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https://www.readbyqxmd.com/read/28934531/feasibility-and-emotional-impact-of-experimentally-extending-sleep-in-short-sleeping-adolescents
#1
Tori R Van Dyk, Nanhua Zhang, Perry A Catlin, Kaylin Cornist, Shealan McAlister, Catharine Whitacre, Dean W Beebe
Study Objectives: Published experimental sleep manipulation protocols for adolescents have been limited to the summer, limiting causal conclusions about how short sleep affects them on school nights, when they are most likely to restrict their sleep. This study assesses the feasibility and emotional impact of a school-night sleep manipulation protocol to test the effects of lengthening sleep in habitually short-sleeping adolescents. Methods: High school students aged 14-18 years who habitually slept 5-7 hours on school nights participated in a 5-week experimental sleep manipulation protocol...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934530/intraindividual-increase-of-homeostatic-sleep-pressure-across-acute-and-chronic-sleep-loss-a-high-density-eeg-study
#2
Angelina Maric, Caroline Lustenberger, Esther Werth, Christian R Baumann, Rositsa Poryazova, Reto Huber
Study Objectives: To compare intraindividually the effects of acute sleep deprivation (ASD) and chronic sleep restriction (CSR) on the homeostatic increase in slow wave activity (SWA) and to relate it to impairments in basic cognitive functioning, that is, vigilance. Methods: The increase in SWA after ASD (40 hours of wakefulness) and after CSR (seven nights with time in bed restricted to 5 hours per night) relative to baseline sleep was assessed in nine healthy, male participants (age = 18-26 years) by high-density electroencephalography...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934525/short-daytime-naps-briefly-attenuate-objectively-measured-sleepiness-under-chronic-sleep-restriction
#3
Jared M Saletin, Cassie J Hilditch, William C Dement, Mary A Carskadon
Study Objectives: Napping is a useful countermeasure to the negative effects of acute sleep loss on alertness. The efficacy of naps to recover from chronic sleep loss is less well understood. Methods: Following 2 baseline nights (10 hours' time-in-bed), participants were restricted to 7 nights of 5-hour sleep opportunity. Ten adults participated in the No-Nap condition, and a further 9 were assigned to a Nap condition with a daily 45-minute nap opportunity at 1300 h...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28931026/does-physical-activity-buffer-insomnia-due-to-back-and-neck-pain
#4
Iben Axén, Lydia Kwak, Jan Hagberg, Irene Jensen
INTRODUCTION: Musculoskeletal pain is highly prevalent and a burden to society, recurrent and persistent low back pain (LBP) and neck pain (NP) being the most common conditions. They are associated with other poor health outcomes such as sleep problems. Physical activity (PA) prevents LBP and NP, but the direct effect on sleep is unclear. This study explored the effect of pain on insomnia, and examined if adherence to moderate-to-high intensity levels of PA influenced this relationship...
2017: PloS One
https://www.readbyqxmd.com/read/28929462/can-body-temperature-dysregulation-explain-the-co-occurrence-between-overweight-obesity-sleep-impairment-late-night-eating-and-a-sedentary-lifestyle
#5
REVIEW
Rhonda F Brown, Einar B Thorsteinsson, Michael Smithson, C Laird Birmingham, Hessah Aljarallah, Christopher Nolan
PURPOSE: Overweight/obesity, sleep disturbance, night eating, and a sedentary lifestyle are common co-occurring problems. There is a tendency for them to co-occur together more often than they occur alone. In some cases, there is clarity as to the time course and evolution of the phenomena. However, specific mechanism(s) that are proposed to explain a single co-occurrence cannot fully explain the more generalized tendency to develop concurrent symptoms and/or disorders after developing one of the phenomena...
September 19, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28929224/long-working-hours-directly-and-indirectly-via-short-sleep-duration-induce-headache-even-in-healthy-white-collar-men-cross-sectional-and-1-year-follow-up-analyses
#6
Teruo Nagaya, Minoru Hibino, Yasuaki Kondo
OBJECTIVE: Headache in employees may be linked with both overwork and sleep restriction induced by long working hours. Inter-relationships among working hours, sleep duration and headache were investigated. METHODS: Cross-sectional analyses for prevalent headache (n = 35,908) and 1-year follow-up analyses for incident headache (n = 19,788) were conducted in apparently healthy white-collar men aged 25-59 years. Headache (yes/no), working hours and sleep duration were based on self-administered questionnaire...
September 19, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28924681/family-caregivers-to-adults-with-cancer-the-consequences-of-caring
#7
Anna-Leila Williams
A person living with cancer will potentially have some degree of physical, cognitive, and/or psychological impairment, periods of unemployment, financial concerns, social isolation, and existential questions, any or all of which can impact the family and friends who surround them. In our current era of health care, patients with cancer receive invasive diagnostic studies and aggressive treatment as outpatients, and then convalesce at home. As such, cancer family caregivers are de facto partners with the healthcare team...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28922535/power-and-coherence-of-cortical-high-frequency-oscillations-during-wakefulness-and-sleep
#8
Matías Cavelli, Daniel Rojas-Líbano, Natalia Schwarzkopf, Santiago Castro-Zaballa, Joaquín Gonzalez, Alejandra Mondino, Noelia Santana, Luciana Benedetto, Atilio Falconi, Pablo Torterolo
Recently, a novel type of fast cortical oscillatory activity that occurs between 110 and 160 Hz (high-frequency oscillations (HFO)) was described. HFO are modulated by the theta rhythm in hippocampus and neocortex during active wakefulness and REM sleep. Since theta-HFO coupling increases during REM, a role for HFO in memory consolidation has been proposed. However, global properties like the cortex-wide topographic distribution, and the cortico-cortical coherence remain unknown. In the present study, we recorded the electroencephalogram during sleep and wakefulness in the rat, and analyzed the spatial extent of the HFO band power and coherence...
September 18, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28921528/practitioner-review-treatment-of-chronic-insomnia-in-children-and-adolescents-with-neurodevelopmental-disabilities
#9
REVIEW
Oliviero Bruni, Marco Angriman, Fabrizio Calisti, Alessandro Comandini, Giovanna Esposito, Samuele Cortese, Raffaele Ferri
BACKGROUND: Sleep disturbances, in particular insomnia, represent a common problem in children with neurodevelopmental disabilities (NDDs). Currently, there are no approved medications for insomnia in children by the US Food and Drug Administration or European Medicines Agency and therefore they are prescribed off-label. We critically reviewed pediatric literature on drugs as well as nonpharmacological (behavioral) interventions used for sleep disturbances in children with NDDs. METHODS: PubMed, Ovid (including PsycINFO, Ovid MEDLINE(®) , and Embase), and Web of Knowledge databases were searched through February 12, 2017, with no language restrictions...
September 18, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28915069/facilitators-and-barriers-to-positive-airway-pressure-adherence-for-adolescents-a-qualitative-study
#10
Zahra Alebraheem, Alene Toulany, Adele Baker, Jennifer Christian, Indra Narang
RATIONALE: Low adherence to positive airway pressure (PAP) treatment for adolescents with obstructive sleep apnea (OSA) can have long-term cardio-metabolic and developmental impact. OBJECTIVES: To explore the facilitators and barriers to PAP use in adolescents with OSA. METHODS: We conducted a qualitative study using a descriptive thematic analysis approach. A total of 21 interviews were conducted in the clinical setting with adolescents prescribed PAP to treat OSA within the previous 12 months...
September 15, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28912361/impact-of-sleep-restriction-on-local-immune-response-and-skin-barrier-restoration-with-and-without-multi-nutrient-nutrition-intervention
#11
Tracey J Smith, Marques A Wilson, J Philip Karl, Jeb Orr, Carl D Smith, Adam D Cooper, Kristin J Heaton, Andrew J Young, Scott J Montain
Systemic immune function is impaired by sleep restriction. However, the impact of sleep restriction on local immune responses, and to what extent any impairment can be mitigated by nutritional supplementation is unknown. We assessed the effect of 72-h sleep restriction (2-h nightly sleep) on local immune function and skin barrier restoration of an experimental wound, and determined the influence of habitual protein intake (1.5 g·kg(-1)·d(-1)) supplemented with arginine, glutamine, zinc sulfate, vitamin C, vitamin D3 and omega-3 fatty acids compared to lower protein intake (0...
September 14, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28891869/chronic-exposure-to-insufficient-sleep-alters-processes-of-pain-habituation-and-sensitization
#12
Norah S Simpson, Jennifer Scott-Sutherland, Shiva Gautam, Navil Sethna, Monika Haack
Chronic pain conditions are highly co-morbid with insufficient sleep. While the mechanistic relationships between the two are not understood, chronic insufficient sleep may be one pathway through which central pain-modulatory circuits deteriorate, thereby contributing to chronic pain vulnerability over time. To test this hypothesis, an in-laboratory model of three weeks of restricted sleep with limited recovery (five nights of 4-hour sleep/night followed by two nights of 8-hour sleep/night) was compared to three weeks of 8-hour sleep/night (control protocol)...
September 1, 2017: Pain
https://www.readbyqxmd.com/read/28880200/the-endocannabinoid-system-and-autism-spectrum-disorders-insights-from-animal-models
#13
REVIEW
Erica Zamberletti, Marina Gabaglio, Daniela Parolaro
Autism spectrum disorder (ASD) defines a group of neurodevelopmental disorders whose symptoms include impaired communication and social interaction with restricted or repetitive motor movements, frequently associated with general cognitive deficits. Although it is among the most severe chronic childhood disorders in terms of prevalence, morbidity, and impact to the society, no effective treatment for ASD is yet available, possibly because its neurobiological basis is not clearly understood hence specific drugs have not yet been developed...
September 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28862738/doppler-based-fetal-heart-rate-analysis-markers-for-the-detection-of-early-intrauterine-growth-restriction
#14
Lisa Stroux, Christopher W Redman, Antoniya Georgieva, Stephen J Payne, Gari D Clifford
INTRODUCTION: One indicator for fetal risk of mortality is intra-uterine growth restriction (IUGR). Whether markers reflecting the impact of growth restriction on the cardiovascular system, computed from a Doppler-derived heart rate signal, would be suitable in its detection antenatally were studied MATERIAL AND METHODS: We used a cardiotocography archive of 1163 IUGR cases and 1163 healthy controls, matched for gestation and gender. We assessed the discriminative power of short-term variability (STV) and long-term variability (LTV) of the fetal heart rate, computed over episodes of high and low variation aiming to separate growth-restricted fetuses from controls...
September 1, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28861653/behavioral-phenotype-of-asd-preschoolers-with-gastrointestinal-symptoms-or-food-selectivity
#15
Margherita Prosperi, Elisa Santocchi, Giulia Balboni, Antonio Narzisi, Margherita Bozza, Francesca Fulceri, Fabio Apicella, Roberta Igliozzi, Angela Cosenza, Raffaella Tancredi, Sara Calderoni, Filippo Muratori
This study investigated the prevalence and type of gastrointestinal (GI) and food selectivity (FS) symptoms in 163 preschoolers with ASD, and their possible links with core ASD features and emotional/behavioural problems. 40.5% of children with ASD had at least one severe GI symptom or FS. Preschoolers with and without GI symptoms and with and without FS were significantly different on several emotional/behavioural problems and restrictive/repetitive behaviours, whereas they did not differ significantly on performance IQ and autistic severity...
August 31, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28860003/sleep-restriction-induced-energy-methylation-and-lipogenesis-metabolic-switches-in-rat-liver
#16
Arjun Sengupta, Seth D Rhoades, Eun Ji Kim, Soumyashant Nayak, Gregory R Grant, Peter Meerlo, Aalim M Weljie
Sleep curtailment is ubiquitous in modern day society. Sleep debt is associated with maladaptive physiological changes that can lead to cardiometabolic and neuropsychiatric pathologies. Recent literature has shown the effects of sleep restriction (SR) on systemic metabolic profiles in biofluids, implying that tissue-specific metabolomes are impacted by SR. To test this hypothesis, we assessed hepatic metabolic profiles of rats after 5days of SR using UPLC-MS based metabolomics analysis and gene expression analysis...
August 28, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28856094/alterations-in-striato-thalamo-pallidal-intrinsic-functional-connectivity-as-a-prodrome-of-parkinson-s-disease
#17
Eran Dayan, Nina Browner
Although the diagnosis of Parkinson's disease (PD) remains anchored around the cardinal motor symptoms of bradykinesia, rest tremor, rigidity and postural instability, it is becoming increasingly clear that the clinical phase of the disease is preceded by a long period of neurodegeneration, which is not readily evident in terms of motor dysfunction. The neurobiological mechanisms that underpin this prodromal phase of PD remain poorly understood. Based on converging evidence of basal ganglia (BG) dysfunction in early PD, we set out to establish whether the prodromal phase of the disease is characterized by alterations in functional communication within the input and output structures of the BG...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28839322/breast-cancer-in-a-patient-with-kindlers-syndrome
#18
Itrat Mehdi, Bassim Jaffar Al Bahrani, Taha Mohsin Al Lawati, Zahid Al Mandhari, Fatima Ramadhan Al Lawati
Breast Cancer (BC) has associated risk factors and genetic factors like BRCA1, and BRCA2. Many benign and malignant disease processes are found concurrently with BC and believed to be additional risk factors like gall bladder stones (cholelithiasis), hypertension, diabetes mellitus, cerebrovascular lesions, arthritis, spine and spinal cord degenerative lesions, infertility, depression, sleep disturbances, obesity, autoimmune diseases (SLE), and thyroid diseases. There are some malignant disease associations like synchronous or metachronous ovarian, colonic and endometrial tumours with Breast cancer...
August 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28833531/insufficient-sleep-enhanced-risk-seeking-relates-to-low-local-sleep-intensity
#19
Angelina Maric, Eszter Montvai, Esther Werth, Matthias Storz, Janina Leemann, Sebastian Weissengruber, Christian C Ruff, Reto Huber, Rositsa Poryazova, Christian R Baumann
OBJECTIVES: Chronic sleep restriction is highly prevalent in modern society and is in its clinical form, insufficient sleep syndrome, one of the most prevalent diagnoses in clinical sleep laboratories, with substantial negative impact on health and community burden. It reflects every-day sleep loss better than acute sleep deprivation, but its effects and particularly the underlying mechanisms remain largely unknown for a variety of critical cognitive domains, as for example risky decision-making...
August 21, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28829322/success-rate-and-technical-quality-of-home-polysomnography-with-self-applicable-electrode-set-in-subjects-with-possible-sleep-bruxism
#20
Tomi Miettinen, Katja Myllymaa, Susanna Westeren-Punnonen, Jari Ahlberg, Taina Hukkanen, Juha Toyras, Reijo Lappalainen, Esa Mervaala, Kirsi Sipila, Sami Myllymaa
Using sleep laboratory polysomnography (PSG) is restricted for the diagnosis of only the most severe sleep disorders due to its low availability and high cost. Home PSG is more affordable, but applying conventional electroencephalography (EEG) electrodes increases its overall complexity and lowers the availability. Simple, self-administered single-channel EEG monitors on the other hand suffer from poor reliability. In this study, we aimed to quantify the reliability of self-administrated home PSG recordings conducted with a newly designed ambulatory electrode set (AES) that enables multi-channel EEG, electrooculography, electromyography and electrocardiography recordings...
August 18, 2017: IEEE Journal of Biomedical and Health Informatics
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