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VPH clinic case

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https://www.readbyqxmd.com/read/29562466/-the-molecular-cytogenetic-characterization-and-tyrosine-kinase-inhibitors-efficacy-in-newly-diagnosed-chronic-phase-cml-patients-with-variant-philadelphia-chromosomes
#1
J J Zhao, Y L Zhang, S J Zhang, J Zhou, F K Yu, Y L Zu, H F Zhao, Z Li, Y P Song
Objective: To investigate the molecular-cytogenetic characterization and impact on tyrosine kinase inhibitors (TKIs) therapy in chronic phase of chronic myeloid leukemia (CML-CP) patients with variant Ph chromosome (vPh). Methods: The clinical data of 32 patients with vPh chromosomes were collected and compared with 703 patients with typical Ph chromosome in newly diagnosed CML-CP who were on first-line imatinib (IM) and with BCR-ABL transcript of P210. Results: There was no significant difference in demographic and hematological characteristics between vPh and classic Ph patients...
March 14, 2018: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29285342/a-study-on-the-predictability-of-acute-lymphoblastic-leukaemia-response-to-treatment-using-a-hybrid-oncosimulator
#2
Eleftherios Ouzounoglou, Eleni Kolokotroni, Martin Stanulla, Georgios S Stamatakos
Efficient use of Virtual Physiological Human (VPH)-type models for personalized treatment response prediction purposes requires a precise model parameterization. In the case where the available personalized data are not sufficient to fully determine the parameter values, an appropriate prediction task may be followed. This study, a hybrid combination of computational optimization and machine learning methods with an already developed mechanistic model called the acute lymphoblastic leukaemia (ALL) Oncosimulator which simulates ALL progression and treatment response is presented...
February 6, 2018: Interface Focus
https://www.readbyqxmd.com/read/15256825/increased-frequency-of-bacterial-vaginosis-and-chlamydia-trachomatis-in-pregnant-women-with-human-papillomavirus-infection
#3
Cléber Sérgio da Silva, Sheila Jorge Adad, Maria Azniv Hazarabedian de Souza, Ana Cristina Macêdo Barcelos, Ana Paula Sarreta Terra, Eddie Fernando Candido Murta
The aim of this study was to verify the presence of bacterial vaginosis (BV), Candida sp, Chlamydia trachomatis, Neisseria gonorrhoeae, to determine the prevalence of tobacco use and measure vaginal pH (VpH) in pregnant women with (n = 26) and without (n = 26) human papillomavirus (HPV) infection, and make comparisons between these 2 groups. HPV, C. trachomatis and N. gonorrhoeae were diagnosed using hybrid capture, BV using clinical criteria, and Candida sp via cultures. A digital pH meter was used to measure VpH...
2004: Gynecologic and Obstetric Investigation
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