmission is a complex spatiotemporal process with hidden interactions between hosts, vectors, and viruses as well as environment. This study aims to identify the transmission patterns and the driving mechanism that contributed to the dengue epidemics occurred in Guangdong Province of China in 2014. Based on the city-specific epidemiological, meteorological, demographic and geographic data, we first performed wavelet analysis and then integrated the key dynamics (i.e., mosquito population dynamics, human movement, virus transmission, and parameter estimation) into a transmission model...
December 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29214039/clinical-and-genetic-analysis-of-spinocerebellar-ataxia-type-7-sca7-in-zambian-families
#4
Masharip Atadzhanov, Danielle C Smith, Mwila H Mwaba, Omar K Siddiqi, Alan Bryer, L Jacquie Greenberg
Background: To date, 43 types of Spinocerebellar Ataxias (SCAs) have been identified. A subset of the SCAs are caused by the pathogenic expansion of a CAG repeat tract within the corresponding gene. Ethnic and geographic differences are evident in the prevalence of the autosomal dominant SCAs. Few descriptions of the clinical phenotype and molecular genetics of the SCAs are available from the African continent. Established studies mostly concern the South African populations, where there is a high frequency of SCA1, SCA2 and SCA7...
2017: Cerebellum & Ataxias
https://www.readbyqxmd.com/read/29209961/finite-element-analysis-of-the-wrist-in-stroke-patients-the-effects-of-hand-grip
#5
Muhammad Hanif Ramlee, Gan Kok Beng, Nazri Bajuri, Mohammed Rafiq Abdul Kadir
The provision of the most suitable rehabilitation treatment for stroke patient remains an ongoing challenge for clinicians. Fully understanding the pathomechanics of the upper limb will allow doctors to assist patients with physiotherapy treatment that will aid in full arm recovery. A biomechanical study was therefore conducted using the finite element (FE) method. A three-dimensional (3D) model of the human wrist was reconstructed using computed tomography (CT)-scanned images. A stroke model was constructed based on pathological problems, i...
December 5, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29205379/in-vivo-measurement-of-swallowing-by-monitoring-thyroid-cartilage-movement-in-healthy-subjects-using-thickened-liquid-samples-and-its-comparison-with-sensory-evaluation
#6
Takahiro Funami, Shingo Matsuyama, Akira Ikegami, Makoto Nakauma, Kazuhiro Hori, Takahiro Ono
This research aimed to investigate the relationship between in vivo measurement of swallowing and sensory evaluation using thickened liquids as model foods. Healthy subjects (8 male and average 29.6-year old) participated in both tests, in which the subjects were asked to swallow the whole amount of sample (10 ml) at one time. In vivo measurement monitored thyroid cartilage movement during swallowing using a bendable pressure sensor synchronously with suprahyoid electromyography, whereas sensory evaluation measured perceived cohesiveness and adhesiveness on a visual analogue scale...
December 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/29205223/investigation-of-chest-injury-mechanism-caused-by-different-seatbelt-loads-in-frontal-impact
#7
Sen Xiao, Jikuang Yang, Jeff R Crandall
PURPOSE: The purpose of this quantitative study is to investigate the differences of the injury mechanism caused by two different types of seatbelt loads on the occupant's chest. METHODS: The finite element analysis is employed to compare the different responses of the human body model, including comparison of kinematics, chest accelerations, seatbelt forces and chest injury outcomes regarding chest deflections and rib fractures. RESULTS: The calculated rib strain-stress response from simulations in force-limiting seatbelt are higher than that in the regular seatbelt...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29202107/a-multi-level-spatial-analysis-of-clinical-malaria-and-subclinical-plasmodium-infections-in-pailin-province-cambodia
#8
Daniel M Parker, Rupam Tripura, Thomas J Peto, Richard J Maude, Chea Nguon, Jeremy Chalk, Pasathorn Sirithiranont, Mallika Imwong, Lorenz von Seidlein, Nicholas J White, Arjen M Dondorp
Background: The malaria burden is decreasing throughout the Greater Mekong Subregion, however transmission persists in some areas. Human movement, subclinical infections and complicated transmission patterns contribute to the persistence of malaria. This research describes the micro-geographical epidemiology of both clinical malaria and subclinical Plasmodium infections in three villages in Western Cambodia. Methods: Three villages in Western Cambodia were selected for the study based on high reported Plasmodium falciparum incidence...
November 2017: Heliyon
https://www.readbyqxmd.com/read/29197617/3-d-motion-capture-for-long-term-tracking-of-spontaneous-locomotor-behaviors-and-circadian-sleep-wake-rhythms-in-mouse
#9
Melissa Sourioux, Emma Bestaven, Etienne Guillaud, Sandrine Bertrand, Magali Cabanas, Lea Milan, Willy Mayo, Maurice Garret, Jean-René Cazalets
BACKGROUND: Locomotor activity provides an index of an animal's behavioral state. Here, we report a reliable and cost-effective method that allows long-term (days to months) simultaneous tracking of locomotion in mouse cohorts (here consisting of 24 animals). NEW METHOD: The technique is based on a motion capture system used mainly for human movement study. A reflective marker was placed on the head of each mouse using a surgical procedure and labeled animals were returned to their individual home cages...
November 29, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29196716/disrupted-superior-collicular-activity-may-reveal-cervical-dystonia-disease-pathomechanisms
#10
Eavan M Mc Govern, Owen Killian, Shruti Narasimham, Brendan Quinlivan, John B Butler, Rebecca Beck, Ines Beiser, Laura W Williams, Ronan P Killeen, Michael Farrell, Sean O'Riordan, Richard B Reilly, Michael Hutchinson
Cervical dystonia is a common neurological movement disorder characterised by muscle contractions causing abnormal movements and postures affecting the head and neck. The neural networks underpinning this condition are incompletely understood. While animal models suggest a role for the superior colliculus in its pathophysiology, this link has yet to be established in humans. The present experiment was designed to test the hypothesis that disrupted superior collicular processing is evident in affected patients and in relatives harbouring a disease-specific endophenotype (abnormal temporal discrimination)...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29196664/the-origin-of-human-handedness-and-its-role-in-pre-birth-motor-control
#11
Valentina Parma, Romain Brasselet, Stefania Zoia, Maria Bulgheroni, Umberto Castiello
The vast majority of humans are right-handed, but how and when this bias emerges during human ontogenesis is still unclear. We propose an approach that explains postnatal handedness starting from 18 gestational weeks using a kinematic analysis of different fetal arm movements recorded during ultrasonography. Based on the hand dominance reported postnatally at age 9, the fetuses were classified as right-handed (86%) or left-handed, in line with population data. We revealed that both right-handed and left-handed fetuses were faster to reach to targets requiring greater precision (i...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29191634/a-mathematical-analysis-to-address-the-6-degree-of-freedom-segmental-power-imbalance
#12
Anahid Ebrahimi, John D Collins, Thomas M Kepple, Kota Z Takahashi, Jill S Higginson, Steven J Stanhope
Segmental power is used in human movement analyses to indicate the source and net rate of energy transfer between the rigid bodies of biomechanical models. Segmental power calculations are performed using segment endpoint dynamics (kinetic method). A theoretically equivalent method is to measure the rate of change in a segment's mechanical energy state (kinematic method). However, these two methods have not produced experimentally equivalent results for segments proximal to the foot, with the difference in methods deemed the "power imbalance...
November 6, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29191554/structure-based-design-synthesis-and-binding-mode-analysis-of-novel-and-potent-chymase-inhibitors
#13
Junko Futamura-Takahashi, Taisaku Tanaka, Hajime Sugawara, Shinzo Iwashita, Seiichi Imajo, Yoshiaki Oyama, Tsuyoshi Muto
Based on insight from the X-ray crystal structure of human chymase in complex with compound 1, a lactam carbonyl of the diazepane core was exchanged with O-substituted oxyimino group, leading to amidoxime derivatives. This modification resulted in highly potent chymase inhibitors, such as O-phenylamidoxime 5f. X-ray crystal structure analysis indicated that compound 5f induced movement of the Leu99 and Tyr94 side chains at the S2 site, and the increase in inhibitory activity of O-phenyl amidoxime derivatives suggested that the O-phenyl moiety interacted with the Tyr94 residue...
November 16, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/29190785/inclusion-of-periodontal-ligament-fibres-in-mandibular-finite-element-models-leads-to-an-increase-in-alveolar-bone-strains
#14
Steven W McCormack, Ulrich Witzel, Peter J Watson, Michael J Fagan, Flora Gröning
Alveolar bone remodelling is vital for the success of dental implants and orthodontic treatments. However, the underlying biomechanical mechanisms, in particular the function of the periodontal ligament (PDL) in bone loading and remodelling, are not well understood. The PDL is a soft fibrous connective tissue that joins the tooth root to the alveolar bone and plays a critical role in the transmission of loads from the tooth to the surrounding bone. However, due to its complex structure, small size and location within the tooth socket it is difficult to study in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/29188442/categorizing-coordination-from-the-perception-of-joint-actions
#15
Joseph M Burling, Hongjing Lu
The ability to perceive others' actions and coordinate our own body movements accordingly is essential for humans to interact with the social world. However, it is still unclear how the visual system achieves the remarkable feat of identifying temporally coordinated joint actions between individuals. Specifically, do humans rely on certain visual features of coordinated movements to facilitate the detection of meaningful interactivity? To address this question, participants viewed short video sequences of two actors performing different joint actions, such as handshakes, high fives, etc...
November 29, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29187623/skill-not-athleticism-predicts-individual-variation-in-match-performance-of-soccer-players
#16
REVIEW
Robbie S Wilson, Gwendolyn K David, Sean C Murphy, Michael J Angilletta, Amanda C Niehaus, Andrew H Hunter, Michelle D Smith
Just as evolutionary biologists endeavour to link phenotypes to fitness, sport scientists try to identify traits that determine athlete success. Both disciplines would benefit from collaboration, and to illustrate this, we used an analytical approach common to evolutionary biology to isolate the phenotypes that promote success in soccer, a complex activity of humans played in nearly every modern society. Using path analysis, we quantified the relationships among morphology, balance, skill, athleticism and performance of soccer players...
December 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29181398/rheumatoid-arthritis-affecting-the-upper-cervical-spine-biomechanical-assessment-of-the-stabilizing-ligaments
#17
Carolin Meyer, Jan Bredow, Elisa Heising, Peer Eysel, Lars Peter Müller, Gregor Stein
Diameters of anterior and posterior atlantodental intervals (AADI and PADI) are diagnostically conclusive regarding ongoing neurological disorders in rheumatoid arthritis. MRI and X-ray are mostly used for patients' follow-up. This investigation aimed at analyzing these intervals during motion of cervical spine, when transverse and alar ligaments are damaged. AADI and PADI of 10 native, human cervical spines were measured using lateral fluoroscopy, while the spines were assessed in neutral position first, in maximal inclination second, and in maximal extension at last...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29170817/postmortem-1h-mrs-detection-of-ketone-bodies-and-glucose-in-diabetic-ketoacidosis
#18
Jakob Heimer, Dominic Gascho, Vasiliki Chatzaraki, Damaris Fröhlich Knaute, Vera Sterzik, Rosa Maria Martinez, Michael J Thali, Niklaus Zoelch
Diabetic ketoacidosis (DKA) is a metabolic complication of diabetes mellitus that takes a lethal course if untreated. In this way relevant to forensic medicine, secure diagnosis of DKA usually involves the evidence of elevated levels of glucose and the ketone bodies acetone, acetoacetate, and β-hydroxybutyrate in corpse fluids. We conducted a postmortem hydrogen proton magnetic resonance spectroscopy (1H-MRS) in a case of lethal DKA. Distinctive resonances of all three ketone bodies as well as glucose were visible in spectra of cerebrospinal fluid, vitreous humor, and white matter...
November 23, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29164648/a-state-transition-framework-for-patient-level-modeling-of-engagement-and-retention-in-hiv-care-using-longitudinal-cohort-data
#19
Hana Lee, Joseph W Hogan, Becky L Genberg, Xiaotian K Wu, Beverly S Musick, Ann Mwangi, Paula Braitstein
The human immunodeficiency virus (HIV) care cascade is a conceptual model used to outline the benchmarks that reflects effectiveness of HIV care in the whole HIV care continuum. The models can be used to identify barriers contributing to poor outcomes along each benchmark in the cascade such as disengagement from care or death. Recently, the HIV care cascade has been widely applied to monitor progress towards HIV prevention and care goals in an attempt to develop strategies to improve health outcomes along the care continuum...
November 22, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/29162445/the-neuromorphological-caudate-putaminal-clustering-of-neostriate-interneurons-kohonen-self-organizing-maps-and-supervised-artificial-neural-networks-with-multivariate-analysis
#20
Ivan Grbatinić, Nebojša Milošević, Bojana Krstonošić
AIMS: The objective of this study is to investigate the possibility of the neuromorphotopological clustering of neostriate interneurons (NSIN) and their consequent classification into caudate (CIN) and putaminal neuron type (PIN), according to the nuclear localization of the neurons. It tends to discover whether these two topological neuron types are morphologically different. MATERIAL AND METHODS: The binary images of adult human NSIN are used for the purposes of the analysis...
November 18, 2017: Journal of Theoretical Biology
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