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Bifidobacterium

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https://www.readbyqxmd.com/read/28324207/fructooligosaccharide-intake-promotes-epigenetic-changes-in-the-intestinal-mucosa-in-growing-and-ageing-rats
#1
Glaucia Carielo Lima, Vivian Cristine Correa Vieira, Cinthia Baú Betim Cazarin, Rafaela da Rosa Ribeiro, Stanislau Bogusz Junior, Cibele Lima de Albuquerque, Ramon Oliveira Vidal, Claudia Cardoso Netto, Áureo Tatsumi Yamada, Fabio Augusto, Mário Roberto Maróstica Junior
PURPOSE: The aim of this study was to investigate the relationship between fructooligosaccharide (FOS) intake at different life stages of Wistar rats and its stimulatory effects on intestinal parameters. METHODS: Recently weaned and ageing female rats were divided into growing and ageing treatments, which were fed diets that partially replaced sucrose with FOS for 12 weeks. RESULTS: Dietary FOS intake induced a significant increase in the numbers of Bifidobacterium and Lactobacillus in growing rats...
March 21, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28317073/effect-of-8-weeks-prebiotics-probiotics-supplementation-on-alcohol-metabolism-and-blood-biomarkers-of-healthy-adults-a-pilot-study
#2
Christopher Irwin, Saman Khalesi, Amanda J Cox, Gary Grant, Andrew K Davey, Andrew C Bulmer, Ben Desbrow
PURPOSE: Modulating gut bacteria via regular prebiotics/probiotics consumption may improve the metabolism of acute alcohol ingestion. This study investigated the impact of 8-weeks prebiotics/probiotics supplementation on microbiome changes and responses to acute alcohol consumption. METHODS: 38 participants (21 females, 23.6 ± 3.4 kg m(-2), mean ± SD) attended the laboratory on two occasions separated by an 8-week intervention period. On each of these visits, a dose of alcohol (0...
March 19, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28316949/evaluation-of-the-role-of-probiotics-in-endodontic-treatment-a-preliminary-study
#3
Aarti Bohora, Sharad Kokate
AIMS AND OBJECTIVES: The principal goal of endodontics is the prevention of periapical infection. Acute and chronic apical periodontitis occur due to the persistence of pathogenic microorganisms such as Enterococcus faecalis and Candida albicans harboring the root canal systems of the teeth. The concept of the use of probiotics in addressing endodontic disease is new and has not been studied adequately. On the basis of the success of probiotics in periodontal treatment, this preliminary work was performed (a) to evaluate the antibacterial efficacy of probiotics against common endodontic pathogens, i...
January 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28314858/identification-and-characterization-of-a-20%C3%AE-hydroxysteroid-dehydrogenase-from-the-anaerobic-gut-bacterium-butyricicoccus-desmolans-atcc-43058
#4
Saravanan Devendran, Celia Méndez-Garcia, Jason M Ridlon
Members of the gastrointestinal microbiota are known to convert glucocorticoids to androstanes, which can be subsequently converted to potent androgens by other members of the gut microbiota or host tissues. Butyricicoccus desmolans and Clostridium cadaveris has previously been reported for steroid-17,20-desmolase and 20β-hydroxysteroid dehydrogenase (20β-HSDH) activities that were responsible for androstane formation from cortisol, however the gene encoding these enzymes has yet to be reported. In this work, we identified and located a gene encoding 20β-HSDH in both B...
March 17, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28314100/attenuated-mtor-signaling-and-enhanced-glucose-homeostasis-by-dietary-supplementation-with-lotus-seedpod-oligomeric-procyanidins-in-streptozotocin-stz-induced-diabetic-mice
#5
Xiaopeng Li, Yong Sui, Qian Wu, Bijun Xie, Zhida Sun
This study investigated the protective role of lotus seedpod oligomeric procyanidins (LSOPC) and synbiotics (Bifidobacterium Bb-12 and xylo-oligosaccharide) against high fat and streptozotocin (STZ)-induced diabetes. Administration of LSOPC or synbiotics have no effect on blood glucose in normal mice. Treatments with LSOPC for 12 weeks markedly reduced blood glucose, FFA, endotoxin, GHbA1c and improved glucose homeostasis, lipid metabolism and insulin level. In addition, administration of LSOPC significantly reversed the increase of mTOR and p66Shc in liver, skeletal muscle and white adipose tissue (WAT)...
March 17, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28302207/-a-preliminary-analysis-of-changes-in-composition-of-intestinal-microbiota-during-infancy-using-polymerase-chain-reaction-denaturing-gradient-gel-electrophoresis
#6
Shan-Shan Li, Jun-Jie Miao, Zi-Xi Wu, Jian-Rong Yao, Ming Li, Qian Yu, Fang He
OBJECTIVE: To investigate the composition of bacteria in the stools of infants and the colonization of intestinal microbiota during infancy. METHODS: Fresh stools were collected from 15 healthy infants at 0, 2, 4, 7, 10, 14, and 28 days and 3, 6, and 12 months after birth. Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) was used to analyze the composition of intestinal microbiota, perform sequencing of dominant bacteria, and to analyze the changes in the composition of intestinal microbiota during infancy...
March 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28300786/hypocholesterolemic-effects-of-probiotic-mixture-on-diet-induced-hypercholesterolemic-rats
#7
Shang-Jin Kim, Sang Hoon Park, Hong-Sig Sin, Seung-Hwan Jang, Sang-Wang Lee, Seon-Young Kim, Bora Kwon, Kang-Yeol Yu, Su Young Kim, Dong Kwon Yang
Growing evidence has indicated that supplementation with probiotics improves lipid metabolism. We aimed to investigate the beneficial effects of a probiotics mixture (PM) of three strains belonging to the species Bifidobacterium (B. longum, B. lactis, and B. breve) and two strains belonging to the species Lactobacillus (L. reuteri and L. plantarum) on cholesterol-lowering efficacy in hypercholesterolemic rats. A hypercholesterolemic rat model was established by feeding a high-cholesterol diet for eight weeks...
March 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28299466/development-of-oral-cancer-vaccine-using-recombinant-bifidobacterium-displaying-wilms-tumor-1-protein
#8
Koichi Kitagawa, Tsugumi Oda, Hiroki Saito, Ayame Araki, Reina Gonoi, Katsumi Shigemura, Yoshiko Hashii, Takane Katayama, Masato Fujisawa, Toshiro Shirakawa
Several types of vaccine-delivering tumor-associated antigens (TAAs) have been developed in basic and clinical research. Wilms' tumor 1 (WT1), identified as a gene responsible for pediatric renal neoplasm, is one of the most promising TAA for cancer immunotherapy. Peptide and dendritic cell-based WT1 cancer vaccines showed some therapeutic efficacy in clinical and pre-clinical studies but as yet no oral WT1 vaccine can be administrated in a simple and easy way. In the present study, we constructed a novel oral cancer vaccine using a recombinant Bifidobacterium longum displaying WT1 protein...
March 15, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28297748/bioconversion-using-lactic-acid-bacteria-ginsenosides-gaba-and-phenolic-compounds
#9
REVIEW
Na-Kyoung Lee, Hyun-Dong Paik
Lactic acid bacteria (LAB) are used as fermentation starters in vegetable and dairy products and influence the pH and flavors of foods. For many centuries, LAB have been used to manufacture fermented foods; therefore, they are generally regarded as safe. LAB produce various substances such as lactic acid, β-glucosidase, or β-galactosidase, making them useful as fermentation starters. Existing functional substances have been tried as fermentation substrates for better bioavailability or other functions. Representative materials that were bioconverted using LAB have been reported and include minor ginsenoside, γ-amino butyric acid, equol, aglycone, bioactive isoflavones, genistein, daidzein, and others...
March 15, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28294428/probiotics-and-antimicrobial-protein-and-peptide-levels-in-preterm-infants
#10
Tobias Strunk, Julie Hibbert, Dorota Doherty, Caitlyn Granland, Stephanie Trend, Karen Simmer, David Burgner, Sanjay Patole, Andrew Currie
AIM: To characterise the secreted and inducible antimicrobial protein and peptide (APP) levels in a prospective cohort of preterm infants (<30 weeks gestational age) with or without Bifidobacterium breve M16V supplementation during the first month of life. METHODS: We analysed serial biosamples of infants who did (n=13) or did not receive (n=62) B. breve (3×10(9) cfu/day). Peripheral blood was obtained on days 1, 14 and 28, and infant stool prior to commencement of probiotic supplementation and on day 21...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28286570/strain-specific-probiotic-properties-of-lactic-acid-bacteria-and-their-interference-with-human-intestinal-pathogens-invasion
#11
Raffaella Campana, Saskia van Hemert, Wally Baffone
BACKGROUND: One of the working mechanisms of probiotic bacteria is their ability to compete with pathogens. To define the probiotic properties of seven Lactic Acid Bacteria (LAB) strains, we tested them for survival in simulated gastro-intestinal conditions, antimicrobial activities, co-aggregative abilities, and interferences studies against five human intestinal pathogens (Salmonella enteritidis ATCC 13076, Listeria monocytogenes ATCC 7644, Escherichia coli O157: H7 ATCC 35150, Cronobacter sakazakii ATCC 29544 and Campylobacter jejuni ATCC 33291)...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28286561/systematic-review-and-meta-analysis-the-effects-of-fermented-milk-with-bifidobacterium-lactis-cncm-i-2494-and-lactic-acid-bacteria-on-gastrointestinal-discomfort-in-the-general-adult-population
#12
REVIEW
Jacqui Eales, Peter Gibson, Peter Whorwell, John Kellow, Ann Yellowlees, Richard H J Perry, Mary Edwards, Sarah King, Hannah Wood, Julie Glanville
BACKGROUND: It has been suggested that probiotics may improve gastrointestinal discomfort. Not all probiotics exhibit the same effects and consequently meta-analyses on probiotics should be confined to well-defined strains or strain combinations. The aim of this study was to evaluate the effectiveness of a probiotic fermented milk (PFM) that includes Bifidobacterium lactis (B. lactis) CNCM I-2494 and lactic acid bacteria on gastrointestinal discomfort in the general adult population. METHODS: Double-blind randomized controlled trials in the general adult population comparing PFM with a control dairy product for at least 4 weeks were searched from multiple literature databases (up to February 2015)...
January 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28283459/characterization-of-novel-thermophilic-alpha-glucosidase-from-bifidobacterium-longum
#13
Na-Ri Kim, Da-Woon Jeong, Dam-Seul Ko, Jae-Hoon Shim
In this study, the gene encoding α-glucosidase from Bifidobacterium longum subsp. longum JCM1217 (BLAG) was cloned and expressed in Escherichia coli. The amino acid sequence alignment demonstrated that BLAG belongs to glycoside hydrolase (GH) family 13. The optimal temperature for enzyme activity was 75°C; about 80% of the catalytic activity was lost at 50°C, which is very unusual for enzymes from the Bifidobacterium genus. In the presence of 5mM of Co(2+) and Ca(2+), enzyme activity was reduced to 47% and 48%, respectively...
March 7, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28281639/influence-of-dairy-by-product-waste-milk-on-the-microbiomes-of-different-gastrointestinal-tract-components-in-pre-weaned-dairy-calves
#14
Y F Deng, Y J Wang, Y Zou, A Azarfar, X L Wei, S K Ji, J Zhang, Z H Wu, S X Wang, S Z Dong, Y Xu, D F Shao, J X Xiao, K L Yang, Z J Cao, S L Li
The community structure of colonised bacteria in the gastrointestinal tracts (GITs) of pre-weaned calves is affected by extrinsic factors, such as the genetics and diet of the calves; however, the dietary impact is not fully understood and warrants further research. Our study revealed that a total of 6, 5, 2 and 10 bacterial genera showed biologically significant differences in the GITs of pre-weaned calves fed four waste-milk diets: acidified waste milk, pasteurised waste milk, untreated bulk milk, and untreated waste milk, respectively...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28280022/complete-genome-sequence-of-bifidobacterium-longum-w11-lmg-p-21586-used-as-a-probiotic-strain
#15
Rosanna Inturri, Marco Ventura, Patricia Ruas-Madiedo, Gabriele Andrea Lugli, Giovanna Blandino
We report the complete genome sequence of Bifidobacterium longum W11 (LMG P-21586) isolated from the intestinal microbiota of a healthy man. The analysis of the sequence may provide insights into the microbiological characteristics and the functional activity of this probiotic strain.
March 9, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28273274/effects-of-probiotic-intake-on-intestinal-bifidobacteria-of-celiac-patients
#16
Flávia Martinello, Camila Fontana Roman, Paula Alves de Souza
BACKGROUND: Healthy individuals exhibit a significantly higher concentration of faecal bifidobacteria in comparison to celiac patients. Even though there are potential benefits in probiotic usage, they have been little explored as an adjunctive therapy in celiac disease. OBJECTIVE: This study aimed at the comparison of faecal bifidobacteria concentration and pH among celiac patients and healthy subjects before and after the daily intake of 100 g of yogurt containing probiotic for a thirty-day period...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28272161/association-of-maternal-gestational-weight-gain-with-the-infant-fecal-microbiota
#17
Alyssa Robinson, Lauren Fiechtner, Brianna Roche, Nadim J Ajami, Joseph F Petrosino, Carlos A Camargo, Elsie M Taveras, Kohei Hasegawa
OBJECTIVES: Pregnancy characteristics may influence the infant fecal microbiota during early life. We aimed to examine associations of maternal gestational weight gain with infant fecal microbiota composition, bacterial community richness, and Shannon diversity index. METHODS: We analyzed data from a prospective cohort study of healthy infants. We collected prenatal data, including report of mother's gestational weight gain, and infant fecal samples from 84 infant-mother dyads...
March 7, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28270216/bifidobacterium-mixture-b-longum-bb536-b-infantis-m-63-b-breve-m-16v-treatment-in-children-with-seasonal-allergic-rhinitis-and-intermittent-asthma
#18
Michele Miraglia Del Giudice, Cristiana Indolfi, Michele Capasso, Nunzia Maiello, Fabio Decimo, Giorgio Ciprandi
BACKGROUND: Allergic rhinitis (AR) and allergic asthma are caused by an IgE-mediated inflammatory reaction. Probiotics may exert anti-inflammatory and immune-modulatory activity. Thus, this study aimed at investigating whether a Bifidobacteria mixture could be able to relieve nasal symptoms, and affect quality of life (QoL) in children with AR and intermittent asthma due to Parietaria allergy. MATERIALS AND METHODS: The present study was conducted as placebo-controlled, double-blinded, and randomized...
March 7, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28265110/bifidobacterium-breve-with-%C3%AE-linolenic-acid-alters-the-composition-distribution-and-transcription-factor-activity-associated-with-metabolism-and-absorption-of-fat
#19
Elaine Patterson, Rebecca Wall, Sara Lisai, R Paul Ross, Timothy G Dinan, John F Cryan, Gerald F Fitzgerald, Sebastiano Banni, Eamonn M Quigley, Fergus Shanahan, Catherine Stanton
This study focused on the mechanisms that fatty acid conjugating strains - Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 - influence lipid metabolism when ingested with α-linolenic acid (ALA) enriched diet. Four groups of BALB/c mice received ALA enriched diet (3% (w/w)) either alone or in combination with B. breve NCIMB 702258 or B. breve DPC 6330 (10(9) CFU/day) or unsupplemented control diet for six weeks. The overall n-3 PUFA score was increased in all groups receiving the ALA enriched diet...
March 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28260061/subgingival-dysbiosis-in-smoker-and-non%C3%A2-smoker-patients-with-chronic-periodontitis
#20
Lorena Coretti, Mariella Cuomo, Ermanno Florio, Domenico Palumbo, Simona Keller, Raffaela Pero, Lorenzo Chiariotti, Francesca Lembo, Carlo Cafiero
Periodontitis is one of the most common oral inflammatory diseases, and results in connective tissue degradation and gradual tooth loss. It manifests with formation of periodontal pockets, in which anaerobic and Gram‑negative bacteria proliferate rapidly. Consequently, alteration of the subgingival microbiota is considered the primary etiologic agent of periodontitis. Previous studies have reported that smokers are at increased risk of periodontal disease, in both prevalence and severity, indicating that smoking is a risk factor for the onset and progression of the pathology...
March 1, 2017: Molecular Medicine Reports
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