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intraoperative analgesia and post operative pain

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https://www.readbyqxmd.com/read/27833559/the-opioid-sparing-effect-of-perioperative-dexmedetomidine-plus-sufentanil-infusion-during-neurosurgery-a-retrospective-study
#1
Shiyu Su, Chunguang Ren, Hongquan Zhang, Zhong Liu, Zongwang Zhang
Background: Approximately 60% of patients experience moderate-to-severe pain after neurosurgery, which primarily occurs in the first 24-72 h. Despite this, improved postoperative analgesia solutions after neurosurgery have not yet been devised. This retrospective study was conducted to evaluate the effect of intra- and post-operative infusions of dexmedetomidine (DEX) plus sufentanil on the quality of postoperative analgesia in patients undergoing neurosurgery. Methods: One hundred and sixty-three post-neurosurgery patients were divided into two groups: Group D (DEX infusion at 0...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27790557/oral-clonidine-vs-oral-pregabalin-premedication-to-attenuate-pressor-response-to-direct-laryngoscopy-in-patients-undergoing-laparoscopic-cholecystectomy-a-randomized-double-blind-study
#2
Shirin Parveen, Devendra Singh Negi, Rajesh Kumar, Mohd Chand Bagwan
INTRODUCTION: Direct laryngoscopy and tracheal intubation has adverse effects like tachycardia, hypertension, myocardial ischemia and cerebral haemorrhage. There are several studies on various pharmacological agents to attenuate this response. AIM: This study was designed to compare efficacy and safety of oral clonidine and oral pregabalin premedication to attenuate stress response in patients undergoing laparoscopic cholecystectomy. MATERIALS AND METHODS: Total 80 patients of ASA grade I and II, aged between 20-60 years of both sexes scheduled for elective laparoscopic cholecystectomy were included in the study...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27761415/preemptive-oral-clonidine-provides-better-sedation-than-intravenous-midazolam-in-brachial-plexus-nerve-blocks
#3
Faramarz Mosaffa, Seyed Amir Mohajerani, Reza Aminnejad, Ali Solhpour, Shideh Dabir, Gholam Reza Mohseni
BACKGROUND: Preemptive analgesia is the blocking of pain perception afferent pathways before noxious painful stimuli. Clonidine is an alpha agonist drug that is partially selective for α-2 adrenoreceptors. Clonidine is used as anti-anxiety medication and an, analgesic, and it prolongs the duration of the block in the brachial plexus block. OBJECTIVES: To compare the effect of preemptive clonidine with midazolam on intraoperative sedation, duration of block, and postoperative pain scores...
June 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27746568/comparisons-of-single-injection-thoracic-paravertebral-block-with-ropivacaine-and-bupivacaine-in-breast-cancer-surgery-a-prospective-randomized-double-blinded-study
#4
Ashutosh Sahu, Rajnish Kumar, Mumtaz Hussain, Ajit Gupta, K H Raghwendra
BACKGROUND: Regional anesthesia using paravertebral block has been suggested as an ideal adjunct to general anesthesia for modified radical mastectomy. Paravertebral block is an effective management of peri-operative pain for Modified radical mastectomy, however, there are no established guidelines regarding what is the most suitable strategy when varying drugs and dosages between different groups. AIM: To evaluate the effectiveness of paravertebral block comparing the most frequently employed drugs in this procedure (bupivacaine vs ropivacaine)...
September 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/27293824/management-of-post-operative-pain-by-placement-of-an-intraoperative-intercostal-catheter-after-single-port-video-assisted-thoracoscopic-surgery-a-propensity-score-matched-study
#5
Ching-Feng Wu, Ming-Ju Hsieh, Hung-Pin Liu, Diego Gonzalez-Rivas, Yun-Hen Liu, Yi-Cheng Wu, Yin-Kai Chao, Ching-Yang Wu
BACKGROUND: The establishment of a golden standard for post-operative analgesia after thoracic surgery remains an unresolved issue. Benefiting from the rapid development of single port video-assisted thoracoscopic surgery (VATS), a good candidate for the alleviation of patients' pain is the placement of an intercostal catheter (ICC) safely after uniport VATS. We hypothesized that continual infusion through ICC could provide effective analgesia for patients with only one wound and we evaluate its postoperative analgesic function in uniport VATS patients with or without intercostal nerve blockade...
June 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27175680/effect-of-dexmedetomidine-alone-for-intravenous-patient-controlled-analgesia-after-gynecological-laparoscopic-surgery-a-consort-prospective-randomized-controlled-trial
#6
Xiuqin Wang, Wenjuan Liu, Zan Xu, Fumei Wang, Chuanfeng Zhang, Baosheng Wang, Kaiguo Wang, Jingui Yu
Gynecological laparoscopic surgery is minimally invasive compared with open surgical approaches, but postoperative pain is generally undermanaged. Pain management strategies related to the procedure-specific efficacy are needed. Many studies have shown that dexmedetomidine (DEX) has opioid-sparing properties. It is not clear whether DEX used alone for intravenous patient-controlled analgesia (PCA) could reduce postoperative pain after an invasive procedure. We hypothesized that DEX alone would reduce postoperative pain in women patients undergoing an elective gynecological laparoscopic procedure...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27117906/clinical-outcomes-during-the-learning-curve-of-midline-lumbar-fusion-midlf%C3%A2-using-the-cortical-bone-trajectory
#7
Bassam Dabbous, Daniel Brown, Abraham Tsitlakidis, Vasileios Arzoglou
OBJECTIVE: The objective of this study is to review the clinical outcomes of a novel minimally invasive surgery (MIS) technique for the treatment of instability of the lumbar spine using the cortical bone trajectory (CBT). We present a prospective review of the clinical outcomes from the first 25 consecutive cases in a single unit during the initial learning phase. MATERIALS AND METHODS: The investigation group included the first 25 patients (eight males and 17 females) who underwent MIDLF® since the introduction of this technique in a single unit...
July 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27113396/the-role-of-liposomal-bupivacaine-in-reduction-of-postoperative-pain-after-transforaminal-lumbar-interbody-fusion-a-clinical-study
#8
Jackson Kim, Shane M Burke, James T Kryzanski, Russel J Roberts, Marie Roguski, Evan Qu, Steven W Hwang, Penny P Liu, Adriana Desilier, Ron I Riesenburger
BACKGROUND: Postoperative pain after transforaminal lumbar interbody fusion (TLIF) is a barrier to early mobility. Intraoperative local infiltration of anesthetic agents is standard practice to alleviate postoperative pain. Liposomal formulations may prolong the action of these anesthetic agents. The purpose of this study was to investigate the role of liposomal bupivacaine in postoperative pain control in patients undergoing unilateral, single-level TLIF. METHODS: From a cohort of 74 patients, half received nonliposomal local anesthetic and half received liposomal bupivacaine (LB) (LB group) via local infiltration...
July 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27008577/peri-incisional-and-intraperitoneal-ropivacaine-administration-a-new-effective-tool-in-pain-control-after-laparoscopic-surgery-in-gynecology-a-randomized-controlled-clinical-trial
#9
Carlo Saccardi, Salvatore Gizzo, Amerigo Vitagliano, Marco Noventa, Massimo Micaglio, Matteo Parotto, Mauro Fiorese, Pietro Litta
BACKGROUND: A proportion of patients undergoing laparoscopic gynecological surgery experiences excessive post-operative pain, which results in high rescue analgesic treatment and prolonged hospitalization. The aim of our study was to evaluate the efficacy of intraoperative topical ropivacaine in the control of post-operative pain in the first 48 h after operative laparoscopy for benign adnexal or uterine pathologies . METHODS: We conducted a prospective, randomized, double-blind, placebo-controlled clinical trial...
December 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26968272/effects-of-bupivacaine-infiltration-on-postoperative-tramadol-consumption-in-elective-day-care-unilateral-inguinal-hernia-repair
#10
Rehan Muhammad Qureshi, Fauzia Anis Khan
OBJECTIVE: To determine the difference in analgesic requirement in terms of mean postoperative narcotic consumption and mean postoperative pain score in patients undergoing unilateral inguinal hernia repair with or without bupivacaine infiltration as day-care patients. METHODS: The randomised controlled trial was conducted at Aga Khan University Hospital, Karachi, from June to December 2011, and comprised patients who were randomly divided into groups A and B. Tramadol 1...
March 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26894127/a-comparison-between-non-descent-vaginal-hysterectomy-and-total-abdominal-hysterectomy
#11
Dhivya Balakrishnan, Gharphalia Dibyajyoti
INTRODUCTION: Hysterectomy is one of the most common gyneacological surgeries performed worldwide. The vaginal technique has been introduced and performed centuries back, but has been less successful due to lack of experience and enthusiasm among Gynaecologists, due to a misconception that the abdominal route is safer and easier. AIM: To evaluate the most efficient route of hysterectomy in women with mobile nonprolapsed uteri of 12 weeks or lesser by comparing the intra and postoperative complications of vaginal and abdominal hysterectomies...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26859916/regional-analgesia-for-post-operative-pain-management-initial-experience-in-a-low-resource-setting
#12
A A Yunus, E O Nwasor, M E Idris, F S Ejagwulu
OBJECTIVE: The aim of this study is to demonstrate the use of some regional anaesthetic techniques in effective postoperative pain control in a low resource setting. We also wanted to find out the potential benefits and prospects of regional techniques to achieve effective postoperative analgesia. DESIGN: This study was a prospective observational study in which 25 patients presenting for various orthopaedic and general surgical procedures were recruited randomly...
March 2012: East African Medical Journal
https://www.readbyqxmd.com/read/26854288/extra-abdominal-removal-of-placenta-during-cesarean-section-a-prospective-randomized-controlled-trial-of-a-novel-technique
#13
Baris Kaya, Onur Guralp, Korkut Daglar, Abdullah Tuten, Aygul Demirol, Eyup Yayci, Tijen Atacag, Askin Dogan
AIM: To evaluate intraoperative and early postoperative outcomes of a novel placenta delivery technique; extra-abdominal removal vs. intra-abdominal removal of the placenta during cesarean section (CS). METHODS: A total of 210 women delivering by CS at term in a tertiary university hospital between March 2014 and January 2015 were randomized to extra-abdominal removal vs. intra-abdominal removal of the placenta. The women were randomly allocated to the extra- (group 1) or intra-abdominal removal group (group 2) according to random sampling method, where women with even and odd numbers were allocated to intra- and extra-abdominal groups, respectively...
July 1, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/26742414/-metoclopramide-induced-acute-dystonia-during-intravenous-patient-controlled-analgesia-with-droperidol
#14
Kotoe Kamata, Emi Takahashi, Nobutada Morioka, Keiko Nakashima, Motoyo Iwade, Makoto Ozaki
A patient developed acute dystonia following intravenous administration of metocroplamide 20 mg. A 34-year-old woman underwent right hepatectomy, under general anesthesia managed with desflurane, remifentanil, and rocuronium. At the start of surgery, droperidol 1.5 mg was given intravenously for anti-emetic prophylaxis. Operation was completed uneventfully. Intravenous patient-controlled analgesia (i.v.-PCA) with fentanyl, containing droperidol, was selected for postoperative pain management The patient showed a reasonable postoperative course; however, around 15 hours post-operatively, she complained of nausea, although droperidol 2...
October 2015: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/26588217/ultrasound-assisted-thoracic-paravertebral-block-reduces-intraoperative-opioid-requirement-and-improves-analgesia-after-breast-cancer-surgery-a-randomized-controlled-single-center-trial
#15
RANDOMIZED CONTROLLED TRIAL
Lijian Pei, Yidong Zhou, Gang Tan, Feng Mao, Dongsheng Yang, Jinghong Guan, Yan Lin, Xuejing Wang, Yanna Zhang, Xiaohui Zhang, Songjie Shen, Zhonghuang Xu, Qiang Sun, Yuguang Huang
OBJECTIVES: The contribution of ultrasound-assisted thoracic paravertebral block to postoperative analgesia remains unclear. We compared the effect of a combination of ultrasound assisted-thoracic paravertebral block and propofol general anesthesia with opioid and sevoflurane general anesthesia on volatile anesthetic, propofol and opioid consumption, and postoperative pain in patients having breast cancer surgery. METHODS: Patients undergoing breast cancer surgery were randomly assigned to ultrasound-assisted paravertebral block with propofol general anesthesia (PPA group, n = 121) or fentanyl with sevoflurane general anesthesia (GA group, n = 126)...
2015: PloS One
https://www.readbyqxmd.com/read/26468074/comparison-of-fentanyl-versus-meperidine-as-supplements-to-epidural-clonidine-bupivacaine-in-patients-with-lower-limb-orthopedic-surgery-under-combined-spinal-epidural-anesthesia
#16
RANDOMIZED CONTROLLED TRIAL
Ayman Abd Al-Maksoud Yousef, Ashraf Mohamed Atef, Waleed Mohamed Awais
BACKGROUND: The analgesic and sedative effect of clonidine explain its common use as adjuvant in regional anesthesia, however the hemodynamic instability associated with its neuroaxial administration is the major drawback. Our study hypothesis is to compare the hemodynamic and analgesic effect of epidural fentanyl in comparison to meperidine when added to clonidine in patients undergoing lower limbs orthopedic surgery using combined spinal-epidural anesthesia. METHODS: One hundred thirty five ASA physical status I or II patients were recruited for lower limb orthopedic surgery...
October 14, 2015: BMC Anesthesiology
https://www.readbyqxmd.com/read/26350110/effects-of-transcutaneous-electrical-acupoint-stimulation-at-different-frequencies-on-perioperative-anesthetic-dosage-recovery-complications-and-prognosis-in-video-assisted-thoracic-surgical-lobectomy-a-randomized-double-blinded-placebo-controlled-trial
#17
Shun Huang, WenPing Peng, Xue Tian, Hansheng Liang, Zhe Jia, Theresa Lo, Miao He, Yi Feng
BACKGROUND: Transcutaneous electrical acupoint stimulation (TEAS), a non-invasive and non-pharmacological adjunctive intervention for perioperative analgesia, may also reduce the incidence of postoperative pulmonary complications. The effect of TEAS on video-assisted thoracic surgical (VATS) patients is still unknown, however. The purpose of this study was to investigate the effects of TEAS of different frequency on perioperative anesthetic dosage, recovery, complications, and prognosis for patients undergoing VATS lobectomy...
September 8, 2015: Journal of Anesthesia
https://www.readbyqxmd.com/read/26324029/anesthetic-management-in-children-with-congenital-lobar-emphysema
#18
M Celik, A Dostbil, M Aksoy, H A Alici, N Dogan, I Ince, Y Aydin, A Ahiskalioglu
BACKGROUND: The cause of congenital lobar emphysema (CLE) is unknown and characterized by hyperinflation of one or more lobes of the lung. The purpose of this retrospective study was to present the anesthetic management of children with congenital lobar emphysema (CLE) receiving treatment in our center. METHODS: Ten children underwent CLE-related surgical treatment in our center between March 1995 and August 2014. All cases were diagnosed on the basis of postero-anterior chest radiography and computerized tomography...
July 2015: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/26188896/post-operative-pain-control-for-burn-reconstructive-surgery-in-a-resource-restricted-country-with-subcutaneous-infusion-of-local-anesthetics-through-a-soaker-catheter-to-the-surgical-site-preliminary-results
#19
RANDOMIZED CONTROLLED TRIAL
Gennadiy Fuzaylov, Tara L Kelly, Cheryl Bline, Alexander Dunaev, Maggie L Dylewski, Daniel N Driscoll
OBJECTIVE: Post-operative pain can significantly affect a patient's ability to recover following surgery. In this study we introduced the concept of post-operative pain evaluation of burn patients as well as a technique for placement and use of subcutaneous catheters for continuous infusion of local anesthetic to provide analgesia following skin harvest from the lateral thigh in a hospital in resource-restricted country--Ukraine. METHODS: A total of 109 patients were enrolled in this study...
December 2015: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/26182775/comparison-of-efficacy-of-spinal-anaesthesia-and-sub-fascial-local-anaesthetic-inguinal-field-block-for-open-inguinal-hernia-repair-a-single-institutional-experience
#20
RANDOMIZED CONTROLLED TRIAL
Natasha Shafique, Haroon Ur Rashid, Muhammad Ijaz Raja, Mohammad Saeed
BACKGROUND: The use of local anaesthetic for open inguinal hernia surgery has long been restricted to specialist centres. This study aimed to compare the efficacy of spinal anaesthesia and sub-fascial local anaesthetic (LA) for performing open hernia repair and at the same time provide better post op pain relief and early mobilization. Methods: In this randomized clinical trial, 62 male patients aged 16-72 were randomly allocated to two groups. Group A received mixture of 20 ml 0.5% bupivacain,20ml 2% lignocaine with adrenaline, 20m normal saline (N/S), 3 ml NaHCO3 sub-fascially for Local-anaesthetic (LA) inguinal field...
January 2015: Journal of Ayub Medical College, Abbottabad: JAMC
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