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https://www.readbyqxmd.com/read/29201564/an-exceptionally-preserved-armored-dinosaur-reveals-the-morphology-and-allometry-of-osteoderms-and-their-horny-epidermal-coverings
#1
Caleb M Brown
Although the evolution and function of "exaggerated" bony projections in ornithischian dinosaurs has been subject to significant debate recently, our understanding of the structure and morphology of their epidermal keratinized coverings is greatly limited. The holotype of Borealopelta, a new nodosaurid ankylosaur, preserves osteoderms and extensive epidermal structures (dark organic residues), in anatomic position across the entire precaudal length. Contrasting previous specimens, organic epiosteodermal scales, often in the form of horn-like (keratinous) sheaths, cap and exaggerate nearly all osteoderms, allowing for morphometric and allometric analyses of both the bony osteoderms and their horny sheaths...
2017: PeerJ
https://www.readbyqxmd.com/read/29200483/biomechanical-analysis-of-range-of-motion-and-failure-characteristics-of-osteoporotic-spinal-compression-fractures-in-human-cadaver
#2
Robert F Heary, Naresh K Parvathreddy, Nitin Agarwal
Background: Vertebroplasty is a treatment for osteoporotic vertebral compression fractures. The optimal location of needle placement for cement injection remains a topic of debate. As such, the authors assessed the effects of location of two types of cement instillations. In addition, the motion and failure modes at the index and adjacent segments were measured. Materials and Methods: Seven human osteoporotic cadaver spines (T1-L4), cut into four consecutive vertebral segments, were utilized...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29186747/-volume-growth-of-inpatient-treatments-for-spinal-disease-analysis-of-german-nationwide-hospital-discharge-data-from-2005-to-2014
#3
Ulrike Nimptsch, Claire Bolczek, Melissa Spoden, Ekkehard Schuler, Josef Zacher, Thomas Mansky
Background Marked volume growth of inpatient treatments for spinal disease has been observed since diagnosis related groups (DRG) were introduced as payment for inpatient services in Germany. This study aims to analyse this increase by population and stratified by types of treatment. Material and Methods Using German nationwide hospital discharge data (DRG statistics), inpatient treatments for spinal disease with or without surgery were identified. Trends in case numbers were analysed from 2005 to 2014 with consideration of demographic changes, in order to explore which age groups and which types of treatment are affected by volume growth...
November 29, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29090349/bone-disease-in-axial-spondyloarthritis
#4
REVIEW
Margot Van Mechelen, Giulia Rossana Gulino, Kurt de Vlam, Rik Lories
Axial spondyloarthritis is a chronic inflammatory skeletal disorder with an important burden of disease, affecting the spine and sacroiliac joints and typically presenting in young adults. Ankylosing spondylitis, diagnosed by the presence of structural changes to the skeleton, is the prototype of this disease group. Bone disease in axial spondyloarthritis is a complex phenomenon with the coexistence of bone loss and new bone formation, both contributing to the morbidity of the disease, in addition to pain caused by inflammation...
October 31, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29050896/intraoperative-pedicle-screw-navigation-does-not-significantly-affect-complication-rates-after-spine-surgery
#5
Scott C Wagner, Patrick B Morrissey, Ian D Kaye, Arjun Sebastian, Joseph S Butler, Christopher K Kepler
Various forms of intraoperative computer-assisted navigation technologies exist, and have consistently been shown to improve pedicle screw accuracy. However, the overall clinical effects of inaccurate pedicle screw placement have been debated. We examined the clinical effects of improved pedicle screw accuracy with computer navigation technology in reducing complication rates in patients undergoing multi-level spinal fusion. We retrospectively reviewed the ACS-NSQIP registry utilizing Current Procedural Terminology (CPT) codes 22843 + 22844 to identify patients undergoing spinal instrumentation of greater than 7 levels, as well as the CPT code 61783 to denote the use of intraoperative computer-assisted navigation...
October 16, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29027857/is-there-added-value-in-obtaining-cervical-spine-mri-in-the-assessment-of-nontraumatic-angiographically-negative-subarachnoid-hemorrhage-a-retrospective-study-and-meta-analysis-of-the-literature
#6
Gelareh Sadigh, Chad A Holder, Jeffrey M Switchenko, Seena Dehkharghani, Jason W Allen
OBJECTIVE Diagnostic algorithms for nontraumatic angiographically negative subarachnoid hemorrhage (AN-SAH) vary, and the optimal method remains subject to debate. This study assessed the added value of cervical spine MRI in identifying a cause for nontraumatic AN-SAH. METHODS Consecutive patients 18 years of age or older who presented with nontraumatic SAH between February 1, 2009, and October 31, 2014, with negative cerebrovascular catheter angiography and subsequent cervical MRI were studied. Patients with intraparenchymal, subdural, or epidural hemorrhage; recent trauma; or known vascular malformations were excluded...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28980809/elucidating-the-behavior-of-cyclic-volatile-methylsiloxanes-in-a-subarctic-freshwater-food-web-a-modeled-and-measured-approach
#7
Ingjerd S Krogseth, Emma Undeman, Anita Evenset, Guttorm N Christensen, Mick J Whelan, Knut Breivik, Nicholas A Warner
Cyclic volatile methylsiloxanes (cVMS) are used in personal care products and emitted to aquatic environments through wastewater effluents, and their bioaccumulation potential is debated. Here, a new bentho-pelagic version of the ACC-HUMAN model was evaluated for polychlorinated biphenyls (PCBs) and applied to cVMS in combination with measurements to explore their bioaccumulation behavior in a subarctic lake. Predictions agreed better with measured PCB concentrations in Arctic char (Salvelinus alpinus) and brown trout (Salmo trutta) when the benthic link was included than in the pelagic-only model...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28962950/transoral-decompression-and-stabilization-of-the-upper-cervical-segments-of-the-spine-using-custom-made-implants-in-various-pathologic-conditions-of-the-craniovertebral-junction
#8
Alexey N Shkarubo, Alexander A Kuleshov, Ilia V Chernov, Marchel S Vetrile, Igor N Lisyansky, Sergey N Makarov, George P Ponomarenko, Michael Spyrou
BACKGROUND: Surgical treatment of patients with atlantoaxial instability caused by pathologic changes of the skull base and craniovertebral junction combined with anterior compression of the brain stem is still associated with substantial technical difficulties and remains a matter of debate. Currently, anterior stabilization of the atlantoaxial junction is a promising approach that allows for the resection of the pathologic lesion of the skull base and craniovertebral junction with subsequent stabilization of C1-C2 or C1-C3 in 1 stage...
September 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28962908/should-long-segment-cervical-fusions-be-routinely-carried-into-the-thoracic-spine-a-multicenter-analysis
#9
Eeric Truumees, Devender Singh, Matthew J Geck, John K Stokes
BACKGROUND CONTEXT: Although recommendations for caudal "end level" in posterior cervical reconstruction remain highly variable, the benefits of routine extension of posterior cervical fusions into the thoracic spine remain unclear. PURPOSE: We compared clinical and radiographic outcomes in patients in whom posterior fusions ended in the cervical spine versus those in whom the fusion was extended into the thoracic spine. STUDY DESIGN/SETTING: A multicenter retrospective analysis of prospectively followed patients was carried out...
September 28, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28915316/plate%C3%A2-pattern-clarification-of-the-marine-dinophyte-heterocapsa-triquetra-sensu-stein-dinophyceae-collected-at-the-kiel-fjord-germany
#10
Urban Tillmann, Mona Hoppenrath, Marc Gottschling, Wolf-Henning Kusber, Malte Elbrächter
One of the most common marine dinophytes is a species known as Heterocapsa triquetra. When Stein introduced the taxon Heterocapsa, he formally based the type species H. triquetra on the basionym Glenodinium triquetrum. The latter was described by Ehrenberg and is most likely a species of Kryptoperidinium. In addition to that currently unresolved nomenclatural situation, the thecal plate composition of H. triquetra sensu Stein (1883) was controversial in the past. To clarify the debate, we collected material and established the strain UTKG7 from the Baltic Sea off Kiel (Germany, the same locality as Stein had studied), which was investigated using light and electron microscopy, and whose systematic position was inferred using molecular phylogenetics...
September 15, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/28904564/the-role-of-pre-reduction-mri-in-the-management-of-complex-cervical-spine-fracture-dislocations-an-ongoing-controversy
#11
Sergiu Botolin, Todd F VanderHeiden, Ernest E Moore, Herbert Fried, Philip F Stahel
BACKGROUND: Cervical spine fracture-dislocations in neurologically intact patients represent a surgical challenge due to the risk of inflicting iatrogenic spinal cord compression by closed reduction maneuvers. The use of MRI for early advanced imaging in these injuries remains controversially debated. CASE PRESENTATION: A 54-year old man sustained a fall over the handlebars of his racing bicycle. The helmeted patient sustained a fall on his head which resulted in a hyperflexion injury of the neck...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28890222/identifying-subsets-of-patients-with-single-level-degenerative-disc-disease-for-lumbar-fusion-the-value-of-prognostic-tests-in-surgical-decision-making
#12
Victor E Staartjes, Pieter-Paul A Vergroesen, Dick J Zeilstra, Marc L Schröder
BACKGROUND CONTEXT: Fusion surgery for degenerative disc disease (DDD) has become a standard of care, albeit not without controversy. Outcomes are inconsistent and a superiority over conservative treatment is debatable. Proper patient selection is key to clinical success, and a comprehensive understanding of prognostic tests does not currently exist. PURPOSE: To investigate the value of prognostic tests and sociodemographic factors in predicting outcomes following lumbar fusion surgery for DDD...
September 7, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28838807/skeletal-health-in-breast-cancer-survivors
#13
REVIEW
Olivier Bruyère, Pierre Bergmann, Etienne Cavalier, Evelien Gielen, Stefan Goemaere, Jean-Marc Kaufman, Serge Rozenberg, Jean-Jacques Body
Although some risk factors for breast cancer might be protective for osteoporosis, several cross-sectional studies have reported, nevertheless, that patients with breast cancer have a lower bone mass and potentially a higher incidence of fractures than expected. In any case, it appears that patients with breast cancer are not protected from osteoporosis, which provides further support for the recommendation that bone health is assessed after a diagnosis of breast cancer. Most adjuvant therapies will lead to increased bone loss and a higher fracture rate...
November 2017: Maturitas
https://www.readbyqxmd.com/read/28755918/indeterminate-dendritic-cell-tumor-in-thoracic-spine-a-case-report-and-review-of-literature
#14
Sze Kiat Tan, Lee Onn Chieng, Karthik Madhavan, Andrew Rosenberg, Ian Cote
Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematological disorder with poorly understood pathogenesis. Occasionally encountered by hematologists, unusual presentations of IDCT have never been reported in the spine literature. The authors report a case of a 51-year-old man who presented with progressively worsening axial thoracic back pain radiating to his sides for three months. MRI revealed a large 3-cm enhancing mass at the T9 vertebral body with an exophytic component causing significant canal stenosis...
July 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28690777/hemangiopericytoma-of-the-thoracic-spine-a-case-report
#15
Luen Shaun Chew, Xinguang Julian Han, Kheng Kooi Tan, Manish Mahadeorao Bundele
Hemangiopericytoma (HPC) has been described to be aggressive and potentially a malignant tumour. We report a rare case of a 63-year-old Chinese male who presented with primary intradural extramedullary HPC of the thoracic spine. The main presenting complaint was gradual progression of back pain, associated with paraparesis and sensory deficit of lower limbs. He had MRI thoracolumbar with contrast which showed T9 lesion compressing on spinal cord and oedema, he was then operated upon and histopathology report confirmed a thoracic spine HPC...
July 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28689877/a-10-year-follow-up-of-bone-mineral-density-in-hiv-infected-youths-receiving-tenofovir-disoproxil-fumarate
#16
Vania Giacomet, Katia Maruca, Alessandro Ambrosi, Gian Vincenzo Zuccotti, Stefano Mora
BACKGROUND: The use of tenofovir disoproxil fumarate (TDF) has simplified the antiretroviral regimen for HIV-infected patients and improved their compliance with treatment, but it has been associated with decreased bone mineral density (BMD) in adult patients, and data in pediatric patients are debated. The aim of the current study was to assess the long-term effect of TDF on BMD in young patients. METHODS: BMD was measured at the lumbar spine and in the whole skeleton in 26 HIV-infected youths (13 female and 13 male, aged 5 to 17 years at baseline)...
July 6, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28681429/spiny-keratoderma-case-series-and-review
#17
Shien-Ning Chee, Ludi Ge, Nita Agar, Patricia Lowe
BACKGROUND: Spiny keratoderma is a rare, possibly under-reported, condition characterized by discrete keratotic plugs arising from the palms, soles, or both. It has been associated with malignancies though there is debate as to whether spiny keratoderma is a true paraneoplastic phenomenon. It has also been linked to a variety of non-neoplastic conditions, and several cases appear to be familial. METHODS: We describe two additional cases of this rare entity and review the literature...
July 5, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28557903/functional-recovery-following-early-kyphoplasty-versus-conservative-management-in-stable-thoracuolumbar-fractures-in-parachute-jumpers-a-randomized-clinical-trial
#18
Mohammad S Masoudi, Ali Haghnegahdar, Fariborz Ghaffarpasand, Ghazal Ilami
STUDY DESIGN: A randomized clinical trial. OBJECTIVE: To compare the functional recovery between early kyphoplasty and conservative care in paratroopers with stable thoracolumbar fractures. SUMMARY OF BACKGROUND DATA: Treatment of traumatic stable thoracolumbar fractures in young individuals is still a debate. Conservative management and kyphoplasty are options of therapy. But enough data are not available for supporting each. METHODS: We included 70 paratroopers with stable thoracolumbar fractures (A1 and A2 classification according to AOSpine thoracolumbar spine injury classification system) presenting <60 days after trauma and hyperintensity in T2-weighted magnetic resonance imaging...
May 26, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525481/comparison-of-the-clinical-and-radiographic-results-between-cervical-artificial-disk-replacement-and-anterior-cervical-fusion-a-6-year-prospective-nonrandomized-comparative-study
#19
Wei Tian, Kai Yan, Xiao Han, Jie Yu, Peihao Jin, Xiaoguang Han
STUDY DESIGN: Prospective nonrandomized comparative study. OBJECTIVE: To compare the long-term clinical and radiographic results of cervical artificial disk replacement (CADR) and anterior cervical discectomy and fusion (ACDF), and to provide our evidence if CADR could reduce adjacent segment degeneration (ASD). SUMMARY OF BACKGROUND DATA: CADR is widely used in spine surgery today. Despite the short-term results of it having been ascertained, the long-term results are still under observation...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28472336/association-of-hospitalization-for-neurosurgical-operations-in-magnet-hospitals-with-mortality-and-length-of-stay
#20
Symeon Missios, Kimon Bekelis
BACKGROUND: The association of Magnet hospital status with improved surgical outcomes remains an issue of debate. OBJECTIVE: To investigate whether hospitalization in a Magnet hospital is associated with improved outcomes for patients undergoing neurosurgical operations. METHODS: A cohort study was executed using all patients undergoing neurosurgical operations in New York registered in the Statewide Planning and Research Cooperative System database from 2009 to 2013...
May 3, 2017: Neurosurgery
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