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vascular anaesthes ia

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https://www.readbyqxmd.com/read/2059916/effects-of-endothelin-3-on-diastolic-blood-pressure-of-pithed-sprague-dawley-wistar-kyoto-and-spontaneously-hypertensive-rats-before-and-after-pretreatment-with-nifedipine
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COMPARATIVE STUDY
R Tabrizchi, C R Triggle
Pressor actions of endothelin 3 (ET3) were examined in pithed Sprague-Dawley (SD), Wistar-Kyoto (WKY), and spontaneously hypertensive (SH) rats before and after the administration of the calcium channel antagonist, nifedipine. Systolic and diastolic blood pressures were recorded via an intra-arterial catheter from sodium pentobarbital anaesthized rats prior to pithing. The systolic and diastolic blood pressures recorded from SH rats were significantly greater than those of SD and WKY rats; however, after pithing there were no significant differences between the diastolic blood pressures among the various strains...
April 1991: Canadian Journal of Physiology and Pharmacology
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