keyword
MENU ▼
Read by QxMD icon Read
search

Bifidobacterium

keyword
https://www.readbyqxmd.com/read/29455070/oral-engineered-bifidobacterium-longum-expressing-rhmnsod-to-suppress-experimental-colitis
#1
Mengge Liu, Shiyu Li, Qian Zhang, Zhenrui Xu, Jiajia Wang, Hanxiao Sun
In recent years, using genetic engineering and bioengineering techniques, Bifidobacterium as a carrier to express specific functions of the protein or polypeptide, has become a new treatment for disease. Ulcerative colitis (UC) is a type of inflammatory bowel diseases (IBD). Although the cause of this inflammatory disorder is still unknown, a large amount of evidence suggests that ulcerative colitis is associated with increased activity of reactive oxygen species (ROS), manganese superoxide dismutase (MnSOD) is a kind of superoxide dismutase (SOD) has been demonstrated to play a key role in the pathophysiology of colitis...
February 14, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29453804/probiotics-affect-one-carbon-metabolites-and-catecholamines-in-a-genetic-rat-model-of-depression
#2
Sandra Tillmann, Hussain M Awwad, Amanda R Eskelund, Giulia Treccani, Juergen Geisel, Gregers Wegener, Rima Obeid
SCOPE: Probiotics may influence one-carbon (C1) metabolism, neurotransmitters, liver function markers, or behavior. METHODS AND RESULTS: Male adult Flinders Sensitive Line rats (model of depression, FSL; n = 22) received Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 (10 9 or 10 10 colony-forming units/d) or vehicle for 10 weeks. The controls, Flinders Resistant Line rats (FRL, n = 8), only received vehicle. C1-related metabolites were measured in plasma, urine, and different tissues...
February 17, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29451876/comparative-genomic-analysis-of-the-multispecies-probiotic-marketed-product-vsl-3
#3
François P Douillard, Diego Mora, Robyn T Eijlander, Michiel Wels, Willem M de Vos
Several probiotic-marketed formulations available for the consumers contain live lactic acid bacteria and/or bifidobacteria. The multispecies product commercialized as VSL#3 has been used for treating various gastro-intestinal disorders. However, like many other products, the bacterial strains present in VSL#3 have only been characterized to a limited extent and their efficacy as well as their predicted mode of action remain unclear, preventing further applications or comparative studies. In this work, the genomes of all eight bacterial strains present in VSL#3 were sequenced and characterized, to advance insights into the possible mode of action of this product and also to serve as a basis for future work and trials...
2018: PloS One
https://www.readbyqxmd.com/read/29451186/-lactobacillus-acidophilus-and-bifidobacterium-longum-supernatants-upregulate-the-serotonin-transporter-expression-in-intestinal-epithelial-cells
#4
Ya-Nan Cao, Li-Juan Feng, Bang-Mao Wang, Kui Jiang, Shu Li, Xin Xu, Wei-Qiang Wang, Jing-Wen Zhao, Yu-Ming Wang
Background/Aims: Probiotics play a role in relieving irritable bowel syndrome (IBS); however, the underlying mechanism is yet unclear. The aim of the study was to investigate the effects of the supernatants of Lactobacillus acidophilus and Bifidobacterium longum on the expression of serotonin transporter (SERT) messenger ribonucleic acid (mRNA) and protein. Materials and Methods: HT-29 and Caco-2 cells were treated with different concentrations of L. acidophilus and B...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29450747/efficacy-of-bifidobacterium-breve-fermented-milk-in-maintaining-remission-of-ulcerative-colitis
#5
Katsuyoshi Matsuoka, Yukari Uemura, Takanori Kanai, Reiko Kunisaki, Yasuo Suzuki, Kaoru Yokoyama, Naoki Yoshimura, Toshifumi Hibi
BACKGROUND: Fermented milk products containing Bifidobacterium breve strain Yakult (BFM) may improve clinical status in ulcerative colitis (UC) patients. AIMS: To assess efficacy of BFM in maintaining remission in Japanese patients with quiescent UC. METHODS: This double-blind study (B-FLORA) enrolled 195 patients with quiescent UC, randomized to receive one pack of BFM fermented milk per day [Bifidobacterium breve strain Yakult (10 billion bacteria) and Lactobacillus acidophilus (1 billion bacteria)] (n = 98) or matching placebo (n = 97) for 48 weeks...
February 15, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29448943/cloning-and-expression-of-the-sucrose-phosphorylase-gene-in-bacillus-subtilis-and-synthesis-of-kojibiose-using-the-recombinant-enzyme
#6
Miaomiao Wang, Jing Wu, Dan Wu
BACKGROUND: Kojibiose as a prebiotic and inhibitor of α-glucosidase exhibits potential for a wide range of applications in the food and medicine fields; however, large-scale separation and extraction of kojibiose from nature is difficult. Sucrose phosphorylase (SPase) can be used for the production of kojibiose, and currently, SPase is only heterologously expressed in E. coli, making it unsuitable for use in the food industry. However, Bacillus subtilis is generally considered to be a safe organism potentially useful for SPase expression...
February 15, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29445853/xylo-and-arabinoxylooligosaccharides-from-wheat-bran-by-endoxylanases-utilisation-by-probiotic-bacteria-and-structural-studies-of-the-enzymes
#7
Sindhu Mathew, Anna Aronsson, Eva Nordberg Karlsson, Patrick Adlercreutz
Xylooligosaccharides (XOS) and arabinoxylooligosaccharides (AXOS) were produced from the insoluble arabinoxylan fraction of pretreated wheat bran by endoxylanases. The glycoside hydrolase (GH) family 10 xylanases GsXyn10A from Geobacillus stearothermophilus and RmXyn10A-CM from Rhodothermus marinus produced the AXOS A 3 X, A 2 XX and A 2 + 3 XX in addition to XOS. RmXyn10A-CM also produced XA 2 + 3 XX due to its non-conserved aglycone region accommodating additional arabinose substitutions in subsite +2. The GH11 enzymes, Pentopan from Thermomyces lanuginosus and NpXyn11A from Neocallimastix patriciarum had minor structural differences affecting hydrogen bonds in subsites -3 and +3, with similar hydrolysis profiles producing XA 3 XX as major AXOS and minor amounts of XA 2 XX but different ratios of X 3 /X 2 ...
February 14, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29439741/antibiotic-mediated-changes-in-the-fecal-microbiome-of-broiler-chickens-define-the-incidence-of-antibiotic-resistance-genes
#8
Wenguang Xiong, Yulin Wang, Yongxue Sun, Liping Ma, Qinglin Zeng, Xiaotao Jiang, Andong Li, Zhenling Zeng, Tong Zhang
BACKGROUND: Antimicrobial agents have been widely used in animal farms to prevent and treat animal diseases and to promote growth. Antimicrobial agents may change the bacterial community and enhance the resistome in animal feces. We used metagenome-wide analysis to investigate the changes in bacterial community, variations in antibiotic resistance genes (ARGs), and their bacterial hosts in the feces of broiler chickens over a full-treatment course of chlortetracycline at low and therapeutic dose levels...
February 13, 2018: Microbiome
https://www.readbyqxmd.com/read/29439731/metalonda-a-flexible-r-package-for-identifying-time-intervals-of-differentially-abundant-features-in-metagenomic-longitudinal-studies
#9
Ahmed A Metwally, Jie Yang, Christian Ascoli, Yang Dai, Patricia W Finn, David L Perkins
BACKGROUND: Microbial longitudinal studies are powerful experimental designs utilized to classify diseases, determine prognosis, and analyze microbial systems dynamics. In longitudinal studies, only identifying differential features between two phenotypes does not provide sufficient information to determine whether a change in the relative abundance is short-term or continuous. Furthermore, sample collection in longitudinal studies suffers from all forms of variability such as a different number of subjects per phenotypic group, a different number of samples per subject, and samples not collected at consistent time points...
February 13, 2018: Microbiome
https://www.readbyqxmd.com/read/29434698/effect-of-clostridium-butyricum-supplementation-on-the-development-of-intestinal-flora-and-the-immune-system-of-neonatal-mice
#10
Rui-Xue Miao, Xin-Xin Zhu, Chao-Min Wan, Zhi-Ling Wang, Yang Wen, Yi-Yuan Li
The objective of the present study was to examine whether Clostridium butyricum supplementation has a role in the regulation of the intestinal flora and the development of the immune system of neonatal mice. A total of 30 pregnant BALB/c mice, including their offspring, were randomly divided into three groups: In the maternal intervention group (Ba), maternal mice were treated with Clostridium butyricum from birth until weaning at postnatal day 21 (PD21) followed by administration of saline to the offspring at PD21-28; in the offspring intervention group (Ab), breast-feeding maternal mice were supplemented with saline and offspring were directly supplemented with Clostridium butyricum from PD21-28; in the both maternal and offspring intervention group (Bb), both maternal mice and offspring were supplemented with Clostridium butyricum at PD 0-21 and at PD21-28...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29432368/fecal-microbiota-differences-according-to-the-risk-of-advanced-colorectal-neoplasms
#11
Hyo-Joon Yang, Min-Jung Kwon, Yoosoo Chang, Seul-Ki Song, Kwang-Sung Ahn, Han-Na Kim, Yeojun Yun, Hyung-Lae Kim, Dong Il Park
GOALS AND BACKGROUND: This study aimed to compare differences in the fecal microbiota according to the risk of advanced colorectal neoplasia (ACN) based on a risk-score model in a large Korean cohort. STUDY: Stool samples were collected from 1122 health screening recipients: 404 enrolled in the average risk (AR) group, 514 in the moderate risk (MR) group, and 204 in the high risk (HR) group, in accordance with their risk of ACN. The fecal microbiota was characterized using pyrosequencing of the V3-V4 region of the 16S rRNA genes...
February 9, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29432061/atorvastatin-treatment-modulates-the-gut-microbiota-of-the-hypercholesterolemic-patients
#12
Tariq Jamal Khan, Youssri M Ahmed, Mazin A Zamzami, Aisha M Siddiqui, Imran Khan, Othman A S Baothman, Mohamed G Mehanna, Abudukadeer Kuerban, Mohammed Kaleemuddin, Muhammad Yasir
Hypercholesterolemia is one of the most important risk factors for development of cardiovascular diseases. The composition of gut microbiota (total microbes residing in the gut) impacts on cholesterol and lipid metabolism. On the contrary, alterations in gut microbiota in response to hypercholesterolemia or drug treatment with atorvastatin (a cholesterol-lowering agent) are rarely investigated. We performed 16S rDNA amplicon sequencing to evaluate the gut bacterial community of 15 untreated hypercholesterolemic patients (HP) and 27 atorvastatin-treated hypercholesterolemic patients (At-HP) and compared with 19 healthy subjects (HS)...
February 2018: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29427960/performance-and-genome-centric-metagenomics-of-thermophilic-single-and-two-stage-anaerobic-digesters-treating-cheese-wastes
#13
Alessandra Fontana, Stefano Campanaro, Laura Treu, Panagiotis G Kougias, Fabrizio Cappa, Lorenzo Morelli, Irini Angelidaki
The present research is the first comprehensive study regarding the thermophilic anaerobic degradation of cheese wastewater, which combines the evaluation of different reactor configurations (i.e. single and two-stage continuous stirred tank reactors) on the process efficiency and the in-depth characterization of the microbial community structure using genome-centric metagenomics. Both reactor configurations showed acidification problems under the tested organic loading rates (OLRs) of 3.6 and 2.4 g COD/L-reactor day and the hydraulic retention time (HRT) of 15 days...
February 7, 2018: Water Research
https://www.readbyqxmd.com/read/29426421/structural-properties-and-prebiotic-activities-of-fractionated-lotus-seed-resistant-starches
#14
Hongliang Zeng, Peilin Chen, Chuanjie Chen, Cancan Huang, Shan Lin, Baodong Zheng, Yi Zhang
The objective of this study was to fractionate lotus seed resistant starch (LRS3) and investigate their structural properties and prebiotic activities. Two main fractions of resistant starch precipitated gradually by ethanol at concentrations of 20% and 30% were named as LRS3-20% and LRS3-30%, respectively. The swelling power and solubility of LRS3-20% were smaller compared to LRS3-30%, and their moisture and resistant starch contents were not significantly different. LRS3-20% and LRS3-30% had molecular weights mainly of 2...
June 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29423216/dietary-proline-supplementation-alters-colonic-luminal-microbiota-and-bacterial-metabolite-composition-between-days-45-and-70-of-pregnancy-in-huanjiang-mini-pigs
#15
Yujiao Ji, Qiuping Guo, Yulong Yin, Francois Blachier, Xiangfeng Kong
Background: Pregnancy is associated with important changes in gut microbiota composition. Dietary factors may affect the diversity, composition, and metabolic activity of the intestinal microbiota. Among amino acids, proline is known to play important roles in protein metabolism and structure, cell differentiation, conceptus growth and development, and gut microbiota re-equilibration in case of dysbiosis. Results: Dietary supplementation with 1% proline decreased (P < 0...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29422338/linear-%C3%AE-1%C3%A2-%C3%A2-%C3%A2-6-d-glucan-from-bifidobacterium-bifidum-bim-%C3%B0-733d-is-low-molecular-mass-biopolymer-with-unique-immunochemical-properties
#16
Elena P Kiseleva, Konstantin I Mikhailopulo, Evelina L Zdorovenko, Yuriy A Knirel, Galina I Novik
Role of microorganisms in induction of/protection from autoimmune diseases is proven though molecular mechanisms and bacterial/viral/yeast biopolymers responsible for these effects are in the research stage. Autoantobodies (AAbs) to thyroid peroxidase (anti-TPO) and thyroglobulin (anti-Tg) as well as AAbs to transglutaminase 2 (anti-TG2) and antibodies to gliadins (anti-gliadins) are serological markers of autoimmune thyroid disease and celiac disease, respectively, and players in pathogenesis of these autoimmune diseases...
December 20, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/29421652/functional-and-structural-characterization-of-a-%C3%AE-glucosidase-involved-in-saponin-metabolism-from-intestinal-bacteria
#17
Shan Yan, Peng-Cheng Wei, Qiao Chen, Xin Chen, Shi-Cheng Wang, Jia-Ru Li, Chuan Gao
Saponins are natural glycosides widely used in medicine and the food industry. Although saponin metabolism in human is dependent on intestinal microbes, few involving bacteria enzymes have been identified. We cloned BlBG3, a GH3 β-glucosidase from Bifidobacterium longum, from human stool. We found that BlBG3 catalyzes the hydrolysis of glycoside furostanol and ginsenoside Rb1 at higher efficiency than other microbial β-glucosidases. Structural analysis of BlBG3 in complex with d-glucose revealed its three unique loops, which form a deep pocket and participate in substrate binding...
February 5, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29416529/prebiotic-wheat-bran-fractions-induce-specific-microbiota-changes
#18
Kevin D'hoe, Lorenza Conterno, Francesca Fava, Gwen Falony, Sara Vieira-Silva, Joan Vermeiren, Kieran Tuohy, Jeroen Raes
Wheat bran fibers are considered beneficial to human health through their impact on gut microbiota composition and activity. Here, we assessed the prebiotic potential of selected bran fractions by performing a series of fecal slurry anaerobic fermentation experiments using aleurone as well as total, ultrafine, and soluble wheat bran (swb) as carbon sources. By combining amplicon-based community profiling with a fluorescent in situ hybridization (FISH) approach, we found that incubation conditions favor the growth of Proteobacteria such as Escherichia and Bilophila...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29413672/impact-of-whey-protein-coating-incorporated-with-bifidobacterium-and-lactobacillus-on-sliced-ham-properties
#19
Joana Odila Pereira, José Soares, Maria J P Monteiro, Ana Gomes, Manuela Pintado
Edible coatings/films with functional ingredients may be a solution to consumers' demands for high-quality food products and an extended shelf-life. The aim of this work was to evaluate the antimicrobial efficiency of edible coatings incorporated with probiotics on sliced ham preservation. Coatings was developed based on whey protein isolates with incorporation of Bifidobacterium animalis Bb-12® or Lactobacillus casei-01. The physicochemical analyses showed that coating decreased water and weight loss on the ham...
January 31, 2018: Meat Science
https://www.readbyqxmd.com/read/29410448/intestinal-microbiota-development-and-gestational-age-in-preterm-neonates
#20
Katri Korpela, Elin W Blakstad, Sissel J Moltu, Kenneth Strømmen, Britt Nakstad, Arild E Rønnestad, Kristin Brække, Per O Iversen, Christian A Drevon, Willem de Vos
The intestinal microbiota is an important contributor to the health of preterm infants, and may be destabilized by a number of environmental factors and treatment modalities. How to promote the development of a healthy microbiota in preterm infants is largely unknown. We collected fecal samples from 45 breastfed preterm very low birth weight (birth weight < 1500 g) infants from birth until 60 days postnatal age to characterize the intestinal microbiota development during the first weeks of life in preterm infants...
February 6, 2018: Scientific Reports
keyword
keyword
117573
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"