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https://www.readbyqxmd.com/read/28102954/dosimetric-impact-of-lipiodol-in-stereotactic-body-radiation-therapy-on-liver-after-trans-arterial-chemoembolization
#1
Daisuke Kawahara, Shuichi Ozawa, Akito Saito, Teiji Nishio, Tomoki Kimura, Tatsuhiko Suzuki, Kazunari Hioki, Takeo Nakashima, Yoshimi Ohno, Yuji Murakami, Yasushi Nagata
PURPOSE: Stereotactic body radiation therapy (SBRT) combining trans-arterial chemoembolization (TACE) with Lipiodol is expected to improve local control. This study is aimed to estimate the dose enhancement in Lipiodol's proximity and to evaluate the dose calculation accuracy of the Acuros XB (AXB) algorithm and anisotropic analytical algorithm (AAA) in the Eclipse treatment planning system (TPS) (ver. 11, Varian Medical Systems, Palo Alto, USA), compared with that of the Monte Carlo (MC) calculation (using BEAMnrc/DOSXYZnrc code) for a virtual phantom and a treatment plan for liver SBRT after TACE...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28048803/su-f-t-152-experimental-validation-and-calculation-benchmark-for-a-commercial-monte-carlo-pencil-beamscanning-proton-therapy-treatment-planning-system-in-heterogeneous-media
#2
L Lin, S Huang, M Kang, C Ainsley, C Simone, J McDonough, T Solberg
PURPOSE: Eclipse AcurosPT 13.7, the first commercial Monte Carlo pencil beam scanning (PBS) proton therapy treatment planning system (TPS), was experimentally validated for an IBA dedicated PBS nozzle in the CIRS 002LFC thoracic phantom. METHODS: A two-stage procedure involving the use of TOPAS 1.3 simulations was performed. First, Geant4-based TOPAS simulations in this phantom were experimentally validated for single and multi-spot profiles at several depths for 100, 115, 150, 180, 210 and 225 MeV proton beams, using the combination of a Lynx scintillation detector and a MatriXXPT ionization chamber array...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048714/su-f-t-137-out-of-beam-dose-for-a-compact-double-scattering-proton-beam-therapy-system
#3
M Islam, S Ahmad, H Jin
PURPOSE: The out-of-beam dose is important for understanding the peripheral dose in radiation therapy. In proton radiotherapy, the study of out-of-beam dose is scarce and the treatment planning system (TPS) based on pencil beam algorithm cannot accurately predict the out-of-beam dose. This study investigates the out-of-beam dose for the single-room Mevion S250 double scattering proton therapy system using experimentally measured and treatment planning software generated data. The results are compared with those reported for conventional photon beam therapy...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048684/su-f-t-115-uncertainty-in-the-esophagus-dose-in-retrospective-epidemiological-study-of-breast-cancer-radiotherapy-patients
#4
E Mosher, S Kim, C Lee, C Pelletier, J Jung, E Jones, C Lee
PURPOSE: Epidemiological studies of second cancer risks in breast cancer radiotherapy patients often use generic patient anatomy to reconstruct normal tissue doses when CT images of patients are not available. To evaluate the uncertainty involved in the dosimetry approach, we evaluated the esophagus dose in five sample patients by simulating breast cancer treatments. METHODS: We obtained the diagnostic CT images of five anonymized adult female patients in different Body Mass Index (BMI) categories (16- 36kg/m2) from National Institutes of Health Clinical Center...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048673/su-f-t-288-impact-of-trajectory-log-files-for-clarkson-based-independent-dose-verification-of-imrt-and-vmat
#5
R Takahashi, T Kamima, H Tachibana
PURPOSE: To investigate the effect of the trajectory files from linear accelerator for Clarkson-based independent dose verification in IMRT and VMAT plans. METHODS: A CT-based independent dose verification software (Simple MU Analysis: SMU, Triangle Products, Japan) with a Clarksonbased algorithm was modified to calculate dose using the trajectory log files. Eclipse with the three techniques of step and shoot (SS), sliding window (SW) and Rapid Arc (RA) was used as treatment planning system (TPS)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048645/su-f-t-404-dosimetric-advantages-of-flattening-free-beams-to-prone-accelerated-partial-breast-irradiation
#6
P Galavis, D Barbee, G Jozsef
PURPOSE: Prone accelerated partial breast irradiation (APBI) results in dose reduction to the heart and lung. Flattening filter free beams (FFF) reduce out of field dose due to the reduced scatter from the removal of the flattening filter and reduce the buildup region. The aim of this work is to evaluate the dosimetric advantages of FFF beams to prone APBI target coverage and reduction in dose to organs at risk. METHODS: Fifteen clinical prone APBI cases using flattened photon beams were retrospectively re-planned in Eclipse-TPS using FFF beams...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048620/su-f-t-308-mobius-fx-evaluation-and-comparison-against-a-commercial-4d-detector-array-for-vmat-plan-qa
#7
L Vazquez Quino, C Huerta Hernandez, A Morrow, B Massingill, D Rangaraj
PURPOSE: To evaluate the use of MobiusFX as a pre-treatment verification IMRT QA tool and compare it with a commercial 4D detector array for VMAT plan QA. METHODS: 15 VMAT plan QA of different treatment sites were delivered and measured by traditional means with the 4D detector array ArcCheck (Sun Nuclear corporation) and at the same time measurement in linac treatment logs (Varian Dynalogs files) were analyzed from the same delivery with MobiusFX software (Mobius Medical Systems)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048571/su-f-t-280-an-assessment-of-deviations-in-gamma-index-between-ptw-octavius4d-phantom-measurements-and-various-treatment-planning-systems
#8
J E Roring, A Alexandrian, N Papanikolaou, S Stathakis
PURPOSE: There is a variety of treatment planning systems (TPS) available for clinical use all with highly variable settings to calculate patient dose. Patient specific IMRT QA is often a daily procedure at most clinics and each clinic devises their own policy on the TPS settings for testing the quality of the patient plan against a measured dose on IMRT QA phantoms. With this in mind, it is the aim of this study to evaluate the effect of dose calculation parameters on IMRT QA. METHODS: Six patient plans were optimized and calculated using Pinnacle(3) (v9...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048481/su-f-t-562-validation-of-epid-based-dosimetry-for-fsrs-commissioning
#9
Y Song, Z Saleh, C Obcemea, M Chan, X Tang, S Lim, D Lovelock, A Ballangrud, B Mueller, M Zinovoy, D Gelblum, B Mychalczak, S Both
PURPOSE: The prevailing approach to frameless SRS (fSRS) small field dosimetry is Gafchromic film. Though providing continuous information, its intrinsic uncertainties in fabrication, response, scan, and calibration often make film dosimetry subject to different interpretations. In this study, we explored the feasibility of using EPID portal dosimetry as a viable alternative to film for small field dosimetry. METHODS: Plans prescribed a dose of 21 Gy were created on a flat solid water phantom with Eclipse V11 and iPlan for small static square fields (1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048475/su-f-t-522-dosimetric-study-of-junction-dose-in-double-isocenter-flatten-and-flatten-filter-free-imrt-and-vmat-plan-delivery
#10
K Samuvel, G Yadav, M Bhushan, S Tamilarasu, L Kumar, M Suhail
PURPOSE: To quantify the dosimetric accuracy of junction dose in double isocenter flattened and flatten filter free(FFF) intensity modulated radiation therapy(IMRT) and volumetric modulated arc therapy(VMAT) plan delivery using pelvis phantom. METHODS: Five large field pelvis patients were selected for this study. Double isocenter IMRT and VMAT treatment plans were generated in Eclipse Treatment planning System (V.11.0) using 6MV FB and FFF beams. For all the plans same distance 17...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048453/su-f-t-437-3-field-vmat-technique-for-irradiation-of-large-pelvic-tumors
#11
V Stakhursky
PURPOSE: VMAT treatment planning for large pelvic volume irradiation could be suboptimal due to inability of Varian linac to split MLC carriage during VMAT delivery for fields larger than 14.5cm in X direction (direction of leaf motion). We compare the dosimetry between 3 VMAT planning techniques, two 2-arc field techniques and a 3-arc field technique: a) two small in X direction (less than 14.5cm) arc fields, complementing each other to cover the whole lateral extent of target during gantry rotation, b) two large arc fields, each covering the targets completely during the rotation, c) a 3 field technique with 2 small in X direction arcs and 1 large field covering whole target...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048326/su-g-tep4-02-a-method-for-evaluating-the-direct-impact-of-failed-imrt-qas-on-patient-dose
#12
S Geneser, M Butkus
PURPOSE: We developed a method to calculate patient doses corresponding to IMRT QA measurements in order to determine and assess the actual dose delivered for plans with failed (or borderline) IMRT QA. This work demonstrates the feasibility of automatically computing delivered patient dose from portal dosimetry measurements in the Varian TPS system, which would provide a valuable and clinically viable IMRT QA tool for physicists and physicians. METHODS: IMRT QA fluences were measured using portal dosimetry, processed using in-house matlab software, and imported back into Eclipse to calculate dose on the planning CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048260/su-f-p-37-implementation-of-an-end-to-end-qa-test-of-the-radiation-therapy-imaging-planning-and-delivery-process-to-identify-and-correct-possible-sources-of-deviation
#13
F Salinas Aranda, V Suarez, S Arbiser, R Sansogne
PURPOSE: To implement an end-to-end QA test of the radiation therapy imaging, planning and delivery process, aimed to assess the dosimetric agreement accuracy between planned and delivered treatment, in order to identify and correct possible sources of deviation. To establish an internal standard for machine commissioning acceptance. METHODS: A test involving all steps of the radiation therapy: imaging, planning and delivery process was designed. The test includes analysis of point dose and planar dose distributions agreement between TPS calculated and measured dose...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048205/th-d-brb-02-eclipse-scripting-fundamentals-in-net
#14
R Cardan
: Scripting capabilities and application programming interfaces (APIs) are becoming commonly available in modern treatment planning systems. These links to the treatment planning system (TPS) allow users to read data from the TPS, and in some cases use TPS functionality and write data back to the TPS. Such tools are powerful extensions, allowing automation of routine clinical tasks and supporting research, particularly research involving repetitive tasks on large patient populations. The data and functionality exposed by scripting/API capabilities is vendor dependent, as are the languages used by script/API engines, such as the Microsoft ...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048089/su-f-t-160-commissioning-of-a-single-room-double-scattering-proton-therapy-system
#15
H Jin, S Ahmad, Y Chen, V Keeling, A Lau, M Islam, C Ferreira, S Ferguson
PURPOSE: To report the detailed commissioning experience for a compact double-scattering Mevion S250 proton therapy system at a University Cancer Center site. METHODS: The commissioning of the proton therapy system mainly consisted of ensuring integrity of mechanical and imaging system, beam data collection, and commissioning of a treatment planning system (TPS). First, mechanical alignment and imaging were tested including safety, interlocks, positional accuracy of couch and gantry, image quality, mechanical and imaging isocenter and so on...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048010/su-f-t-216-evaluating-dosimetry-accuracy-of-a-treatment-planning-system-on-small-proton-fields
#16
M Zhang, Z Xiao, J Zou, T Chen, N Yue
PURPOSE: This study is aiming to identify the smallest field size for which a treatment planning system (TPS) can accurately calculate the relative dose distribution. The finding would be used as a guideline to choose the smallest proton field for clinical treatment. METHODS: Mevion S250™ double scattering proton delivery system and Eclipse™ TPS (Varian) with pencil beam convolution (PBC) dose algorithm were used in this study. Square sized fields of 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, and 10 cm were planned on a cubical water phantom with iso-center placed at 10 cm depth...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047964/su-f-t-354-evaluation-of-new-features-of-two-commercial-automated-treatment-planning-systems
#17
X Han, W Hu, X Chen
PURPOSE: To evaluate the individual and combined performance of Auto-Planning and RapidPlan for IMRT plans applied to locally advanced cervical cancer. METHODS: A cohort of 10 patients previously treated with IMRT technique were selected for this study. 10 plans (AP) were generated with Pinnacle version 9.10 based on on single template, and only one optimization cycle was allowed for each plan. 10 sets of patient specific DVH prediction were generated with RapidPlan (Eclipse 13...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047952/su-f-t-240-epid-based-quality-assurance-for-dosimetric-credentialing
#18
N Miri, J Lehmann, P Vial, P Greer
PURPOSE: We propose a novel dosimetric audit method for clinical trials using EPID measurements at each center and a standardized EPID to dose conversion algorithm. The aim of this work is to investigate the applicability of the EPID method to different linear accelerator, EPID and treatment planning system (TPS) combinations. METHODS: Combination of delivery and planning systems were three Varian linacs including one Pinnacle and two Eclipse TPS and, two ELEKTA linacs including one Pinnacle and one Monaco TPS...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047904/su-f-t-305-clinical-effects-of-dosimetric-leaf-gap-dlg-values-between-matched-varian-truebeam-tb-linacs
#19
D Mihailidis, J Mallah, D Zhu
PURPOSE: The dosimetric leaf gap (DLG) is an important parameter to be measured for dynamic beam delivery of modern linacs, like the Varian Truebeam (TB). The clinical effects of DLG-values on IMRT and/or VMAT commissioning of two "matched" TB linacs will be presented. METHODS AND MATERIALS: The DLG values on two TB linacs were measured for all energy modalities (filtered and FFF-modes) as part of the dynamic delivery mode commissioning (IMRT and/or VMAT. After the standard beam data was modeled in eclipse treatment planning system (TPS) and validated, IMRT validation was performed based on TG1191 benchmark, IROC Head-Neck (H&N) phantom and sample of clinical cases, all measured on both linacs...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047864/su-f-t-431-dosimetric-validation-of-acuros-xb-algorithm-for-photon-dose-calculation-in-water
#20
L Kumar, G Yadav, V Kishore, M Bhushan, K Samuvel, M Suhail
PURPOSE: To validate the Acuros XB algorithm implemented in Eclipse Treatment planning system version 11 (Varian Medical System, Inc., Palo Alto, CA, USA) for photon dose calculation. METHODS: Acuros XB is a Linear Boltzmann transport equation (LBTE) solver that solves LBTE equation explicitly and gives result equivalent to Monte Carlo. 6MV photon beam from Varian Clinac-iX (2300CD) was used for dosimetric validation of Acuros XB. Percentage depth dose (PDD) and profiles (at dmax, 5, 10, 20 and 30 cm) measurements were performed in water for field size ranging from 2×2,4×4, 6×6, 10×10, 20×20, 30×30 and 40×40 cm(2) ...
June 2016: Medical Physics
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