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https://www.readbyqxmd.com/read/29678393/positive-correlations-between-free-vitamin-d-and-bone-variables-in-a-group-of-young-lebanese-women
#1
Abir Alwan, Maroun Rizkallah, Ghassan Maalouf, Joseph Matta, Fabienne Frenn, Angélique Barakat, Falah Bachour, Amer Sebaaly, Abdel-Jalil Berro, Nathalie Al Rassy, Mirza Howayek, Hassane Zouhal, Rawad El Hage
Optimizing bone mass in adulthood is of great importance to prevent the occurrence of osteoporosis in later age. Vitamin D is an essential component of bone health. Low-serum vitamin D is associated with low bone mineral density (BMD), which is an important predictor of fracture risk. However, most cells, apart from renal tubular cells, are exposed to free rather than to total 25-hydroxyvitamin D. Whether free vitamin D would be a better marker than total vitamin D is still under debate. The aim of the present study was to explore the relationships between serum total vitamin D, vitamin D-binding protein (BP), free vitamin D, and bone parameters in a group of young Lebanese women...
March 26, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29668630/thoracolumbar-spinal-neurenteric-cyst-with-tethered-cord-syndrome-and-extreme-cervical-lordosis-in-a-child-a-case-report-and-literature-review
#2
Zhi Gang Lan, Seidu A Richard, Chuanfen Lei, Siqing Huang
RATIONALE: Neurenteric cysts, are rare benign tumors of the central nervous system that are mostly located in the spinal cord and predominantly seen in male children although adult form of the disorder also occurs. The etiology and treatment of this disorder is still a matter of debate. Our case further throws more light on the pathogenesis and treatment of this disorder. PATIENT CONCERNS: A 4-year-old boy presented with 5-month history of cervical lordosis and bilateral lower extremity pain that progressed to his abdomen and upper body...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29649087/activity-of-daily-living-after-long-level-fusion-in-adult-spinal-deformity-compared-with-over-60-years-old-degenerative-spine-patients-without-adult-spinal-deformity
#3
Whoan Jeang Kim, Jae Won Lee, Seok Young Hwang, Kun Young Park, Shann Haw Chang, Dae Geon Song, Won Sik Choy
STUDY DESIGN: Prospective single center study. OBJECTIVE: The aim of this study was to evaluate 1) the activity of daily living (ADL) of three categorized patients group; over sixty-year old degenerative spine patients without adult spinal deformity (ASD), non-operative ASD patients, and operative ASD patients, 2) what kinds of activities would be impaired, and 3) how the ADL changes over time after long level fusion. SUMMARY OF BACKGROUND DATA: There is still debate how surgeons could decide treatment methods for old aged adult spinal deformity, operatively or not...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29565943/an-update-of-the-systematic-appraisal-of-the-accuracy-and-utility-of-discography-in-chronic-spinal-pain
#4
Laxmaiah Manchikanti, Amol Soin, Ramsin M Benyamin, Vijay Singh, Frank Je Falco, Aaron K Calodney, Vahid Grami, Joshua A Hirsch
BACKGROUND: The intervertebral disc has been implicated as a major cause of chronic spinal pain based on clinical, basic science, and epidemiological research. There is, however, a lack of consensus regarding the diagnosis and treatment of intervertebral disc disorders. Based on controlled evaluations, lumbar intervertebral discs have been shown to be the source of chronic back pain without disc herniation in 26% to 39% of patients, and in 16% to 53% of patients with pain in the cervical spine...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29564611/a-review-of-lumbosacral-transitional-vertebrae-and-associated-vertebral-numeration
#5
REVIEW
Jayson Lian, Nicole Levine, Woojin Cho
PURPOSE: To review the current literature on methods of accurate numeration of vertebral segments in patients with Lumbosacral transitional vertebrae (LSTVs). LSTVs are a common congenital anomaly of the L5-S1 junction. While their clinical significance has been debated, unquestionable is the need for their identification prior to spinal surgery. We hypothesize that there are no reliable landmarks by which we can accurately number transitional vertebrae, and thus a full spinal radiograph is required...
March 21, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29551629/ewing-sarcoma-of-the-chest-wall-prognostic-factors-of-multimodal-therapy-including-en-bloc-resection
#6
Bastien Provost, Gilles Missenard, Ciprian Pricopi, Olaf Mercier, Sacha Mussot, Dominique Fabre, Nathaniel Langer, Olivier Mir, Cécile Le Pechoux, Philippe Dartevelle, Elie Fadel
BACKGROUND: Radiotherapy has long been the treatment of choice for local control of Ewing sarcoma of the chest wall (ESCW). However, there is debate regarding the use of surgery versus RT. Our objective was to identify risk factors that may affect long-term outcomes of non-metastatic ESCW all treated with preoperative chemotherapy followed by en-bloc resection and adjuvant Chemotherapy or Chemoradiation. METHODS: Between 1996 and 2014, 30 patients with a median age of 25 years (SD +/-8...
March 15, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29547951/anterior-reduction-and-fusion-of-cervical-facet-dislocations
#7
Christian B Theodotou, George M Ghobrial, Andrew L Middleton, Michael Y Wang, Allan D Levi
BACKGROUND: Cervical facet dislocations are among the most common traumatic spinal injuries. Posterior, anterior, and combined surgical approaches have been described and are widely debated. OBJECTIVE: To demonstrate efficacy in anterior-only surgical management for subaxial cervical facet dislocations. METHODS: A consistent surgical algorithm for cervical facet dislocation was applied over a 19-yr period and analyzed retrospectively in adults with acute unilateral or bilateral facet dislocation of the subaxial cervical spine...
March 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29547459/biological-rationale-for-the-use-of-vertebral-whole-bone-marrow-in-spinal-surgery
#8
Francesca Salamanna, Simona Cepollaro, Deyanira Contartese, Gianluca Giavaresi, Giovanni Barbanti Brodano, Cristiana Griffoni, Alessandro Gasbarrini, Milena Fini
STUDY DESIGN: Laboratory study. OBJECTIVE: Mesenchymal stem cells (MSCs) derived from whole bone marrow aspirate (BMA) and MSCs derived from density-gradient centrifugation were isolated from vertebral bodies and cultured under either hypoxic or normoxic conditions to evaluate their biological characteristics and HOX and TALE signature able to improve spinal surgery procedures. SUMMARY OF BACKGROUND DATA: The use of spinal fusion procedures has increased over the last decades; however, failed fusion still remains an important problem...
March 15, 2018: Spine
https://www.readbyqxmd.com/read/29538700/risk-to-benefit-ratio-of-venous-thromboembolism-prophylaxis-for-neurosurgical-procedures-at-a-quaternary-referral-center
#9
Nitin Agarwal, Georgios A Zenonos, Prateek Agarwal, Frank J Walch, Eileen Roach, Sandra J Stokes, Robert M Friedlander, Peter C Gerszten
BACKGROUND: Pharmacological prophylaxis for venous thromboembolism (VTE) in the neurosurgical population is still a matter of debate, as the risk-to-benefit ratio is not well defined. OBJECTIVE: To further evaluate the risk-to-benefit ratio of VTE prophylaxis (VTEP) for all neurosurgical procedures. METHODS: A prospective evaluation was performed after the initiation of a VTEP protocol for 11 436 patients undergoing neurosurgical procedures over 24 mo...
March 9, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29510816/adjuvant-analgesics-for-spine-surgery
#10
Rikke Vibeke Nielsen
Increasing evidence indicate that pain is insufficiently treated following surgical procedures. It is essential that pain treatment is effective with a minimum of side effects in order to promote postoperative rehabilitation. Multimodal analgesia is most likely an important strategy in reducing postoperative pain. Combinations of different analgesics with different mechanisms of action may have an additive analgesic effect with fewer side effects compared to using a single drug. However, there is still a pronounced lack of documentation for the effect and side effects of these multimodal analgesic regimes...
March 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29504331/neurological-recovery-in-traumatic-spinal-cord-injuries-after-surgical-intervention
#11
Mohammad Naeem Ur Razaq, Bahadar Ali, Muhammad Zahid Khan, Muhammad Waqar, Abdul Satar, Muhammad Arif Khan
BACKGROUND: Spinal injuries are the most devastating injuries and affect every aspect of patients' lives. This may cause lifelong disability due to spinal cord injury. Recovery of neurological functions is highly desirable. Early or late surgical intervention is still debatable, but majority recommend early intervention. The result of late surgical intervention in term of neurological recovery is not clear. This study focuses on neurological recovery after late surgical intervention. The objective of this study was to assess neurological recovery in term of ASIA grading in patients with traumatic spinal cord injury...
January 2018: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29501749/rod-fracture-in-adult-spinal-deformity-surgery-fused-to-the-sacrum-prevalence-risk-factors-and-impact-on-health-related-quality-of-life-in-526-patients
#12
Thamrong Lertudomphonwanit, Michael P Kelly, Keith H Bridwell, Lawrence G Lenke, Steven J McAnany, Prachya Punyarat, Timothy P Bryan, Jacob M Buchowski, Lukas P Zebala, Brenda A Sides, Karen Steger-May, Munish C Gupta
BACKGROUND CONTEXT: Risk factors associated with rod fracture (RF) following adult spinal deformity (ASD) surgery fused to the sacrum remain debatable and the impact of RF on patient-reported outcomes (PROs) after ASD surgery has not been investigated. PURPOSE: To evaluate the prevalence of and risk factors for RF and determine PROs change associated with RF after ASD surgery fused to the sacrum. STUDY DESIGN/SETTING: Retrospective single-center cohort...
February 28, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29501518/variability-in-treatment-for-patients-with-cervical-spine-fracture-and-dislocation-an-analysis-of-107-152-patients
#13
Jing Wang, Adam E M Eltorai, J Mason DePasse, Wesley Durand, Daniel Reid, Alan H Daniels
BACKGROUND: Cervical spine injuries are a common cause of morbidity and mortality, but optimal treatment is debated. Prior studies showed substantial variation in treatment. We examined treatment variation in arthrodesis and halo/tong placement in cervical spine injury patients. METHODS: We used the Healthcare Cost and Utilization Project National Inpatient Sample, 2000-2011. Patients were identified based on International Classification of Diseases, 9th Revision diagnosis codes...
February 28, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29443765/clinical-significance-of-superior-articular-process-as-a-reference-point-for-free-hand-pedicle-screw-insertion-in-thoracic-spine
#14
Tae Hoon Kim, Suk Ha Lee, Jae Hyuk Yang, Jae Young Hong, Seung Woo Suh
The trajectory of the pedicle screw perpendicular to the SAP (superior articular process) is consistent with the universal trajectory presented in the previous study of the entry point using computed tomography. The ideal entry point and trajectory of pedicle screw insertion have been a matter of considerable debate. We attempted to find the relationship between SAP and entry point and trajectory of the pedicle screw.Thoracic spine CT (computed tomography) scans of 9 volunteers were studied. A safe zone for the trajectory of the screw in the axial (MarginAx) and sagittal (MarginSag) was defined as the zone between lines perpendicular to the SAP along the medial and lateral cortex of the pedicle in the axial section, and the superior and inferior cortex in the sagittal section without violation of the pedicle walls...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29438136/risk-factors-for-low-bone-mineral-density-in-pediatric-inflammatory-bowel-disease-the-positive-role-of-physical-activity
#15
Stefano Nobile, Richard J Grand, Helen M Pappa
OBJECTIVE: In pediatric inflammatory bowel disease (IBD), the prevalence of low bone mineral density (BMD) and bone fractures and the relationship between these are still debated. Our aim was to report data from a cohort of pediatric patients with IBD. PATIENTS AND METHODS: Cross-sectional assessment of growth and BMD [(dual-energy x-ray absorptiometry (DXA)] and retrospective chart review were performed to report the lifetime prevalence of bone fractures and clinical associations with patients' data...
February 12, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29433181/craniovertebral-junction-transoral-approach-predictive-factors-of-complications
#16
Aymeric Amelot, Louis-Marie Terrier, Guillaume Lot
BACKGROUND: The transoral approach provides the most direct exposure to extradural lesions of the ventral craniovertebral junction. The morbidity and mortality from this approach greatly limits its use because they are still feared and debated. Using univariable and multivariable logistic regression analyses, this study aims to identify the factors associated with short-term complications in patients undergoing the transoral approach. METHODS: A consecutive cohort analysis of prospectively collected data in several neurosurgery spine departments evaluated 143 consecutive patients who had undergone craniovertebral junction transoral approach surgery...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29372862/damage-capitation-in-the-modern-liability-climate-a-primer-for-neurosurgeons-and-systematic-review-of-the-literature
#17
Jacob R Lepard, Beverly C Walters, Curtis J Rozzelle
OBJECTIVE Neurosurgery, and particularly spine surgery, is among the most highly litigated medical specialties in the US, rendering the current malpractice climate of primary importance to spine surgeons nationwide. One of the primary methods of tort reform in the civil justice system is malpractice damage capitation (or "caps"); however, its efficacy is widely debated. The purpose of this article is to serve as a review for the practicing neurosurgeon, with particular emphasis on short- and long-term effects of damage caps and on the current debate regarding their utility, based on a systematic review of the literature...
January 26, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29352353/regarding-loads-after-spinal-fusion-every-level-should-be-seen-separately-a-musculoskeletal-analysis
#18
A Benditz, S Auer, J F Spörrer, S Wolkerstorfer, J Grifka, F Suess, S Dendorfer
INTRODUCTION: The number of spinal fusion surgeries is steadily increasing and biomechanical consequences are still in debate. The aim of this study is to provide biomechanical insights into the sagittal balance of the spine and to compare spinal load before and after spinal fusion. METHOD: The joint reaction forces of 52 patients were analyzed in proximo-distal and antero-posterior direction from the levels T12-L1 to L5-S1 using musculoskeletal simulations. RESULTS: In 104 simulations, pre-surgical forces were equal to post-surgical...
January 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29201564/an-exceptionally-preserved-armored-dinosaur-reveals-the-morphology-and-allometry-of-osteoderms-and-their-horny-epidermal-coverings
#19
Caleb M Brown
Although the evolution and function of "exaggerated" bony projections in ornithischian dinosaurs has been subject to significant debate recently, our understanding of the structure and morphology of their epidermal keratinized coverings is greatly limited. The holotype of Borealopelta , a new nodosaurid ankylosaur, preserves osteoderms and extensive epidermal structures (dark organic residues), in anatomic position across the entire precaudal length. Contrasting previous specimens, organic epiosteodermal scales, often in the form of horn-like (keratinous) sheaths, cap and exaggerate nearly all osteoderms, allowing for morphometric and allometric analyses of both the bony osteoderms and their horny sheaths...
2017: PeerJ
https://www.readbyqxmd.com/read/29200483/biomechanical-analysis-of-range-of-motion-and-failure-characteristics-of-osteoporotic-spinal-compression-fractures-in-human-cadaver
#20
Robert F Heary, Naresh K Parvathreddy, Nitin Agarwal
Background: Vertebroplasty is a treatment for osteoporotic vertebral compression fractures. The optimal location of needle placement for cement injection remains a topic of debate. As such, the authors assessed the effects of location of two types of cement instillations. In addition, the motion and failure modes at the index and adjacent segments were measured. Materials and Methods: Seven human osteoporotic cadaver spines (T1-L4), cut into four consecutive vertebral segments, were utilized...
November 2017: Indian Journal of Orthopaedics
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