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https://www.readbyqxmd.com/read/28227613/sleep-stage-classification-by-non-contact-vital-signs-indices-using-doppler-radar-sensors
#1
Masayuki Kagawa, Kazuki Suzumura, Takemi Matsui, Masayuki Kagawa, Kazuki Suzumura, Takemi Matsui, Kazuki Suzumura, Takemi Matsui, Masayuki Kagawa
Disturbed sleep has become more common in recent years. To improve the quality of sleep, undergoing sleep observation has gained interest as a means to resolve possible problems. In this paper, we evaluate a non-restrictive and non-contact method for classifying real-time sleep stages and report on its potential applications. The proposed system measures heart rate (HR), heart rate variability (HRV), body movements, and respiratory signals of a sleeping person using two 24-GHz microwave radars placed beneath the mattress...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226824/tunable-somatosensory-stimulation-for-selective-sleep-restriction-studies-in-rodents
#2
Dillon M Huffman, Kendra E Staggs, Farid Yaghouby, Anuj Agarwal, Bruce F O'Hara, Kevin D Donohue, Eric M Blalock, Sridhar Sunderam, Dillon M Huffman, Kendra E Staggs, Farid Yaghouby, Anuj Agarwal, Bruce F O'Hara, Kevin D Donohue, Eric M Blalock, Sridhar Sunderam, Eric M Blalock, Bruce F O'Hara, Kevin D Donohue, Kendra E Staggs, Sridhar Sunderam, Anuj Agarwal, Dillon M Huffman, Farid Yaghouby
Many methods for sleep restriction in rodents have emerged, but most are intrusive, lack fine control, and induce stress. Therefore, a versatile, non-intrusive means of sleep restriction that can alter sleep in a controlled manner could be of great value in sleep research. In previous work, we proposed a novel system for closed-loop somatosensory stimulation based on mechanical vibration and applied it to the task of restricting Rapid Eye Movement (REM) sleep in mice [1]. While this system was effective, it was a crude prototype and did not allow precise control over the amplitude and frequency of stimulation applied to the animal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28220472/renal-denervation-for-resistant-hypertension
#3
REVIEW
Giuseppe Coppolino, Anna Pisano, Laura Rivoli, Davide Bolignano
BACKGROUND: Resistant hypertension is highly prevalent among the general hypertensive population and the clinical management of this condition remains problematic. Different approaches, including a more intensified antihypertensive therapy, lifestyle modifications, or both, have largely failed to improve patients' outcomes and to reduce cardiovascular and renal risk. As renal sympathetic hyperactivity is a major driver of resistant hypertension, renal sympathetic ablation (renal denervation) has been recently proposed as a possible therapeutic alternative to treat this condition...
February 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28210999/computational-cognitive-modeling-of-the-temporal-dynamics-of-fatigue-from-sleep-loss
#4
Matthew M Walsh, Glenn Gunzelmann, Hans P A Van Dongen
Computational models have become common tools in psychology. They provide quantitative instantiations of theories that seek to explain the functioning of the human mind. In this paper, we focus on identifying deep theoretical similarities between two very different models. Both models are concerned with how fatigue from sleep loss impacts cognitive processing. The first is based on the diffusion model and posits that fatigue decreases the drift rate of the diffusion process. The second is based on the Adaptive Control of Thought - Rational (ACT-R) cognitive architecture and posits that fatigue decreases the utility of candidate actions leading to microlapses in cognitive processing...
February 16, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28210319/physiology-of-respiratory-disturbances-in-muscular-dystrophies
#5
Antonella Lo Mauro, Andrea Aliverti
: Muscular dystrophy is a group of inherited myopathies characterised by progressive skeletal muscle wasting, including of the respiratory muscles. Respiratory failure, i.e. when the respiratory system fails in its gas exchange functions, is a common feature in muscular dystrophy, being the main cause of death, and it is a consequence of lung failure, pump failure or a combination of the two. The former is due to recurrent aspiration, the latter to progressive weakness of respiratory muscles and an increase in the load against which they must contract...
December 2016: Breathe
https://www.readbyqxmd.com/read/28208688/the-impact-of-heat-exposure-and-sleep-restriction-on-firefighters-work-performance-and-physiology-during-simulated-wildfire-suppression
#6
Grace E Vincent, Brad Aisbett, Brianna Larsen, Nicola D Ridgers, Rod Snow, Sally A Ferguson
This study was designed to examine the effects of ambient heat on firefighters' physical task performance, and physiological and perceptual responses when sleep restricted during simulated wildfire conditions. Thirty firefighters were randomly allocated to the sleep restricted (n = 17, SR; 19 °C, 4-h sleep opportunity) or hot and sleep restricted (n = 13, HOT + SR; 33 °C, 4-h sleep opportunity) condition. Firefighters performed two days of simulated, intermittent, self-paced work circuits comprising six firefighting tasks...
February 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28193862/differential-modulation-of-global-and-local-neural-oscillations-in-rem-sleep-by-homeostatic-sleep-regulation
#7
Bowon Kim, Bernat Kocsis, Eunjin Hwang, Youngsoo Kim, Robert E Strecker, Robert W McCarley, Jee Hyun Choi
Homeostatic rebound in rapid eye movement (REM) sleep normally occurs after acute sleep deprivation, but REM sleep rebound settles on a persistently elevated level despite continued accumulation of REM sleep debt during chronic sleep restriction (CSR). Using high-density EEG in mice, we studied how this pattern of global regulation is implemented in cortical regions with different functions and network architectures. We found that across all areas, slow oscillations repeated the behavioral pattern of persistent enhancement during CSR, whereas high-frequency oscillations showed progressive increases...
February 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28193195/assessing-the-burden-of-treatment-emergent-adverse-events-associated-with-atypical-antipsychotic-medications
#8
Pierre-Michel Llorca, Christophe Lançon, Ann Hartry, T Michelle Brown, Dana B DiBenedetti, Siddhesh A Kamat, Clément François
BACKGROUND: Treatment of schizophrenia and major depressive disorder (MDD) with atypical antipsychotics (AAPs) show improved efficacy and reduced side effect burden compared with older antipsychotic medications. However, a risk of treatment-emergent adverse events (TEAEs) remains. TEAEs are hard to quantify and perspectives on the importance of TEAEs differ across patients and between patients and physicians. The current study is a qualitative assessment that investigates TEAEs of AAPs from both patient and physician perspectives to provide better understanding of the occurrence and burden of TEAEs associated with these medications...
February 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28188124/commencing-and-persisting-with-a-web-based-cognitive-behavioral-intervention-for-insomnia-a-qualitative-study-of-treatment-completers
#9
Charles Chan, Stacey West, Nick Glozier
BACKGROUND: Computerized cognitive behavioral therapy for insomnia (CCBT-I) has a growing evidence base as a stand-alone intervention, but it is less clear what factors may limit its acceptability and feasibility when combined with clinical care. OBJECTIVE: The purpose of this study was to explore barriers and facilitators to use of an adjunctive CCBT-I program among depressed patients in a psychiatric clinic by using both quantitative and qualitative approaches...
February 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28187770/malaria-risk-in-young-male-travellers-but-local-transmission-persists-a-case-control-study-in-low-transmission-namibia
#10
Jennifer L Smith, Joyce Auala, Erastus Haindongo, Petrina Uusiku, Roly Gosling, Immo Kleinschmidt, Davis Mumbengegwi, Hugh J W Sturrock
BACKGROUND: A key component of malaria elimination campaigns is the identification and targeting of high risk populations. To characterize high risk populations in north central Namibia, a prospective health facility-based case-control study was conducted from December 2012-July 2014. Cases (n = 107) were all patients presenting to any of the 46 health clinics located in the study districts with a confirmed Plasmodium infection by multi-species rapid diagnostic test (RDT). Population controls (n = 679) for each district were RDT negative individuals residing within a household that was randomly selected from a census listing using a two-stage sampling procedure...
February 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28185122/multidisciplinary-approach-in-the-treatment-of-resistant-hypertension
#11
REVIEW
S A Potthoff, O Vonend
With its high prevalence and the eminent number of undetected or poorly controlled patients, the management of arterial hypertension is still a challenging task. Uncontrolled blood pressure is the major adjustable risk factor for cardiovascular end organ damage for coronary heart disease, heart failure, stroke, and renal disease. Patients with resistant hypertension often need a multidisciplinary approach in order to control their blood pressure sustainably. In cooperation with hypertension specialists, the underlying cause for therapy resistance should be evaluated...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28179566/human-and-rat-gut-microbiome-composition-is-maintained-following-sleep-restriction
#12
Shirley L Zhang, Lei Bai, Namni Goel, Aubrey Bailey, Christopher J Jang, Frederic D Bushman, Peter Meerlo, David F Dinges, Amita Sehgal
Insufficient sleep increasingly characterizes modern society, contributing to a host of serious medical problems. Loss of sleep is associated with metabolic diseases such as obesity and diabetes, cardiovascular disorders, and neurological and cognitive impairments. Shifts in gut microbiome composition have also been associated with the same pathologies; therefore, we hypothesized that sleep restriction may perturb the gut microbiome to contribute to a disease state. In this study, we examined the fecal microbiome by using a cross-species approach in both rat and human studies of sleep restriction...
February 8, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28173767/musculoskeletal-pain-and-co-morbid-insomnia-in-adults-a-population-study-of-the-prevalence-and-impact-on-restricted-social-participation
#13
Shula Baker, John McBeth, Carolyn A Chew-Graham, Ross Wilkie
BACKGROUND: Comorbidity is common in patients consulting in primary care. Musculoskeletal pain and insomnia each increase the risk of the other. Co-occurrence may pose an increased burden on well-being. However, the prevalence and impact of co-existing pain and insomnia in adults living in the community who may present to primary care is unclear. The aim of this study was to report the prevalence of pain and insomnia in adults registered with primary care, and to examine the impact of co-occurrence on social activities...
February 7, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28169885/repetitive-exposure-to-shortened-sleep-leads-to-blunted-sleep-associated-blood-pressure-dipping
#14
Huan Yang, Monika Haack, Shiva Gautam, Hans K Meier-Ewert, Janet M Mullington
BACKGROUND: Blood pressure (BP) dips at night during sleep in healthy individuals but in disturbed sleep, dipping is blunted. However, the impact of chronic insufficient sleep duration, with limited intermittent recovery sleep, on BP dipping is not known. The objective of this study was to examine, in a controlled experimental model, the influence of chronic sleep restriction on BP patterns at night and during the day. METHOD: In a highly controlled 22-day in-hospital protocol, 45 healthy participants (age 32 ± 2 years; BMI 24 ± 1 kg/m; 22 men and 23 women) were randomly assigned to one of two conditions: repeated sleep restriction (4 h of sleep/night from 0300 to 0700 h for three nights followed by recovery sleep of 8 h, repeated four times in succession) or a sleep control group (8 h/night from 2300 to 0700 h)...
February 6, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28164452/sleep-obesity-relation-underlying-mechanisms-and-consequences-for-treatment
#15
REVIEW
M-P St-Onge
Short sleep duration has been associated with obesity in numerous epidemiological studies. However, such association studies cannot establish evidence of causality. Clinical intervention studies, on the other hand, can provide information on a causal effect of sleep duration on markers of weight gain: energy intake and energy expenditure. Herein is an overview of the science related to the impact of sleep restriction, in the context of clinical intervention studies, on energy intake, energy expenditure and body weight...
February 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28156163/post-infarct-sleep-disruption-and-its-relation-to-cardiac-remodeling-in-a-rat-model-of-myocardial-infarction
#16
Marjan Aghajani, Mahdieh Faghihi, Alireza Imani, Mohammad Reza Vaez Mahdavi, Abbas Shakoori, Tayebeh Rastegar, Hoda Parsa, Saman Mehrabi, Fatemeh Moradi, Ehsan Kazemi Moghaddam
Sleep disruption after myocardial infarction (MI) by affecting ubiquitin-proteasome system (UPS) is thought to contribute to myocardial remodeling and progressive worsening of cardiac function. The aim of current study was to test the hypothesis about the increased risk of developing heart failure due to experience of sleep restriction (SR) after MI. Male Wistar rats (n = 40) were randomly assigned to four experimental groups: (1) Sham, (2) MI, (3) MI and SR (MI + SR) (4) Sham and SR (Sham + SR). MI was induced by permanent ligation of left anterior descending coronary artery...
February 3, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28145081/chronic-sleep-restriction-induces-cognitive-deficits-and-cortical-beta-amyloid-deposition-in-mice-via-bace1-antisense-activation
#17
Hong-Yi Zhao, Hui-Juan Wu, Jia-Lin He, Jian-Hua Zhuang, Zhen-Yu Liu, Liu-Qing Huang, Zhong-Xin Zhao
AIMS: To clarify the correlation between chronic sleep restriction (CSR) and sporadic Alzheimer disease (AD), we determined in wild-type mice the impact of CSR, on cognitive performance, beta-amyloid (Aβ) peptides, and its feed-forward regulators regarding AD pathogenesis. METHODS: Sixteen nine-month-old C57BL/6 male mice were equally divided into the CSR and control groups. CSR was achieved by application of a slowly rotating drum for 2 months. The Morris water maze test was used to assess cognitive impairment...
March 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28143597/the-severity-and-associated-factors-of-participation-restriction-among-community-dwelling-frail-older-people-an-application-of-the-international-classification-of-functioning-disability-and-health-who-icf
#18
Justina Yat Wa Liu
BACKGROUND: The International Classification of Functioning, Disability, and Health (WHO-ICF) describes participation restriction as one aspect of disability. Participation restriction refers to health problems that can hinder people's involvement in different life events. It is rational to believe that the prevalence of participation restriction increases among a frail population. However, information about the level of participation restriction among older people, particularly the pre-frail or frail, remains scant...
January 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28130598/-pain-therapy-with-metamizole-after-ambulatory-surgery
#19
E A Lux, E Neugebauer, M Zimmermann
One third of operations are performed on an outpatient basis in Germany, but methods of postoperative pain therapy are less studied. We observed 126 patients with ambulatory and planned surgery in the field of orthopedics and trauma surgery. They were treated with the analgesic metamizole intra- and postoperatively and completed the patients' questionnaire QUIPS on the first postoperative day. In all, 79 patients (61.7%) reported current pain ≥4 on the numerical rating scale (NRS); 84 (66.6%) had restrictions in mobility, 48 (38...
January 27, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28123662/sleep-restriction-may-lead-to-disruption-in-physiological-attention-and-reaction-time
#20
Arbind Kumar Choudhary, Sadawarte Sahebrao Kishanrao, Anup Kumar Dadarao Dhanvijay, Tanwir Alam
Sleepiness is the condition where for some reason fails to go into a sleep state and will have difficulty in remaining awake even while carrying out activities. Sleep restriction occurs when an individual fails to get enough sleep due to high work demands. The mechanism between sleep restriction and underlying brain physiology deficits is not well assumed. The objective of the present study was to investigate the mental attention (P300) and reaction time [visual (VRT) and auditory (ART)] among night watchmen, at subsequent; first (1st) day, fourth (4th) day and seventh (7th) day of restricted sleep period...
July 2016: Sleep Science
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