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Yvan Vandenplas, Rajat Mukherjee, Christophe Dupont, Philippe Eigenmann, Arne Høst, Mikael Kuitunen, Carmen Ribes-Koninkx, Neil Shah, Hania Szajewska, Andrea von Berg, Ralf G Heine, Zheng-Yan Zhao
INTRODUCTION: The symptoms of cow's milk protein allergy (CMPA) in infancy can be non-specific which may delay a correct diagnosis and cause adverse clinical outcomes. The diagnosis of non-IgE-mediated CMPA is particularly complex as it involves a 2 to 4 week elimination diet followed by oral food challenge (OFC). The Cow's Milk-related Symptom Score (CoMiSS) is a clinical resource for primary healthcare providers which aims to increase awareness of CMPA symptoms to facilitate an earlier diagnosis...
May 17, 2018: BMJ Open
Niall Gilliland, Natalie Catherwood, Shaouyn Chen, Peter Browne, Jacob Wilson, Helena Burden
Introduction and aims: Concerns had been raised at clinical governance regarding the safety of our inpatient ward rounds with particular reference to: documentation of clinical observations and National Early Warning Score (NEWS), compliance with Trust guidance for venous thromboembolism (VTE) risk assessment, antibiotic stewardship, palliative care and treatment escalation plans (TEP). This quality improvement project was conceived to ensure these parameters were considered and documented during the ward round, thereby improving patient care and safety...
2018: BMJ Open Quality
A Valero, A M Navarro, A Del Cuvillo, I Alobid, J R Benito, C Colás, G de Los Santos, R Fernández Liesa, A García-Lliberós, R González-Pérez, A Izquierdo-Domínguez, A Jurado-Ramos, M M Lluch-Bernal, J R Montserrat Gili, J Mullol, A Puiggròs Casas, M C Sánchez-Hernández, F Vega, J M Villacampa, M Armengot-Carceller, M T Dordal
Nasal obstruction (NO) is defined as the subjective perception of discomfort or difficulty in the passage of air through the nostrils. It is a common reason for consultation in primary and specialized care and may affect up to 30%-40% of the population. It affects quality of life (especially sleep) and lowers work efficiency. The aim of this document is to agree on how to treat NO, establish a methodology for evaluating and diagnosing it, and define an individualized approach to its treatment. NO can be unilateral or bilateral, intermittent or persistent and may be caused by local or systemic factors, which may be anatomical, inflammatory, neurological, hormonal, functional, environmental, or pharmacological in origin...
2018: Journal of Investigational Allergology & Clinical Immunology
(no author information available yet)
No abstract text is available yet for this article.
December 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
C Philpott, S Erskine, R Smith, C Hopkins, N Kara, A Farboud, M Salam, A Robertson, R Almeyda, B N Kumar, S Anari, J Ray, R Cathcart, S Carrie, S Ahmed, H Khalil, A Clark, M Thomas
OBJECTIVES: According to clinical and comissioning guidelines for chronic rhinosinusitis (CRS), patients being referred to secondary care should have failed primary medical treatment with nasal douching (ND) and intranasal corticosteroids (INCS). The study objectives were to identify the rate of specific medical therapy in CRS patients and establish any differences in medication use, for both CRS and associated medical conditions, between CRS phenotypes. DESIGN AND SETTING: Case-control study in a secondary care setting...
April 2018: Clinical Otolaryngology
Yvan Vandenplas
Introduction: The prevention and management of cow milk allergy (CMA) is still debated. Since CMA is much less frequent in breastfed infants, breastfeeding should be stimulated. Method: Literature was searched using databases to find original papers and reviews on this topic. Results: Hydrolysates with a clinical proof of efficacy are recommended in the prevention and treatment of CMA. However, not all meta-analyses conclude that hydrolysates do prevent CMA or other atopic manifestations such as atopic dermatitis...
July 10, 2017: Nutrients
Yvan Vandenplas, Philippe Steenhout, Anette Järvi, Anne-Sophie Garreau, Rajat Mukherjee
PURPOSE: The diagnosis of cow's milk (CM) allergy is a challenge. The Cow's Milk-related-Symptom-Score (CoMiSS™) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the CoMiSS™ was evaluated in three clinical trials. METHODS: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 challenge test on the month-1 CoMiSS™, adjusting for baseline CoMiSS™ using a logistic regression model...
March 2017: Pediatric Gastroenterology, Hepatology & Nutrition
Christophe Dupont, Elena Bradatan, Pascale Soulaines, Rita Nocerino, Roberto Berni-Canani
BACKGROUND: In case of cow's milk allergy (CMA), pediatric guidelines recommend for children the use of extensively hydrolyzed formulas (eHFs) as elimination diet. According to the American Academy of Pediatrics, the hypoallergenicity of each specific eHF should be tested in subjects with CMA. METHODS: A prospective, multicenter trial was performed to assess the tolerance/hypoallergenicity of a thickened casein-based eHF (eHCF, Allernova AR®, United Pharmaceuticals, France) in infants aged <12 months with CMA proven by a double-blind placebo-controlled food challenge...
July 18, 2016: BMC Pediatrics
S Kasturi, V Sivakumar, U V Varadaraju
A series of Eu(2+) -activated barium orthosilicates (BaZnSiO4 ) were synthesized using a high-temperature solid-state reaction. A photoluminescence excitation study of Eu(2)(+) shows a broad absorption band in the range of 270-450 nm, with multiple absorption peak maxima (310, 350 and 400 nm) due to 4f-5d electronic transition. The emission spectra of all the compositions show green color emission (in the spectral region 450-550 nm with a peak maximum at 502 nm and a shoulder at ~ 490 nm) with appropriate Comission Internationale de l'Eclairage (CIE) color coordinates...
May 2017: Luminescence: the Journal of Biological and Chemical Luminescence
(no author information available yet)
The National Institute for Health and Clinical Excellence (NICE) has published six new guides to help NHS staff commission evidence based care for patients.
February 1, 2008: Nursing Management (Harrow)
Andrew McCarthy
No abstract text is available yet for this article.
September 2015: Australian Nursing & Midwifery Journal
Yvan Vandenplas, Johan Marchand, Lien Meyns
INTRODUCTION: The diagnosis and management of cow's milk allergy (CMA) is a topic of debate because there are no specific symptoms and reliable diagnostic tests. METHOD: Literature was searched using databases to find original papers and reviews on this topic. RESULTS: A "challenge test" is still recommended as the most specific and sensitive diagnostic test, although a positive challenge test does not proof the involvement of the immune system...
2015: Current Pediatric Reviews
Seda Cengiz, Emir Yüzbaşioğlu, M Inanç Cengiz, Neslin Velioğlu, Gaye Sevimli
STATEMENT OF THE PROBLEM: Mouthrinses can cause discoloration on indirect resin composites. PURPOSE OF THE STUDY: The purpose of the study was to investigate the effect of different mouthrinses on the color changes and surface roughness of a laboratory-processed composite. METHODS AND MATERIALS: Fifty discs were made using GC Gradia/GC indirect composites and divided into five groups which immersed in artificial saliva and four different types of mouthrinses...
September 2015: Journal of Esthetic and Restorative Dentistry
Yvan Vandenplas, Christophe Dupont, Philippe Eigenmann, Arne Host, Mikael Kuitunen, Carmen Ribes-Koninckx, Neil Shah, Raanan Shamir, Annamaria Staiano, Hania Szajewska, Andrea Von Berg
UNLABELLED: Clinicians with expertise in managing children with gastrointestinal problems and/or atopic diseases attended a workshop in Brussels in September 2014 to review the literature and determine whether a clinical score derived from symptoms associated with the ingestion of cow's milk proteins could help primary healthcare providers. The Cow's Milk-related Symptom Score (CoMiSS), which considers general manifestations, dermatological, gastrointestinal and respiratory symptoms, was developed as an awareness tool for cow's milk-related symptoms...
April 2015: Acta Paediatrica
Jan Babica, Václav Rusek
UNLABELLED: In the 1920s Czechoslovakia, an increased attention was paid to the new ideas of scientific management (Taylorism), work rationalization and standardization. This was reflected in the foundation of the Masaryk Academy of Work in 1920. An effort to implement the new principles into health care led to the establishment of the Commission for Rationalization and Standardization in Medicine, Veterinary Medicine and Pharmacy (RANOK) within the Department of Natural Science and Medicine of the Academy...
June 2014: Ceská a Slovenská Farmacie
Hannah Stanwix
Patrick Couvreur speaks to Hannah Stanwix, Managing Comissioning Editor: Professor Patrick Couvreur received his pharmacy degree from the Université Catholique de Louvain (Louvain-la-Neuve, Belgium) in 1972. He holds a PhD in pharmaceutical technology from the same university and completed a postdoctoral fellowship at the Eidgenössische Technische Hochschule (Zürich, Switzerland). Since 1984, Professor Couvreur has been Full Professor of Pharmacy at the Paris-Sud University (Paris, France) and was holder of the Chair of Innovation Technologique at the prestigious Collège de France (Paris, France)...
May 2014: Nanomedicine
Shaun Treweek, Adam Born
Professor Shaun Treweek speaks to Adam Born, Assistant Comissioning Editor: Professor Shaun Treweek is Chair in Health Services Research at the University of Aberdeen (UK) and has over 18 years experience as a health services researcher specializing in trial methodology. He is active in the field of pragmatic trial design, the design and pretrial testing of complex interventions, interventions to improve recruitment to trials, and theory-based methods to assess the implementation potential of interventions...
May 2014: Journal of Comparative Effectiveness Research
María Casado, Itziar de Lecuona
This paper identifies problems and analyzes those conflicts posed by the evaluation of research projects involving the collection and use of human induced pluripotent stem cells (iPS) in Spain. Current legislation is causing problems of interpretation, circular and unnecessary referrals, legal uncertainty and undue delays. Actually, this situation may cause a lack of control and monitoring, and even some paralysis in regenerative medicine and cell therapy research, that is a priority nowadays. The analysis of the current legislation and its bioethical implications, led us to conclude that the review of iPS research projects cannot be assimilated to the evaluation of research projects that involve human embryonic stem cell (hESC)...
July 2013: Revista de Derecho y Genoma Humano, Law and the Human Genome Review
C Matthew Hawkins, Seth Hall, Bin Zhang, Alexander J Towbin
The purpose of this study was to evaluate and compare textual error rates and subtypes in radiology reports before and after implementation of department-wide structured reports. Randomly selected radiology reports that were generated following the implementation of department-wide structured reports were evaluated for textual errors by two radiologists. For each report, the text was compared to the corresponding audio file. Errors in each report were tabulated and classified. Error rates were compared to results from a prior study performed prior to implementation of structured reports...
October 2014: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Jindřich Kopeček, Hannah Stanwix
Jindřich Kopeček speaks to Hannah Stanwix, Managing Comissioning Editor: Jindřich Henry Kopeček received his PhD in Macromolecular Chemistry and DSc in Chemistry from the Czechoslovak Academy of Sciences (Czech Republic). His postdoctoral studies were at the National Research Council of Canada. He is currently a Distinguished Professor at the University of Utah (UT, USA) in Pharmaceutics and Pharmaceutical Chemistry, and Bioengineering. Dr Kopeček has received numerous awards in his career, including the Millennial Pharmaceutical Scientist accolade...
April 2014: Nanomedicine
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