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https://www.readbyqxmd.com/read/28534280/a-prospective-cohort-study-of-insomnia-and-chronic-kidney-disease-in-japanese-workers
#1
Sachiko Sasaki, Eiji Yoshioka, Yasuaki Saijo, Akira Bannai, Toshiko Kita, Akiko Tamakoshi, Reiko Kishi
PURPOSE: The role of insomnia in chronic kidney disease (CKD) is controversial. To date, there have been no prospective studies investigating insomnia, CKD and the effect of shift work. We assessed insomnia and CKD risk in a prospective, occupational cohort study. METHODS: A total of 3600 participants with normal kidney function were followed for an average of 4.4 years. Insomnia was assessed using the Athens Insomnia Scale (AIS). CKD was defined as an estimated glomerular filtration rate of <60 mL/min/1...
May 22, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28515957/a-psychologically-informed-audiologist-delivered-manualised-intervention-for-tinnitus-protocol-for-a-randomised-controlled-feasibility-trial-tin-man-study
#2
John A Taylor, Deborah A Hall, Dawn-Marie Walker, Mary McMurran, Amanda Casey, David Stockdale, Debbie Featherstone, Dean M Thompson, Carol MacDonald, Derek J Hoare
BACKGROUND: Chronic tinnitus is a common incurable condition often associated with depression, anxiety, insomnia and reduced quality of life. Within National Health Service (NHS) audiology in the United Kingdom (UK), no standard protocol currently exists for the treatment of tinnitus. Counselling is only available in less than half of audiology departments, and there is no agreed standard for what constitutes tinnitus counselling. There is substantial evidence from systematic reviews for the clinical benefit of cognitive behaviour therapy (CBT) for tinnitus delivered by clinical psychologists or psychiatrists, but no studies have sufficiently evidenced the NHS model of tinnitus care where management is increasingly being delivered by audiology professionals...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28511597/understanding-sleep-wake-mechanisms-and-drug-discovery
#3
Ana Clementina Equihua-Benítez, Khalil Guzmán-Vásquez, René Drucker-Colín
Although not discernible at first glance, sleep is a highly active and regulated brain state. Although we spend practically one third of our lifetimes in this stage, its importance is often taken for granted. Sleep loss can lead to disease, error and economic loss. Our understanding of how sleep is achieved has greatly advanced in recent years, and with that, the management of sleep disorders has improved. Nevertheless, there is still room for improvement and recently many new compounds have reached clinical trials with a few being approved for commercial use...
May 17, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28503402/physical-exercise-for-treatment-of-mood-disorders-a-critical-review
#4
C M Hearing, W C Chang, K L Szuhany, T Deckersbach, A A Nierenberg, L G Sylvia
PURPOSE OF THE REVIEW: The purpose of this review is to critically assess the evidence for exercise as an adjunct intervention for major depressive disorder and bipolar disorder, chronic conditions characterized by frequent comorbid conditions as well as interepisodic symptoms with poor quality of life and impaired functioning. Individuals with these mood disorders are at higher risk of cardiovascular disease and premature death in part because of increased rates of obesity, inactivity, and diabetes mellitus compared to the general population...
December 2016: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/28502070/sleep-in-children-with-autism-spectrum-disorder
#5
REVIEW
Margaret C Souders, Stefanie Zavodny, Whitney Eriksen, Rebecca Sinko, James Connell, Connor Kerns, Roseann Schaaf, Jennifer Pinto-Martin
The purposes of this paper are to provide an overview of the state of the science of sleep in children with autism spectrum disorder (ASD), present hypotheses for the high prevalence of insomnia in children with ASD, and present a practice pathway for promoting optimal sleep. Approximately two thirds of children with ASD have chronic insomnia, and to date, the strongest evidence on promoting sleep is for sleep education, environmental changes, behavioral interventions, and exogenous melatonin. The Sleep Committee of the Autism Treatment Network (ATN) developed a practice pathway, based on expert consensus, to capture best practices for screening, identification, and treatment for sleep problems in ASD in 2012...
June 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28500199/data-quality-in-electronic-medical-records-in-manitoba-do-problem-lists-reflect-chronic-disease-as-defined-by-prescriptions
#6
Alexander Singer, Andrea L Kroeker, Sari Yakubovich, Roberto Duarte, Brenden Dufault, Alan Katz
OBJECTIVE: To determine if the problem list (health conditions) in primary care electronic medical records (EMRs) accurately reflects the conditions for which chronic medications are prescribed in the EMR. DESIGN: A retrospective analysis of EMR data. SETTING: Eighteen primary care clinics across rural and urban Manitoba using the Accuro EMR. PARTICIPANTS: Data from the EMRs of active patients seen in an 18-month period (December 18, 2011, to June 18, 2013, or December 3, 2012, to June 3, 2014) were used...
May 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28499301/-validation-of-the-german-version-of-tinnitus-functional-index-tfi
#7
Petra Brüggemann, Agnieszka J Szczepek, Tobias Kleinjung, Michael Ojo, Birgit Mazurek
Tinnitus belongs to seriously debilitating auditory conditions and is often complicated by comorbidities such as insomnia, difficulties with concentration, depression, frustration and irritability. To facilitate the grading of symptoms and the effects of therapeutic strategies, we validated a German-version Tinnitus Functional Index (TFI) in 229 subjects suffering from chronic tinnitus. Outcome validity was assessed using the Tinnitus Questionnaire (TQ, German adaptation by Goebel u. Hiller [1998]). Construct validity was assessed using the "Hamburger Allgemeine Depressionsskala" (HADS)...
May 12, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28498551/sofosbuvir-velpatasvir-with-ribavirin-for-24-weeks-in-hcv-patients-previously-treated-with-a-direct-acting-antiviral-regimen
#8
Edward J Gane, Mitchell L Shiffman, Kyle Etzkorn, Giuseppe Morelli, Catherine Stedman, Mitchell N Davis, Federico Hinestrosa, Hadas Dvory-Sobol, K C Huang, Anu Osinusi, John McNally, Diana M Brainard, John G McHutchison, Alex J Thompson, Mark S Sulkowski
The optimal retreatment strategy for patients chronically infected with hepatitis C virus (HCV) who experience virologic failure after treatment with direct-acting antiviral (DAA)-based therapies remains unclear. In this multicenter, open-label, phase 2 study, we evaluated the efficacy and safety of a fixed-dose combination of sofosbuvir-velpatasvir (400 mg/100 mg) plus weight-adjusted ribavirin administered for 24 weeks in patients who did not achieve sustained virologic response (SVR) after prior treatment with DAA regimens that included the nucleotide analogue NS5B inhibitor sofosbuvir plus the NS5A inhibitor velpatasvir with or without the NS3/4A protease inhibitor voxilaprevir...
May 12, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28484405/management-of-chronic-tinnitus-and-insomnia-with-repetitive-transcranial-magnetic-stimulation-and-cognitive-behavioral-therapy-a-combined-approach
#9
Kneginja Richter, Jens Acker, Lence Miloseva, Lukas Peter, Günter Niklewski
It has been estimated that up to 80% of people will experience symptoms of tinnitus over the courses of their lives, with rates of comorbid sleeping problems ranging from 50 to 77%. Because of a potential connection between tinnitus and sleep disorders as well as high rates of comorbid psychiatric disorders, interdisciplinary approaches to treatment seem to be the most efficient option. In this study, we present the case of a 53-year-old male patient, who started to experience symptoms of tinnitus at the age of 49, most likely caused by work-related stress...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28483186/impact-of-acupuncture-on-chronic-insomnia-a-report-of-two-cases-with-polysomnographic-evaluation
#10
Sibel Mandıroğlu, Cigdem Ozdilekcan
OBJECTIVE: This report aimed to present the acupuncture treatment response of two patients who were evaluated with polysomnography. CLINICAL FEATURES: Acupuncture treatment was planned for two patients who refused medical treatment with chronic insomnia. Polysomnographic evaluation was performed at baseline and 1 month after acupuncture treatment. CONCLUSION: Remarkable improvement was determined in polysomnographic parameters of both cases...
April 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28481358/decreased-alertness-due-to-sleep-loss-increases-pain-sensitivity-in-mice
#11
Chloe Alexandre, Alban Latremoliere, Ashley Ferreira, Giulia Miracca, Mihoko Yamamoto, Thomas E Scammell, Clifford J Woolf
Extended daytime and nighttime activities are major contributors to the growing sleep deficiency epidemic, as is the high prevalence of sleep disorders like insomnia. The consequences of chronic insufficient sleep for health remain uncertain. Sleep quality and duration predict presence of pain the next day in healthy subjects, suggesting that sleep disturbances alone may worsen pain, and experimental sleep deprivation in humans supports this claim. We demonstrate that sleep loss, but not sleep fragmentation, in healthy mice increases sensitivity to noxious stimuli (referred to as 'pain') without general sensory hyper-responsiveness...
May 8, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28470767/sleep-wake-rhythm-disturbances-and-perceived-sleep-in-adolescent-chronic-fatigue-syndrome
#12
Maria Pedersen, Mirjam Ekstedt, Milada C Småstuen, Vegard B Wyller, Dag Sulheim, Even Fagermoen, Anette Winger, Edvard Pedersen, Harald Hrubos-Strøm
Chronic fatigue syndrome (CFS) is characterized by long-lasting, disabling and unexplained fatigue that is often accompanied by unrefreshing sleep. The aim of this cross-sectional study was to investigate sleep-wake rhythm and perceived sleep in adolescent CFS patients compared to healthy individuals. We analysed baseline data on 120 adolescent CFS patients and 39 healthy individuals included in the NorCAPITAL project. Activity measures from a uniaxial accelerometer (activPAL) were used to estimate mid-sleep time (mid-point of a period with sleep) and time in bed...
May 4, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28470725/sleep-disorders-and-an-increased-risk-of-parkinson-s-disease-in-individuals-with-non-apnea-sleep-disorders-a-population-based-cohort-study
#13
Yi-Han Hsiao, Yung-Tai Chen, Ching-Ming Tseng, Li-An Wu, Diahn-Warng Perng, Yuh-Min Chen, Tzeng-Ji Chen, Shi-Chuan Chang, Kun-Ta Chou
Sleep disorders are common non-motor symptoms in patients with Parkinson's disease. Our study aims to explore the relationship between non-apnea sleep disorders and future Parkinson's disease. This is a cohort study using a nationwide database. The participants were recruited from the Taiwan National Health Insurance Research Database between 2000 and 2003. A total of 91 273 adult patients who had non-apnea sleep disorders without pre-existing Parkinson's disease were enrolled. An age-, gender-, income-, urbanization- and Charlson comorbidity index score-matched control cohort consisting of 91 273 participants was selected for comparison...
May 4, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28468061/-distributions-and-associations-between-duration-of-sleep-daytime-naps-and-insomnia-symptoms-among-chinese-adults
#14
B Zheng, L L Lin, C Q Yu, J Lyu, Y Guo, Z Bian, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To investigate the distribution of sleep duration, daytime naps habits, and insomnia-related symptoms among participants from the China Kadoorie Biobank (CKB) study, and to examine the associations between the sleep-associated factors. Methods: A self-designed computer-based questionnaire was adopted to collect social-demographic information and lifestyle-related factors of the participants. A total of 452 829 Chinese adults aged 30-79 years, without self-reported histories of coronary heart disease, stroke, chronic obstructive pulmonary diseases or cancer, were included in this study...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28467286/uncovering-common-sleep-disorders-and-their-impacts-on-occupational-performance
#15
Sylvia R Judd
Sleep is an active process; the body undergoes restoration and regeneration. Adequate sleep is essential to health and cognitive function. Sleep is critical for cell repair, a healthy immune system, and hormonal regulation, and aids in the process of learning, memory, and emotion. Inadequate sleep can lead to multiple chronic health and mental conditions over time. The occupational health nurse can be instrumental in screening for two of the most common sleep disorders, insomnia and obstructive sleep apnea, by asking workers key questions and using simple screening tools...
May 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28465612/incidence-worsening-and-risk-factors-of-daytime-sleepiness-in-a-population-based-5-year-longitudinal-study
#16
I Jaussent, C M Morin, H Ivers, Y Dauvilliers
Excessive daytime sleepiness (EDS) is highly prevalent in the general population; however little is known about its evolution and predictors. Our objectives were to document its natural history, provide estimates of its prevalence, incidence and persistence rates, and to identify predictors of increased daytime sleepiness (DS) in a longitudinal community study of 2157 adults over 5 years. Participants completed postal assessment at baseline and at each yearly follow-up. DS was evaluated by the Epworth Sleepiness scale (ESS)...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28463015/effectiveness-of-group-cognitive-behavioral-therapy-for-insomnia-cbt-i-in-a-primary-care-setting
#17
Judith R Davidson, Samantha Dawson, Adrijana Krsmanovic
OBJECTIVE/BACKGROUND: Primary care is where many patients with insomnia first ask for professional help. Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended treatment for chronic insomnia. Although CBT-I's efficacy is well established, its effectiveness in real-life primary care has seldom been investigated. We examined the effectiveness of CBT-I as routinely delivered in a Canadian primary care setting. PARTICIPANTS: The patients were 70 women and 11 men (mean age = 57...
May 2, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28461786/prospective-evaluation-of-anxiety-depression-and-quality-of-life-in-medically-inoperable-early-stage-non-small-cell-lung-cancer-patients-treated-with-stereotactic-ablative-radiotherapy
#18
Jacek Rutkowski, Magdalena Szymanik, Maciej Blok, Joanna Kozaka, Renata Zaucha
AIM: The aim of this prospective study was to evaluate the level of anxiety, depression, and quality of life (QoL) in medically inoperable patients with early stage non-small cell lung cancer (NSCLC) treated with stereotactic ablative radiotherapy (SABR). BACKGROUND: Prolonged survival is equally important as maintaining high QoL and good psychological functioning during the treatment of lung cancer. Nowadays available SABR has markedly changed clinical care and outcomes in the group of medically inoperable patients...
May 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/28456150/structural-and-construct-validity-of-the-czech-version-of-the-pittsburgh-sleep-quality-index-in-chronic-insomnia
#19
Daniela Dudysová, Ivana Malá, Karolína Mladá, Elizaveta Saifutdinova, Jana Koprivova, Peter Sos
OBJECTIVES: The Pittsburgh Sleep Quality Index (PSQI) is one of the widely used and recommended measures of assessing sleep quality in chronic insomnia; however certain psychometric properties of the questionnaire are still unknown in this group of patients. The present study aimed to examine the internal consistency, and structural and convergent validity of the Czech version of the PSQI in chronic insomnia patients. The usefulness of the standard and alternative scoring systems was also investigated in relation to symptoms of sleepiness, insomnia, depression, and anxiety...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28449911/psychometric-properties-of-the-sleep-condition-indicator-and-insomnia-severity-index-in-the-evaluation-of-insomnia-disorder
#20
Mark Lawrence Wong, Kristy Nga Ting Lau, Colin A Espie, Annemarie I Luik, Simon D Kyle, Esther Yuet Ying Lau
OBJECTIVE: The Sleep Condition Indicator (SCI) and Insomnia Severity Index (ISI) are commonly used instruments to assess insomnia. We evaluated their psychometric properties, particularly their discriminant validity against structured clinical interview (according to DSM-5 and ICSD-3), and their concurrent validity with measures of sleep and daytime functioning. METHODS: A total of 158 young adults, 16% of whom were diagnosed with DSM-5 insomnia disorder and 13% with ICSD-3 Chronic Insomnia by structured interview, completed the ISI and SCI twice in 7-14 days, in addition to measures of sleep and daytime function...
May 2017: Sleep Medicine
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