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https://www.readbyqxmd.com/read/27926985/tropical-rainforests-that-persisted-inferences-from-the-quaternary-demographic-history-of-eight-tree-species-in-the-guiana-shield
#1
Stéphanie Barthe, Giorgio Binelli, Bruno Hérault, Caroline Scotti-Saintagne, Daniel Sabatier, Ivan Scotti
How Quaternary climatic and geological disturbances influenced the composition of Neotropical forests is hotly debated. Rain fall and temperature changes during and/or immediately after the Last Glacial Maximum (LGM) are thought to have strongly affected the geographical distribution and local abundance of tree species. The paucity of the fossil records in Neotropical forests prevents a direct reconstruction of such processes. To describe community-level historical trends in forest composition, we turned therefore to inferential methods based on the reconstruction of past demographic changes...
December 7, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27926972/management-of-endometriosis-in-the-infertile-patient
#2
Edgardo Somigliana, Paola Vigano, Laura Benaglia, Andrea Busnelli, Nicola Berlanda, Paolo Vercellini
The management of endometriosis-related infertility remains debated. However, in recent years, the role of in vitro fertilization (IVF) has progressively grown. Reasons to explain this change include (1) the improvement of the effectiveness and safety of IVF, (2) the raised awareness of the modest effectiveness of surgery, (3) the inherent risks of surgery including in particular the damage to the ovarian reserve when ovarian endometriomas have to be removed, (4) the ineffectiveness of intrauterine insemination and the possible risks of endometriosis progression associated with the use of this technique...
December 7, 2016: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27926691/on-treatment-blood-pressures-of-older-hypertensive-patients-in-canada-implications-for-systolic-blood-pressure-intervention-trial
#3
Jiri George Fodor, Penelope Baker, Li Chen, Frans H H Leenen
OBJECTIVE: The therapeutic target level for the blood pressure (BP) on antihypertensive drug treatment in older hypertensive patients is still extensively debated. We assessed the achieved BP levels in older treated hypertensive patients in a representative sample of the population. DESIGN: During the 2006 Ontario Survey on the Prevalence and Control of Hypertension, BP (using the SPRINT protocol) and treatment data were collected in 2551 respondents from a random and representative sample of the adult (20-79 years) population...
December 6, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27926613/optimal-multidisciplinary-treatment-of-oral-cavity-mucosal-melanoma-outcome-analysis-in-a-case-series
#4
Francesco Perri, Salvatore Pisconti, Matteo Favia, Giuseppina Della Vittoria Scarpati, Manuel Conson, Mario Giuliano, Franco Ionna, Francesco Longo, Bonamonte Domenico, Eugenio Maiorano, Gianfranco Favia
Oral cavity mucosal melanomas (OCMM) represent only 3% of all malignant melanomas. Surgery is the mainstay of treatments and it is often followed by adjuvant radiotherapy. The role of adjuvant immunotherapy and/or chemotherapy is still debated and to date neither treatment is routinely used. From January 1990 to January 2010, we have collected from our database data of 20 patients with a histologically proven diagnosis of OCMM. Upfront surgery, followed by adjuvant radiotherapy was performed in 16/20 (80%) patients...
December 6, 2016: Anti-cancer Drugs
https://www.readbyqxmd.com/read/27926491/early-pathogenic-event-of-alzheimer-s-disease-documented-in-ipscs-from-patients-with-psen1-mutations
#5
Juan Yang, Hanzhi Zhao, Yu Ma, Guilai Shi, Jian Song, Yu Tang, Song Li, Ting Li, Nan Liu, Fan Tang, Junjie Gu, Lingling Zhang, Zhuohua Zhang, Xiaohui Zhang, Ying Jin, Weidong Le
Alzheimer's disease (AD) is the most common age-related dementia characterized by progressive neuronal loss. However, the molecular mechanisms for the neuronal loss is still debated. Here, we used induced pluripotent stem cells (iPSCs) derived from somatic cells of familial AD patients carrying PSEN1 mutations to study the early pathogenic event of AD. We found that premature neuronal differentiation with decreased proliferation and increased apoptosis occured in AD-iPSC-derived neural progenitor cells (AD-NPCs) once neuronal differentiation was initiated, together with higher levels of Aβ42 and phosphorylated tau...
December 2, 2016: Oncotarget
https://www.readbyqxmd.com/read/27926466/chest-wall-resection-for-mesothelioma-recurrence-after-surgery
#6
Pietro Bertoglio, Olivia Fanucchi, Sara Ricciardi, Antonio Chella, Marco Lucchi, Alfredo Mussi
Malignant pleural mesothelioma is an aggressive and usually fatal disease, and its optimal management is still under debate. Surgery for recurrent malignant mesothelioma has been reported rarely in highly selected cases. We report a case of chest wall resection for local recurrence of epithelioid mesothelioma 3 years after cytoreductive surgery. Our patient experienced a 6-month disease-free survival after redo surgery, with complete resolution of his chest pain and discomfort.
November 2016: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/27926438/exploring-individual-differences-in-task-switching-persistence-and-other-personality-traits-related-to-anterior-cingulate-cortex-function
#7
A Umemoto, C B Holroyd
Anterior cingulate cortex (ACC) is involved in cognitive control and decision-making but its precise function is still highly debated. Based on evidence from lesion, neurophysiological, and neuroimaging studies, we have recently proposed a critical role for ACC in motivating extended behaviors according to learned task values (Holroyd and Yeung, 2012). Computational simulations based on this theory suggest a hierarchical mechanism in which a caudal division of ACC selects and applies control over task execution, and a rostral division of ACC facilitates switches between tasks according to a higher task strategy (Holroyd and McClure, 2015)...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27925732/effect-of-nematic-order-on-the-low-energy-spin-fluctuations-in-detwinned-bafe_-1-935-ni_-0-065-as_-2
#8
Wenliang Zhang, J T Park, Xingye Lu, Yuan Wei, Xiaoyan Ma, Lijie Hao, Pengcheng Dai, Zi Yang Meng, Yi-Feng Yang, Huiqian Luo, Shiliang Li
The origin of nematic order remains one of the major debates in iron-based superconductors. In theories based on spin nematicity, one major prediction is that the spin-spin correlation length at (0,π) should decrease with decreasing temperature below the structural transition temperature T_{s}. Here, we report inelastic neutron scattering studies on the low-energy spin fluctuations in BaFe_{1.935}Ni_{0.065}As_{2} under uniaxial pressure. Both intensity and spin-spin correlation start to show anisotropic behavior at high temperature, while the reduction of the spin-spin correlation length at (0,π) happens just below T_{s}, suggesting the strong effect of nematic order on low-energy spin fluctuations...
November 25, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27925727/can-point-defects-in-surfaces-in-solution-be-atomically-resolved-by-atomic-force-microscopy
#9
Bernhard Reischl, Paolo Raiteri, Julian D Gale, Andrew L Rohl
While the atomic force microscope (AFM) is able to image mineral surfaces in solution with atomic resolution, so far, it has been a matter of debate whether imaging point defects is also possible under these conditions. The difficulties stem from the limited knowledge of what types of defects may be stable in the presence of an AFM tip, as well as from the complicated imaging mechanism involving interactions between hydration layers over the surface and around the tip apex. Here, we present atomistic molecular dynamics and free energy calculations of the AFM imaging of vacancies and ionic substitutions in the calcite (101[over ¯]4) surface in water, using a new silica AFM tip model...
November 25, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27925716/incorporating-noise-quantitatively-in-the-phase-field-crystal-model-via-capillary-fluctuation-theory
#10
Gabriel Kocher, Nana Ofori-Opoku, Nikolas Provatas
A tacit assumption underlying most phase field models of nonequilibrium phase transformations is that of scale separation. Stochastic order parameter field theories utilize noise to separate atomic-scale fluctuations from the slowly varying fields that describe microstructure patterns. The mesoscale distribution of such stochastic variables is generally assumed to follow Gaussian statistics, with their magnitude following fluctuation-dissipation relations. However, there is still much debate about how atomic-scale fluctuations map onto the mesoscale upon coarse graining of microscopic theories...
November 25, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27925675/effect-of-increasing-low-intensity-pulsed-ultrasound-and-a-functional-appliance-on-the-mandibular-condyle-in-growing-rats
#11
Harmanpreet Kaur, Hasan Uludağ, Douglas N Dederich, Tarek El-Bialy
OBJECTIVES: Functional appliances are used for treatment of lower-jaw deficiencies in growing individuals; however, their effectiveness is debatable. Low-intensity pulsed ultrasound (US) is a noninvasive method, which has been shown to stimulate cartilage and bone formation with 20 minutes of application. This study was designed to test the hypothesis that increasing low-intensity pulsed US application from 20 to 40 min/d will enhance mandibular condylar growth in growing rats, especially when combined with a functional appliance...
November 28, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27925652/inclusion-of-a-rest-period-in-diaphragmatic-breathing-increases-high-frequency-heart-rate-variability-implications-for-behavioral-therapy
#12
Matthew E B Russell, April B Scott, Ian A Boggero, Charles R Carlson
Heart rate variability (HRV) is associated with positive physiological and psychological effects. HRV is affected by breathing parameters, yet debate remains regarding the best breathing interventions for strengthening HRV. The objective of the current study was to test whether the inclusion of a postexhalation rest period was effective at increasing HRV, while controlling for breathing rate. A within-subject crossover design was used with 40 participants who were assigned randomly to a breathing pattern including a postexhalation rest period or a breathing pattern that omitted the postexhalation rest period...
December 7, 2016: Psychophysiology
https://www.readbyqxmd.com/read/27925470/induction-of-labour-vs-spontaneous-vaginal-delivery-in-twin-pregnancy-after-36-weeks-of-gestation
#13
Mariana Vide Tavares, Ana Patrícia Domingues, Filipa Nunes, Margarida Tavares, Etelvina Fonseca, Paulo Moura
Time for delivery and delivery pathway in twin pregnancies are still in great debate. Our study goal was to compare the characteristics of delivery and maternal-foetal outcome in uncomplicated near-term twin pregnancies undergoing labour induction and those with spontaneous labour. We found no statistical differences in patients with twin pregnancies who underwent labour induction and those with spontaneous labour regarding the history of previous caesarean delivery, parity, pregnancy achieved by assisted reproductive techniques (ART), chorionicity and cervical dilation at the admission as well as maternal and neonatal morbidity, and admission to the neonatal intensive care unit...
December 7, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27925092/everyday-representations-of-young-people-about-peripheral-areas
#14
Elda de Oliveira, Cassia Baldini Soares, Leandro Leonardo Batista
Objectives: to understand everyday representations of young people about the peripheral areas, with the purpose of establishing topics to drug education media programs. Method: Marxist approach, with emancipatory action research and the participation in workshops of 13 youngsters from a public school of the peripheral area of São Paulo. Results: there are contradictory everyday representations about the State's role, which, on the one hand, does not guarantee social rights and exert social control over the peripheral areas and, on the other hand, is considered the privileged interlocutor for the improvement of life and work conditions...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27925021/thirdhand-smoke-when-the-danger-is-more-than-you-can-see-or-smell
#15
Luciana Rizzieri Figueiró, Ana Luiza Ziulkoski, Denise Conceição Mesquita Dantas
Recent discussion has focused on another form of exposure to tobacco - thirdhand smoke (THS) - consisting of residual pollutants from cigarette smoke that remain in environments. The main concern with THS is based on the presence and persistence of many toxic compounds, some specific nitrosamines from tobacco that have carcinogenic activity. Little is known about THS, and few people are aware of its existence and potential health repercussions, thus highlighting the need to shed light on the subject and incorporate it into the public health debate, as was done with passive smoking several years ago...
December 1, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27924949/genetic-evidence-for-an-east-asian-origin-of-chinese-muslim-populations-dongxiang-and-hui
#16
Hong-Bing Yao, Chuan-Chao Wang, Xiaolan Tao, Lei Shang, Shao-Qing Wen, Bofeng Zhu, Longli Kang, Li Jin, Hui Li
There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924684/fifteen-years-of-epidemiologic-virologic-and-syndromic-influenza-surveillance-a-focus-on-type-b-virus-and-the-effects-of-vaccine-mismatch-in-liguria-region-italy
#17
Cecilia Trucchi, Cristiano Alicino, Andrea Orsi, Chiara Paganino C, Ilaria Barberis, Federico Grammatico, Paola Canepa, Emanuela Rappazzo, Bianca Bruzzone, Laura Sticchi, Filippo Ansaldi
In order to estimate the burden of influenza and to describe the genetic evolutionary pattern and antigenic variability of type B viral strains, data deriving from three surveillance systems active in Liguria region, Northern Italy, were described. Since the re-emergence of the Victoria lineage in 2001, the clinical-epidemiological and syndromic surveillances demonstrated the heavy burden of influenza like illness (ILI) syndrome. Focusing on type B influenza virus, it predominated or played a relevant epidemic role in the 50% of the evaluated influenza seasons...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27924444/bindings-in-working-memory-the-role-of-object-based-attention
#18
Zaifeng Gao, Fan Wu, Fangfang Qiu, Kaifeng He, Yue Yang, Mowei Shen
Over the past decade, it has been debated whether retaining bindings in working memory (WM) requires more attention than retaining constituent features, focusing on domain-general attention and space-based attention. Recently, we proposed that retaining bindings in WM needs more object-based attention than retaining constituent features (Shen, Huang, & Gao, 2015, Journal of Experimental Psychology: Human Perception and Performance, doi: 10.1037/xhp0000018 ). However, only unitized visual bindings were examined; to establish the role of object-based attention in retaining bindings in WM, more emperical evidence is required...
December 6, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27924434/prophylactic-antibiotics-for-percutaneous-endovascular-procedures
#19
REVIEW
N S Greaves, E Katsogridakis, B Faris, D Murray
Percutaneous endovascular techniques are used increasingly in the vascular armamentarium. Commonly performed as day case procedures under local anaesthetic, they are suited to the highly co-morbid vascular patient population. Furthermore, technological advances have resulted in ever improving outcomes for aneurysmal and occlusive disease. Endovascular procedures such as endovascular aneurysm repair or iliac artery stenting are traditionally associated with reduced infectious complications compared to equivalent open techniques...
December 6, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27924059/an-open-label-phase-ii-study-evaluating-first-line-egfr-tyrosine-kinase-inhibitor-erlotinib-in-non-small-cell-lung-cancer-patients-with-tumors-showing-high-egfr-gene-copy-number
#20
Ewa Szutowicz-Zielińska, Krzysztof Konopa, Anna Kowalczyk, Małgorzata Suszko-Każarnowicz, Renata Duchnowska, Aleksandra Szczęsna, Magdalena Ratajska, Aleksander Sowa, Janusz Limon, Wojciech Biernat, Tomasz Burzykowski, Jacek Jassem, Rafał Dziadziuszko
BACKGROUND: First-line treatment with epidermal growth factor receptor (EGFR) inhibitors in NSCLC is effective in patients with activating EGFR mutations. The activity of erlotinib in patients harboring high EGFR gene copy number has been considered debatable. PATIENTS AND METHODS: A multicenter, open-label, single-arm phase II clinical trial was performed to test the efficacy of erlotinib in the first-line treatment of NSCLC patients harboring high EGFR gene copy number defined as ≥4 copies in ≥40% of cells...
December 4, 2016: Oncotarget
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