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https://www.readbyqxmd.com/read/28088711/surgery-for-chronic-mesh-infection-occurred-10-years-after-sacrectomy-mesh-resection-and-mesentric-leaf-repair-a-case-report
#1
Makoto Koyama, Yusuke Miyagawa, Yuta Yamamoto, Masato Kitazawa, Akira Suzuki, Satoshi Ishizone, Shinichi Miyagawa
INTRODUCTION: Sacrectomy to treat malignant tumors is often results in large pelvic defects to require reconstruction, using a prosthetic mesh. Importance is to avoid its direct contact of mesh with intestine to prevent adhesion between them. PRESENTATION OF CASE: An 83-year old woman who was diagnosed with a mesh infection caused by a small bowel penetration 10 years after sacrectomy combined with mesh reconstruction for chordoma. In the first operation, because of incomplete re-peritonealization due to a large defect in the retroperitoneum, a mesh unavoidably was compelled to contact with the small intestine...
October 26, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28087066/use-of-water-soluble-contrast-medium-gastrografin-does-not-decrease-the-need-for-operative-intervention-nor-the-duration-of-hospital-stay-in-uncomplicated-acute-adhesive-small-bowel-obstruction-a-multicenter-randomized-clinical-trial-adhesive-small-bowel-obstruction
#2
Michel Scotté, Francois Mauvais, Michael Bubenheim, Cyril Cossé, Leslie Suaud, Celine Savoye-Collet, Isabelle Plenier, Aurelien Péquignot, Thierry Yzet, Jean Marc Regimbeau
BACKGROUND: This study evaluated the association between oral gastrografin administration and the need for operative intervention in patients with presumed adhesive small bowel obstruction. METHODS: Between October 2006 and August 2009, 242 patients with uncomplicated acute adhesive small bowel obstruction were included in a randomized, controlled trial (the Adhesive Small Bowel Obstruction Study, NCT00389116) and allocated to a gastrografin arm or a saline solution arm...
January 10, 2017: Surgery
https://www.readbyqxmd.com/read/28076877/ultrasound-imaging-for-ovarian-and-deep-infiltrating-endometriosis
#3
Caterina Exacoustos, Errico Zupi, Emilio Piccione
The main challenges of imaging for endometriosis are the detection of nonovarian disease and the evaluation of the extension of the disease into pelvic structures. Transvaginal ultrasonography (TVS) has been proposed as the first-line imaging technique because it allows extensive exploration of the pelvis. The "typical" endometrioma is a unilocular cyst with homogeneous low-level echogenicity (ground glass echogenicity) of the cyst fluid. The use of color Doppler helps avoid classifying malignancies as endometriomas, defining the presence of vascular flow in papillations...
January 11, 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28051049/non-laparoscopic-minimal-surgical-approach-to-pyloromyotomy-an-experience-from-a-challenged-resource-setting
#4
Ossama M Zakaria
BACKGROUND: The aim of the study is to review the experience with the classic Ramstedt's pyloromyotomy through the RUQ approach and the circumlinear supraumbilical fold approach (circumumbilical [CU]) pyloromyotomy (an approach that combines the ease and safety of the open pyloromyotomy with the advantages of minimal invasiveness). PATIENTS AND METHODS: A single centre review in a period of 12 years from January 2001 to December 2013 with the institutional ethical committee's approval, evaluating 316 pyloromyotomies based on surgical approach: RUQ (171); and CU (145)...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28050471/spectrum-of-mdct-findings-in-bowel-obstruction-in-a-tertiary-care-rural-hospital-in-northern-india
#5
Ranjana Gupta, Puneet Mittal, Amit Mittal, Sharad Gupta, Kapish Mittal, Arpit Taneja
INTRODUCTION: Multidetector Computed Tomography (MDCT) provides clinically and surgically important information in bowel obstruction. It can depict the severity, level and cause of obstruction. AIM: To depict the spectrum of MDCT findings in cases of small and large bowel obstruction. MATERIALS AND METHODS: Contrast enhanced MDCT examination of 50 patients were retrospectively included in the study who had evidence of clinical as well as MDCT evidence of bowel obstruction and in whom surgical/clinical follow-up for final diagnosis was available...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28049834/aquaporin-3-mediates-hydrogen-peroxide-dependent-responses-to-environmental-stress-in-colonic-epithelia
#6
Jay R Thiagarajah, Jeffrey Chang, Jeremy A Goettel, Alan S Verkman, Wayne I Lencer
The colonic epithelium provides an essential barrier against the environment that is critical for protecting the body and controlling inflammation. In response to injury or gut microbes, colonic epithelial cells produce extracellular hydrogen peroxide (H2O2), which acts as a potent signaling molecule affecting barrier function and host defense. In humans, impaired regulation of H2O2 in the intestine has been associated with early-onset inflammatory bowel disease and colon cancer. Here, we show that signal transduction by H2O2 depends on entry into the cell by transit through aquaporin-3 (AQP3), a plasma membrane H2O2-conducting channel...
January 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28044949/sphincter-sparing-surgery-in-patients-with-mid-and-low-rectal-cancer-risk-factors-for-local-recurrence-and-anastomotic-leakage
#7
Denis Aslan, Florin Grama, Daniel Cristian, Adrian Bordea, Traean Burcoş
: Background: Rectal cancer is a major health problem. The current treatment of distal rectal cancer involves a multimodality approach aimed at achieving an optimal oncologic control and an increased quality of life. PURPOSE: The purpose of this article is to identify the risk factors for local recurrence and anastomotic leakage after sphincter-sparing surgery for low and mid rectal cancer. Material and Methods: We prospectively analyzed a group of 38 patients with low and middle rectal cancer who underwent sphincter-sparing surgery...
November 2016: Chirurgia
https://www.readbyqxmd.com/read/28039651/prevention-of-internal-hernias-and-pelvic-adhesions-following-laparoscopic-left-sided-colorectal-resection-the-role-of-fibrin-sealant
#8
Pierluigi Angelini, Antonio Sciuto, Diego Cuccurullo, Felice Pirozzi, Stefano Reggio, Francesco Corcione
BACKGROUND: Laparoscopy has increasingly become the standard of care for patients who undergo colorectal surgery for both benign and malignant diseases. This growing experience has also resulted in more reports of postoperative complications from the minimally invasive approach to primary colorectal resection. Small bowel obstruction from internal hernias and pre-sacral adhesions is an uncommon but not negligible complication. However, there is little literature specific to this topic with recommendations for different methods to prevent it...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28028380/small-bowel-obstruction-secondary-to-adhesions-after-open-or-laparoscopic-colorectal-surgery
#9
Sebastian Smolarek, Mostafa Shalaby, Giulio Paolo Angelucci, Giulia Missori, Ilaria Capuano, Luana Franceschilli, Silvia Quaresima, Nicola Di Lorenzo, Pierpaolo Sileri
BACKGROUND AND OBJECTIVES: Small-bowel obstruction (SBO) is a common surgical emergency that occurs in 9% of patients after abdominal surgery. Up to 73% are caused by peritoneal adhesions. The primary purpose of this study was to compare the rate of SBOs between patients who underwent laparoscopic (LPS) and those who had open (OPS) colorectal surgery. The secondary reasons were to evaluate the rate of adhesive SBO in a cohort of patients who underwent a range of colorectal resections and to assess risk factors for the development of SBO...
October 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28000487/risk-factors-for-post-colectomy-adhesive-small-bowel-obstruction
#10
Edin Husarić, Šefik Hasukić, Nešad Hotić, Amir Halilbašić, Senada Husarić, Ismar Hasukić
OBJECTIVE: The purpose of this study was to assess the risk factors for adhesive small bowel obstruction (SBO) following colectomy for colorectal cancer. PATIENTS AND METHODS: In this retrospective study we analyzed 284 patients who underwent surgery for colorectal cancer at the Department of Surgery University Clinical Center Tuzla in the period from 1st January 2009 until 31st December 2014. All patients underwent open colectomy. The length of follow up was from 6 months to 6 years (median follow up 3 years and 6 months)...
November 2016: Acta Medica Academica
https://www.readbyqxmd.com/read/27994454/the-role-of-the-intestinal-microvasculature-in-inflammatory-bowel-disease-studies-with-a-modified-caco-2-model-including-endothelial-cells-resembling-the-intestinal-barrier-in-vitro
#11
Jennifer Y Kasper, Maria Iris Hermanns, Christian Cavelius, Annette Kraegeloh, Thomas Jung, Rolf Danzebrink, Ronald E Unger, Charles James Kirkpatrick
The microvascular endothelium of the gut barrier plays a crucial role during inflammation in inflammatory bowel disease. We have modified a commonly used intestinal cell model based on the Caco-2 cells by adding microvascular endothelial cells (ISO-HAS-1). Transwell filters were used with intestinal barrier-forming Caco-2 cells on top and the ISO-HAS-1 on the bottom of the filter. The goal was to determine whether this coculture mimics the in vivo situation more closely, and whether the model is suitable to evaluate interactions of, for example, prospective nanosized drug vehicles or contrast agents with this coculture in a physiological and inflamed state as it would occur in inflammatory bowel disease...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27966058/surgical-considerations-in-the-treatment-of-small-bowel-crohn-s-disease
#12
Lillias Holmes Maguire, Karim Alavi, Ranjan Sudan, Paul E Wise, Andreas M Kaiser, Liliana Bordeianou
Surgery remains a cornerstone of the management of Crohn's disease (CD). Despite the rise of biologic therapy, most CD patients require surgery for penetrating, obstructing, or malignant complications. Optimal surgical therapy requires sophisticated operative judgment and medical optimization. Intraoperatively, surgeons must balance treatment of CD complications against bowel preservation and functional outcome. This demands mastery of multiple techniques for anastomosis and strictureplasty, accurate assessment of bowel integrity for margin minimization, and a comprehensive skillset for navigating adhesions and altered anatomy, controlling thickened mesentery, and safely managing the hostile abdomen...
December 13, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27942903/downregulation-of-cx3cr1-ameliorates-experimental-colitis-evidence-for-cx3cl1-cx3cr1-mediated-immune-cell-recruitment
#13
Felix Becker, Christina Holthoff, Christoph Anthoni, Emile Rijcken, J Steven Alexander, Felicity N E Gavins, H U Spiegel, Norbert Senninger, Thorsten Vowinkel
PURPOSE: Inflammatory conditions like inflammatory bowel diseases (IBD) are characterized by increased immune cell infiltration. The chemokine ligand CX3CL1 and its receptor CX3CR1 have been shown to be involved in leukocyte adhesion, transendothelial recruitment, and chemotaxis. Therefore, the objective of this study was to describe CX3CL1-CX3CR1-mediated signaling in the induction of immune cell recruitment during experimental murine colitis. METHODS: Acute colitis was induced by dextran sodium sulfate (DSS), and sepsis was induced by injection of lipopolysaccharide (LPS)...
December 10, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27940273/gpr4-deficiency-alleviates-intestinal-inflammation-in-a-mouse-model-of-acute-experimental-colitis
#14
Edward J Sanderlin, Nancy R Leffler, Kvin Lertpiriyapong, Qi Cai, Heng Hong, Vasudevan Bakthavatchalu, James G Fox, Joani Zary Oswald, Calvin R Justus, Elizabeth A Krewson, Dorcas O'Rourke, Li V Yang
GPR4 is a proton-sensing G protein-coupled receptor that can be activated by extracellular acidosis. It has recently been demonstrated that activation of GPR4 by acidosis increases the expression of numerous inflammatory and stress response genes in vascular endothelial cells (ECs) and also augments EC-leukocyte adhesion. Inhibition of GPR4 by siRNA or small molecule inhibitors reduces endothelial cell inflammation. As acidotic tissue microenvironments exist in many types of inflammatory disorders, including inflammatory bowel disease (IBD), we examined the role of GPR4 in intestinal inflammation using a dextran sulfate sodium (DSS)-induced acute colitis mouse model...
February 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27938529/adhesions-small-bowel-obstruction-in-emergency-setting-conservative-or-operative-treatment
#15
M Assenza, I De Gruttola, D Rossi, S Castaldi, F Falaschi, G Giuliano
Adhesions small bowel obstructions (aSBO) are among the leading causes of emergency operative intervention. About the 80% of aSBO cases resolve without a surgical treatment. It's important to identify which patients could undergo a conservative treatment to prevent an useless surgery The aim of this study is to determine findings that can indicate whether patients with aSBO should undergo a conservative or a surgical treatment. 313 patients with diagnosis of submission of aSBO were restudied. Patients were divided into two groups based on the different type of treatment received, 225 patients who underwent surgical treatment within 24 hours after admission, 88 patients which underwent conservative treatment successfully...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27928685/laparoscopic-deloyers-procedure-for-tension-free-anastomosis-after-extended-left-colectomy-technique-and-results
#16
A Sciuto, C Grifasi, F Pirozzi, P Leon, R E M Pirozzi, F Corcione
BACKGROUND: The Deloyers procedure, which includes inversion of the right colon around the axis of the ileocolic vessels, can be used to achieve a well vascularized, tension-free colorectal anastomosis after extended left colectomy. The aim of this study is to report our technique and outcome in a series of ten consecutive patients who underwent right colonic transposition by laparoscopic approach. METHODS: Charts were retrospectively reviewed to analyze postoperative outcome and bowel function...
December 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27927245/congenital-adhesion-band-causing-small-bowel-obstruction-what-s-the-difference-in-various-age-groups-pediatric-and-adult-patients
#17
Kwang-Ho Yang, Tae-Beom Lee, Si-Hak Lee, Soo-Hong Kim, Yong-Hoon Cho, Hae-Young Kim
BACKGROUND: A congenital adhesion band is a rare condition, but may induce a small bowel obstruction (SBO) at any age. However, only a few sporadic case reports exit. We aimed to identify the clinical characteristics of congenital adhesion band manifesting a SBO stratified by age group between pediatric and adult patients. METHODS: The medical records of all patients with a SBO between Jan 1, 2009 and Dec 31, 2015 were retrospectively reviewed. Cases associated with previous surgical procedure and cases of secondary obstruction due to inflammatory processes or tumor and other systemic diseases were excluded...
December 7, 2016: BMC Surgery
https://www.readbyqxmd.com/read/27919731/nerve-sparing-laparoscopic-colposacropexy-using-a-percutaneous-surgical-system-a-case-report
#18
Federico Romano, Francesco Legge, Giovanni Scambia, Maurizio Guido
STUDY OBJECTIVE: To evaluate the feasibility, efficacy and safeness of nerve-sparing laparoscopic colposacropexy performed with a minimally invasive approach by using 2,9 mm Percuvance(TM) Percutaneous Surgical System (PSS) (The Percuvance(TM) System, Teleflex Inc., USA). DESIGN: Step-by-step video demonstration of the surgical technique. The Internal Department Committee approved this study. The patient was adequately informed about the possible risks and benefits of this experimental technique and a written consent agreeing to undergo the described procedure was signed...
December 2, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27916022/a-wandering-tube
#19
Ina Dubin, Moshe Gelber, Ami Schattner
The predominant causes of acute mechanical small bowel obstruction in geriatric patients are adhesions and hernias, which is not much different than in other adult age groups. Unusual etiologies may be encountered, such as volvulus or gallstone ileus, but a displaced feeding gastrostomy tube is a distinctly rare cause of intestinal obstruction which needs to be considered by emergency physicians as it may be increasingly encountered.
December 5, 2016: CJEM
https://www.readbyqxmd.com/read/27906758/30-day-readmission-after-operative-management-of-adhesive-small-bowel-obstruction
#20
Sean Nurmsoo, Mohammad Hajizadeh
No abstract text is available yet for this article.
November 30, 2016: Annals of Surgery
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