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https://www.readbyqxmd.com/read/29141957/adherent-invasive-escherichia-coli-in-inflammatory-bowel-disease
#1
REVIEW
Carolina Palmela, Caroline Chevarin, Zhilu Xu, Joana Torres, Gwladys Sevrin, Robert Hirten, Nicolas Barnich, Siew C Ng, Jean-Frederic Colombel
Intestinal microbiome dysbiosis has been consistently described in patients with IBD. In the last decades, Escherichia coli, and the adherent-invasive E coli (AIEC) pathotype in particular, has been implicated in the pathogenesis of IBD. Since the discovery of AIEC, two decades ago, progress has been made in unravelling these bacteria characteristics and its interaction with the gut immune system. The mechanisms of adhesion of AIEC to intestinal epithelial cells (via FimH and cell adhesion molecule 6) and its ability to escape autophagy when inside macrophages are reviewed here...
November 15, 2017: Gut
https://www.readbyqxmd.com/read/29123578/the-role-of-adhesion-molecules-in-inflammatory-bowel-disease-in-children-assessment-of-the-possible-risk-of-cardiovascular-complications
#2
Aneta Trzeciak-Jędrzejczyk, Ryszard Makosiej, Michał Kolejwa, Ewa Głowacka, Elżbieta Czkwianianc
Introduction: Inflammatory bowel diseases (IBD) are chronic diseases that proceed with exacerbation and remission phases. Adhesion molecules play a significant role in inflammatory processes. The same adhesion molecules play an important role in atherogenesis. Aim: To assess the risk of atherosclerosis in IBD in children. Material and methods: The study included 40 patients with IBD (25 with Crohn's disease - CD and 15 with ulcerative colitis - UC) aged 4-17 years...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29123001/effective-remedy-for-encapsulating-peritoneal-sclerosis-with-ureteroileal-fistula
#3
Masataka Banshodani, Hideki Kawanishi, Sadanori Shintaku, Masahiro Yamashita, Misaki Moriishi, Shinichiro Tsuchiya
Encapsulating peritoneal sclerosis (EPS), treated with surgical enterolysis as a final option, may become refractory to surgical intervention due to intraperitoneal complications. We report the case of a 59-year-old man presenting with EPS who underwent enterolysis at the age of 50, following 15 years of peritoneal dialysis (PD) and peritonitis. During the patient's first surgery, complete surgical enterolysis could not be performed due to severe intestinal adhesions with a deteriorated/calcified small bowel...
November 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29118874/pharmacobezoar-an-unusual-cause-of-large-bowel-obstruction
#4
Rishitha Yelisetti, Areig Awad, Bushra Ambreen, Ritika Zijoo, Sara Wallach
Large bowel obstruction (LBO) is an abdominal emergency with high morbidity and mortality rates if left untreated. LBO is four to five times less frequent than small bowel obstruction (SBO) and the causes of LBO and SBO differ substantially. Colonic malignancy remains the most common cause of LBO (> 60%). Additional causes of LBO include entities such as diverticulitis, colonic volvulus, and adhesion. Herein we present a case of acute LBO caused by pharmacobezoar.
October 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29117026/the-american-association-for-the-surgery-of-trauma-severity-grade-is-valid-and-generalizable-in-adhesive-small-bowel-obstruction
#5
Martin D Zielinski, Nadeem N Haddad, Asad Choudhry, Matthew C Hernandez, Daniel C Cullinane, David Turay, Ji-Ming Yune, Salina Wydo, Kenji Inaba, D Dante Yeh, Therese M Duane, Andrea Pakula, Ruby Skinner, Jill Watras, Carlos J Rodriguez, Kenneth A Widom, John Cull, Julie Dunn, Eric A Toschlog, Valerie G Sams, John C Graybill
INTRODUCTION: The American Association for the Surgery of Trauma (AAST) anatomic severity grading system for adhesive small bowel obstruction (ASBO) was validated at a single institution. We aimed to externally validate the AAST ASBO grading system using the Eastern Association for the Surgery of Trauma (EAST) multi-institutional SBO prospective observational study. METHODS: Adults (age≥18) with (ASBO) were included. Baseline demographics, physiologic parameters (heart rate, blood pressure, respiratory rate), labs (lactate, hemoglobin, creatinine, leukocytosis), imaging findings, operative details, length of stay, and Clavien-Dindo complications were collected...
November 7, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29114386/suppression-of-inflammation-and-tissue-damage-by-a-hookworm-recombinant-protein-in-experimental-colitis
#6
Ivana B Ferreira, Darren A Pickering, Sally Troy, John Croese, Alex Loukas, Severine Navarro
Gastrointestinal parasites, hookworms in particular, have evolved to cause minimal harm to their hosts when present in small numbers, allowing them to establish chronic infections for decades. They do so by creating an immunoregulatory environment that promotes their own survival, but paradoxically also benefits the host by protecting against the onset of many inflammatory diseases. To harness the therapeutic value of hookworms without using live parasites, we have examined the protective properties of the recombinant protein anti-inflammatory protein (AIP)-1, secreted in abundance by hookworms within the intestinal mucosa, in experimental colitis...
October 2017: Clinical & Translational Immunology
https://www.readbyqxmd.com/read/29109724/actors-and-factors-in-the-resolution-of-intestinal-inflammation-lipid-mediators-as-a-new-approach-to-therapy-in-inflammatory-bowel-diseases
#7
REVIEW
Federica Ungaro, Federica Rubbino, Silvio Danese, Silvia D'Alessio
In the last few decades, the pathogenesis of inflammatory bowel disease (IBD) in genetically predisposed subjects susceptible to specific environmental factors has been attributed to disturbance of both the immune and non-immune system and/or to the imbalanced interactions with microbes. However, increasing evidences support the idea that defects in pro-resolving pathways might strongly contribute to IBD onset. The resolution of inflammation is now recognized as a dynamic event coordinated by specialized pro-resolving lipid mediators (LMs), which dampen inflammation-sustaining events, such as angiogenesis, release of pro-inflammatory cytokines, clearance of apoptotic cells, and microorganisms...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29102485/adhesive-internal-hernia-multidetector-ct-findings-and-clinical-relevance
#8
C-Y Lu, M Xu, J Lin, Y Chen, Y Gao, Z-F Wang, Z-W Zhao, J-J Song, H-F Que, J-J Ji
AIM: To review the clinical and multidetector computed tomography (MDCT) features of adhesive internal hernias (IHs) and to ascertain specific MDCT criteria to assist in the diagnosis of adhesive IHs and the early detection of intestinal strangulation. MATERIALS AND METHODS: Medical records and preoperative abdominal MDCT findings of 34 patients with surgically confirmed abdominal adhesive IHs were analysed retrospectively. RESULTS: The specific MDCT features of adhesive IHs included the following: dislocating and clustering of intestinal segments (100%); stretching and crowding of the mesenteric vessels (100%); presence of hernial orifice (88...
November 1, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29089710/case-report-intestinal-obstruction-as-a-late-presentation-of-perforation-of-the-transverse-colon-following-blunt-abdominal-trauma
#9
José Caballero, Cinthya Alva-Torres, Edwin García
Colonic perforation associated with blunt abdominal trauma is rare. Even more so is the formation of an inflammatory adhesion preventing leakage into the peritoneum. We present a case of the above in which the patient presented 1 month later with intestinal obstruction which required surgical intervention. A 38-year-old male, victim of a road traffic accident (RTA), presented with multiple fractures in his extremities which had to be operated on and was later discharged without complications. He was readmitted 1 month following the trauma with intestinal obstruction...
October 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29078904/surgeon-attitudes-and-practice-patterns-in-managing-small-bowel-obstruction-a-qualitative-analysis
#10
Lucas W Thornblade, Anjali R Truitt, Giana H Davidson, David R Flum, Danielle C Lavallee
BACKGROUND: Historical training instructs surgeons to, "never let the sun set on a small bowel obstruction (SBO)" due to concern for bowel ischemia. However, the routine use of computed tomography scans for ruling out ischemia provides the opportunity for trial of nonoperative management, allowing time for resolution of adhesive SBO. In light of advances in practice, little is known about how surgeons manage these patients, in particular, whether there is consistency in the stated duration for safe nonoperative management...
November 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29069002/the-long-term-outcomes-of-recurrent-adhesive-small-bowel-obstruction-after-colorectal-cancer-surgery-favor-surgical-management
#11
Kwan Mo Yang, Chang Sik Yu, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Jin Cheon Kim
An adhesive small bowel obstruction (ASBO) is generally caused by postoperative adhesions and is more frequently associated with colorectal surgeries than other procedures. We compared the outcomes of operative and conservative management of ASBO after primary colorectal cancer surgery.We retrospectively reviewed 5060 patients who underwent curative surgery for primary colorectal cancer; 388 of these patients (7.7%) were readmitted with a diagnosis of SBO. We analyzed the clinical course of these patients with reference to the cause of their surgery...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29066699/-a-case-of-roux-en-y-loop-reconstruction-using-a-modified-aboral-pouch-technique-for-y-limb-obstruction-following-distal-gastrectomy
#12
Kazuki Kano, Haruhiko Cho, Yukio Maezawa, Toru Aoyama, Tsutomu Hayashi, Takanobu Yamada, Tsutomu Sato, Takashi Oshima, Norio Yukawa, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Takaki Yoshikawa
A 53-year-old man underwentdistal gastrectomy with Roux-en-Y(R-Y)reconstruction for gastric cancer. An R-Y anastomosis was performed usinga 21mm circular stapler. Five years postoperatively, he visited our hospital with anorexia. An abdominal computed tomography scan showed dilatation of the afferent loop. He was diagnosed with afferent loop syndrome due to R-Y anastomotic stenosis that resulted in poor oral intake and malnutrition. A U-shaped bend created by an adhesion caused a bowel obstruction of the Y-anastomotic site for which the patient underwent R-Y loop reconstruction with an aboral pouch usinga 60mm linear stapler...
October 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29061321/robotic-parastomal-hernia-repair-with-biologic-mesh
#13
Peter Mekhail, Akbar Ashrafi, Mario Mekhail, David Hatcher, Monish Aron
INTRODUCTION: Parastomal hernia is a common and vexing problem after ileal conduit urinary diversion that can cause pain, bowel symptoms, and problems with the stoma appliance, resulting in leakage, odor, and impairment of quality of life. Historically, these hernias have been managed open surgically, which requires considerable dissection of the abdominal wall for mesh placement, and may also require relocating the stoma to the contralateral side. Further, open parastomal hernia repair can be a morbid procedure with recurrence rates of approximately 30%...
September 7, 2017: Urology
https://www.readbyqxmd.com/read/29059609/a-case-of-laparoscopy-assisted-vaginal-cuff-suturing-for-vaginal-cuff-dehiscence-after-total-laparoscopic-hysterectomy
#14
Tomoatsu Jimi, Rumiko Yamamoto, Koji Seo, Mari Matsuoka, Saori Hata, Yukiko Ando, Hiromi Miyata, Yuki Kozono, Natsuki Tsuji, Akiko Okuda, Kentaro Sekiyama, Koichi Terakawa, Tadayoshi Nagano
INTRODUCTION: Vaginal cuff dehiscence after hysterectomy is a rare complication and occurs in less than 1% of patients. It can present with serious complications, such as bowel evisceration and peritonitis. PRESENTATION OF CASE: A 51-year-old multigravida Korean woman underwent total laparoscopic hysterectomy for leiomyoma. Six months later, she reported lower abdominal pain and vaginal bleeding. Physical examination revealed rebound tenderness in the lower abdomen, and pelvic examination showed a small amount of vaginal bleeding with an evisceration of the small intestine through the vagina that exhibited healthy peristalsis...
October 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29046801/outcome-of-decompression-using-a-transnasal-ileus-tube-in-malignant-adhesive-bowel-obstruction-a-retrospective-study
#15
Xiang-Jun Han, Fan Zhao, Hong-Ying Su, Ke Xu
Malignant adhesive bowel obstruction caused by peritoneal carcinomatosis is a common complication of advanced abdominal malignancies, and surgical treatment provides little benefit. The present study was undertaken to evaluate the decompression efficacy of a transnasal ileus tube under X-ray guidance, with benign adhesive bowel obstruction patients serving as the control group. A total of 21 patients with malignant adhesive bowel obstruction and 60 patients with benign conditions were enrolled between February 2011 and March 2015...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29046094/ostomy-creation-with-fewer-sutures-using-tissue-adhesives-cyanoacrylates-in-inflammatory-bowel-disease-a-pilot-study
#16
M Uchino, H Ikeuchi, T Bando, H Sasaki, T Chohno, Y Horio, Y Takesue
Introduction Fistula formation around the ostomy site is a stoma-related complication often requiring surgical intervention. This complication may be caused by sutures or may develop as a complication of inflammatory bowel disease. Before conducting a clinical trial, we set out to investigate the safety of ostomy creation with fewer sutures using tissue adhesives in this pilot study. Methods Patients with inflammatory bowel disease who required surgery with ostomy creation at the Hyogo College of Medicine between January 2014 and December 2015 were enrolled...
October 19, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29045179/clinical-relevance-of-the-feces-sign-in-small-bowel-obstruction-due-to-adhesions-depends-on-its-location
#17
Wassef Khaled, Ingrid Millet, Lucie Corno, Isabelle Bouley-Coletta, Mohamed Amine Benadjaoud, Patrice Taourel, Marc Zins
OBJECTIVE: The objective of our study was to evaluate if the feces sign can be used to predict successful nonoperative treatment or progression to ischemia in patients with small-bowel obstruction (SBO) due to adhesions. MATERIALS AND METHODS: For this single-center retrospective observational study involving a blinded independent review by two radiologists of 237 consecutive CT examinations of 216 patients with SBO due to adhesions (age: mean, 70.9 years; median, 74 years; interquartile range, 62-84 years), the location of the transition zone (TZ), number of TZs, and presence and location of the feces sign relative to the TZ were recorded...
October 18, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29030779/recurrence-after-operative-treatment-of-adhesive-small-bowel-obstruction
#18
Lea Lorentzen, Mari N Øines, Erling Oma, Kristian K Jensen, Lars N Jorgensen
BACKGROUND: Postoperative adhesions are a common cause of small-bowel obstruction, and up to 53% of patients operated on for adhesive small-bowel obstruction (ASBO) experience recurrence. The primary aim of this study was to identify predictors for recurrence of ASBO. METHODS: We reviewed medical records including operation descriptions from patients who underwent emergency surgery due to ASBO at our institution between 2004 and 2013. Information on the peri- and postoperative periods, including conservatively and surgically treated recurrent ASBO, were obtained from medical records...
October 13, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29020699/the-first-homemade-colonoscopy-trainer
#19
Dominik Andrzej Walczak, Maciej Grajek, Paulina Agnieszka Walczak, Magdalena Tuliszka-Gołowkin, Roman Massopust, Dariusz Pawełczak, Zbigniew Pasieka, Łukasz Krakowczyk, Adam Maciejewski
Introduction Colonoscopy trainers have gained recognition for improving endoscopy skills and preparing for real procedures on humans. Unfortunately, due to their high price, commercial simulators are hard to obtain, especially for small medical centers. However, a solution might be to construct a device for themselves. Aim Our goal was to build a relatively cheap and easy-to-construct simulator for residents who want to start learning colonoscopy. Materials and methods The box model colonoscopy trainer was designed and constructed...
October 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29018940/laparoscopy-or-laparotomy-for-adhesive-bowel-obstruction-in-children-a-systematic-review-and-meta-analysis
#20
Hiromu Miyake, Shogo Seo, Agostino Pierro
PURPOSE: Adhesive small bowel obstruction (ASBO) is one of the most important cause of postoperative morbidity in children who underwent abdominal surgery. Laparoscopic management for ASBO in pediatric patients has been reported. However, its safety and efficacy has not been evaluated in details. The aim of this study is to compare the outcomes of laparoscopy and laparotomy for the treatment of ASBO in children. METHODS: A systematic review and meta-analysis were performed following the Cochrane Handbook for systematic reviews of intervention and the preferred reporting item for systematic reviews and meta-analysis (PRISMA) and a protocol registered in PROSPERO (CRD42017067914)...
October 10, 2017: Pediatric Surgery International
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