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https://www.readbyqxmd.com/read/28425771/review-of-stereotactic-radiosurgery-for-intradural-spine-tumors
#1
Taylor E Purvis, C Rory Goodwin, Daniel Lubelski, Ilya Laufer, Daniel M Sciubba
Stereotactic radiosurgery (SRS) has become an increasingly popular treatment modality for spinal tumors due to its noninvasive and targeted approach. Whether SRS has the promise of relieving pretreatment symptoms and providing local tumor control for patients with intradural spine tumors is still debated. This review explores the current literature on SRS treatment for both metastatic and benign intradural tumors, with a focus on differential use for intramedullary and intradural extramedullary neoplasms. Although mortality rates from underlying malignant disease remain high, SRS may benefit patients with spinal metastatic lesions...
April 2017: CNS Oncology
https://www.readbyqxmd.com/read/28414168/decompression-alone-versus-fusion-for-pyogenic-spondylodiscitis
#2
Sung Hyun Noh, Ho Yeol Zhang, Hyun Sun Lim, Hyeon Jin Song, Kyung Hwa Yang
BACKGROUND CONTEXT: A spinal infection is a serious problem for a spine surgeon, and there is currently much debate regarding how best to treat pyogenic spondylodiscitis using antibiotics and the instrumentations that have been developed to date. PURPOSE: The purpose of this study was to determine which is better method for treating pyogenic spondylodiscitis. STUDY DESIGN/SETTING: A retrospective chart review was performed. PATIENT SAMPLE: Thirty-one patients with pyogenic spondylodiscitis underwent surgical treatment between 2000 and 2016 at the authors' institution...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28412560/comparison-of-minimally-invasive-spine-surgery-using-intraoperative-computed-tomography-integrated-navigation-fluoroscopy-and-conventional-open-surgery-for-lumbar-spondylolisthesis-a-prospective-registry-based-cohort-study
#3
Meng-Huang Wu, Navneet Kumar Dubey, Yen-Yao Li, Ching-Yu Lee, Chin-Chang Cheng, Chung-Sheng Shi, Tsung-Jen Huang
BACKGROUND CONTEXT: Till date, the surgical approaches for the treatment of lumbar spondylolisthesis by transforaminal lumbar interbody fusion (TLIF) using minimally invasive spine surgery assisted with intraoperative CT image-integrated navigation (MISS-iCT), fluoroscopy (MISS-FS) and conventional open surgery (OS) are debatable. PURPOSE: This study compared TLIF using MISS-iCT, MISS-FS and OS for treatment of one-level lumbar spondylolisthesis. STUDY DESIGN: This is a prospective registry-based cohort study which compared surgical approaches for patients who underwent surgical treatment for one-level lumbar spondylolisthesis...
April 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28409074/c2-and-greater-occipital-nerve-the-anatomic-and-functional-implications-in-spinal-surgery
#4
M Burhan Janjua, Peter L Zhou, Jeffrey P Greenfield, Ali A Baaj, Anthony Frempong-Boadu
INTRODUCTION: Posterior C1-C2 fusion is a highly successful treatment for atlantoaxial instability and other pathologies of the cervical spine, with fusion rates approaching 95%-100%. However, poor visualization of the lateral masses of C1 secondary to the course of the C2 nerve root along with blood loss from the venous plexus and compression of the C2 nerve from lateral mass screws are technical obstacles that can arise during surgery. Thus, sacrifice of the C2 nerve root has long since been debated in fusions involving the C1 and C2 vertebral bodies...
March 3, 2017: Curēus
https://www.readbyqxmd.com/read/28371053/nanoparticulate-tio2-mediated-inhibition-of-the-wnt-signaling-pathway-causes-dendritic-development-disorder-in-cultured-rat-hippocampal-neurons
#5
Fashui Hong, Yuguan Ze, Yaoming Zhou, Jie Hong, Xiaohon Yu, Lei Sheng, Ling Wang
Titanium dioxide nanoparticles (TiO2 NPs) are increasingly used in daily life, in industry and in environmental clearing, but their potential neurodevelopmental toxicity has been highly debated. In this study, we explored whether TiO2 NPs inhibited development of dendritic morphology and identified possible molecular mechanisms associated with this inhibition in primary cultured rat hippocampal neurons. Results showed that TiO2 NPs decreased neurite length, the number of branches and the spine density, and impaired mitochondrial function in the developing neurons...
March 28, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28368989/intraoperative-computed-tomography-versus-3d-c-arm-imaging-for-navigated-spinal-instrumentation
#6
Nils Hecht, Hadya Yassin, Marcus Czabanka, Bettina Föhre, Klaus Arden, Thomas Liebig, Peter Vajkoczy
STUDY DESIGN: A prospective case-series study and a retrospective analysis of historical patients for comparison of data. OBJECTIVE: To compare accuracy and limitations of intraoperative computed tomography (iCT)- versus 3D C-arm-based spinal navigation for posterior pedicle screw implantation. SUMMARY OF BACKGROUND DATA: Despite the higher accuracy of navigated compared to non-navigated pedicle screw implantation, it remains a matter of debate whether the use of iCT imaging may further benefit navigated spinal instrumentation compared to more commonly used isocentric 3D C-arm imaging...
March 31, 2017: Spine
https://www.readbyqxmd.com/read/28361330/the-paradox-of-bone-formation-and-bone-loss-in-ankylosing-spondylitis-evolving-new-concepts-of-bone-formation-and-future-trends-in-management
#7
REVIEW
Marina N Magrey, Muhammad A Khan
PURPOSE OF REVIEW: The purpose of the study is to briefly review the molecular mechanisms that leads to structural damage in ankylosing spondylitis (AS), defined as new bone formation resulting in complete or incomplete ankylosis of the spine, and the impact of treatment with biologics to retard this process. RECENT FINDINGS: The understanding of molecular mechanisms leading to new bone formation in AS has significantly improved but is still incomplete. Availability of biologics has greatly enhanced the treatment of patients with AS, but its impact on slowing the structural damage is still a matter of debate, although a few observational studies have shown that long term use of TNF-α blockers may slow radiographic progression...
April 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28219354/relationship-between-facet-tropism-and-facet-joint-degeneration-in-the-sub-axial-cervical-spine
#8
Xin Rong, Ziyang Liu, Beiyu Wang, Xuelin Pan, Hao Liu
BACKGROUND: Facet tropism is the angular asymmetry between the left and right facet joint orientation. Although debatable, facet tropism was suggested to be associated with disc degeneration, facet degeneration and degenerative spondylolisthesis in the lumbar spine. The purpose of this study was to explore the relationship between facet tropism and facet degeneration in the sub-axial cervical spine. METHODS: A total of 200 patients with cervical spondylosis were retrospectively analyzed...
February 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28150051/atypical-presentation-of-a-cervical-synovial-cyst
#9
Daniela Linhares, João Lobo, Rui Pinto, Nuno Neves
INTRODUCTION: Synovial cysts of the cervical spine are rare. These lesions have been associated with other spinal conditions as osteoarthritis, spondylolisthesis, and disc degeneration, with authors postulating a possible link with segmental spinal instability. This study aims to describe an atypically presenting case of a cervical synovial cyst. CASE REPORT: A 65-year-old man presented with complaints of cervical radicular pain (VAS of 7) that evolved with development of paresthesia and muscular weakness, compatible with C8 right compression...
February 1, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28149141/are-transitional-vertebra-and-spina-bifida-occulta-related-with-lumbar-disc-herniation-and-clinical-parameters-in-young-patients-with-chronic-low-back-pain
#10
Emine Eda Kurt, Aysegul Kuçukali Turkyilmaz, Yeliz Dadali, Hatice Rana Erdem, Figen Tuncay
OBJECTIVE: Lumbosacral transitional vertebra (LSTV) and spina bifida occulta (SBO) are widespread within the lumbosacral spine. Their connection to lumbar disc herniation (LDH) and/or lower back pain has been debated in the current literature; however, there is no consensus. The purpose of this study is to evaluate the relationship between the frequency of LSTV and SBO with that of LDH among young patients with chronic lower back pain. STUDY DESIGN: Cross-sectional...
October 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28118694/musculoskeletal-disorders-of-the-upper-cervical-spine-in-women-with-episodic-or-chronic-migraine
#11
Gabriela N Ferracini, Lidiane L Florencio, Fabíola Dach, Débora Bevilaqua Grossi, María Palacios-Ceña, Carlos Ordás-Bandera, Thais C Chaves, José G Speciali, César Fernández-DE-Las-Peñas
BACKGROUND: The role of musculoskeletal disorders of the cervical spine in migraine is under debate. AIM: To investigate differences in musculoskeletal impairments of the neck including active global and upper cervical spine mobility, the presence of symptomatic upper cervical spine joints, cervicocephalic kinesthesia and head/neck posture between women with episodic migraine, chronic migraine, and controls. DESIGN: A cross-sectional study...
January 24, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28089837/direct-midline-posterior-corpectomy-and-fusion-of-a-lumbar-burst-fracture-with-retrospondyloptosis
#12
Arthur Carminucci, Rachid Assina, R Nick Hernandez, Ira M Goldstein
BACKGROUND: Traumatic burst fractures of the lumbar spine can result in significant neurologic injury and mechanical instability. The ideal surgical approach for the treatment of unstable lumbar spine burst fractures remains debatable. CASE DESCRIPTION: A 37-year-old man presented with severe neurologic injury including loss of motor function below the level of the iliopsoas muscles bilaterally, saddle anesthesia, and absent rectal tone, after a fall from 18.28 m (60 ft)...
March 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28051824/atypical-femoral-fracture-as-first-sign-of-non-hodgkin-lymphoma-case-report-with-a-brief-review-of-the-literature
#13
REVIEW
G Saviola, P Prometti, P R Ferrari, L G Dalle Carbonare
ABSTRACT: Atypical subtrochanteric and diaphyseal femoral fractures (AFF) have been suggested to be associated with the use of bisphosphonates (BPs), but the role of these drugs is still under debate. A 64-year old female, never treated with BPs was admitted to our Rehabilitation Institute because of a recent right AFF. The patient began suffering from low back pain radiating to the groin and to the anterior regions of the right thigh and leg, A nuclear magnetic resonance (NMR) of the lumbar spine showed disc protrusions at the L3-L4 and L5-S1 levels with impingement of the spinal nerve root...
November 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27994792/prevalence-of-high-riding-vertebral-artery-and-morphometry-of-c2-pedicles-using-a-novel-computed-tomography-reconstruction-technique
#14
Wiwat Wajanavisit, Thamrong Lertudomphonwanit, Praman Fuangfa, Pongsthorn Chanplakorn, Chaiwat Kraiwattanapong, Supaneewan Jaovisidha
STUDY DESIGN: Cross-sectional, matched-pair comparative study. PURPOSE: To determine whether a thin-sliced pedicular-oriented computed tomography (TPCT) scan reconstructed from an existing conventional computed tomography (CCT) scan is more accurate for identifying vertebral artery groove (VAG) anomalies than CCT. OVERVIEW OF LITERATURE: Posterior atlantoaxial transarticular screw fixation and C2 pedicle screws can cause vertebral artery (VA) injury...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27994776/antimicrobial-prophylaxis-in-instrumented-spinal-fusion-surgery-a-comparative-analysis-of-24-hour-and-72-hour-dosages
#15
Chandrasekaran Marimuthu, Vineet Thomas Abraham, Mirunalini Ravichandran, Rajamani Achimuthu
STUDY DESIGN: Prospective study. PURPOSE: To compare the efficacy of 24-hour and 72-hour antibiotic prophylaxis in preventing surgical site infections (SSIs). OVERVIEW OF LITERATURE: Antimicrobial prophylaxis in surgical practice has become a universally accepted protocol for minimizing postoperative complications related to infections. Although prophylaxis is an accepted practice, a debate exists with regard to the antibiotic type and its administration duration for various surgical procedures...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27992640/complications-associated-with-bone-morphogenetic-protein-in-the-lumbar-spine
#16
Daniel G Kang, Wellington K Hsu, Ronald A Lehman
Complications associated with the use of recombinant human bone morphogenetic protein in the lumbar spine include retrograde ejaculation, ectopic bone formation, vertebral osteolysis and subsidence, postoperative radiculitis, and hematoma and seroma. These complications are controversial and remain widely debated. This article discusses the reported complications and possible implications for the practicing spine surgeon. Understanding the complications associated with the use of recombinant human bone morphogenetic protein and the associated controversies allows for informed decision making by both the patient and the surgeon...
December 19, 2016: Orthopedics
https://www.readbyqxmd.com/read/27920614/spine-care-as-a-framework-for-the-chiropractic-identity
#17
REVIEW
Michael Schneider, Donald Murphy, Jan Hartvigsen
OBJECTIVE: The purpose of this commentary is to provide an argument for the role and identity of chiropractors as spine care providers within the context of the greater health care system. DISCUSSION: Surveys of the general public and chiropractors indicate that the majority of patients seek chiropractic services for back and neck pain. Insurance company utilization data confirm these findings. Regulatory and legal language found in chiropractic practice acts reveals that most jurisdictions define the chiropractic scope of practice as based on a foundation of spine care...
December 2016: Journal of Chiropractic Humanities
https://www.readbyqxmd.com/read/27885472/a-prospective-randomized-trial-comparing-anterior-cervical-discectomy-and-fusion-versus-plate-only-open-door-laminoplasty-for-the-treatment-of-spinal-stenosis-in-degenerative-diseases
#18
Yun-Qi Jiang, Xi-Lei Li, Xiao-Gang Zhou, Chong Bian, Han-Ming Wang, Jian-Ming Huang, Jian Dong
OBJECTIVE: For three or more involved cervical levels, there is a debate over which approach yields the best outcomes for the treatment of multilevel cervical degenerative disease. Our objective is to compare the radiological and clinical outcomes of two treatments for multilevel cervical degenerative disease: anterior cervical discectomy and fusion (ACDF) versus plate-only open-door laminoplasty (laminoplasty). METHODS: Patients were randomized on a 1:1 randomization schedule with 17 patients in the ACDF group and 17 patients in the laminoplasty group...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27864682/posterior-implant-removal-in-patients-with-thoracolumbar-spine-fractures-long-term-results
#19
A J Smits, L den Ouden, A Jonkergouw, J Deunk, F W Bloemers
PURPOSE: Debate remains whether posterior implants after thoracolumbar spine fracture stabilization should be removed routinely or only in symptomatic cases. Implant related problems might be resolved or even prevented but removal includes secondary risks. The aim of this study was to evaluate safety, patient satisfaction and quality of life after implant removal. METHODS: A retrospective cohort study was performed concerning 102 patients that underwent posterior implant removal after stabilization of a traumatic thoracolumbar fracture between 2003 and 2015...
November 18, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27792122/health-related-quality-of-life-and-care-giver-burden-following-spinal-fusion-in-children-with-cerebral-palsy
#20
Rachel DiFazio, Patricia Miller, Judith A Vessey, Brian Snyder
STUDY DESIGN: Prospective longitudinal cohort OBJECTIVE.: Evaluate changes in caregivers' perceptions of health related quality of life (HRQOL) and caregiver burden in children with severe cerebral palsy (CP) following spinal fusion. SUMMARY OF BACKGROUND DATA: Progressive scoliosis is common in non-ambulatory children with CP; the utility of spine fusion has been long debated and prospective evaluations of patient reported outcomes are limited. METHODS: Children 3-21 years old, GMFCS IV-V CP, scheduled for spine fusion were enrolled consecutively from September 2011-March 2014...
October 25, 2016: Spine
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