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https://www.readbyqxmd.com/read/28806217/the-effect-of-ondansetron-on-acute-opioid-tolerance-in-patients-receiving-intrathecal-opioids-prior-to-cesarean-delivery
#1
Kevin C Greer, Abdullah S Terkawi, Siny Tsang, Priyanka Singla, Marcel E Durieux, Mohamed Tiouririne
BACKGROUND: Multiple animal studies suggest that ondansetron ameliorates opioid-induced hyperalgesia and tolerance. In this study, we aimed to determine if the administration of ondansetron prior to spinal anesthesia would have an effect on intrathecal opioid-induced acute opioid tolerance, postoperative pain, and analgesic requirements in patients undergoing cesarean delivery with spinal anesthesia. METHODS: Eighty-six patients undergoing elective cesarean delivery were recruited and randomly allocated to receive either 8 mg intravenous ondansetron (n = 44) or placebo (n = 42) in a prospective, double-blind design...
August 11, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28806092/comparable-outcomes-after-bucket-handle-meniscal-repair-and-vertical-meniscal-repair-can-be-achieved-at-a-minimum-2-years-follow-up
#2
Gilbert Moatshe, Mark E Cinque, Jonathan A Godin, Alexander R Vap, Jorge Chahla, Robert F LaPrade
BACKGROUND: Meniscal tears can lead to significant pain and disability, necessitating surgical treatment. Nondisplaced vertical tears are usually smaller in size and can be repaired in most cases; however, bucket-handle tears are usually larger and displaced, and the repair of these tears can be challenging. Purpose/Hypothesis: The purpose was to report the outcomes after inside-out vertical mattress suture meniscal repair of bucket-handle tears and to compare these outcomes with those of patients who underwent repair of nondisplaced vertical meniscal tears with a minimum of 2 years' follow-up...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28802773/active-physiotherapy-interventions-following-total-knee-arthroplasty-in-the-hospital-and-inpatient-rehabilitation-settings-a-systematic-review-and-meta-analysis
#3
REVIEW
Kate G Henderson, Jason A Wallis, David A Snowdon
BACKGROUND: Physiotherapy is a routine component of postoperative management following total knee arthroplasty (TKA). As the demand for surgery increases it is vital that postoperative physiotherapy interventions are effective and efficient. OBJECTIVES: Determine the most beneficial active physiotherapy interventions in acute hospital and inpatient rehabilitation for improving pain, activity, range of motion and reducing length of stay for adults who have undergone TKA...
February 1, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28800726/incidence-and-risk-factors-of-chronic-pain-following-hysterectomy-among-southern-jiangsu-chinese-women
#4
Chao Han, Zhijun Ge, Wenjie Jiang, Hailong Zhao, Tieliang Ma
BACKGROUND: Chronic post-surgical pain (CPSP) after hysterectomy has been recognized as a major clinical problem in the Western World. Reports on post-hysterectomy pain are relatively scarce in China. The aim of the current study was to prospectively investigate the incidence and the potential risk factors of CPSP at 3 months following hysterectomy in Chinese population. METHODS: We assessed and collected data on preoperative socio-demographic characteristics, preexisting pain, anxiety and depression, sexual satisfaction, intra-operative variables, and acute postoperative pain intensity in a cohort of 870 women undergoing hysterectomy...
August 11, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28799579/tramadol-hydrochloride-75-mg-dexketoprofen-25-mg-oral-fixed-dose-combination-in-moderate-to-severe-acute-pain-sustained-analgesic-effect-over-a-56-h-period-in-the-postoperative-setting
#5
A Montero Matamala, M Bertolotti, M P Contini, C Guerrero Bayón, A Nizzardo, I Paredes Lario, B Pizà Vallespir, S Scartoni, G Tonini, A Capriati, A Pellacani
Multimodal analgesia constitutes a common strategy in pain management. A tramadol hydrochloride 75 mg/dexketoprofen 25 mg oral fixed combination (TRAM/DKP 75 mg/25 mg) has been recently registered and released in Europe for the treatment of moderate-to-severe acute pain. This paper provides additional analyses on the results of two phase III clinical trials (DEX-TRA-04 and DEX-TRA-05) on postoperative pain to document its sustained effect. The analysis was applied to a modified intention-to-treat population (mITT, n = 933) of patients undergoing active treatment from the first dose, to assess the sustained effect of TRAM/DKP 75 mg/25 mg on pain intensity (PI-VAS 0-100) over 56 h from first drug intake...
June 2017: Drugs of Today
https://www.readbyqxmd.com/read/28793825/controlling-acute-pain-to-improve-the-quality-of-postoperative-pain-management-an-update-from-the-european-society-of-regional-anesthesia-meeting-held-in-maastricht-september-2016
#6
Jose De Andrés, Esther Pogatzki-Zahn, Frank Huygen, Edmund Neugebauer, William Fawcett
Improvement in postoperative pain management remains a global concern with a significant unmet need for patients. This was the focus of a 'Change Pain' session at the 35th European Society of Regional Anesthesia meeting (Maastricht, September 2016). Awareness of the size and nature of the problem is important to improve postoperative pain management strategies. Optimal treatment of acute pain should aim to avoid long-term sequelae such as the development of chronic pain disorders (e.g., phantom limb pain)...
August 10, 2017: Pain Management
https://www.readbyqxmd.com/read/28791424/-to-stent-or-not-to-stent-immediate-emergency-surgery-with-laparoscopic-radical-colectomy-with-cme-and-primary-anastomosis-is-feasible-for-obstructing-left-colon-carcinoma
#7
Salomone Di Saverio, Arianna Birindelli, Edoardo Segalini, Matteo Novello, Anna Larocca, Francesco Ferrara, Gian Andrea Binda, Marco Bassi
Great debate exists in the initial acute management of large bowel obstruction from obstructing left colon carcinoma. While endoscopic stenting is well established as the first approach in the setting of palliative care of patients with advanced metastatic disease as well as a bridge to elective surgery in elderly patients who have an increased risk of postoperative mortality (age >70 years and/or ASA status ≥3), controversies exist regarding oncological safety and long-term outcomes of endoscopic colonic stenting in younger patients and ESGE Guidelines do not recommend SEMS placement in patients <70 and fit for curative surgery...
August 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28791193/spinal-thoracic-extradural-angiolipoma-manifesting-as-acute-onset-of-paraparesis-case-report-and-review-of-literature
#8
Franz Jooji Onishi, Flavio Augusto Sekeff Salem, Diogo Luis de Melo Lins, Rafi Felicio Bauab Dauar, João Norberto Stavale
BACKGROUND: Angiolipomas are benign tumors most commonly found in the thoracic spine. They are composed of mature adipocytes and abnormal vascular elements that usually present with a slowly progressive course of neurological deterioration. CASE DESCRIPTION: A 35-year-old female, with a prior history of back pain, acutely developed paraparesis. When the thoracic magnetic resonance imaging (MRI) revealed a dorsal epidural mass at the T3-T5 level, she underwent a laminectomy for gross total excision of the lesion that proved to be an angiolipoma...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28790094/gallstone-ileus-of-the-duodenum-an-unexpected-presentation-of-bouveret-s-syndrome
#9
Neil Tindell, Kayla Holmes, David Marotta
This report describes a patient who presented with a large gallstone obstructing the duodenal bulb, with the chief complaint of acute on chronic abdominal pain. Classically, this is known as Bouveret's syndrome or a gallstone ileus of the duodenum. Our patient's current health status presented a challenge, with the presence of several comorbidities, particularly a large abdominal aortic aneurism. We chose an open procedure for this reason. The stone was removed through a laparotomy, and the cholecystoduodenal fistula that the stone used to pass into the small bowel was repaired...
August 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28770418/acute-vs-elective-paraesophageal-hernia-repair-endoscopic-gastric-decompression-allows-semi-elective-surgery-in-a-majority-of-acute-patients
#10
Andrea Wirsching, Moustapha A El Lakis, Kamran Mohiuddin, Agostino Pozzi, Michal Hubka, Donald E Low
BACKGROUND: Historically, patients presenting acutely with paraesophageal hernia and requiring urgent operation demonstrated inferior outcomes compared to patients undergoing elective repair. METHODS: A prospective IRB-approved database was used to retrospectively review 570 consecutive patients undergoing paraesophageal hernia repair between 2000 and 2016. RESULTS: Thirty-eight patients presented acutely (6.7%) and 532 electively. Acute presentation was associated with increased age (74 vs...
August 2, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28768259/prospective-controlled-study-of-invasiveness-and-post-aggression-metabolism-in-patients-undergoing-robotic-assisted-radical-prostatectomy
#11
Andreas Martinschek, Lisa Stumm, Manuel Ritter, Elmar Heinrich, Christian Bolenz, Lutz Trojan
OBJECTIVES: To evaluate in a prospective, controlled, nonrandomized study the surgical stress and acute-phase systemic response in robotic-assisted laparoscopic prostatectomy (RALP) compared to open radical retro-pubic prostatectomy (ORRP) by measuring humoral mediators. METHODS: Forty consecutive patients undergoing either RALP or ORRP were prospectively included to assess the extent of systemic response. Blood samples were collected before surgery (T1), at the time of prostatectomy (T2), at the time of wound closure (T3), and 12 h (T4), 24 h (T5), and 48 h (T6) after surgery, and assayed for interleukins (IL-6 and IL-10), C-reactive protein (CRP), and hemoglobin...
July 29, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28767611/pregabalin-can-decrease-acute-pain-and-postoperative-nausea-and-vomiting-in-hysterectomy-a-meta-analysis
#12
Yi-Ming Wang, Min Xia, Nan Shan, Ping Yuan, Dong-Lin Wang, Jiang-He Shao, Hui-Wen Ma, Lu-Lu Wang, Yuan Zhang
BACKGROUND: Whether the preoperative administration of pregabalin plays a beneficial role in controlling acute pain after hysterectomy is unknown. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to determine the efficacy and safety of the preoperative use of pregabalin to treat acute postoperative pain following hysterectomy. METHODS: In April 2017, a systematic computer-based search was conducted in the PubMed, EMBASE, Web of Science, Cochrane Library, and Google databases...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28759544/minimally-invasive-access-aortic-arch-surgery
#13
Nora Goebel, Daniel Bonte, Schahriar Salehi-Gilani, Ragi Nagib, Adrian Ursulescu, Ulrich F W Franke
OBJECTIVE: Median sternotomy is still the standard approach for aortic arch surgery. Minimally invasive techniques promise faster recovery with shorter hospital stay due to thoracic stability, reduced pain, and superior cosmetic results. However, safety is a concern in complex aortic surgery. The aim of our study was to demonstrate that aortic arch surgery via partial upper sternotomy is viable, safe, and equivalent to standard procedure both in terms of its safety and the risk of major adverse cardiac and cerebrovascular events...
July 28, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28757835/pain-relief-following-thoracic-surgical-procedures-a-literature-review-of-the-uncommon-techniques
#14
REVIEW
Tariq Alzahrani
Thoracic surgical procedures can be either thoracotomy or thoracoscopy. In thoracotomy, the incision could be either muscle-cutting or muscle-sparing incision. The posterolateral thoracotomy incision is used for most general thoracic surgical procedures. This incision, which involves division of the latissimus dorsi and serratus anterior muscles, affords excellent exposure of the thoracic cavity. However, it is associated with significant morbidity, including impaired pulmonary function, postoperative chest pain, and restricted arm and shoulder movement...
July 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28754406/antibiotic-use-in-2016-by-members-of-the-american-association-of-endodontists-report-of-a-national-survey
#15
Mark Germack, Christine M Sedgley, Wael Sabbah, Brian Whitten
INTRODUCTION: This study surveyed the antibiotic prescribing practices of endodontists, and data were compared with previous surveys conducted in 1994 and 1999. METHODS: A 17-question survey was sent via www.surveymonkey.com to 3000 active members of the American Association of Endodontists for responses about antibiotic prescribing practices and demographics. The data were analyzed using descriptive statistics, chi-square tests, and linear regression analyses...
July 25, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28753590/ectopic-abdominal-pregnancy-due-to-uterine-perforation-after-an-attempt-to-terminate-pregnancy-a-case-presentation
#16
Jónathan Hernández Núñez, Alexander Abreu Díaz, Ndivhuwo Michael Ndwambi, Fermín Luis Martínez
Secondary abdominal ectopic pregnancy is rare in clinical practice, but may lead to an increased maternal mortality. We present the case of a patient with an abdominal pregnancy secondary to a uterine perforation caused by a voluntary attempt to interrupt pregnancy that presented with nine weeks of abdominal pain and minimal vaginal bleeding which was mistakenly diagnosed as acute pelvic inflammatory disease, urinary tract infection, and post-abortion products of conception. Finally, the abdominal ultrasound test found an abdominal ectopic pregnancy...
July 17, 2017: Medwave
https://www.readbyqxmd.com/read/28751024/preoperative-pregabalin-or-gabapentin-for-acute-and-chronic-postoperative-pain-among-patients-undergoing-breast-cancer-surgery-a%C3%A2-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
REVIEW
Ajit S Rai, James S Khan, Jasneet Dhaliwal, Jason W Busse, Stephen Choi, P J Devereaux, Hance Clarke
BACKGROUND AND OBJECTIVE: Breast cancer surgery is associated with acute and chronic pain. We sought to systematically evaluate the effects of gabapentin and pregabalin on postoperative pain among patients undergoing breast cancer surgery. DATABASES AND DATA TREATMENT: We searched MEDLINE, EMBASE, CENTRAL, Web of Science, and ProQuest from the inception of each database to November 2015. We included studies enrolling adult patients undergoing breast cancer surgery who were randomly assigned to preoperative gabapentin or pregabalin versus placebo or active control and assessed acute (≤24 h) or chronic (≥2 months) pain...
June 9, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28749298/successful-management-of-cecal-perforation-and-focal-peritonitis-in-a-gorilla-gorilla-gorilla-gorilla
#18
Sarah R Therio, Liza I Dadone, Michael M Garner, Jason Arble, Charles J Lalonde, Thomas J Baesl, Mindy Siegel, John A Marta, Dirk P Pikaart, Matthew S Johnston
An 18-yr-old female Western lowland gorilla ( Gorilla gorilla gorilla) presented with acute-onset severe lethargy, bloody vaginal discharge, decreased appetite, and an abnormal posture. The gorilla was diagnosed with a ruptured cecal blind sac with severe adhesions to the right ovary. A typhlectomy and unilateral ovariectomy were performed. Histologic examination identified a severe transmural circumferential typhlitis with rupture and adhesions to the infundibulum and chronic typhlitis. Postoperative management included antibiotics, analgesics, short-term dietary modifications, and probiotics for suspect oral candidiasis...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28745784/clinical-research-of-different-analgesia-methods-on-perianesthetic-pain-of-patients-with-moderate-and-severe-craniocerebral-injury-who-have-emergency-operation
#19
Q Huang, H Xu, Q-S Xiao
OBJECTIVE: To compare the effects of two different analgesia methods on postoperative pain of patients with moderate and severe craniocerebral injury who had an emergency operation. PATIENTS AND METHODS: In this study, 64 patients who were treated in our hospital from January 2015 to January 2016 and diagnosed with acute craniocerebral injury, were consecutively selected. The patients were divided into the propofol total intravenous anesthesia group (the observation group) and the isoflurane intravenous-inhalation combined anesthesia group (the control group) randomly with 32 cases each...
July 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28744692/frequency-of-acute-longus-colli-tendinitis-on-ct-examinations
#20
John Boardman, Emanuel Kanal, Patrick Aldred, Joseph Boonsiri, Chijindu Nworgu, Feng Zhang
PURPOSE: We attempted to determine the frequency of acute longus colli tendinitis on diagnostic CT imaging performed at a large multicenter health care system. By correlating with the pre-imaging clinical information, we investigated which patient presentations should lead the radiologist to increased suspicion for this condition. METHODS: Images from a total of 8101 adult CT examinations of the neck and cervical spine performed over a 3-month period were evaluated by researchers independent of the original clinical report...
July 25, 2017: Emergency Radiology
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