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https://www.readbyqxmd.com/read/28431193/evaluation-of-cholesterol-as-a-biomarker-for-suicidality-in-a-veteran-sample
#1
Chuck Reuter, Barbara Caldwell, Heather Basehore
A reduction in total cholesterol may alter the microviscosity of the brain-cell-membrane, reducing serotonin receptor exposure. The resulting imbalance between serotonin and dopamine may lead to an increased risk for suicidality. The objective of this research was to evaluate total cholesterol as a biological marker for suicidality in a sample of US military veterans. The study population consisted of veterans who received care at the Coatesville Veterans Affairs Medical Center (VAMC) and were included in the Suicide Prevention Coordinator's database for having suicidal ideation with evidence of escalating intent, a documented suicide attempt, or committed suicide between 2009 and 2015...
April 21, 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/28429385/risk-factors-proximate-to-suicide-and-suicide-risk-assessment-in-the-context-of-denied-suicide-ideation
#2
Alan L Berman
Health care providers have significant opportunities to identify individuals at near-term risk for suicide, but lack empirical data on near-term risk factors. This study aimed to identify dynamic, state-related risk factors observed by clinical practitioners within the last 30 days of life of 157 patients who died by suicide and to compare these near-term risk factors among patients who denied versus responded positively to having suicide ideation (SI) when last asked by a clinical practitioner prior to their death...
April 21, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28428806/is-low-total-cholesterol-levels-associated-with-suicide-attempt-in-depressive-patients
#3
A Messaoud, R Mensi, A Mrad, A Mhalla, I Azizi, B Amemou, I Trabelsi, M H Grissa, N Haj Salem, A Chadly, W Douki, M F Najjar, L Gaha
BACKGROUND: Patients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increased vulnerability to suicide. In this study, we investigate the relation between lipid parameters and suicide risk in patients with MDD. METHODS: Plasma levels of total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) were determined in 160 patients meeting the DSM-IV-TR criteria for MDD (110 patients without suicidal behavior and 52 suicidal attempters) and 151 healthy controls...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28427969/hyperbaric-oxygen-therapy-is-associated-with-lower-short-and-long-term-mortality-in-patients-with-carbon-monoxide-poisoning
#4
Chien-Cheng Huang, Chung-Han Ho, Yi-Chen Chen, Hung-Jung Lin, Chien-Chin Hsu, Jhi-Joung Wang, Shih-Bin Su, How-Ran Guo
BACKGROUND: To date, there has been no consensus about the effect of hyperbaric oxygen therapy (HBOT) on the mortality of patients with carbon monoxide poisoning (COP). This retrospective nationwide population-based cohort study from Taiwan was conducted to clarify this issue. METHODS: Using the Nationwide Poisoning Database, we identified 25,737 COP patients diagnosed between 1999 and 2012, including 7,278 patients who received HBOT and 18,459 patients who did not...
April 17, 2017: Chest
https://www.readbyqxmd.com/read/28426687/does-ethnicity-matter-in-risk-and-protective-factors-for-suicide-attempts-and-suicide-lethality
#5
Carol C Choo, Keith M Harris, Peter K H Chew, Roger C Ho
This study explored ethnic differences in risk and protective factors for suicide attempts, for the major ethnic groups in Singapore, and ethnic differences in prediction of lethality. Three years of medical records related to suicide attempters (N = 666) who were admitted to the emergency department of a large teaching hospital in Singapore were subjected to analysis. Of the sample, 69.2% were female, 30.8% male; 63.8% Chinese, 15.8% Indian, and 15.0% Malay. Indians were over-represented in this sample, as compared with the ethnic distribution in the general population...
2017: PloS One
https://www.readbyqxmd.com/read/28426335/chaplaincy-encounters-following-a-suicide-attempt
#6
Marek S Kopacz, Cathleen P Kane, Wilfred R Pigeon, Jason A Nieuwsma
This descriptive study examines the provision of chaplaincy services to veterans who sought health care at a Department of Veterans Affairs (VA) Medical Center following a suicide attempt. A system-wide VA database of suicidal behavior was used to identify a cohort of n = 22,701 veterans who survived a suicide attempt. Next, an electronic review of VA clinical records found that n = 7,447 (32.8%) received chaplaincy services in the 30 days following their attempt. Of this group, the overwhelming majority of first chaplaincy encounters took place in in-patient settings: n = 6890 (92...
April 20, 2017: Journal of Health Care Chaplaincy
https://www.readbyqxmd.com/read/28424743/towards-bi-inclusive-policies-suggestions-based-on-research-on-dutch-same-sex-attracted-young-people
#7
Jantine van Lisdonk, Saskia Keuzenkamp
Dutch national LGBT policies are not bi-inclusive and this study provides suggestions for improvement, based on empirical research. Attention for bisexuality in policy appears simply to pay lip service and to endorse the construction of sexual orientation as a hetero/homo binary. The outcomes of our survey (n = 1449) and in-depth interviews (n = 38) of Dutch same-sex attracted young people suggest that special attention for bisexual people is warranted. Compared to exclusively same-sex attracted participants, the equally both-sex attracted participants scored worse on openness about their sexual attraction, visibility discomfort, perceived acceptance, and suicide attempts...
2017: Sexuality Research & Social Policy
https://www.readbyqxmd.com/read/28424378/-recognition-care-and-prevention-of-suicidal-behaviour-in-adults
#8
Zoltán Rihmer, Attila Németh, Tamás Kurimay, Dóra Perczel-Forintos, György Purebl, Péter Döme
Suicide is a major public health problem everywhere in the world and in the WHO European Region suicide accounts for over 120,000 deaths per year. 1. Recognition and diagnosis: An underlying psychiatric disorder is present in up to 90% of people who completed suicide. Comorbidity with depression, anxiety, substance abuse and personality disorders is high. In order to achieve successful prevention of suicidality, adequate diagnostic procedures and appropriate treatment for the underlying disorder are essential...
2017: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/28423132/repair-of-penetrating-pericardial-and-diaphragmatic-injury-with-cormatrix%C3%A2-patch-in-a-case-of-suicide-attempt
#9
Federica Jiritano, Carlo Garrasi, Lucia Cristodoro, Egidio Bevacqua, Pasquale Mastroroberto
The authors report the case of a suicide attempt. A 59-year-old man with self-inflicted penetrating chest trauma underwent emergency cardiothoracic surgery. Pre-operative computed tomography scan showed critical proximity between the blade and the right ventricle. Intraoperative findings showed a pericardial laceration and a huge diaphragmatic lesion with heart and abdominal organs integrity. The diaphragm muscle was repaired with a CorMatrix® patch, an acceptable alternative to the traditional synthetic mesh avoiding infection and repeated herniation...
January 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28422579/is-the-higher-number-of-suicide-attempts-in-bipolar-disorder-vs-major-depressive-disorder-attributable-to-illness-severity
#10
Matthew S Michaels, Tia Balthrop, Alejandro Pulido, M David Rudd, Thomas E Joiner
Objectives The present study represents an early-stage investigation into the phenomenon whereby those with bipolar disorder attempt suicide more frequently than those with unipolar depression, but do not tend to attempt suicide during mania. Methods Data for this study were obtained from baseline measurements collected in a randomized treatment study at a major southwestern United States military medical center. Results We demonstrated the rarity of suicide attempts during mania, the higher frequency of suicide attempts in those with bipolar disorder compared to those with depression, and the persistence of effects after accounting for severity of illness...
April 19, 2017: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/28422576/mechanisms-of-action-contributing-to-reductions-in-suicide-attempts-following-brief-cognitive-behavioral-therapy-for-military-personnel-a-test-of-the-interpersonal-psychological-theory-of-suicide
#11
Craig J Bryan, David S Wood, Alexis May, Alan L Peterson, Evelyn Wertenberger, M David Rudd
Brief cognitive behavioral therapy (BCBT) is associated with significant reductions in suicide attempts among military personnel. However, the underlying mechanisms of action contributing to reductions in suicide attempts in effective psychological treatments remain largely unknown. The present study conducted a secondary analysis of a randomized controlled trial of BCBT versus treatment as usual (TAU) to examine the mechanisms of action hypothesized by the interpersonal-psychological theory of suicide (IPT): perceived burdensomeness, thwarted belongingness, and fearlessness about death...
April 19, 2017: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/28421572/-suicidal-behaviour-among-prisoners-prevalence-and-association-with-psychological-distress-in-flemish-prisons
#12
L Favril, F Vander Laenen, K Audenaert
BACKGROUND: Internationally, the prevalence of suicidal behaviour (suicidal ideation, suicide plan and attempted suicide) is significantly elevated among prisoners compared to the community at large. AIM: To estimate the prevalence of suicidal behaviour among prisoners in the Flanders region of Belgium, to identify differences according to gender and custodial status, and to examine the association of recent suicidal ideation and suicide plan with psychological distress...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28421391/epidemiology-of-suicide-attempts-among-youth-transitioning-to-adulthood
#13
Martie P Thompson, Kevin Swartout
Suicide is the second leading cause of death for older adolescents and young adults. Although empirical literature has identified important risk factors of suicidal behavior, it is less understood if changes in risk factors correspond with changes in suicide risk. To address this knowledge gap, we assessed if there were different trajectories of suicidal behavior as youth transition into young adulthood and determined what time-varying risk factors predicted these trajectories. This study used four waves of data spanning approximately 13 years from the National Longitudinal Study of Adolescent Health...
April 18, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28420451/what-leads-to-high-antipsychotic-dosing-in-forensic-patients-with-schizophrenia
#14
Branimir Margetić, Branka Aukst Margetić, Dragutin Ivanec, Tija Žarković Palijan
Earlier findings suggest that forensic schizophrenia patients are treated with higher doses of antipsychotics. This practice-based specificity is insufficiently studied, and clinicians' motives regarding this practice remain poorly understood. In this editorial, the authors provide their data on treatment of forensic schizophrenia patients and identify characteristics of psychopathology and previous types of behaviors, including suicidal attempts, as potential reasons for the practice. They also emphasize that "these previous acts" often took place years ago, and suggest that current or recent aggression is unlikely the main reason for dosing, but rather the clinicians' intention to maintain "must remain unaggressive" condition...
April 19, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28419887/unpacking-the-impact-of-adverse-childhood-experiences-on-adult-mental-health
#15
Melissa T Merrick, Katie A Ports, Derek C Ford, Tracie O Afifi, Elizabeth T Gershoff, Andrew Grogan-Kaylor
Exposure to childhood adversity has an impact on adult mental health, increasing the risk for depression and suicide. Associations between Adverse Childhood Experiences (ACEs) and several adult mental and behavioral health outcomes are well documented in the literature, establishing the need for prevention. The current study analyzes the relationship between an expanded ACE score that includes being spanked as a child and adult mental health outcomes by examining each ACE separately to determine the contribution of each ACE...
April 15, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28418116/-what-is-the-point-of-life-an-interpretative-phenomenological-analysis-of-suicide-in-young-menwith-first-episode-psychosis
#16
Ruchika Gajwani, Michael Larkin, Chris Jackson
BACKGROUND: Lifetime risk of suicide in first-episode psychosis far exceeds the general population, with the risk of suicide persisting long after first presentation. There is strong evidence to suggest that women more frequently attempt suicide, while men are at a greater risk of completing suicide. First-hand experiential evidence is needed in order to better understand men's motives for, and struggles with, suicidality in early psychosis. METHODS: Semi-structured interviews were conducted with 7 participants...
April 18, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28416342/long-term-safety-and-tolerability-of-apremilast-in-patients-with-psoriasis-pooled-safety-analysis-for-%C3%A2-156%C3%A2-weeks-from-2-phase-3-randomized-controlled-trials-esteem-1-and-2
#17
Jeffrey Crowley, Diamant Thaçi, Pascal Joly, Ketty Peris, Kim A Papp, Joana Goncalves, Robert M Day, Rongdean Chen, Kamal Shah, Carlos Ferrándiz, Jennifer C Cather
BACKGROUND: Randomized, controlled trials demonstrated efficacy and safety of apremilast for moderate-to-severe plaque psoriasis and psoriatic arthritis. OBJECTIVE: Assess long-term safety of oral apremilast in psoriasis patients. METHODS: Safety findings are reported for 0 to ≥156 weeks from the Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis (ESTEEM) 1 and 2. RESULTS: The 0 to ≥156-week apremilast-exposure period included 1184 patients treated twice daily with apremilast 30 mg (1902...
April 14, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28416008/a-guide-to-acquired-vitamin-k-coagulophathy-diagnosis-and-treatment-the-russian-perspective
#18
REVIEW
Valery V Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V Pivnik, Alexander A Sergievich, Vladimir V Kodintsev, Ekaterina A Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M Tsatsakis, Kirill S Golokhvast
Physicians often come across with cases of vitamin K antagonists-dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagulants of indirect action or not reported administration of vitamin K antagonists due to memory impairment and/or other mental disorders, even deliberate use thereof (attempt to murder or suicide). Rodenticide-poisoning (coumarins, warfarins) via food or occupational accidents are difficult to diagnose. This article discusses different types of acquired vitamin K-dependent coagulopathy...
April 17, 2017: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28414583/improved-depressive-symptoms-in-adults-with-schizophrenia-during-a-smoking-cessation-attempt-with-varenicline-and-behavioral-therapy
#19
Corinne Cather, Susanne Hoeppner, Gladys Pachas, Sarah Pratt, Eric Achtyes, Kristina M Cieslak, A Eden Evins
OBJECTIVE: Smoking prevalence rates are elevated in individuals with schizophrenia spectrum disorders (SSD) compared with the general population, with attendant disproportionate smoking-related morbidity and mortality. Pharmacotherapies that improve abstinence rates in this population are underutilized, partly due to concerns about neuropsychiatric safety, particularly for those with comorbid depression or prior suicide attempt. Prospective assessment of the psychiatric safety profile of varenicline in those with SSD is needed...
April 17, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28414489/prospective-identification-of-adolescent-suicide-ideation-using-classification-tree-analysis-models-for-community-based-screening
#20
Ryan M Hill, Benjamin Oosterhoff, Julie B Kaplow
OBJECTIVE: Although a large number of risk markers for suicide ideation have been identified, little guidance has been provided to prospectively identify adolescents at risk for suicide ideation within community settings. The current study addressed this gap in the literature by utilizing classification tree analysis (CTA) to provide a decision-making model for screening adolescents at risk for suicide ideation. METHOD: Participants were N = 4,799 youth (Mage = 16...
April 17, 2017: Journal of Consulting and Clinical Psychology
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