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JOURNAL ARTICLE
E Cheran, C Sharmila Rahale, P Divyabharathi, C Viswanathan, Lakshmi Narayanan
Studies were carried out to develop eco-friendly Packaging material for the extended shelf-life of food products. The current study sought to improve the coated bioactive film's hydrophobicity and antimicrobial properties by preparing active packaging based on biodegradable Poly Lactic Acid (PLA) containing 1 wt% Nanocellulose (NC) and various loadings of essential oil-prepared nanocomposites. Nanocellulose (NC) from Maize Cob was used as filler in the synthesis of nanopolymers enriched with Thyme oil, Cinnamon oil, clove oil, and Rosemary oil...
April 11, 2024: International Journal of Biological Macromolecules
#2
JOURNAL ARTICLE
Yijing Zhu, Taoqi Wu, Qianyu Hu, Wenze He, Yushi Zheng, Yongjian Xie, Qiong Rao, Xunyue Liu
Tetranychus urticae , a prominent pest mite in strawberry and vegetable cultivation in China, has developed escalating resistance due to extensive chemical pesticide application. Consequently, there is an urgent need to identify safe and efficacious methods to reduce resistance development. In this study, 38 commercially available plant essential oils (EOs) were screened for their acaricidal potential and ability to inhibit oviposition. The findings revealed that 13 EOs exhibited notable acaricidal activity, with lemon EO demonstrating the highest toxicity, followed by sage, patchouli, frankincense, lemongrass, palmarosa, and oregano EOs...
March 8, 2024: Plants (Basel, Switzerland)
#3
REVIEW
Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar-Bouza
The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, Malta, for the pesticide active substance clove oil are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009 of the European Parliament and of the Council. The conclusions for the amendment of approval were reached on the basis of the evaluation of the representative use of clove oil as a preharvest nematicide on tomatoes and cucumbers (permanent greenhouse use)...
April 2024: EFSA journal
#4
JOURNAL ARTICLE
Keerthana M, Parvathy Mohan Menon, George Priya Doss C, Chandrasekaran Natarajan
Tuberculosis (TB), a deadly infectious disease, is primarily caused by the bacterium Mycobacterium tuberculosis . The misuse of antibiotics has led to the development of drug resistance, prompting researchers to explore new technologies to combat multidrug-resistant Tuberculosis (MDR TB). Phospholipid-based nanotherapeutics, such as nanoemulsions, are gaining traction as they enhance drug solubility, stability, and bioavailability. Our study focuses on the interaction between Bovine Serum Albumin (BSA) and a drug-loaded nanoemulsion based on Eugenol...
April 15, 2024: Heliyon
#5
JOURNAL ARTICLE
Hanan R H Mohamed, Sawsan El-Shamy, Sherein S Abdelgayed, Rofida Albash, Haidan El-Shorbagy
Titanium dioxide nanoparticles (TiO2 -NPs) have found wide applications in medical and industrial fields. However, the toxic effect of various tissues is still under study. In this study, we evaluated the toxic effect of TiO2 -NP on stomach, liver, and kidney tissues and the amelioration effect of clove oil nanoemulsion (CLV-NE) against DNA damage, oxidative stress, pathological changes, and the apoptotic effect of TiO2 -NPs. Four groups of male mice were subjected to oral treatment for five consecutive days including, the control group, the group treated with TiO2 -NPs (50 mg/kg), the group treated with (CLV-NE) (5% of the MTD), and the group treated with TiO2 -NPs plus CLV-NE...
April 2, 2024: Scientific Reports
#6
JOURNAL ARTICLE
Gayathri JawaharJothi, Boomiraj Kovilpillai, Avudainayagam Subramanian, Jayabalakrishnan Raja Mani, Sudhir Kumar, Balaji Kannan, Sudhakaran Mani
An experimental study was conducted to assess the detrimental effect of ground-level ozone (O3 ) on garlic physiology and to find out appropriate control measures against ground-level O3 , at TNAU-Horticultural Research farm, Udhagamandalam. Elevated ground ozone levels significantly decreased garlic leaf chlorophyll, photosynthetic rate, stomatal conductance, total soluble solids and pungency. The garlic chlorophyll content was highest in ambient ozone level and lowest in elevated ozone@200 ppb, highest stomatal conductance was recorded in ambient ozone with foliar spray of 3%Panchagavya, and the lowest was observed in elevated ozone@200 ppb...
March 25, 2024: International Journal of Biometeorology
#7
JOURNAL ARTICLE
Yang Li, Boya Bian, Rongrong Tang, Kexin Zhang
In order to extend the shelf life of fruits and vegetables, a sodium alginate-sodium carboxymethyl cellulose composite film loaded with poly(vinyl alcohol) microcapsules was prepared in this paper. The optimal film substrate ratios were obtained after the response surface optimization. Poly(vinyl alcohol) microcapsules were prepared, clove essential oil was loaded into them to investigate the effects of microcapsules on the composite film properties, and the microcapsule composite film with the best overall performance was selected to be applied to blueberry preservation...
March 19, 2024: ACS Omega
#8
JOURNAL ARTICLE
Nicolas Fontenele Callipo Cunha, Luciana Betzler de Oliveira de Siqueira, Andreza Raposo Garcia, Igor Almeida Rodrigues, Ana Paula Dos Santos Matos, Eduardo Ricci Júnior, Mariana Sato de Souza Bustamante Monteiro
UNLABELLED: Cutaneous leishmaniasis (CL) is a vector-borne disease characterized by skin lesions that can evolve into high-magnitude ulcerated lesions. Thus, this study aimed to develop an innovative nanoemulsion (NE) with clove oil, Poloxamer® 407, and multiple drugs, such as amphotericin B (AmB) and paromomycin (PM), for use in the topical treatment of CL. METHODS: Droplet size, morphology, drug content, stability, in vitro release profile, in vitro cytotoxicity on RAW 264...
March 22, 2024: Acta Tropica
#9
JOURNAL ARTICLE
Manpreet Kaur, Shivani Sharma, Anu Kalia, Nitika Sandhu
Essential oils are highly complex volatile chemical compounds utilized for food preservation. The present study compares the antibacterial, and antibiofilm activities of essential oils (EOs) and their blends. Three EOs-basil, clove, and lemongrass-and their blends were evaluated against five food-borne bacterial pathogens. A concentration-dependent effect with maximum inhibition at minimum inhibitory concentration values was recorded while no synergistic activity was observed on blending of EOs. The mechanism of antibacterial action was identified as ROS burst, leakage of cytoplasmic content, and DNA degradation through fluorescence microscopy, electrical conductivity, and DNA cleavage studies...
March 20, 2024: International Microbiology: the Official Journal of the Spanish Society for Microbiology
#10
JOURNAL ARTICLE
Stabak Das, Sudip Das, Sanjib Bahadur, Maitreyee Mukherjee, Gouranga Nandi, Sreejan Manna
The aim of this study was to develop and evaluate the transdermal patch formulations of nifedipine. The patch formulations containing nifedipine were prepared and optimized with different ratios of vinyl and cellulose-derived polymers, drug contents, and permeation enhancers. Among the various formulations, the patch formulation containing a 1:5 ratio of ethyl cellulose and polyvinyl pyrrolidone was selected for ex vivo pharmacokinetic study based on in vitro permeation studies using stratum corneum of the pig's skin...
March 19, 2024: Journal of Biomaterials Science. Polymer Edition
#11
JOURNAL ARTICLE
Xiaochong Zhu, Jieyuan Wu, Shizhong Li, La Xiang, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang
Eugenol, the main component of essential oil from the Syzygium aromaticum clove tree, has great potential as an alternative bioresource feedstock for biosynthesis purposes. Although eugenol degradation to ferulic acid was investigated, an efficient method for directly converting eugenol to targeted natural products has not been established. Herein we identified the inherent inhibitions by simply combining the previously reported ferulic acid biosynthetic pathway and vanillin biosynthetic pathway. To overcome this, we developed a novel biosynthetic pathway for converting eugenol into vanillin, by introducing cinnamoyl-CoA reductase (CCR), which catalyzes conversion of coniferyl aldehyde to feruloyl-CoA...
March 19, 2024: Journal of Agricultural and Food Chemistry
#12
JOURNAL ARTICLE
Pavithra Jayasankar, Manjula M Awatiger, Rubina Mulla, Bhaskar Kurangi, Shahana Shahapuri, Deepa R Mane
Background Oral candidiasis is the most prevalent oral fungal infection, and existing antifungal agents have side effects such as drug intolerance, resistance, and toxicity. Herbal essential oils are emerging as an alternative therapeutic approach for treating fungal infections . Origanum vulgare ( O. vulgare ), commonly known as oregano, and Syzygium aromaticum ( S. aromaticum ), commonly known as clove, are known to have antifungal properties and are effective against fluconazole-resistant strains. A combination of essential oils has a synergistic effect and aids in achieving effective antifungal activity at sufficiently low concentrations, which could lead to reduced side effects and resistance...
February 2024: Curēus
#13
JOURNAL ARTICLE
Sheila Cristina Almeida Neves Mutran, Paulo Roberto de Carvalho-Filho, Mara Eliane Soares Ribeiro, Kelson do Carmo Freitas Faial, Rafael Rodrigues Lima, Roberta Souza D'Almeida Couto
Introduction: The use of natural products such as essential oils has been suggested due to their promising pharmacological effects and economic viability. This study aimed to determine hydrogenic potential (pH), titratable acidity (TA), and ion concentrations of five solutions containing essential oils (EO), when used as a EO-containing solutions, and evaluate ion concentrations, enamel surface loss, and morphology alterations in enamel. Materials and methods: The pH, TA, calcium (Ca), potassium (K), and sodium (Na) concentrations of five EO-containing solutions were measured...
2024: Frontiers in Chemistry
#14
REVIEW
Valentina Maggini, Giulia Semenzato, Eugenia Gallo, Alessia Nunziata, Renato Fani, Fabio Firenzuoli
The use of natural compounds to prevent and treat infective diseases is increasing its importance, especially in the case of multidrug-resistant (MDR) microorganisms-mediated infections. The drug resistance phenomenon is today a global problem, so it is important to have available substances able to counteract MDR infections. Syzygium aromaticum (L.) Merr. & L.M. Perry (commonly called clove) is a spice characterized by several biological properties. Clove essential oil (EO) consists of numerous active molecules, being eugenol as the principal component; however, other compounds that synergize with each other are responsible for the biological properties of the EO...
February 25, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#15
JOURNAL ARTICLE
Suzana Vidaković Knežević, Slobodan Knežević, Jelena Vranešević, Dubravka Milanov, Zoran Ružić, Nedjeljko Karabasil, Sunčica Kocić-Tanackov
Yersiniosis, one of the leading foodborne infections in the European Union, is caused by Yersinia enterocolitica. In this study, the antibacterial and antibiofilm effects of cinnamon ( Cinnamomum zeylanicum Nees), clove ( Syzygium aromaticum L.), oregano ( Origanum vulgare L.), rosemary ( Rosmarinus officinalis L.), thyme ( Thymus vulgaris L.), and winter savory ( Satureja montana L.) essential oils were investigated against Y. enterocolitica strains belonging to the bioserotype 4/O:3. Cinnamon essential oil showed the highest antibacterial activity, with an MIC value 0...
March 6, 2024: Foods (Basel, Switzerland)
#16
JOURNAL ARTICLE
Pascal Fabry, Sandra Weber, Jan Teipel, Elke Richling, Stephan G Walch, Dirk W Lachenmeier
Isoeugenol (2-methoxy-4-(1-propenyl)phenol) has been recently classified as possibly carcinogenic to humans (Group 2B) by the International Agency for Research on Cancer (IARC). This study conducted an analysis of isoeugenol in common herbs and spices, including basil, cinnamon, ginger, and nutmeg, using 1 H nuclear magnetic resonance (NMR) spectrometry. Additionally, over 1300 coffee samples were analysed by 1 H-NMR for isoeugenol, but it was not detected in any of the analysed samples. Various essential oils, including nutmeg, basil, clove, sweet flag, and ylang-ylang oils, were examined for isoeugenol content...
February 27, 2024: Foods (Basel, Switzerland)
#17
JOURNAL ARTICLE
Anam Aziz, Muhammad Zaman, Mahtab Ahmad Khan, Talha Jamshaid, Muhammad Hammad Butt, Huma Hameed, Muhammad Shafeeq Ur Rahman, Qurat-Ul-Ain Shoaib
Ticagrelor (TCG) is a BCS class IV antiplatelet drug used to prevent platelet aggregation in patients with acute coronary syndrome, having poor solubility and permeability. The goal of this study was to develop a self-nanoemulsifying drug delivery system (SNEDDS) of TCG to improve its solubility and permeability. The excipients were selected based on the maximum solubility of TCG and observed by UV spectrophotometer. Different combinations of oil, surfactant, and co-surfactant (1:1, 2:1, and 3:1) were used to prepare TCG-SNEDDS formulations, and pseudo-ternary phase diagrams were plotted...
March 5, 2024: ACS Omega
#18
JOURNAL ARTICLE
Juliana Junqueira Pinelli, Angélica Sousa Guimarães, Monique Suela Silva, Tatiana Silveira Junqueira de Moraes, Michelle Carlota Gonçalves, Roberta Hilsdorf Piccoli
Clostridium botulinum is a foodborne pathogen responsible for severe neuroparalytic disease associated with the ingestion of pre-formed toxin in food, with processed meats and canned foods being the most affected. Control of this pathogen in meat products is carried out using the preservative sodium nitrite (NaNO2 ), which in food, under certain conditions, such as thermal processing and storage, can form carcinogenic compounds. Therefore, the objective was to use nanoemulsified essential oils (EOs) as natural antimicrobial agents, with the aim of reducing the dose of NaNO2 applied in mortadella...
February 29, 2024: Foodborne Pathogens and Disease
#19
JOURNAL ARTICLE
Ruixuan Geng, Seong-Gook Kang, Kunlun Huang, Tao Tong
Photoaging, the primary cause of skin aging damage, results from chronic ultraviolet (UV) exposure, leading to dryness and wrinkle formation. Nutritional intervention has emerged as a practical approach for preventing and addressing the effect of skin photoaging. The primary aromatic compound isolated from clove oil, isoeugenol (IE), has antibacterial, anti-inflammatory, and antioxidant qualities that work to effectively restrict skin cancer cell proliferation. This investigation delved into the advantages of IE in alleviating skin photoaging using UVB-irradiated skin fibroblasts and female SKH-1 hairless mouse models...
February 7, 2024: Nutrients
#20
JOURNAL ARTICLE
Wei-Chieh Huang, Lan-Hsin Shu, Yu-Ju Kuo, Kevin Shu-Leung Lai, Chih-Wei Hsia, Ting-Lin Yen, Chih-Hsuan Hsia, Thanasekaran Jayakumar, Chih-Hao Yang, Joen-Rong Sheu
Platelets assume a pivotal role in the pathogenesis of cardiovascular diseases (CVDs), emphasizing their significance in disease progression. Consequently, addressing CVDs necessitates a targeted approach focused on mitigating platelet activation. Eugenol, predominantly derived from clove oil, is recognized for its antibacterial, anticancer, and anti-inflammatory properties, rendering it a valuable medicinal agent. This investigation delves into the intricate mechanisms through which eugenol influences human platelets...
February 8, 2024: International Journal of Molecular Sciences
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