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https://www.readbyqxmd.com/read/29785540/use-of-magnetic-resonance-imaging-in-rectal-cancer-patients-society-of-abdominal-radiology-sar-rectal-cancer-disease-focused-panel-dfp-recommendations-2017
#1
Marc J Gollub, Supreeta Arya, Regina Gh Beets-Tan, Gregory dePrisco, Mithat Gonen, Kartik Jhaveri, Zahra Kassam, Harmeet Kaur, David Kim, Andrea Knezevic, Elena Korngold, Chandana Lall, Neeraj Lalwani, D Blair Macdonald, Courtney Moreno, Stephanie Nougaret, Perry Pickhardt, Shannon Sheedy, Mukesh Harisinghani
PURPOSE: To propose guidelines based on an expert-panel-derived unified approach to the technical performance, interpretation, and reporting of MRI for baseline and post-treatment staging of rectal carcinoma. METHODS: A consensus-based questionnaire adopted with permission and modified from the European Society of Gastrointestinal and Abdominal Radiologists was sent to a 17-member expert panel from the Rectal Cancer Disease-Focused Panel of the Society of Abdominal Radiology containing 268 question parts...
May 21, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29785457/a-novel-method-of-intracorporeal-end-to-end-gastrogastrostomy-in-laparoscopic-pylorus-preserving-gastrectomy-for-early-gastric-cancer-including-a-unique-anastomotic-technique-piercing-the-stomach-with-a-linear-stapler
#2
Manabu Ohashi, Naoki Hiki, Satoshi Ida, Koshi Kumagai, Souya Nunobe, Takeshi Sano
BACKGROUND: Delta-shaped anastomosis is usually applied for an intracorporeal gastrogastrostomy in totally laparoscopic pylorus-preserving gastrectomy (TLPPG). However, the remnant stomach is slightly twisted around the anastomosis because it connects in side-to-side fashion. To realize an intracorporeal end-to-end gastrogastrostomy using an endoscopic linear stapler, we invented a novel method including a unique anastomotic technique. MATERIALS AND METHODS: In this new approach, we first made small gastrotomies at the greater and lesser curvatures of the transected antrum and then pierced it using an endoscopic linear stapler...
May 21, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29785173/phytochemicals-that-influence-gut-microbiota-as-prophylactics-and-for-the-treatment-of-obesity-and-inflammatory-diseases
#3
REVIEW
Lucrecia Carrera-Quintanar, Rocío I López Roa, Saray Quintero-Fabián, Marina A Sánchez-Sánchez, Barbara Vizmanos, Daniel Ortuño-Sahagún
Gut microbiota (GM) plays several crucial roles in host physiology and influences several relevant functions. In more than one respect, it can be said that you "feed your microbiota and are fed by it." GM diversity is affected by diet and influences metabolic and immune functions of the host's physiology. Consequently, an imbalance of GM, or dysbiosis, may be the cause or at least may lead to the progression of various pathologies such as infectious diseases, gastrointestinal cancers, inflammatory bowel disease, and even obesity and diabetes...
2018: Mediators of Inflammation
https://www.readbyqxmd.com/read/29784753/use-of-direct-oral-anticoagulants-for-treating-venous-thromboembolism-in-patients-with-cancer
#4
Gerald A Soff
For patients with cancer who experience venous thromboembolism (VTE), low-molecular-weight heparin (LMWH) remains the standard of care in the NCCN Guidelines for VTE, but under certain conditions direct oral anticoagulants (DOACs) are acceptable alternatives. A growing body of literature suggests that DOACs may more effective than LMWHs in preventing recurrences, but they do carry some increased risk of bleeding. Most of this risk is seen in patients with gastrointestinal or urinary pathology or implanted devices...
May 2018: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29783000/controlling-nutritional-status-score-a-promising-prognostic-marker-in-patients-with-gastrointestinal-cancers-after-surgery-a-systematic-review-and-meta-analysis
#5
REVIEW
Yi Zhang, Xu Zhang
BACKGROUND: Controlling nutritional status (CONUT) score has been reported to correlate with gastrointestinal (GI) cancer prognosis, but the results remain inconsistent. This study was to synthetically determine the associations between CONUT score and prognosis in GI cancers. METHODS: Online databases PubMed, Web of Science, Cochrane library, Embase, Google scholar, Wanfang and National Knowledge Infrastructure (CNKI) were searched for eligible articles published prior to March 10, 2018...
May 18, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29782365/utilization-of-an-alternative-docetaxel-based-intraperitoneal-chemotherapy-regimen-in-patients-with-ovarian-fallopian-tube-or-primary-peritoneal-carcinoma-a-continued-need-for-ovarian-cancer-patients
#6
David A Becker, Charles A Leath, Christen L Walters-Haygood, Brentley Q Smith, Kerri S Bevis
OBJECTIVE: The objective of this study was to report the tolerability and toxicity of a regimen consisting of intravenous (IV) docetaxel and intraperitoneal (IP) cisplatin and paclitaxel with granulocyte colony-stimulating factor support. MATERIALS AND METHODS: We conducted a retrospective cohort study of patients with surgical stage II-IV epithelial ovarian, fallopian tube or primary peritoneal carcinoma treated with an outpatient IP chemotherapy regimen consisting of docetaxel 75 mg/m IV and cisplatin 75 mg/m IP day 1 followed by paclitaxel 60 mg/m IP day 8 every 21 days...
May 18, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29781255/combination-therapy-of-canine-osteosarcoma-with-canine-bone-marrow-stem-cells-bone-morphogenetic-protein-and-carboplatin-in-an-in-vivo-model
#7
R E G Rici, S E A L Will, A C L Luna, L F Melo, A C Santos, R F Rodrigues, R M Leandro, D A Maria
Osteosarcoma (OSA) is the most common malignant bone cancer in children and dogs. The therapeutic protocols adopted for dogs and humans are very similar, involving surgical options such as amputation. Besides surgical options, radiotherapy and chemotherapy also are adopted. However, hematologic, gastrointestinal and renal toxicity may occur because of chemotherapy treatments. Recent study clearly showed that mesenchymal stem cells (MSCs) combined with recombinant human bone morphogenetic protein (rhBMP-2) may be associated with decreases of the tumorigenic potential of canine OSA...
May 20, 2018: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29780653/isolated-superior-mesenteric-vein-tumor-thrombus-in-a-patient-with-gastric-cancer
#8
Barış Özcan, Metin Çevener, Ayşegül Kargı, Mustafa Özdoğan, Alihan Gürkan
Tumor thrombus in the portal vein can rarely originate from gastric cancer via hematogenous spread, with only few case reports published in the literature. Isolated superior mesenteric vein tumor thrombus in gastric cancer has not been previously reported. A 61-year-old male patient who had undergone distal gastrectomy and gastroenterostomy for gastric ulcer 20 years ago was diagnosed with an obstructive tumor originating from the gastroenterostomy anastomosis site on upper gastrointestinal endoscopy that was performed for complaints of fatigue, oral feeding problems, and anemia...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29779818/fighting-obesity-non-pharmacological-interventions
#9
María Fernanda Higuera-Hernández, Elena Reyes-Cuapio, Marissa Gutiérrez-Mendoza, Nuno Barbosa Rocha, André Barciela Veras, Henning Budde, Johanna Jesse, Jaime Zaldívar-Rae, Carlos Blanco-Centurión, Sérgio Machado, Eric Murillo-Rodríguez
The abnormal or excessive fat accumulation that impairs health is one of the criteria that fulfills obesity. According to epidemiological data, obesity has become a worldwide public health problem that in turn would trigger additional pathologies such as cardiorespiratory dysfunctions, cancer, gastrointestinal disturbances, depression, sleep disorders, just to mention a few. Then, the search for a therapeutical intervention aimed to prevent and manage obesity has been the focus of study during the last years...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779814/should-omega-3-fatty-acids-be-used-for-adjuvant-treatment-of-cancer-cachexia
#10
REVIEW
Daryna Sergiyivna Lavriv, Pedro Miguel Neves, Paula Ravasco
OBJECTIVES: Cancer cachexia is characterised by a progressive loss of muscle, resulting in functional impairment and shorter survival. Therefore, omega-3 has been studied for its role as an anti-cachectic therapy. This systematic review identified studies published on use of omega-3 in cancer cachexia in order to examine the potential benefit. METHODS: A systematic review of the literature using PubMed and B-on databases was conducted to identify clinical trials published between 2000 and 2015, to evaluate the effect of n-3 PUFAs on nutritional features and Quality of Life in cancer cachexia...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779004/cancer-incidence-among-merchant-seafarers-an-extended-follow-up-of-a-danish-cohort
#11
Kajsa Ugelvig Petersen, Julie Volk, Linda Kaerlev, Henrik Lyngbeck Hansen, Johnni Hansen
OBJECTIVES: While maritime safety generally has improved dramatically over the last century, modern seafarers are still faced with numerous occupational hazards potentially affecting their risk of chronic diseases such as cancer. The aim of this study is to offer updated information on the incidence of specific cancers among both male and female seafarers. METHODS: Using records from the Danish Seafarer Registry, all seafarers employed on Danish ships during 1986-1999 were identified, resulting in a cohort of 33 084 men and 11 209 women...
May 19, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29778550/the-factors-associated-with-negative-colonoscopy-in-screening-subjects-with-positive-immunochemical-stool-occult-blood-test-outcomes
#12
Po-Hsiang Ting, Xi-Hsuan Lin, Jeng-Kai Jiang, Jiing-Chyuan Luo, Ping-Hsien Chen, Yen-Po Wang, I-Fang Hsin, Chin Lin Perng, Ming-Chih Hou, Fa-Yauh Lee
BACKGROUND: The immunochemical fecal occult blood test (iFOBT) is an alternative method to colonoscopy that can be used for colorectal cancer (CRC) screening. If the iFOBT result is positive, a colonoscopy is recommended. In this retrospective study, we identify factors associated with negative colonoscopy and positive iFOBT results obtained during CRC screening. METHODS: We collected data for subjects who received a colonoscopy at Taipei Veterans General Hospital after receiving a positive iFOBT result during CRC screening from January 2015 to December 2015...
May 16, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29777533/combination-of-apatinib-and-continuous-nutritional-support-for-a-gastric-cancer-patient-with-brain-metastasis-prolongs-survival
#13
Y Yang, X Pei, M Yang
WHAT IS KNOWN AND OBJECTIVES: Gastric cancer is the most common gastrointestinal malignant tumour in China, which rarely metastasizes into the central nervous system. However, brain metastasis leads to increased risk of death. CASE SUMMARY: Here, we report a case of brain metastasis from gastric cancer, which was treated with apatinib and continual nutritional support, with a survival time of 2 years. WHAT IS NEW AND CONCLUSION: The combination of apatinib and continual nutritional support may be an option for the treatment of brain metastasis from gastric cancer...
May 18, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29777378/characterization-of-low-active-ghrelin-ratio-in-patients-with-advanced-pancreatic-cancer
#14
Tomofumi Miura, Shuichi Mitsunaga, Masafumi Ikeda, Izumi Ohno, Hideaki Takahashi, Hidetaka Suzuki, Ai Irisawa, Takeshi Kuwata, Atsushi Ochiai
PURPOSE: Acyl ghrelin is an orexigenic peptide. Active ghrelin ratio, the ratio of acyl ghrelin to total ghrelin, has an important role in physiological functions and gastrointestinal symptoms. However, low active ghrelin ratio-related characteristics, gastrointestinal symptoms, and chemotherapy-induced gastrointestinal toxicity in patients with advanced pancreatic cancer have not been previously evaluated. The goal of this study was to identify low active ghrelin ratio-related factors in treatment-naïve advanced pancreatic cancer patients...
May 18, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29776346/a-systematic-review-of-the-risk-factors-for-clinical-response-to-opioids-for-all-age-patients-with-cancer-related-pain-and-presentation-of-the-paediatric-stop-pain-study
#15
Ersilia Lucenteforte, Laura Vagnoli, Alessandra Pugi, Giada Crescioli, Niccolò Lombardi, Roberto Bonaiuti, Maurizio Aricò, Sabrina Giglio, Andrea Messeri, Alessandro Mugelli, Alfredo Vannacci, Valentina Maggini
BACKGROUND: Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. The STOP Pain project aimed to evaluate the risk factors that contribute to clinical response and adverse drug reactions to opioids by means of a systematic review and a clinical investigation on paediatric oncological patients. METHODS: We conducted a systematic literature search in EMBASE and PubMed up to the 24th of November 2016 following Cochrane Handbook and PRISMA guidelines...
May 18, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29775693/comparison-of-coping-psychological-distress-and-level-of-functioning-in-patients-with-gastric-and-colorectal-cancer-prior-to-adjuvant-chemotherapy
#16
Caterina Calderón, Paula Jimenez-Fonseca, Carlos Jara, Raquel Hernández, Eva Martínez de Castro, Sonal Varma, Ismael Ghanem, Alberto Carmona-Bayonas
CONTEXT-: Patients with gastrointestinal cancers are at high risk for functional problems that are generally accompanied by a decline in their overall status and intense psychological distress. OBJECTIVES: This study compares the level of functioning in individuals with gastric cancer (GC) and colorectal cancer (CRC) and analyzes whether improved functioning can be explained by patients' psychological status and coping strategies. METHODS: Prospective, transversal, multicenter study in patients with non-metastatic GC and CRC prior to initiating adjuvant chemotherapy...
May 15, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29774938/-analysis-of-risk-factors-of-prolonged-postoperative-ileus-after-gastric-cancer-surgery
#17
Ning Wang, Lin Chen, Mingsen Li, Naizhong Jin, Bo Wei
OBJECTIVE: To investigate the risk factors of prolonged postoperative ileus (PPOI) after gastric cancer surgery. METHODS: Definition of PPOI was that gastrointestinal function did not return to normal within 96 hours after operation. Diagnostic criteria of PPOI were as follows: according with over 2 below conditions at postoperative 97-hour: (1) moderate to severe sick (mild: 1-3 points, moderate: 4-7 points, severe: 8-10 points) or vomiting occurred in past 12 hours...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774937/-application-of-robotic-surgery-to-treat-carcinoma-in-the-remnant-stomach
#18
Feng Qian, Jiajia Liu, Junyan Liu, Junyan Fan, Yongliang Zhao, Yan Shi, Yingxue Hao, Peiwu Yu
OBJECTIVE: To explore the surgical techniques and feasibility of robotic surgery for carcinoma in the remnant stomach(CRS). METHODS: Clinicopathological data of 20 CRS patients undergoing robotic surgery at the Minimally Invasive Center for Gastrointestinal Surgery, Army Medical University Southwest Hospital from November 2012 to October 2017 were retrospectively collected. The surgical methods, procedures, main difficulties, and key techniques were analyzed, and the clinical efficacy was evaluated...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774935/-clinicopathological-characteristics-and-prognosis-analysis-of-217-patients-with-carcinoma-in-the-remnant-stomach
#19
Xiaodong Liu, Zhaojian Niu, Dong Chen, Dongsheng Wang, Liang Lyu, Haitao Jiang, Jian Zhang, Yu Li, Shougen Cao, Yanbing Zhou
OBJECTIVE: To evaluate the clinicopathological features and prognostic factors of carcinoma in the remnant stomach (CRS). METHODS: Clinicopathological data of 217 consecutive CRS patients from January 2000 to March 2017 at Department of Gastrointestinal Surgery, The Affiliated Hospital of Qingdao University were retrospectively analyzed. CRS was defined as the primary cancer arising from the remnant stomach following gastrectomy, regardless of the initial disease or operation, and at no special time interval...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774933/-clinicopathological-characteristics-and-prognostic-factor-analysis-of-carcinoma-in-remnant-stomach-cancer-at-peking-university-cancer-hospital
#20
Yinkui Wang, Ziyu Li, Chenggen Jin, Xiangji Ying, Chao Gao, Yuchen Wang, Qiyan Xiao, Yan Zhang, Yufan Chen, Lianhai Zhang, Jiafu Ji
OBJECTIVE: To investigate the interval time to canceration, clinicopathological characteristics and prognostic factors of carcinoma in remnant stomach (CRS) in patients with primary benign diseases or primary malignant tumors. METHODS: Based on the criteria of the definition of CRS proposed by Japanese Gastric Cancer Association in 2017, a retrospective analysis was conducted on clinicopathological characteristics of patients diagnosed with CRS at Peking University Cancer Hospital from March 1992 to March 2017...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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