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https://www.readbyqxmd.com/read/28934531/feasibility-and-emotional-impact-of-experimentally-extending-sleep-in-short-sleeping-adolescents
#1
Tori R Van Dyk, Nanhua Zhang, Perry A Catlin, Kaylin Cornist, Shealan McAlister, Catharine Whitacre, Dean W Beebe
Study Objectives: Published experimental sleep manipulation protocols for adolescents have been limited to the summer, limiting causal conclusions about how short sleep affects them on school nights, when they are most likely to restrict their sleep. This study assesses the feasibility and emotional impact of a school-night sleep manipulation protocol to test the effects of lengthening sleep in habitually short-sleeping adolescents. Methods: High school students aged 14-18 years who habitually slept 5-7 hours on school nights participated in a 5-week experimental sleep manipulation protocol...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28930774/high-levels-of-cerebrospinal-fluid-chemokines-point-to-the-presence-of-neuroinflammation-in-peripheral-neuropathic-pain-a-cross-sectional-study-of-two-cohorts-of-patients-compared-to-healthy-controls
#2
Emmanuel Bäckryd, Anne-Li Lind, Måns Thulin, Anders Larsson, Björn Gerdle, Torsten Gordh
Animal models suggest that chemokines are important mediators in the pathophysiology of neuropathic pain. Indeed, these substances have been called "gliotransmitters", a term that illustrates the close interplay between glial cells and neurons in the context of neuroinflammation and pain. However, evidence in humans is scarce. The aim of the study was to determine a comprehensive cerebrospinal fluid (CSF) inflammatory profile for neuropathic pain patients. Our hypothesis was that we would thereby find indications of a postulated on-going process of central neuroinflammation...
September 18, 2017: Pain
https://www.readbyqxmd.com/read/28930252/qigong-and-fibromyalgia-circa-2017
#3
REVIEW
Jana Sawynok, Mary E Lynch
Qigong is an internal art practice with a long history in China. It is currently characterized as meditative movement (or as movement-based embodied contemplative practice), but is also considered as complementary and alternative exercise or mind-body therapy. There are now six controlled trials and nine other reports on the effects of qigong in fibromyalgia. Outcomes are related to amount of practice so it is important to consider this factor in overview analyses. If one considers the 4 trials (201 subjects) that involve diligent practice (30-45 min daily, 6-8 weeks), there are consistent benefits in pain, sleep, impact, and physical and mental function following the regimen, with benefits maintained at 4-6 months...
June 6, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28922849/medullary-serotonin-neuron-abnormalities-in-an-australian-cohort-of-sudden-infant-death-syndrome
#4
Fiona M Bright, Roger W Byard, Robert Vink, David S Paterson
Serotonin (5-hydroxytryptamine [5-HT]) neurons in the medulla oblongata project extensively to key autonomic and respiratory nuclei in the brainstem and spinal cord regulating critical homeostatic functions. Multiple abnormalities in markers of 5-HT function in the medulla in sudden infant death syndrome (SIDS) have been reported, informing the hypothesis that at least a subset of SIDS cases is caused by deficits in 5-HT function resulting in impaired homeostatic responses to potentially life-threatening events during sleep...
October 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28915274/prevalence-of-mind-and-body-exercises-mbe-in-relation-to-demographics-self-rated-health-and-purchases-of-prescribed-psychotropic-drugs-and-analgesics
#5
Lina Rådmark, Linda L Magnusson Hanson, Eva Bojner Horwitz, Walter Osika
This study aims to identify any differences regarding gender, age, socioeconomic status (SES), self-rated health, perceived stress and the purchase of prescribed drugs among people who practice mind and body exercises (MBE) extensively compared to people who do not. METHODS: The study includes 3,913 men and 4,803 women aged 20-72 who participated in the Swedish Longitudinal Occupational Survey of Health (SLOSH). The respondents were divided into three groups depending on frequency of MBE practice (never/seldom/often)...
2017: PloS One
https://www.readbyqxmd.com/read/28912686/roles-of-microglial-phagocytosis-and-inflammatory-mediators-in-the-pathophysiology-of-sleep-disorders
#6
REVIEW
Agnes Nadjar, Henna-Kaisa M Wigren, Marie-Eve Tremblay
Sleep serves crucial learning and memory functions in both nervous and immune systems. Microglia are brain immune cells that actively maintain health through their crucial physiological roles exerted across the lifespan, including phagocytosis of cellular debris and orchestration of neuroinflammation. The past decade has witnessed an explosive growth of microglial research. Considering the recent developments in the field of microglia and sleep, we examine their possible impact on various pathological conditions associated with a gain, disruption, or loss of sleep in this focused mini-review...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28911339/emerging-treatments-for-the-behavioral-and-psychological-symptoms-of-dementia
#7
Abhinav Anand, Puneet Khurana, Jasneet Chawla, Neha Sharma, Navneet Khurana
Dementia is referred to a loss of memory and decline in other mental abilities at levels critical enough to hinder performance of daily activities. It can be of several types, depending on the underlying pathophysiology. The behavioral and psychological symptoms of dementia (BPSD) are various, but the most clinically significant are depression, apathy, and anxiety. Other BPSD include agitation, aberrant motor behavior, elation, hallucinations, and alterations in sleep and appetite. About 90% of sufferers of dementia are affected by BPSD during the course of the illness...
September 15, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28901656/the-effects-of-seasonal-affective-disorder-and-alcohol-abuse-on-sleep-and-snoring-functions-in-a-population-based-study-in-finland
#8
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
Seasonal affective disorder (SAD) is a recurrent depressive disorder with a seasonal pattern. In addition to some specific symptoms such as sad mood, low energy or carbohydrate craving, this mood disorder is also characterized by the presence of sleeping problems and alcohol disorders. Interestingly, there is a strong link between alcohol use and sleeping deficits. Although previous studies have focused extensively on the sleep patterns in SAD patients and patients with alcohol use disorder (AUD), no research has yet been conducted on subjects with comorbid SAD and AUD...
September 13, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28899524/adherence-to-continuous-positive-airway-pressure-improves-attention-psychomotor-function-and-sleepiness-a-bias-reduction-method-with-further-assessment-of-apples
#9
Tyson H Holmes, Clete A Kushida
OBJECTIVE/BACKGROUND: Variable adherence to prescribed therapies for sleep disorders is commonplace. This study was designed to integrate three available statistical technologies (instrumental variables, residual inclusion, and shrinkage) to allow sleep investigators to employ data on variable adherence in the estimation of the causal effect of treatment as received on clinical outcomes. PATIENTS/METHODS: Using data from the Apnea Positive Pressure Long-term Efficacy Study (APPLES), regression adjustment for observed and unobserved confounders was applied to two primary neurocognitive outcomes, plus two measures of sleepiness...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28895023/israel-rake-retractor-modification-to-improve-exposure-during-oropharyngeal-surgery-on-patients-with-larger-body-habitus
#10
Andrew M Vahabzadeh-Hagh, Eddie Ramirez
PURPOSE: Elective oropharyngeal surgery including tonsillectomy and uvulopalatopharyngoplasty performed for obstructive sleep apnea is increasingly performed on patients of larger body habitus. The use of the Crowe-Davis retractor in such patients may be complicated by a large barrel-chest making it difficult to anchor the retractor to the Mayo stand for suspension limiting oropharyngeal exposure. Here, we present a simple modification using the Israel Retractor to facilitate suspension of the Crowe-Davis mouth gag...
September 12, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28893726/a-web-based-lifestyle-medicine-curriculum-facilitating-education-about-lifestyle-medicine-behavioral-change-and-health-care-outcomes
#11
Elizabeth Pegg Frates, Ryan C Xiao, Deepa Sannidhi, Yasamina McBride, Tracie McCargo, Theodore A Stern
BACKGROUND: Lifestyle medicine is the science and application of healthy lifestyles as interventions for the prevention and treatment of disease, and has gained significant momentum as a specialty in recent years. College is a critical time for maintenance and acquisition of healthy habits. Longer-term, more intensive web-based and in-person lifestyle medicine interventions can have a positive effect. Students who are exposed to components of lifestyle medicine in their education have improvements in their health behaviors...
September 11, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/28891869/chronic-exposure-to-insufficient-sleep-alters-processes-of-pain-habituation-and-sensitization
#12
Norah S Simpson, Jennifer Scott-Sutherland, Shiva Gautam, Navil Sethna, Monika Haack
Chronic pain conditions are highly co-morbid with insufficient sleep. While the mechanistic relationships between the two are not understood, chronic insufficient sleep may be one pathway through which central pain-modulatory circuits deteriorate, thereby contributing to chronic pain vulnerability over time. To test this hypothesis, an in-laboratory model of three weeks of restricted sleep with limited recovery (five nights of 4-hour sleep/night followed by two nights of 8-hour sleep/night) was compared to three weeks of 8-hour sleep/night (control protocol)...
September 1, 2017: Pain
https://www.readbyqxmd.com/read/28873072/amplitude-integrated-eeg-and-brain-sparing-in-preterm-small-for-gestational-age-infants
#13
Isabel Benavente-Fernández, Simón P Lubián-López, Pamela Zafra-Rodríguez, Almudena Alonso-Ojembarrena, Antonio Segado-Arenas, Alfonso M Lechuga-Sancho
PURPOSE: Preterm small-for-gestational-age (SGA) infants are at risk for a high mortality rate and impaired cognitive development. Only a few studies have focused on amplitude-integrated EEG (aEEG) in preterm SGA infants. They have been shown to have a slower rate of brain maturation, but these findings have not consistently been related to neurodevelopmental outcomes. The aim of our study was to evaluate early aEEG monitoring in SGA compared with adequate-for-gestational-age preterms...
September 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28859722/validation-of-a-new-system-using-tracheal-body-sound-and-movement-data-for-automated-apnea-hypopnea-index-estimation
#14
Christoph Kalkbrenner, Manuel Eichenlaub, Stefan Rüdiger, Cornelia Kropf-Sanchen, Rainer Brucher, Wolfgang Rottbauer
STUDY OBJECTIVES: The current gold standard for assessment of obstructive sleep apnea is the in-laboratory polysomnography. This approach has high costs and inconveniences the patient, whereas alternative ambulatory systems are limited by reduced diagnostic abilities (type 4 monitors, 1 or 2 channels) or extensive setup (type 3 monitors, at least 4 channels). The current study therefore aims to validate a simplified automated type 4 monitoring system using tracheal body sound and movement data...
August 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28853427/ear-nose-and-throat-ent-aspects-of-obstructive-sleep-apnea-syndrome-osas-diagnosis-and-therapy
#15
Desiderio Passali, Maria Carla Spinosi, Francesco Maria Passali
This article analyzes the role played by the ear, nose and throat (ENT) specialist in the diagnosis and treatment of the Obstructive Sleep Apnea Syndrome (OSAS). DIAGNOSIS: The instrumental methods of investigation of otolaryngology expertise are fiberoptic rhinolaryngoscopy and sleep endoscopy. To better define and treat OSAS it is essential to define location, extension and degree of obstruction. The major limitation of rhinolaryngoscopy is that it is conducted while the patient is awake...
August 28, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/28853425/obstructive-sleep-apnea-syndrome-osas-and-cardiovascular-system
#16
Carolina Lombardi, Eleonora Tobaldini, Nicola Montano, Anna Losurdo, Gianfranco Parati
There is increasing evidence of a relationship between Obstructive Sleep Apnea (OSA) and cardiovascular diseases. The strong association between OSA and arterial hypertension, in particular in patients with resistant hypertension and/or a non-dipping profile, has been extensively reported. The relationship between OSA and high blood pressure (BP) has been found independent from a number of confounders, but several factors may affect this relationship, including age and sex. It is thus important to better assess pathophysiologic and clinical interactions between OSA and arterial hypertension, also aimed at optimizing treatment approaches in OSA and hypertensive patients with co-morbidities...
August 28, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/28840935/effects-of-physical-limitations-on-daily-activities-among-adults-with-mental-health-disorders-opportunities-for-nursing-and-occupational-therapy-interventions
#17
Jennifer Gardner, Margaret Swarbrick, Ariane Ackerman, Theodora Church, Vanessa Rios, Laura Valente, John Rutledge
Individuals living with mental health disorders served by the public mental health system often face comorbid medical conditions that affect their quality of life and lifespan. The effect of physical limitations on the engagement in daily activities among individuals living with mental health disorders has not been extensively researched. Adults attending community wellness centers (N = 53) in a northeastern United State were included in a descriptive study exploring the impact of physical limitations on daily activities...
August 24, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28827214/mobile-mindfulness-intervention-on-an-acute-psychiatric-unit-feasibility-and-acceptability-study
#18
Lisa A Mistler, Dror Ben-Zeev, Elizabeth Carpenter-Song, Mary F Brunette, Matthew J Friedman
BACKGROUND: Aggression and violence on acute psychiatric inpatient units is extensive and leads to negative sequelae for staff and patients. With increasingly acute inpatient milieus due to shorter lengths of stay, inpatient staff is limited in training and time to be able to provide treatments. Mobile technology provides a new platform for offering treatment on such units, but it has not been tested for feasibility or usability in this particular setting. OBJECTIVE: The aim of this study was to examine the feasibility, usability, and acceptability of a brief mindfulness meditation mobile phone app intended to reduce anger and aggression in acute psychiatric inpatients with schizophrenia, schizoaffective disorder, or bipolar disorder, and a history of violence...
August 21, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28820755/sleep-complications-following-traumatic-brain-injury
#19
Natalie A Grima, Jennie L Ponsford, Matthew P Pase
PURPOSE OF REVIEW: Recent research has provided extensive characterization as to the frequency and nature of sleep disturbances following traumatic brain injury (TBI). This review summarizes the current state of knowledge and proposes future directions for research. RECENT FINDINGS: Complaints of sleep disturbance are common following TBI, and objective assessments of sleep largely corroborate these complaints. Sleep is often disturbed in the acute phase postinjury and can persist for decades, with the prevalence of sleep disorders higher in patients with TBI as compared with the general population...
August 17, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28820743/sleep-apnea-a-review-of-diagnostic-sensors-algorithms-and-therapies
#20
Mehdi Shokoueinejad, Chris Fernandez, Emily Carroll, Fa Wang, Jake Levin, Sam Rusk, Nick Glattard, Ashley Mulchrone, Xuan Zhang, Ailiang Xie, Mihaela Teodorescu, Jerome Dempsey, John Webster
While public awareness of sleep related disorders is growing, sleep apnea syndrome (SAS) remains a public health and economic challenge. Over the last two decades, extensive controlled epidemiologic research has clarified the incidence, risk factors including the obesity epidemic, and global prevalence of obstructive sleep apnea (OSA), as well as establishing a growing body of literature linking OSA with cardiovascular morbidity, mortality, metabolic dysregulation, and neurocognitive impairment. The US Institute of Medicine Committee on Sleep Medicine estimates that 50-70 million US adults have sleep or wakefulness disorders...
August 18, 2017: Physiological Measurement
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