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https://www.readbyqxmd.com/read/28749613/linked-selection-demography-and-the-evolution-of-correlated-genomic-landscapes-in-birds-and-beyond
#1
Reto Burri
Selection has a deep impact on the distribution of genetic diversity and population differentiation along the genome (the genomic landscapes of diversity and differentiation), reducing diversity and elevating differentiation not only at the sites it targets, but also at linked neutral sites. Fuelled by the high-throughput sequencing revolution, these genomic footprints of selection have been extensively exploited over the past decade with the aim to identify genomic regions involved in adaptation and speciation...
August 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28749596/climate-change-climate-justice-and-environmental-health-implications-for-the-nursing-profession
#2
Patrice K Nicholas, Suellen Breakey
PURPOSE: Climate change is an emerging challenge linked to negative outcomes for the environment and human health. Since the 1960s, there has been a growing recognition of the need to address climate change and the impact of greenhouse gas emissions implicated in the warming of our planet. There are also deleterious health outcomes linked to complex climate changes that are emerging in the 21st century. This article addresses the social justice issues associated with climate change and human health and discussion of climate justice...
July 27, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28749552/the-eigenvalue-problem-in-phase-space
#3
Leon Cohen
We formulate the standard quantum mechanical eigenvalue problem in quantum phase space. The equation obtained involves the c-function that corresponds to the quantum operator. We use the Wigner distribution for the phase space function. We argue that the phase space eigenvalue equation obtained has, in addition to the proper solutions, improper solutions. That is, solutions for which no wave function exists which could generate the distribution. We discuss the conditions for ascertaining whether a position momentum function is a proper phase space distribution...
July 27, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28749533/charmm-force-field-and-molecular-dynamics-simulations-of-protonated-polyethylenimine
#4
Titus Adrian Beu, Alexandra Farcaş
As a gene delivery vector, polyethylenimine (PEI) shows one of the highest transfection efficiencies, while effectively protecting DNA from enzyme degradation. The distinctive charge pattern of protonated PEI is widely considered responsible for fundamental process such as DNA condensation into PEI/DNA polyplexes (which are able to enter cells via endocytosis), proton sponge effect (which triggers the release of polyplexes from endosome), and release of DNA from polyplexes (to be further processed inside the nucleus)...
July 27, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28749532/contracted-schr%C3%A3-dinger-equation-in-quantum-phase-space
#5
Carol Frishberg, Leon Cohen
The phase space formulation of quantum mechanics is equivalent to standard quantum mechanics where averages are calculated by way of phase space integration as in the case of classical statistical mechanics. We derive the quantum hierarchy equations, often called the contracted Schrödinger equation, in the phase space representation of quantum mechanics which involves quasi-distributions of position and momentum. We use the Wigner distribution for the phase space function and the Moyal phase space eigenvalue formulation to derive the hierarchy...
July 27, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28749492/a-cobalt-nitrosyl-complex-with-a-hindered-hydrotris-pyrazolyl-borate-coligand-detailed-electronic-structure-and-reactivity-towards-dioxygen
#6
Kiyoshi Fujisawa, Shoko Soma, Haruka Kurihara, Hai T Dong, Max Bilodeau, Nicolai Lehnert
The cobalt-nitrosyl complex [Co(NO)(L3)] is supported by a highly hindered tridentate nitrogen ligand, hydrotris(3-tertiary butyl-5-isopropyl-1-pyrazolyl)borate (denoted as L3(-)), and shows a linear Co-N-O unit. This complex was prepared by the reaction of the potassium salt of L3(-) with the cobalt-nitrosyl precursor [Co(NO)2(tmeda)](BPh4) (tmeda = N,N,N,'N'-tetramethylethylenediamine). The obtained cobalt-nitrosyl complex as well as the corresponding products from the reaction with dioxygen, [Co(η(2)-O2N)(L3)] and [Co(η(2)-O2NO)(L3)], were characterised by X-ray crystallography and a number of spectroscopic methods including IR/far-IR, UV-Vis, and NMR spectroscopy...
July 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28749429/establishment-of-a-site-specific-tropospheric-model-based-on-ground-meteorological-parameters-over-the-china-region
#7
Chongchong Zhou, Bibo Peng, Wei Li, Shiming Zhong, Jikun Ou, Runjing Chen, Xinglong Zhao
China is a country of vast territory with complicated geographical environment and climate conditions. With the rapid progress of the Chinese BeiDou satellite navigation system (BDS); more accurate tropospheric models must be applied to improve the accuracy of navigation and positioning. Based on the formula of the Saastamoinen and Callahan models; this study develops two single-site tropospheric models (named SAAS_S and CH_S models) for the Chinese region using radiosonde data from 2005 to 2012. We assess the two single-site tropospheric models with radiosonde data for 2013 and zenith tropospheric delay (ZTD) data from four International GNSS Service (IGS) stations and compare them to the results of the Saastamoinen and Callahan models...
July 27, 2017: Sensors
https://www.readbyqxmd.com/read/28749378/compton-scatter-tomography-in-tof-pet
#8
Hamidreza Hemmati, Alireza Kamali-Asl, Mohammadreza Ay, Pardis Ghafarian
Scatter Coincidences contain hidden information about the activity distribution on the Positron Emission Tomography (PET) imaging system. However, in conventional reconstruction, the scattered data cause the blurring of images and thus are estimated and subtracted from detected coincidences. List mode format provides a new aspect to use Time of Flight (TOF) and energy information of each coincidence at the reconstruction process. In this study, a novel approach is proposed to reconstruct activity distribution using the scattered data on the PET system...
July 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28749375/towards-fast-online-intrafraction-replanning-for-free-breathing-stereotactic-body-radiation-therapy-with-the-mr-linac
#9
Charis Kontaxis, Gijsbert H Bol, Bjorn Stemkens, Markus Glitzner, Fieke M Prins, Linda G W Kerkmeijer, Jan J W Lagendijk, Bas W Raaymakers
The hybrid MRI-radiotherapy machines, like the MR-linac (Elekta AB, Stockholm, Sweden) installed at the UMC Utrecht (Utrecht, The Netherlands), will be able to provide real-time patient imaging during treatment. In order to take advantage of the system's capabilities and enable online adaptive treatments, a new generation of software should be developed, ranging from motion estimation to treatment plan adaptation. In this work we present a proof of principle adaptive pipeline designed for high precision Stereotactic Body Radiation Therapy (SBRT) suitable for sites affected by respiratory motion, like Renal Cell Carcinoma (RCC)...
July 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28749374/nitrogen-doped-rgo-co3o4-nanograin-cookies-highly-porous-and-robust-catalyst-for-removing-nitrophenol-from-waste-water
#10
Erum Pervaiz, Muhammad Syam Azher Virk, Zhang Bingxue, Congling Yin, Minghui Yang
Fabrication of nanograins with uniform morphology wrapped with reduced graphene oxide (RGO) in a designed fashion is critical for obtaining large surface, high porosity and efficient catalytic ability at mild conditions. Hybrid structures of metal oxides decorated on two dimensional (2D) RGO lacked interface and channels between individual grains and RGO. Present work merely focused the synthesis of RGO wrapped Co3O4 nanograins architecture in micron sized polyhedrons and the ability of reducing aromatic nitro compounds...
July 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28749373/dosimetric-evaluation-of-a-commercial-proton-spot-scanning-monte-carlo-dose-algorithm-comparisons-against-measurements-and-simulations
#11
Jatinder Saini, Dominic Maes, Alexander Egan, Stephen R Bowen, Sara St James, Martin Janson, Tony Wong, Charles Bloch
RaySearch Americas Inc. (NY) has introduced a commercial Monte Carlo dose algorithm (RS-MC) for routine clinical use in proton spot scanning. In this report, we provide a validation of this algorithm against phantom measurements and simulations in GATE/GEANT4 software package. We also compared the performance of RayStation analytical algorithm (RS-PBA) against the RS-MC algorithm. Methods: A beam model (G-MC) for spot scanning gantry at our proton center was implemented in the GATE software package. The model was validated against measurements in a water phantom and was used for benchmarking the RS-MC...
July 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28749365/discriminative-joint-feature-topic-model-with-dual-constraints-for-wce-classification
#12
Yixuan Yuan, Xiwen Yao, Junwei Han, Lei Guo, Max Q-H Meng
Wireless capsule endoscopy (WCE) enables clinicians to examine the digestive tract without any surgical operations, at the cost of a large amount of images to be analyzed. The main challenge for automatic computer-aided diagnosis arises from the difficulty of robust characterization of these images. To tackle this problem, a novel discriminative joint-feature topic model (DJTM) with dual constraints is proposed to classify multiple abnormalities in WCE images. We first propose a joint-feature probabilistic latent semantic analysis (PLSA) model, where color and texture descriptors extracted from same image patches are jointly modeled with their conditional distributions...
July 25, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28749364/bayesian-random-vector-functional-link-networks-for-robust-data-modeling
#13
Simone Scardapane, Dianhui Wang, Aurelio Uncini
Random vector functional-link (RVFL) networks are randomized multilayer perceptrons with a single hidden layer and a linear output layer, which can be trained by solving a linear modeling problem. In particular, they are generally trained using a closed-form solution of the (regularized) least-squares approach. This paper introduces several alternative strategies for performing full Bayesian inference (BI) of RVFL networks. Distinct from standard or classical approaches, our proposed Bayesian training algorithms allow to derive an entire probability distribution over the optimal output weights of the network, instead of a single pointwise estimate according to some given criterion (e...
July 25, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28749363/distributed-parametric-consensus-optimization-with-an-application-to-model-predictive-consensus-problem
#14
Xinli Shi, Jinde Cao, Wei Huang
In this paper, we study a special class of distributed convex optimization problems--distributed parametric consensus optimization problem (DPCOP), for which a two-stage optimization method including primal decomposition and distributed consensus is provided. Different from traditional distributed optimization problems driving all the local states to a common value, DPCOP aims to solve a system-wide problem with partial common parameters shared amongst local agents in a distributed way. To relax the restriction on the topology, a distributed projected subgradient method is applied in distributed consensus stage to achieve the consensus of local estimated parameters, while the subgradients can be obtained by solving a multiparametric problem locally...
July 25, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28749350/distributed-adaptive-binary-quantization-for-fast-nearest-neighbor-search
#15
Xianglong Liu, Zhujin Li, Cheng Deng, Dacheng Tao
Hashing has been proved an attractive technique for fast nearest neighbor search over big data. Compared to the projection based hashing methods, prototype based ones own stronger power to generate discriminative binary codes for the data with complex intrinsic structure. However, existing prototype based methods like Spherical Hashing (SPH) and K-Means Hashing (KMH) still suffer from the ineffective coding that utilizes the complete binary codes in a hypercube. To address this problem, we propose an adaptive binary quantization (ABQ) method that learns a discriminative hash function with prototypes associated with small unique binary codes...
July 24, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28749343/a-potential-based-inverse-spectral-method-to-non-invasively-localize-discordant-distributions-of-alternans-on-the-heart-from-the-ecg
#16
Jaume Coll-Font, Burak Erem, Dana H Brooks
T-wave alternans (TWA), defined as the beat-to-beat alternation in amplitude of the T-waves, has been shown to be linked to ventricular fibrillation (VF). However, current TWA tests have high sensitivity but low specificity in determining who is at risk. To overcome this limitation, it might be helpful to determine the spatial distribution of any regions on the heart that alternate in opposite phase. Understanding these spatial distributions in relation to the regular activation of the heart could help explain the mechanism for the genesis of VF and thus disambiguate the low specificity of TWA...
July 26, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28749291/detection-of-intranuclear-coccidiosis-in-tortoises-in-europe-and-china
#17
Ekaterina Kolesnik, Janosch Dietz, Kim O Heckers, Rachel E Marschang
Intranuclear coccidiosis of tortoises (TINC) has been described in association with systemic disease in various species of tortoises. TINC has been detected in numerous tortoises from the United States, but there are only a few reports from tropical tortoises in Germany and no reports from Asia. Using a real-time polymerase chain reaction assay, samples from 1,011 tortoises were screened for the presence of TINC. Samples originated from animals kept in captivity in Europe and in China. Coccidia were detected in a total of 27 chelonians (2...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749268/detection-of-bartonella-sp-in-deer-louse-flies-lipoptena-mazamae-on-gray-brocket-deer-mazama-gouazoubira-in-the-neotropics
#18
Ugo Souza, Bruno Dall'Agnol, Thais Michel, Anelise Webster, Guilherme Klafke, João Ricardo Martins, Carlos Benhur Kasper, Tatiane Campos Trigo, Ricardo Ott, Márcia Maria de Assis Jardim, José Reck
Louse flies or deer keds, Lipoptena spp., are widespread in Neotropical cervids, but the vector-borne pathogens of louse flies had only been previously reported in the Northern hemisphere. This is the first report of Bartonella spp. in deer louse flies (Lipoptena mazamae) in the neotropics collected from gray brocket deer ( Mazama gouazoubira ) in Southern Brazil. DNA from Bartonella sp. was detected in all 429 L. mazamae collected from 11 road-killed gray brocket deer. The same sequences of DNA of Bartonella spp...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749259/management-of-pododermatitis-with-an-orthotic-boot-in-a-southern-isabela-giant-tortoise-chelonoidis-vicina
#19
Lynnette Waugh, Jennifer D'Agostino, Gretchen A Cole, Alicia Hahn, Jonathan D Day
A 62-yr-old male Southern Isabela giant tortoise (Chelonoidis vicina) had a 1-yr history of chronic, reoccurring pododermatitis on the palmar surface of the left forelimb. Aggressive wound management was instituted and included surgical debridement, vacuum-assisted closure, and orthotic boot support during healing. A custom fabricated, carbon fiber clamshell Charcot Restraint Orthotic Walker walking boot was utilized to reduce focal pressure over the wound during weight bearing and promote a more normal gait...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749255/pharmacokinetics-of-orally-administered-voriconazole-in-african-penguins-spheniscus-demersus-after-single-and-multiple-doses
#20
Michael W Hyatt, Nathan P Wiederhold, William W Hope, Katharine E Stott
Aspergillosis is a common respiratory fungal disease in African penguins ( Spheniscus demersus ) under managed care, and treatment failures with itraconazole due to drug resistance are increasingly common, leading to recent use of voriconazole. Empirical dosing with voriconazole based on other avian studies has resulted in adverse clinical drug effects in penguins. The objective of this study was to determine oral voriconazole pharmacokinetics (PK) in African penguins (n = 18). Single and once daily multiple oral doses of 5 mg/kg voriconazole were evaluated with a 4-mo washout period between trials...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
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