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https://www.readbyqxmd.com/read/27886354/a-retrospective-analysis-of-the-merits-and-challenges-associated-with-simultaneous-bilateral-tha-using-the-direct-anterior-approach
#1
Matthew L Brown, Johannes F Plate, David C Holst, Daniel N Bracey, Matthew W Bullock, Jason E Lang
INTRODUCTION: 15%-20% of patients presenting for total hip arthroplasty (THA) have bilateral disease. While simultaneous bilateral THA is of interest to patients and surgeons, debate persists regarding its merits. The majority of previous reports on simultaneous bilateral THA involve patients in the lateral decubitus position, which require repositioning, prepping and draping, and exposure of a fresh wound to pressure and manipulation for the contralateral THA. The purpose of this study was to compare complications, component position, and financial parameters for simultaneous versus staged bilateral THAs using the direct anterior approach (DAA)...
November 14, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27885658/early-skin-to-skin-contact-for-mothers-and-their-healthy-newborn-infants
#2
REVIEW
Elizabeth R Moore, Nils Bergman, Gene C Anderson, Nancy Medley
BACKGROUND: Mother-infant separation post birth is common. In standard hospital care, newborn infants are held wrapped or dressed in their mother's arms, placed in open cribs or under radiant warmers. Skin-to-skin contact (SSC) begins ideally at birth and should last continually until the end of the first breastfeeding. SSC involves placing the dried, naked baby prone on the mother's bare chest, often covered with a warm blanket. According to mammalian neuroscience, the intimate contact inherent in this place (habitat) evokes neuro-behaviors ensuring fulfillment of basic biological needs...
November 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27884959/cardiac-responses-to-exercise-distinguish-postural-orthostatic-tachycardia-syndrome-variants
#3
Paolo T Pianosi, Darrell R Schroeder, Philip R Fischer
We previously showed that one-third of adolescents with postural orthostatic tachycardia syndrome (POTS) have hyperkinetic circulation. In a subsequent cohort, we compare participants with POTS grouped according to cardiac output (Q˙) versus oxygen uptake (V˙O2) function, whose circulatory response to exercise lay at the lower end of this distribution. We hypothesized that such grouping determines the circulatory response to incremental-protocol, upright, cycle ergometry by whatever blend of flow and resistance adjustments best maintains normal blood pressure...
November 2016: Physiological Reports
https://www.readbyqxmd.com/read/27879532/myocardial-protection-and-financial-considerations-of-custodiol-cardioplegia-in-minimally-invasive-and-open-valve-surgery
#4
Brian W Hummel, Randall W Buss, Paul L DiGiorgi, Brittany N Laviano, Nalani A Yaeger, M Lee Lucas, George M Comas
OBJECTIVE: Single-dose antegrade crystalloid cardioplegia with Custodiol-HTK (histidine-tryptophan-ketoglutarate) has been used for many years. Its safety and efficacy were established in experimental and clinical studies. It is beneficial in complex valve surgery because it provides a long period of myocardial protection with a single dose. Thus, valve procedures (minimally invasive or open) can be performed with limited interruption. The aim of this study is to compare the use of Custodiol-HTK cardioplegia with traditional blood cardioplegia in patients undergoing minimally invasive and open valve surgery...
November 22, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27878331/fluoroscopy-versus-ultrasound-for-image-guidance-during-percutaneous-nephrolithotomy-a-systematic-review-and-meta-analysis
#5
REVIEW
Qiang Liu, Liang Zhou, Xiang Cai, Tao Jin, Kunjie Wang
This meta-analysis aims to compare the safety and efficacy of fluoroscopy versus ultrasound guidance during the access to the renal collecting system. A systematic literature review was performed in September 2016. Outcomes were explored using review manager v5.0. 18 studies with 2919 patients were included in the final analysis. There was no significant difference in stone-free rate (RR: 1.0; 95% CI, 0.98 to 1.05; p = 0.41), operation time (MD: 1.75; 95% CI, -9.15 to 12.65; p = 0.75), hospital stay (MD: -1...
November 22, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27865687/scoring-system-to-predict-hemorrhage-in-pelvic-ring-fracture
#6
T Ohmori, T Matsumoto, T Kitamura, R Tamura, K Tada, T Inoue, T Hayashi, K Numoto, T Tokioka
BACKGROUND: Risk factors for hemorrhage in patients with pelvic ring fracture have been widely reported. Because there are many risk factors, it is thought that prediction accuracy of hemorrhage in cases of pelvic ring fracture could be improved by using a scoring system. HYPOTHESIS: We investigated the risk factors for massive hemorrhage (MH) and created a novel predictive score of MH in pelvic ring fractures. MATERIAL AND METHODS: We retrospectively reviewed patients with pelvic ring fractures (Abbreviated Injury Score≥3 and age≥16 years) from January 2007 to June 2015...
November 16, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27863764/diagnosis-and-treatment-of-chronic-lymphocytic-leukemia-recommendations-from-the-brazilian-group-of-chronic-lymphocytic-leukemia
#7
Celso Arrais Rodrigues, Matheus Vescovi Gonçalves, Maura Rosane Valério Ikoma, Irene Lorand-Metze, André Domingues Pereira, Danielle Leão Cordeiro de Farias, Maria de Lourdes Lopes Ferrari Chauffaille, Rony Schaffel, Eduardo Flávio Oliveira Ribeiro, Talita Silveira da Rocha, Valeria Buccheri, Yuri Vasconcelos, Vera Lúcia de Piratininga Figueiredo, Carlos Sérgio Chiattone, Mihoko Yamamoto
Chronic lymphocytic leukemia is characterized by clonal proliferation and progressive accumulation of B-cell lymphocytes that typically express CD19(+), CD5(+) and CD23(+). The lymphocytes usually infiltrate the bone marrow, peripheral blood, lymph nodes, and spleen. The diagnosis is established by immunophenotyping circulating B-lymphocytes, and prognosis is defined by two staging systems (Rai and Binet) established by physical examination and blood counts, as well as by several biological and genetic markers...
October 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27863762/structural-diversity-and-biological-importance-of-abo-h-lewis-and-secretor-histo-blood-group-carbohydrates
#8
Luiz Carlos de Mattos
ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine...
October 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27862491/alarmins-and-central-nervous-system-inflammation-in-hiv-associated-neurological-disorders
#9
M-L Gougeon
In the era of highly active antiretroviral therapy (HAART), HIV-1-associated neurocognitive disorders (HAND) persist in infected individuals with adequate immunological and virological status. Risk factors for cognitive impairment include hepatitis C virus co-infection, host genetic factors predisposing to HAND, the early establishment of the virus in the CNS and its persistence under HAART; thus, the CNS is an important reservoir for HIV. Microglial cells are permissive to HIV-1, and NLRP3 inflammasome-associated genes were found expressed in brains of HIV-1-infected persons, contributing to brain disease...
November 16, 2016: Journal of Internal Medicine
https://www.readbyqxmd.com/read/27843208/immunotherapy-in-metastatic-prostate-cancer
#10
REVIEW
Susan F Slovin
INTRODUCTION: Prostate cancer remains a challenge as a target for immunological approaches. The approval of the first cell-based immune therapy, Sipuleucel-T for prostate cancer introduced prostate cancer as a solid tumor with the potential to be influenced by the immune system. METHODS: We reviewed articles on immunological management of prostate cancer and challenges that lie ahead for such strategies. RESULTS: Treatments have focused on the identification of novel cell surface antigens thought to be unique to prostate cancer...
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27832362/is-reduction-better-than-arthrodesis-in-situ-in-surgical-management-of-low-grade-spondylolisthesis-a-system-review-and-meta-analysis
#11
REVIEW
Xuedong Bai, Jiahai Chen, Liyang Liu, Xiaochuan Li, Yaohong Wu, Deli Wang, Dike Ruan
PURPOSE: To compare the clinical and radiographic outcomes of arthrodesis in situ with arthrodesis after reduction in low-grade spondylolisthesis. METHODS: We performed a comprehensive search of both observational and randomized clinical trials published up to April 2016 in PubMed, MEDLINE, Cochrane Library, and Embase databases. The outcomes included age, sex, operative time, blood loss, and at least 2 years clinical results of Oswestry disability index (ODI), visual analogue scale (VAS), lumbar lordosis, slippage, fusion rate, the rate of good and excellent and the complication rate...
November 10, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27830886/anomalous-left-brachiocephalic-vein-important-vascular-anomaly-concomitant-with-congenital-anomalies-and-heart-diseases
#12
Shahram Kahkouee, Makan Sadr, Elham Pedarzadeh, Sara Fardin, Ali Borhani, Saeid Gholami, Ghazaleh Amjad
BACKGROUND: Anomalous left brachiocephalic vein (ALBCV) is a rare and less known systemic venous anomaly. Infrequently, this vein takes an abnormal course and passes to the right behind or beneath the aortic arch to create the superior vena cava (SVC). Its incidence was reported much higher in patients with congenital heart disease (CHD) especially in conotruncal and aortic arch anomalies. It could be misdiagnosed with normal or abnormal mediastinal structures. It also could make complication during surgeries or invasive strategies...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27821999/early-results-of-the-lps%C3%A2-limb-preservation-system-in-the-management-of-periprosthetic-femoral-fractures
#13
M Curtin, C Bryan, E Murphy, C G Murphy, W Curtin
INTRODUCTION: Achieving skeletal fixation in the presence of progressive bone loss is a surgical challenge, especially in cases of periprosthetic fracture (PPF). Unpredictable fracture patterns and preexisting bone loss frequently combine in this patient group. Megaprosthetic arthroplasty allows for immediate mobilisation and shorter periods of rehabilitation. We describe the clinical outcomes of a cohort of LPS™ megaprostheses performed for PPF by a single surgeon at our institution...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27810335/establishing-a-dose-response-relationship-between-acute-resistance-exercise-and-the-immune-system-protocol-for-a-systematic-review
#14
REVIEW
Adam Michael Szlezak, Siri Lauluten Szlezak, James Keane, Lotti Tajouri, Clare Minahan
Exercise immunology research has traditionally focussed on aerobic-exercise, however it has become apparent in more recent years that resistance-exercise can also considerably affect host immunobiology. To date however, no systematic process has been used to establish a dose-response relationship between resistance-exercise and the immune system. The present systematic review was thus conducted to determine the dose-response effects of a bout of resistance-exercise on acute leukocyte counts. In accordance with the PRISMA guidelines, a systematic literature search was conducted in the electronic databases, PubMed, Web of Science, and Google Scholar, over the date range of 1989-2016...
November 1, 2016: Immunology Letters
https://www.readbyqxmd.com/read/27806209/the-effectiveness-of-bariatric-surgery-for-chinese-obesity-in-2%C3%A2-years-a-meta-analysis-and-systematic-review
#15
Tianshu Zeng, Yuli Cai, Lulu Chen
AIM: Bariatric surgery is becoming an acceptable option for treatment of obesity worldwide, but there is no systemic review and meta-analysis focusing on obese patients in China. This study is to quantify the overall effects of bariatric surgery for Chinese obesity using up-to-date, comprehensive data. METHODS: We systematically searched MEDLINE, EMBASE, Cochrane Library, ISI Web of Science, and CNKI databases in English and Chinese. The weighted mean difference (MD) and 95% confidence interval (CI) were calculated from the original literature...
November 2, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27798538/compartment-syndrome-secondary-to-group-a-streptococcus-infection-in-the-presence-of-a-congenital-hemangioma
#16
Sharon L Kracoff
OBJECTIVES: Nontraumatic compartment syndrome is frequently difficult to diagnose but this is especially troublesome in infants. Pain is the most sensitive sign and is characteristically severe and refractory to routine analgesia. Failure to diagnose and treat can lead to disability, multiorgan failure, and death. Surgical intervention is crucial and includes emergent fasciotomy, debridement, nerve decompression, and later skin grafting. Streptococcal myositis causing compartment syndrome is more likely in the immunocompromised patient...
October 28, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27798002/-omics-biomarkers-associated-with-chronic-low-back-pain-protocol-of-a-retrospective-longitudinal-study
#17
Massimo Allegri, Manuela De Gregori, Cristina E Minella, Catherine Klersy, Wei Wang, Moira Sim, Christian Gieger, Judith Manz, Iain K Pemberton, Jane MacDougall, Frances Mk Williams, Jan Van Zundert, Klaas Buyse, Gordan Lauc, Ivan Gudelj, Dragan Primorac, Andrea Skelin, Yurii S Aulchenko, Lennart C Karssen, Leonardo Kapural, Richard Rauck, Guido Fanelli
INTRODUCTION: Chronic low back pain (CLBP) produces considerable direct costs as well as indirect burdens for society, industry and health systems. CLBP is characterised by heterogeneity, inclusion of several pain syndromes, different underlying molecular pathologies and interaction with psychosocial factors that leads to a range of clinical manifestations. There is still much to understand in the underlying pathological processes and the non-psychosocial factors which account for differences in outcomes...
October 19, 2016: BMJ Open
https://www.readbyqxmd.com/read/27795335/cost-analysis-of-implementing-maldi-tof-plus-real-time-antimicrobial-stewardship-intervention-for-bloodstream-infections
#18
Twisha S Patel, Rola Kaakeh, Jerod L Nagel, Duane W Newton, James G Stevenson
BACKGROUND: Studies evaluating rapid diagnostic testing plus stewardship intervention have consistently demonstrated improved clinical outcomes for patients with bloodstream infections. However, the cost of implementing new rapid diagnostic testing can be significant, and usually does not generate additional revenue. There is minimal data evaluating the financial impact of adding MALDI-TOF for rapid organism identification and dedicating pharmacy stewardship personnel time, on the total hospital costs...
October 19, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27777044/renin-angiotensin-aldosterone-system-inhibitors-in-hypertension-is-there-evidence-for-benefit-independent-of-blood-pressure-reduction
#19
Chirag Bavishi, Sripal Bangalore, Franz H Messerli
The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the pathogenesis of hypertension (HTN). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are first line anti-HTN drug classes that are potent, effective and largely safe. Direct renin inhibitors (DRIs) have shown similar blood pressure (BP) reduction but more side effects. The efficacy of ACEIs and ARBs (for cardiovascular, cerebrovascular and renal protection) has been promoted to extend beyond what could be explained by BP reduction alone...
October 21, 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27773801/a-review-of-ethnobotany-therapeutic-value-phytochemistry-and-pharmacology-of-crinum-macowanii-baker-a-highly-traded-bulbous-plant-in-southern-africa
#20
Alfred Maroyi
ETHNOPHARMACOLOGICAL RELEVANCE: Crinum macowanii is a deciduous bulbous plant which grows in east, central and southern Africa. Crinum macowanii has been used as herbal medicine by the indigenous people of east and southern Africa has for several centuries. The bulb, leaves and roots of C. macowanii are reported to possess diverse medicinal properties and used to treat or manage various human and animal diseases and ailments throughout its distributional range. Crinum macowanii is used traditionally as a remedy for boils, diarrhoea, fever, inflammation, respiratory system problems, skin rashes, tuberculosis, wounds and urinary tract problems...
October 20, 2016: Journal of Ethnopharmacology
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