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https://www.readbyqxmd.com/read/29332862/using-relaxation-techniques-to-improve-sleep-during-naps
#1
Eden Debellemaniere, Danielle Gomez-Merino, Mégane Erblang, Rodolphe Dorey, Michel Genot, Edith Perreaut-Pierre, André Pisani, Laurent Rocco, Fabien Sauvet, Damien Léger, Arnaud Rabat, Mounir Chennaoui
Insufficient sleep is a common occurrence in occupational settings (e.g. doctors, drivers, soldiers). The resulting sleep debt can lead to daytime sleepiness, fatigue, mood disorder, and cognitive deficits as well as altered vascular, immune and inflammatory responses. Short daytime naps have been shown to be effective at counteracting negative outcomes related to sleep debt with positive effects on daytime sleepiness and performance after a normal or restricted night of sleep in laboratory settings. However, the environmental settings in the workplace and the emotional state of workers are generally not conducive to beneficial effects...
January 13, 2018: Industrial Health
https://www.readbyqxmd.com/read/29332677/pilot-study-of-sleep-and-meal-timing-effects-independent-of-sleep-duration-and-food-intake-on-insulin-sensitivity-in-healthy-individuals
#2
Theresa Pizinger, Kyle Kovtun, Arindam RoyChoudhury, Blandine Laferrère, Ari Shechter, Marie-Pierre St-Onge
This pilot study tested the independent and interactive effects of sleep and meal times, under identical sleep duration and feeding conditions, on insulin sensitivity (Si) in overweight adults. Participants underwent a 4-phase randomized crossover inpatient study differing in sleep times: normal (Ns: 0000-0800 hours) or late (Ls: 0330-1130 hours); and in meal times: normal (Nm: 1, 5, 11, and 12.5 hours after awakening) or late (Lm: 4.5, 8.5, 14.5, and 16 hours after awakening). An insulin-modified frequently sampled intravenous glucose tolerance test, at scheduled breakfast time, and a meal tolerance test, at scheduled lunch time, were performed to assess Si after 3 days in each condition...
February 2018: Sleep Health
https://www.readbyqxmd.com/read/29325109/estimating-adolescent-sleep-need-using-dose-response-modelling
#3
Michelle A Short, Nathan Weber, Chelsea Reynolds, Scott Coussens, Mary A Carskadon
Study Objectives: This study will, (a) estimate the nightly sleep need of human adolescents, (b) determine the time course and severity of sleep-related deficits when sleep is reduced below this optimal quantity, and (c) determine whether sleep restriction perturbs the circadian system as well as the sleep homeostat. Methods: Thirty-four adolescents aged 15 to 17 years spent 10 days and 9 nights in the sleep laboratory. Between two baseline nights and two recovery nights with 10-hours' time in bed (TIB) per night, participants experienced either severe sleep restriction (5-hr TIB), moderate sleep restriction (7...
January 6, 2018: Sleep
https://www.readbyqxmd.com/read/29319835/gastrisk-bypass-fyller-50-%C3%A3-r-fetmaoperationen-som-visade-sig-fungera-mot-diabetes
#4
Per Videhult
Mason performed the first gastric bypass (GBP) for obesity in 1967 after having observed substantial weight loss in patients operated for gastric ulcer.  The weight loss after GBP is 30 % and 2/3 of patients with type II diabetes can stop their medication. Half of the patients can stop medication for hypertension or hyperlipidemia, 75% are cured from reflux and obstructive sleep apnea. GBP prolongs survival especially among diabetics. Restriction and malabsorption is of minor importance for weight loss. The mechanisms underlying weight loss and diabetes remissions are endocrine...
January 9, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29313721/altering-adolescents-pre-bedtime-phone-use-to-achieve-better-sleep-health
#5
K Bartel, R Scheeren, M Gradisar
Mobile phone use is often blamed for adolescent sleeping difficulties in the popular and scientific literature, with correlations observed between adolescents' mobile phone use and their bedtime. We aimed to obtain experimental evidence to support these causal claims. A within-subjects experiment (baseline, intervention) was conducted in adolescents' homes, to determine the effect of restricting adolescents' pre-bed mobile phone use on school night sleep habits. Following a baseline week, adolescents were given individualized phone stop times, 1 hour before bed for one school week...
January 9, 2018: Health Communication
https://www.readbyqxmd.com/read/29309411/tungiasis-related-life-quality-impairment-in-children-living-in-rural-kenya
#6
Susanne Wiese, Lynne Elson, Hermann Feldmeier
BACKGROUND: Tungiasis (sand flea disease) is a neglected tropical skin disease caused by female sand fleas (Tunga spp.) embedded in the skin of the host. The disease is common in sub-Saharan Africa and predominantly affects children living in impoverished rural communities. In these settings tungiasis is associated with important morbidity. Whether tungiasis impairs life quality has never been studied. METHODS: The study was performed in 50 children with tungiasis, living in resource-poor communities in coastal Kenya...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29302618/time-restricted-feeding-improves-circadian-dysfunction-as-well-as-motor-symptoms-in-the-q175-mouse-model-of-huntington-s-disease
#7
Huei-Bin Wang, Dawn H Loh, Daniel S Whittaker, Tamara Cutler, David Howland, Christopher S Colwell
Huntington's disease (HD) patients suffer from a progressive neurodegeneration that results in cognitive, psychiatric, cardiovascular, and motor dysfunction. Disturbances in sleep/wake cycles are common among HD patients with reports of delayed sleep onset, frequent bedtime awakenings, and fatigue during the day. The heterozygous Q175 mouse model of HD has been shown to phenocopy many HD core symptoms including circadian dysfunctions. Because circadian dysfunction manifests early in the disease in both patients and mouse models, we sought to determine if early intervention that improve circadian rhythmicity can benefit HD and delay disease progression...
January 2018: ENeuro
https://www.readbyqxmd.com/read/29298300/neonicotinoid-residues-in-uk-honey-despite-european-union-moratorium
#8
Ben A Woodcock, Lucy Ridding, Stephen N Freeman, M Gloria Pereira, Darren Sleep, John Redhead, David Aston, Norman L Carreck, Richard F Shore, James M Bullock, Matthew S Heard, Richard F Pywell
Due to concerns over negative impacts on insect pollinators, the European Union has implemented a moratorium on the use of three neonicotinoid pesticide seed dressings for mass-flowering crops. We assessed the effectiveness of this policy in reducing the exposure risk to honeybees by collecting 130 samples of honey from bee keepers across the UK before (2014: N = 21) and after the moratorium was in effect (2015: N = 109). Neonicotinoids were present in about half of the honey samples taken before the moratorium, and they were present in over a fifth of honey samples following the moratorium...
2018: PloS One
https://www.readbyqxmd.com/read/29290595/the-media-response-to-the-acgme-s-2017-relaxed-resident-duty-hour-restrictions
#9
Zi Zhang, Alan V Krauthamer, Andrew B Rosenkrantz
PURPOSE: In March 2017, the ACGME relaxed resident duty-hour restrictions to allow first-year residents to work 24-hour shifts, affecting the internship experience of incoming radiology residents. The aim of this study was to assess the media response to this duty-hour change, comparing news articles with favorable and unfavorable views. METHODS: Google News was used to identify 36 relevant unique news articles published over a 4-week period after the announcement...
December 28, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29280292/hypopharyngeal-evaluation-in-obstructive-sleep-apnea-with-awake-flexible-laryngoscopy-validation-and-updates-to-cormack-lehane-and-modified-cormack-lehane-scoring-systems
#10
Carlos Torre, Soroush Zaghi, Macario Camacho, Robson Capasso, Stanley Yung-Chuan Liu
OBJECTIVE: To validate the use of Cormack-Lehane and Modified Cormack-Lehane scoring systems to classify patterns of hypopharyngeal airway visualization seen during awake flexible laryngoscopy among patients with obstructive sleep apnea. STUDY DESIGN: Validation study using samples collected from a prospective database. SETTING: University Medical Center. PARTICIPANTS: Data was obtained from a retrospective review of a prospective database of flexible fiberoptic examination recordings in 274 consecutive OSA subjects (Stanford Sleep Medicine/Surgery Clinic)...
December 26, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29273758/the-sleep-eeg-spectrum-is-a-sexually-dimorphic-marker-of-general-intelligence
#11
Péter P Ujma, Boris N Konrad, Ferenc Gombos, Péter Simor, Adrián Pótári, Lisa Genzel, Marcel Pawlowski, Axel Steiger, Róbert Bódizs, Martin Dresler
The shape of the EEG spectrum in sleep relies on genetic and anatomical factors and forms an individual "EEG fingerprint". Spectral components of EEG were shown to be connected to mental ability both in sleep and wakefulness. EEG sleep spindle correlates of intelligence, however, exhibit a sexual dimorphism, with a more pronounced association to intelligence in females than males. In a sample of 151 healthy individuals, we investigated how intelligence is related to spectral components of full-night sleep EEG, while controlling for the effects of age...
December 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29247999/interleukin-1-gene-polymorphism-and-susceptibility-to-disease
#12
REVIEW
Khaled Khazim, Etti Ester Azulay, Batya Kristal, Idan Cohen
The Interleukin 1 (IL-1) family plays a central role in the generation and regulation of inflammatory responses, in both innate and adaptive immunity. Although the IL-1 molecules are traditionally considered to be classical proinflammatory cytokines, their functions are not restricted to inflammation, and they have also been shown to play a key role in a wide range of additional physiological and pathological functions, including learning modulation, sleep, pregnancy, depression, appetite, hematopoiesis, metabolism, and many others...
January 2018: Immunological Reviews
https://www.readbyqxmd.com/read/29246812/sleep-restriction-undermines-cardiovascular-adaptation-during-stress-contingent-on-emotional-stability
#13
Wei Lü, Brian M Hughes, Siobhán Howard, Jack E James
Sleep loss is associated with increased cardiovascular disease, but physiological mechanisms accounting for this relationship are largely unknown. One possible mechanism is that sleep restriction exerts effects on cardiovascular stress responses, and that these effects vary between individuals. Emotional stability (ES) is a personality trait pertinent to sleep restriction and stress responding. However, no study to date has explored how ES and sleep-restriction interactively affect cardiovascular stress responses or processes of adaptation during stress...
December 12, 2017: Biological Psychology
https://www.readbyqxmd.com/read/29246805/substrate-specificity-profiling-of-m32-metallocarboxypeptidases-from-trypanosoma-cruzi-and-trypanosoma-brucei
#14
Alejandra P Frasch, León A Bouvier, Florencia M Oppenheimer, Maria Aparecida Juliano, Luiz Juliano, Adriana K Carmona, Juan José Cazzulo, Gabriela T Niemirowicz
Metallocarboxypeptidases (MCPs) of the M32 family, while broadly distributed among prokaryotic organisms, have so far been only found in a few eukaryotes including trypanosomatids. Among these organisms are human and animal pathogens of medical relevance such as Trypanosoma brucei and Trypanosoma cruzi, the respective causative agents of sleeping sickness and Chagas disease. The M32 MCP orthologues found in these parasites share 72% protein sequence identity. They also present a cytosolic localization, a similar pattern of expression and a marked preference for Arg/Lys residues at P1'...
December 12, 2017: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/29237935/isolated-thyrotropin-elevation-is-associated-with-insufficient-night-sleep-in-night-sleep-restricted-subjects
#15
Yue-Rong Yan, Jia-Qi Li, Ye-Rong Yu
No abstract text is available yet for this article.
December 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29233906/skeletal-muscle-insulin-signaling-and-whole-body-glucose-metabolism-following-acute-sleep-restriction-in-healthy-males
#16
Emma L Sweeney, Stewart Jeromson, D Lee Hamilton, Naomi E Brooks, Ian H Walshe
Sleep restriction is associated with impaired glucose metabolism and insulin resistance, however, the underlying mechanisms leading to this impairment are unknown. This study aimed to assess whether the decrease in insulin sensitivity observed after sleep restriction is accompanied by changes in skeletal muscle PKB activity. Ten healthy young males participated in this randomized crossover study which included two conditions separated by a 3-week washout period. Participants underwent two nights of habitual sleep (CON) and two nights of sleep which was restricted to 50% of habitual sleep duration (SR) in the home environment...
December 2017: Physiological Reports
https://www.readbyqxmd.com/read/29225920/relationship-between-shift-work-and-the-onset-of-rheumatoid-arthritis
#17
Anna Karin Hedström, Torbjörn Åkerstedt, Lars Klareskog, Lars Alfredsson
Background: Environmental factors play a prominent role in rheumatoid arthritis (RA) aetiology. Shift work has previously been associated with increased RA risk in females. The aim of this study was to investigate the potential association, including a dose-response association, between permanent night shift work, rotating shift work and day-oriented shift work and risk of developing anticitrullinated peptide antibodies (ACPA)-positive and ACPA-negative RA. Methods: The present report is based on a population-based, case-control study with incident cases of RA (1951 cases and 2225 controls matched by age, gender and residential area)...
2017: RMD Open
https://www.readbyqxmd.com/read/29204433/adaptive-servoventilation-in-clinical-practice-beyond-serve-hf
#18
Winfried Randerath, Katja Schumann, Marcel Treml, Simon Herkenrath, Alessandra Castrogiovanni, Shahrokh Javaheri, Rami Khayat
Adaptive servoventilation (ASV) has proven effective at suppressing breathing disturbances during sleep, improving quality of life and cardiac surrogate parameters. Since the publication of the SERVE-HF-trial, ASV became restricted. The purpose of this study was to evaluate the clinical relevance of the SERVE-HF inclusion criteria in real life and estimate the portion of patients with these criteria with or without risk factors who are undergoing ASV treatment. We performed a retrospective study of all patients who were treated with ASV in a university-affiliated sleep laboratory...
October 2017: ERJ Open Research
https://www.readbyqxmd.com/read/29187246/comparison-of-bispectral-index%C3%A2-values-during-the-flotation-restricted-environmental-stimulation-technique-and-results-for-stage-i-sleep-a-prospective-pilot-investigation
#19
C Michael Dunham, Jesse V McClain, Amanda Burger
OBJECTIVE: To determine whether Bispectral Index™ values obtained during flotation-restricted environment stimulation technique have a similar profile in a single observation compared to literature-derived results found during sleep and other relaxation-induction interventions. RESULTS: Bispectral Index™ values were as follows: awake-state, 96.6; float session-1, 84.3; float session-2, 82.3; relaxation-induction, 82.8; stage I sleep, 86.0; stage II sleep, 66...
November 29, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29179101/the-cinderella-syndrome-a-narrative-study-of-social-curfews-and-lifestyle-restrictions-in-juvenile-myoclonic-epilepsy
#20
Teresa Leahy, Michael J Hennessy, Timothy J Counihan
Several factors are thought to contribute to inadequate seizure control in patients with juvenile myoclonic epilepsy (JME), including drug resistance, neuropsychiatric comorbidity, and poor lifestyle choices. Recent evidence supports the existence of frontal lobe microstructural deficits and behavioral changes that may contribute to poor seizure control in a minority of patients. Counseling patients on the importance of adequate sleep hygiene and alcohol restriction is an important part of the management strategy for patients with JME...
November 24, 2017: Epilepsy & Behavior: E&B
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