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https://www.readbyqxmd.com/read/27864247/impact-of-a-pharmacist-delivered-discharge-and-follow-up-intervention-for-patients-with-acute-coronary-syndromes-in-qatar-a-study-protocol-for-a-randomised-controlled-trial
#1
Amani Zidan, Ahmed Awaisu, Nadir Kheir, Ziyad Mahfoud, Rasha Kaddoura, Sumaya AlYafei, Maguy Saffouh El Hajj
INTRODUCTION: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. Secondary cardiovascular risk reduction therapy (consisting of an aspirin, a β-blocker, an ACE inhibitor or an angiotensin II receptor blocker and a statin) is needed for all patients with ACS. Less than 80% of patients with ACS in Qatar use this combination after discharge. This study is aimed to evaluate the effectiveness of clinical pharmacist-delivered intervention at discharge and tailored follow-up postdischarge on decreasing hospital readmissions, emergency department (ED) visits and mortality among patients with ACS...
November 18, 2016: BMJ Open
https://www.readbyqxmd.com/read/27232910/heart-failure-in-patients-with-human-immunodeficiency-virus-infection-epidemiology-and-management-disparities
#2
Sadeer G Al-Kindi, Chantal ElAmm, Mahazarin Ginwalla, Emile Mehanna, Michael Zacharias, Rodolfo Benatti, Guilherme H Oliveira, Chris T Longenecker
BACKGROUND: Persons living with HIV are at a higher risk of cardiovascular disease despite effective antiretroviral therapy and dramatic reductions in AIDS-related conditions. We sought to identify the epidemiology of heart failure (HF) among persons living with HIV in the United States in an era of contemporary antiretroviral therapy. METHODS: Explorys is an electronic healthcare database that aggregates medical records from 23 healthcare systems nationwide. Using systemized nomenclature of medicine-clinical terms (SNOMED-CT), we identified adult patients (age>18), who had active records over the past year (September 2014-September 2015)...
September 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/26016193/-prescriptions-in-patients-with-coronary-artery-disease
#3
Anne-Laure Nevers, Maud Jandot, Nicolas Maillot, Yves Cottin
The management of stable coronary artery disease has evolved in recent years and is now based on the latest recommendations of the European Society of Cardiology. Drug prescription takes into account two strategic approaches: on the one hand, pharmacological treatments that improve the prognosis and on the other hand treatments to improve symptoms and/or ischemia. Improving the prognosis involves reducing as well as stabilizing coronary plaque thanks to 3 therapeutic classes: aspirin, statins and renin-angiotensin system blockers (ACE inhibitors or ARBs)...
March 2015: La Revue du Praticien
https://www.readbyqxmd.com/read/25374386/guideline-adherent-therapy-in-patients-with-acute-coronary-syndromes-the-epicor-registry-in-germany
#4
U Zeymer, H Heuer, P Schwimmbeck, S Genth-Zotz, K Wolff, C A Nienaber
BACKGROUND: Representative data on the current management of patients with acute coronary syndromes (ACS) are of high interest. The EPICOR registry aimed to prospectively collect such real-life data with particular focus on antithrombotic drug utilization and outcomes. METHODS: As part of the international prospective EPICOR registry, 29 hospitals in Germany documented 296 patients with ST-elevation myocardial infarction (STEMI)-ACS and 333 with unstable angina or non-STEMI (NSTEMI)-ACS surviving the hospital phase...
March 2015: Herz
https://www.readbyqxmd.com/read/24338543/compliance-with-pharmacological-treatment-among-patients-after-minimally-invasive-coronary-bypass-grafting
#5
Łukasz J Krzych, Małgorzata Lach, Sara Mustafa, Michał Joniec, Marcelina Niemiec, Maciej Wybraniec, Marek Cisowski, Andrzej Bochenek
BACKGROUND: We sought to evaluate patients' adherence to optimal pharmacotherapy as recommendedby the European Society of Cardiology, together with the assessment of potential clinical determinants of medical non-compliance in a large cohort of patients after endoscopic atraumatic coronary artery bypassing (EACAB). METHODS: This cross sectional study was conducted in a group of 706 individuals who underwent EACAB between April 1998 and December 2010. Data covering current pharmacological treatment with antiplatelet agents, beta-blockers (BB) (or heart rate lowering calcium channel blockers [CCB] in case of intolerance and/or poor efficacy of beta-blockade), angiotensin-converting enzyme (ACE) inhibitors (or angiotensin receptor blockers [ARB]) and statins was acquired...
2013: Cardiology Journal
https://www.readbyqxmd.com/read/24251458/stage-b-what-is-the-evidence-for-treatment-of-asymptomatic-left-ventricular-dysfunction
#6
REVIEW
Brent N Reed, Carla A Sueta
Although patients with American College of Cardiology / American Heart Association (ACC/AHA) Stage B heart failure, or asymptomatic left ventricular dysfunction (ALVD) are at high risk for developing symptomatic heart failure, few management strategies have been shown to slow disease state progression or improve long-term morbidity and mortality. Of the pharmacologic therapies utilized in patients with symptomatic disease, only angiotensin converting enzyme (ACE) inhibitors (and to a lesser extent, angiotensin receptor blockers, or ARBs) have been shown to improve clinical outcomes among patients with ALVD...
2015: Current Cardiology Reviews
https://www.readbyqxmd.com/read/23983908/short-term-effects-of-ivabradine-in-patients-with-chronic-stable-ischemic-heart-disease
#7
Hosam Zaky, Hind Elzein, Alawi A Alsheikh-Ali, Arif Al-Mulla
INTRODUCTION: Ivabradine is a novel selective If current inhibitor with anti-ischemic and antianginal activity. OBJECTIVES: To assess the effect of the selective If current inhibitor ivabradine on heart rate, angina pectoris, and functional capacity in stable patients with chronic coronary artery disease on maximally tolerated medical therapy. MATERIALS AND METHODS: Consecutive patients from the out-patient cardiology clinic with stable coronary artery disease documented by coronary angiography were included...
April 2013: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/22820715/effect-of-cardiovascular-drugs-on-cardiovascular-events-in-1599-patients-followed-in-an-academic-outpatient-cardiology-practice
#8
Hoang M Lai, Wilbert S Aronow, Anthony D Mercando, Phoenix Kalen, Harit V Desai, Kaushang Gandhi, Mala Sharma, Harshad Amin, Trung M Lai
This study investigated the effects of medical therapy on incidences of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABG) in an academic outpatient cardiology practice. Chart reviews were performed in 1599 treated patients (1138 men and 461 women), mean age 72 years. Medications investigated included the use of statins, beta blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and aspirin. The mean follow-up was 63 months during 1977-2009...
March 2014: American Journal of Therapeutics
https://www.readbyqxmd.com/read/22090216/what-has-changed-in-the-treatment-of-st-segment-elevation-myocardial-infarction-in-poland-in-2003-2009-data-from-the-polish-registry-of-acute-coronary-syndromes-pl-acs
#9
Lech Poloński, Mariusz Gąsior, Marek Gierlotka, Krzysztof Wilczek, Zbigniew Kalarus, Jacek Dubiel, Witold Rużyłło, Waldemar Banasiak, Grzegorz Opolski, Marian Zembala
BACKGROUND: A substantial progress has been made in Poland in the field of acute coronary syndromes (ACS) management over the last 10 years. AIM: To present the data from the Polish Registry of Acute Coronary Syndromes (PL-ACS) collected between 2003 and 2009. Changes in treatment strategies and outcomes in ST-segment myocardial infarction (STEMI) were analysed. METHODS: We analysed patients enrolled to the PL-ACS Registry - a nationwide multicenter, prospective observational study of consecutive patients hospitalised with ACS in Poland...
2011: Kardiologia Polska
https://www.readbyqxmd.com/read/21957774/-farim-farmakoterapie-po-infarktu-myokardu-post-myocardial-infarction-pharmacotherapy-study
#10
MULTICENTER STUDY
J Spinar, J Vítovec, L Spinarová et al.
A total of 2,500 patients with an anamnesis of myocardial infarction at least 1 month prior to inclusion in the study who visited a general practitioner or an internal medicine or cardiology specialist were examined. Through an internet-based portal, physicians entered patient data, their complaints, treatment, blood pressure, heart rate and main biochemical parameters. There were more men (1 787 vs. 713) and patients under 70 years of age (1 491 vs. 1 009) in the cohort. Eighteen percent of patients had more than one MI...
September 2011: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/21803725/-myocardial-infarction-registry-2010-experience-and-first-results-in-hungary
#11
András Jánosi, Péter Ofner, Béla Merkely, Péter Polgár, Péter Andréka, Károly Zámolyi, Róbert Gábor Kiss, János Tomcsányi, Zoltán László, András Vértes, Imre Varjú, Ferenc Juhász, János Simon, Sándor Bajkó
Authors present the methodology and first data of Hungarian Myocardial Infarction Register Pilot Study started 1st of January, 2010. The aim of the study is to collect epidemiological data on myocardial infarction, to examine the natural history of the disease and to investigate the main characteristics on patient care in the pilot area. The program is using standardized diagnostic criteria and predefined electronic data record forms (eCRF). The pilot area consists of 5 districts in the capital, and Szabolcs-Szatmár-Bereg county...
August 7, 2011: Orvosi Hetilap
https://www.readbyqxmd.com/read/21176257/-secondary-prevention-following-myocardial-infarction-may-be-improved-long-term-medication-use-according-to-practice-guidelines
#12
Mark-Jan Ploegstra, Marthe A Kampinga, Daan H Croon, Felix Zijlstra, Iwan C C van der Horst
OBJECTIVE: To determine the percentage of myocardial infarction patients in the Netherlands still using medication for secondary prevention according to current practice guidelines at the long term. DESIGN: Follow-up study of a prospective randomised clinical trial. METHOD: From 1071 myocardial infarction patients participating in a trial we obtained data on long-term medication use during follow-up. The medication was compared with the recommendations of the European Society of Cardiology for the use of statins, antithrombotics, renin-angiotensin-aldosterone system inhibitors and beta-blockers...
2010: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/20681466/-brno-register-2-post-myocardial-infarction-pharmacotherapy
#13
J Spinar, O Ludka, M Sepsi, J Schildberger, L Dusek, J Jarkovský et al.
We assessed 850 patients with a history of myocardial infarction >1 month ago who attended outpatient clinics of the Clinic of Internal Medicine and Cardiology at the Faculty Hospital Brno between 1st September 2009 and 31st December 2009. There were more men (650 vs. 200) and patients under 70 years of age (576 vs. 264) in the cohort. 87.8% of patients experienced one myocardial infarction only and the mean age at the first infarction was 59.0 years in men and 65.5 in women (p < 0.001). 75.8% of patients had been prescribed all recommended pharmacotherapeutic groups according to guidelines (RAAS blockers, beta-blockers, statins, antiagregation agents) and each group individually was used in > 90% of patients...
June 2010: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/19681467/-primary-prevention-of-cardiovascular-disease
#14
Tina Katić, Ivana Sakić, Mijo Bergovec
Cardiovascular diseases (CVD) are the leading cause of mortality in Croatia and in Europe. Primary prevention of CVD involves intervention before the onset of disease, and prevention of modifiable risk factors, i.e. cigarette smoking, hyperlipidemia, arterial hypertension, diabetes mellitus, inactivity, obesity. These risk factors are strongly associated and lead to impaired vascular endothelial function, chronic injury of endothelium, platelet activation and aggregation, atherosclerotic plaque formation, and in the end manifestation of CVD...
February 2009: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/19565445/-perioperative-management-of-chronic-medication-to-withhold-continue-or-intensify
#15
REVIEW
Giovanna Lurati Buse, Evelyne Bucher, Manfred D Seeberger, Miodrag Filipovic
All patients should undergo surgical procedures in the most stable and favourable condition with a continuation of chronic medication. Accordingly, this medication should be continued until the day before surgery in most patients. The preoperative period should be used to evaluate the completeness and quality of the medical treatment. Are all patient with cardiological indications for beta-receptor blocking agents, ACE-inhibitors and statins treated with these drugs? Is diabetes being adequately treated? Are the doses of the medication for the treatment of thyroid dysfunction within the optimal range? If there is room for improvement, adjustments should be done cautiously and well in advance...
July 2009: Therapeutische Umschau. Revue Thérapeutique
https://www.readbyqxmd.com/read/19214406/-esc-easd-joint-guidelines-on-diabetes-and-cardiovascular-diseases
#16
Wolfgang Motz, Rolf Dörr, et al.
The ESC/EASD (European Society of Cardiology/European Association for the Study of Diabetes) joint Guidelines on diabetes, pre-diabetes, and cardiovascular diseases have, for the first time, addressed diabetes mellitus and cardiovascular diseases (CVD) as a pathophysiological entity in Europe. Based on these guidelines, diabetes mellitus is regarded from the outset to be a cardiovascular disease, whose life-threatening complications myocardial infarction and stroke can only be avoided by an interdisciplinary concerted action...
February 2009: Herz
https://www.readbyqxmd.com/read/19214404/cardiovascular-prevention-in-clinical-practice-esc-and-german-guidelines-2007
#17
Helmut Gohlke, Christian Albus, Detlef Bernd Gysan, Harry W Hahmann, Peter Mathes et al.
Preventive efforts should be guided by the patient's global cardiovascular (CV) risk. A risk stratification should be done in every person > age 35 with more than a single risk factor. Recommendations for improved lifestyle are applicable to all persons with CV risk factors: smoking cessation, daily exercise, normal body mass index, Mediterranean diet, blood pressure < 140 mmHg systolic, and LDL cholesterol < 130 mg/dl are beneficial. If the 10-year risk is > or = 20% for CV events or > or = 5% for CV death, additional drug interventions are usually necessary: acetylsalicylic acid 100 mg daily, statins to lower LDL cholesterol to < 100 mg/dl or, in diabetics with coronary artery disease, to < 70 mg/dl, blood pressure should be < 130 mmHg systolic, e...
February 2009: Herz
https://www.readbyqxmd.com/read/19069375/unstable-angina-and-non-st-elevation-acute-coronary-syndromes
#18
Jorge Ortega-Gil, José M Pérez-Cardona
Acute coronary syndromes (ACSs) are the most common cause of hospital admission in patients with coronary artery disease (CAD). The term ACS refers to a spectrum of acute life-threatening disorders that includes: unstable angina (UA), non ST elevation myocardial infarction (NSTEMI) and ST elevation myocardial infarction (STEMI). The pathophysiology is similar: coronary atherosclerosis plaque rupture and subsequent thrombus formation. Such plaques usually are lesions with <50% stenosis severity prior to ACS, but are lipid-rich soft plaques (vulnerable plaques)...
December 2008: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/19040564/cost-effectiveness-of-treatments-reducing-coronary-heart-disease-mortality-in-ireland-2000-to-2010
#19
Kathleen Bennett, Zubair Kabir, Michael Barry, Lesley Tilson, Dogan Fidan, Emer Shelley, Simon Capewell
OBJECTIVE: Coronary heart disease (CHD) is associated with a large burden of disease in Ireland and is responsible for more than 6000 deaths annually. This study examined the cost-effectiveness of specific CHD treatments in Ireland. METHODS: Irish epidemiological data on patient numbers and median survival in specific groups, plus the uptake, effectiveness, and costs of specific interventions, all stratified by age and sex, were incorporated into a previously validated CHD mortality model, the IMPACT model...
January 2009: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/18839682/-management-of-the-patient-with-chronic-coronary-artery-disease
#20
Albert-Alain Hagège
All patients with suspected angina need rapidly further cardiological examinations to check the diagnosis and fix the prognosis (at least clinical and risk factor evaluations and a resting ECG). The initial non-invasive strategy should include an echocardiography and a stress test (exercise ECG, stress echocardiography or perfusion scintigraphy), followed, in the majority of cases, by a coronary angiography. Lifestyle changes are mandatory and are fully part of secondary prevention: cigarette smoking withdrawal, mediterranean diet (fruit, vegetables, fish and poultry), weight loss, moderate alcohol consumption, increased omega-3 fatty acids and regular physical activity...
September 30, 2008: La Revue du Praticien
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