keyword
https://read.qxmd.com/read/38492231/co-design-of-an-intervention-to-improve-patient-participation-in-discharge-medication-communication
#21
JOURNAL ARTICLE
Georgia Tobiano, Sharon Latimer, Elizabeth Manias, Andrea P Marshall, Megan Rattray, Kim Jenkinson, Trudy Teasdale, Kellie Wren, Wendy Chaboyer
Patients can experience medication-related harm and hospital readmission because they do not understand or adhere to post-hospital medication instructions. Increasing patient medication literacy and, in turn, participation in medication conversations could be a solution. The purposes of this study were to co-design and test an intervention to enhance patient participation in hospital discharge medication communication. In terms of methods, co-design, a collaborative approach where stakeholders design solutions to problems, was used to develop a prototype medication communication intervention...
March 16, 2024: International Journal for Quality in Health Care
https://read.qxmd.com/read/38492092/comparison-of-the-efficacy-and-safety-of-benzbromarone-and-febuxostat-in-gout-and-hyperuricemia-a-systematic-review-and-meta-analysis
#22
JOURNAL ARTICLE
Fan Wu, Lvyi Chen, Yimei Du
OBJECTIVE: Urate-lowering therapy (ULT) is widely recognized as the primary treatment for hyperuricemia and gout. Xanthine oxidase inhibitors (XOI), particularly febuxostat, have gained popularity as a frontline approach. However, the divergent efficacy and safety between febuxostat and the traditional ULT drug, benzbromarone, remain poorly understood. This knowledge gap necessitates a comprehensive analysis and evidence update to guide drug selection for physicians and patients. METHOD: We conducted a systematic analysis by extracting relevant clinical studies from four medical literature databases...
March 16, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38491975/seizure-provocation-in-eeg-recordings-a-data-driven-approach
#23
JOURNAL ARTICLE
Pirgit Meritam Larsen, Stephan Wüstenhagen, Daniella Terney, Elena Gardella, Harald Aurlien, Sándor Beniczky
OBJECTIVE: Recording seizures on video-EEG has a high diagnostic value. However, bilateral convulsive seizures constitute a risk for the patients. Our aim was to investigate the diagnostic yield and associated risks of provocation methods in short-term video-EEGs. METHODS: We extracted data on seizures and provocation methods from a large database of short-term video-EEGs with standardized annotations using SCORE (Standardized Computer-based Organized reporting of EEG)...
March 16, 2024: Epileptic Disorders: International Epilepsy Journal with Videotape
https://read.qxmd.com/read/38491885/a-study-of-the-use-of-medicinal-plants-by-persons-with-type-2-diabetes-in-iran
#24
JOURNAL ARTICLE
Mojtaba Fattahi Ardakani, Arash Salahshouri, Ahmad Sotoudeh, Mohammad Rafati Fard, Saeed Dashti, Hadi Ahmadi Chenari, Steven L Baumann
Medicinal plants are used by many people with Type 2 diabetes in Iran. The aim of this study was to explore why this is so, from their perspective. Sixteen persons with Type 2 diabetes in Yazd City, Iran, were interviewed in April and May 2020 for this study. A thematic analysis of the transcripts of those interviews was done using MAXQDA 10 software. Six themes were identified: beliefs about medicinal plants, psychological factors, accessibility and economic barriers, patients' knowledge and awareness, social pressure, and the role of family culture...
April 2024: Nursing Science Quarterly
https://read.qxmd.com/read/38491850/mammalian-diaphanous1-signalling-in-neurovascular-complications-of-diabetes
#25
JOURNAL ARTICLE
Julia Jarosławska, Bernard Kordas, Tadeusz Miłowski, Judyta K Juranek
Over the past few decades, diabetes gradually has become one of the top non-communicable disorders, affecting 476.0 million in 2017 and is predicted to reach 570.9 million people in 2025. It is estimated that 70 to 100% of all diabetic patients will develop some if not all, diabetic complications over the course of the disease. Despite different symptoms, mechanisms underlying the development of diabetic complications are similar, likely stemming from deficits in both neuronal and vascular components supplying hyperglycaemia-susceptible tissues and organs...
March 16, 2024: European Journal of Neuroscience
https://read.qxmd.com/read/38491840/home-versus-hospital-rehabilitation-of-older-adults-following-hip-fracture-yields-similar-patient-reported-outcome-measures
#26
JOURNAL ARTICLE
Hanna S Schroeder, Avi Israeli, Meir Iri Liebergall, Omer Or, Wiessam Abu Ahmed, Ora Paltiel, Dan Justo, Eyal Zimlichman
The increase in hip fractures (HF) due to aging of the population and the rise in attractiveness of services provided at home following the COVID-19 pandemic, emphasize the need to compare outcomes of home versus hospital HF rehabilitation. To date, studies comparing the 2 services have focused primarily on clinical outcomes rather than patient-reported outcomes (PROs). This longitudinal observational study evaluated PROs of older adults with HF in the 2 settings. The SF36 questionnaire was used to measure PROs 3 times after surgery...
2024: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://read.qxmd.com/read/38491748/permanent-junctional-reciprocating-tachycardia-due-to-an-atypical-retrograde-slow-conducting-decremental-left-posterolateral-accessory-pathway-and-tachycardia-induced-cardiomyopathy-in-a-pregnant-adolescent
#27
Utkarsh Kohli, Sohail Hassan, Christopher Mercer, Larry Rhodes
Permanent junctional reciprocating tachycardia (PJRT) is a rare form of supraventricular tachycardia (SVT) due to a retrograde slow conducting decremental accessory pathway (AP) which is often incessant and can lead to tachycardia-induced cardiomyopathy (TIC). We report the challenging clinical course of a pregnant adolescent with PJRT due to an atypical retrograde slow conducting decremental left posterolateral AP. Pregnancy is known to exacerbate supraventricular arrhythmias and can lead to adverse maternal and fetal outcomes...
March 15, 2024: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/38491737/knowledge-attitude-and-practice-toward-postoperative-self-management-among-patients-after-percutaneous-coronary-intervention-a-structural-equation-modeling-analysis
#28
JOURNAL ARTICLE
Hailing Lei, Lin Zhu, Xin Zhang
OBJECTIVE: The knowledge, attitude, and practice (KAP) toward post-percutaneous coronary intervention (PCI) self-management among Chinese patients remains unknown. This study investigated the KAP toward postoperative self-management among patients after PCI. HYPOTHESIS: Patients exhibit poor knowledge, attitudes, and practices regarding post-PCI self-management, requiring enhanced education strategies. METHODS: This cross-sectional study recruited patients after PCI at Jishuitan Hospital, Beijing, between November 2022 and May 2023...
March 2024: Clinical Cardiology
https://read.qxmd.com/read/38491526/the-spleen-is-the-graveyard-of-cd4-cells-in-patients-with-immunological-failure-of-visceral-leishmaniasis-and-aids
#29
JOURNAL ARTICLE
Luis Gustavo Cavalcante Reinaldo, Raimundo José Cunha Araújo Júnior, Thiago Melo Diniz, Rafael de Deus Moura, Antônio José Meneses Filho, Caio Victor Verçosa de Macedo Furtado, Washington Luis Conrado Dos Santos, Dorcas Lamounier Costa, Kelsen Dantas Eulálio, Gabriel R Ferreira, Carlos Henrique Nery Costa
BACKGROUND: Visceral leishmaniasis (VL), or kala-azar, is a common comorbidity in patients with AIDS in endemic areas. Many patients continue to experiences relapses of VL despite virological control, but with immunological failure. These patients remain chronically symptomatic with hypersplenism, for example with anemia, leukopenia, and thrombocytopenia, and are at risk of severe co-infection due to low CD4+ count. Therefore, in this study, splenectomized patients with VL and HIV infection were investigated to understand why the CD4+ count fails to recover in these patients, evaluating the importance of spleen mass for hypersplenism and immunological failure...
March 15, 2024: Parasites & Vectors
https://read.qxmd.com/read/38491495/liver-injury-in-covid-19-an-insight-into-pathobiology-and-roles-of-risk-factors
#30
REVIEW
Abbas Tazarghi, Sahar Bazoq, Mohammad Hosein Taziki Balajelini, Mohsen Ebrahimi, Seyed Mehran Hosseini, Hadi Razavi Nikoo
COVID-19 is a complex disease that can lead to fatal respiratory failure with extrapulmonary complications, either as a direct result of viral invasion in multiple organs or secondary to oxygen supply shortage. Liver is susceptible to many viral pathogens, and due to its versatile functions in the body, it is of great interest to determine how hepatocytes may interact with SARS-CoV-2 in COVID-19 patients. Liver injury is a major cause of death, and SARS-CoV-2 is suspected to contribute significantly to hepatopathy...
March 15, 2024: Virology Journal
https://read.qxmd.com/read/38491467/a-confirmed-case-of-xylazine-induced-skin-ulcers-in-a-person-who-injects-drugs-in-miami-florida-usa
#31
JOURNAL ARTICLE
Peyton V Warp, Maia Hauschild, David P Serota, Katrina Ciraldo, Irasema Cruz, Tyler S Bartholomew, Hansel E Tookes
BACKGROUND: Xylazine is an alpha-2 adrenergic receptor agonist that has emerged as a contaminant in the illicit drug supply of fentanyl. Xylazine use may be suspected in naloxone-resistant overdoses and atypical, chronic wounds in people who use drugs (PWUD). This case is unique because it is the first case to our knowledge describing wound care for a xylazine-induced wound with a confirmatory xylazine test strip (XTS) in the setting of a syringe services program (SSP) and in the state of Florida...
March 15, 2024: Harm Reduction Journal
https://read.qxmd.com/read/38491463/a-novel-in-bed-body-posture-monitoring-for-decubitus-ulcer-prevention-using-body-pressure-distribution-mapping
#32
JOURNAL ARTICLE
Lindsay Stern, Geoff Fernie, Atena Roshan Fekr
BACKGROUND: Decubitus ulcers are prevalent among the aging population due to a gradual decline in their overall health, such as nutrition, mental health, and mobility, resulting in injury to the skin and tissue. The most common technique to prevent these ulcers is through frequent repositioning to redistribute body pressures. Therefore, the main goal of this study is to facilitate the timely repositioning of patients through the use of a pressure mat to identify in-bed postures in various sleep environments...
March 15, 2024: Biomedical Engineering Online
https://read.qxmd.com/read/38491447/clinical-spectrum-and-long-term-outcomes-of-mpox-a-cohort-study-spanning-from-acute-infection-to-six-month-follow-up
#33
JOURNAL ARTICLE
Christoph Zeyen, Maria Kinberger, Helene Kriedemann, Frieder Pfäfflin, Pinkus Tober-Lau, Leu Huang, Victor Max Corman, Alexander Nast, Leif Erik Sander, Florian Kurth, Ricardo Niklas Werner
BACKGROUND: Cases of mpox have been reported worldwide since May 2022. Limited knowledge exists regarding the long-term course of this disease. To assess sequelae in terms of scarring and quality of life (QoL) in mpox patients 4-6 months after initial infection. METHODS: Prospective observational study on clinical characteristics and symptoms of patients with polymerase chain reaction (PCR)-confirmed mpox, including both outpatients and inpatients. Follow-up visits were conducted at 4-6 months, assessing the Patient and Observer Scar Assessment Scale (POSAS), the Dermatology Life Quality Index (DLQI) and sexual impairment, using a numeric rating scale (NRS) from 0 to 10...
March 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38491433/effect-of-online-infographics-for-enhancing-health-literacy-among-patients-with-type-2-diabetes-in-primary-care-unit-during-the-covid-19-pandemic-a-randomized-controlled-trial
#34
JOURNAL ARTICLE
Suchada Sutthiworapon, Polathep Vichitkunakorn, Kittisakdi Choomalee, Pitchayanont Ngamchaliew
BACKGROUND: Health literacy (HL) in patients with type 2 diabetes mellitus (DM) can help control disease and prevent complications. However, most patients with type 2 DM have inadequate HL; therefore, their HL must be further improved. This study aimed to determine the effects of online infographics on improving HL among patients with type 2 DM. METHODS: This randomized controlled trial was conducted from July 2022 to September 2022, at the primary care unit of Songklanagarind Hospital, Thailand; 30 patients with type 2 DM were randomly assigned to the experimental (n = 15; three types of infographics) and control (n = 15; three types of pamphlets) groups...
March 15, 2024: BMC Prim Care
https://read.qxmd.com/read/38491395/-i-think-my-vagina-is-still-there-women-s-perspectives-on-sexual-function-and-dysfunction-following-radical-cystectomy-for-bladder-cancer-a-qualitative-study
#35
JOURNAL ARTICLE
Rachel Carmen Ceasar, Seyedeh-Sanam Ladi-Seyedian, Domenique Escobar, Jullet Han, Kailyn Koh, Sima Porten, Carissa Chu, Erin E Gould, Sumeet Bhanvadia
BACKGROUND: Women's sexual health after radical cystectomy is an important but poorly understood aspect of bladder cancer survivorship. Dedicated investigation is needed to elucidate patient perceptions on sexual function and dysfunction in this setting. AIMS: In this study we sought to qualitatively examine women's perceptions and experiences of sexual health following radical cystectomy for bladder cancer. METHODS: We conducted one-on-one qualitative telephone interviews with 40 women who underwent radical cystectomy in the past 6 months to 5 years and signed a research consent form to be contacted for future studies...
March 15, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38491369/exploring-treatment-burden-in-people-with-type-2-diabetes-mellitus-a-thematic-analysis-in-china-s-primary-care-settings
#36
JOURNAL ARTICLE
Kai Lin, Mi Yao, Lesley Andrew, Rouyan Li, Yilin Chen, Jacques Oosthuizen, Moira Sim, Yongsong Chen
BACKGROUND: Understanding treatment burden is a critical element to the effective management of Type 2 Diabetes Mellitus (T2DM). The current study aims to address the knowledge gap surrounding treatment burden of T2DM from the patient's perspective in China's primary care settings. METHODS: A narrative review informed the creation of an a priori coding structure to identify aspects of T2DM treatment burden. Focus groups were conducted, employing a maximum variation sampling strategy to select participants from diverse sociodemographic backgrounds across urban, suburban, rural, and remote areas in China...
March 15, 2024: BMC Prim Care
https://read.qxmd.com/read/38491364/defining-clinical-endpoints-in-limb-girdle-muscular-dystrophy-a-grasp-lgmd-study
#37
JOURNAL ARTICLE
Amy Doody, Lindsay Alfano, Jordi Diaz-Manera, Linda Lowes, Tahseen Mozaffar, Katherine D Mathews, Conrad C Weihl, Matthew Wicklund, Man Hung, Jeffrey Statland, Nicholas E Johnson
BACKGROUND: The Limb Girdle Muscular Dystrophies (LGMDs) are characterized by progressive weakness of the shoulder and hip girdle muscles as a result of over 30 different genetic mutations. This study is designed to develop clinical outcome assessments across the group of disorders. METHODS/DESIGN: The primary goal of this study is to evaluate the utility of a set of outcome measures on a wide range of LGMD phenotypes and ability levels to determine if it would be possible to use similar outcomes between individuals with different phenotypes...
March 15, 2024: BMC Neurology
https://read.qxmd.com/read/38491207/extraperitoneal-robot-assisted-laparoscopic-prostatectomy-with-versius-system-single-centre-experience
#38
JOURNAL ARTICLE
F Dibitetto, C Fede Spicchiale, R Castellucci, S Sansalone, A Akhundov, L Defidio, M De Dominicis
INTRODUCTION: Versius Surgical System (CMR Surgical, Cambridge, UK) is a novel tele-operated robotic surgical system designed to assist surgeons for minimally invasive surgery which is gaining momentum in the world of robotic surgery. We describe our single centre experience with Versius and report the advantages and challenges posed by this new robotic system in a series of 53 extraperitoneal robotic assisted laparoscopic prostatectomies (eRALP) for prostate cancer (PCa). MATERIALS AND METHODS: Data of 53 eRALP performed with Versius in our centre were collected and analysed, Descriptive statistics were used to report our results...
March 15, 2024: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/38491073/bone-marrow-inflammation-in-haematological-malignancies
#39
REVIEW
Madelon M E de Jong, Lanpeng Chen, Marc H G P Raaijmakers, Tom Cupedo
Tissue inflammation is a hallmark of tumour microenvironments. In the bone marrow, tumour-associated inflammation impacts normal niches for haematopoietic progenitor cells and mature immune cells and supports the outgrowth and survival of malignant cells residing in these niche compartments. This Review provides an overview of our current understanding of inflammatory changes in the bone marrow microenvironment of myeloid and lymphoid malignancies, using acute myeloid leukaemia and multiple myeloma as examples and highlights unique and shared features of inflammation in niches for progenitor cells and plasma cells...
March 15, 2024: Nature Reviews. Immunology
https://read.qxmd.com/read/38491028/relationship-between-social-cognition-and-premorbid-adjustment-in-psychosis-a-systematic-review
#40
REVIEW
P Punsoda-Puche, A Barajas, M Mamano-Grande, A Jiménez-Lafuente, S Ochoa
This systematic review provides a comprehensive overview of the association between premorbid adjustment and social cognition in people with psychotic spectrum disorder. Obtaining evidence of this association will facilitate early detection and intervention before the onset of psychosis. Literature searches were conducted in Scopus, PubMed and PsycINFO. Studies were eligible if they included patients with a psychotic disorder or at a high-risk state; social cognition and premorbid adjustment were measured; and the relationship between premorbid adjustment and social cognition was analysed...
March 15, 2024: Schizophrenia (Heidelb)
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