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Mark Drew Crosland Guimarães, Carl Kendall, Laio Magno, Gustavo Machado Rocha, Daniela Riva Knauth, Andrea Fachel Leal, Ines Dourado, Maria Amélia Veras, Ana Maria de Brito, Ligia Regina Franco Sansigolo Kerr
INTRODUCTION: Periodic monitoring of sociobehavior characteristics at a national level is an essential component of understanding the dynamics the human immunodeficiency virus (HIV) epidemic worldwide, including Brazil. METHODS: This paper compares descriptive sociobehavior characteristics in 2 national cross-sectional HIV biological behavioral surveillance surveys (BBSS) conducted in 2009 and 2016 among men who have sex with men (MSM) in Brazil. Respondent driven sampling (RDS) was used for recruitment in both years...
May 2018: Medicine (Baltimore)
Andrew Miller, Narelle Eather, Mitch Duncan, David Revalds Lubans
This study investigated if object control relates to children's game play competence, and examined these competencies as correlates of physical activity and cardiorespiratory fitness. Game play (Game Performance Assessment Instrument), object control (The Test Gross Motor Development-3), moderate-to-vigorous physical activity (Accelerometry), and cardiorespiratory fitness (20-metre shuttle) assessments were completed for 107 children (57% Female, 43% Male) aged 9-12 years (M 10.53, SD 0.65). Two-level regression of object control on game play competence, and object control and game play competence on physical activity and cardiorespiratory fitness assessed associations...
June 18, 2018: Journal of Sports Sciences
Luca Gabrielli, Daniele Rosa-Gastaldo, Marie-Virginie Salvia, Sara Springhetti, Federico Rastrelli, Fabrizio Mancin
Properly designed monolayer-protected nanoparticles (2 nm core diameter) can be used as nanoreceptors for selective detection and identification of phenethylamine derivatives (designer drugs) in water. The molecular recognition mechanism is driven by the combination of electrostatic and hydrophobic interactions within the coating monolayer. Each nanoparticle can bind up to 30-40 analyte molecules. The affinity constants range from 105 to 106 M-1 and are modulated by the hydrophobicity of the aromatic moiety in the substrate...
June 7, 2018: Chemical Science
P Mason McClatchey, Nicholas A Mignemi, Zhengang Xu, Ian M Williams, Jane E B Reusch, Owen P McGuinness, David H Wasserman
OBJECTIVE: Changes in microvascular perfusion have been reported in many diseases, yet the functional significance of altered perfusion is often difficult to determine. This is partly because commonly used techniques for perfusion measurement often rely on either indirect or by-hand approaches. METHODS: We developed and validated a fully automated software technique to measure microvascular perfusion in videos acquired by fluorescence microscopy in the mouse gastrocnemius...
June 16, 2018: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
N Morchiladze, B Tkeshelashvili, T Gagua, D Gagua
The isolated hypothyroxinemia of pregnancy (IHP) has gained specific attention in the specialized literature during the recent years as the possible factor impeding the intellectual development of fetus and increasing the risk of complications related with pregnancy, delivery and perinatal period. Aim of the study was to define the importance of isolated hypothyroxinemia in the development of obstetric and somatic pathologies in outpatient population of pregnant females. The study of prospective design was performed at the base of "David Gagua Clinic" Ltd...
May 2018: Georgian Medical News
Kenneth L Seldeen, Manhui Pang, Merced M Leiker, Jonathan E Bard, Maria Rodríguez-Gonzalez, Mireya Hernandez, Zachary Sheridan, Norma Nowak, Bruce R Troen
Vitamin D insufficiency (serum 25-OH vitamin D < 30 ng/ml) affects 70-80% of the general population, yet the long-term impacts on physical performance and the progression of sarcopenia are poorly understood. We therefore followed 6-month-old male C57BL/6J mice ( n =6) consuming either sufficient (STD, 1000 IU) or insufficient (LOW, 125 IU) vitamin D3/kg chow for 12 months (equivalent to 20-30 human years). LOW supplemented mice exhibited a rapid decline of serum 25-OH vitamin D levels by two weeks that remained between 11-15 ng/mL for all time points thereafter...
June 14, 2018: Aging
Hao Liang, Lan Wu, Yingchen Li, Yidi Zeng, Zhixi Hu, Xinchun Li, Xiang Sun, Qiuyan Zhang, Xiaoqing Zhou
BACKGROUND: Prior studies have proposed several electrocardiogram (ECG) criteria in limb leads for identifying the culprit coronary artery (CCA) in patients with acute inferior wall myocardial infarction (IWMI). The aim of our study was to conduct an evidence-based evaluation and test accuracy comparison of these criteria. METHODS: We searched the PubMed, Embase, and Ovid. Eligible studies to assess the diagnostic performance of ECG criteria predicting CCA in IWMI were reviewed for inclusion...
June 2018: Medicine (Baltimore)
Jata S Misra, Anand N Srivastava, Hem P Gupta
OBJECTIVE: Cytological screening was carried out in rural women of Lucknow West, India, through a camp approach to detect cervical cancer in its preinvasive phase and to see whether the primitive living conditions in the villages have any effect on the incidence of precancer and carcinoma of the cervix and the associated predisposing factors of cervical carcinogenesis. STUDY DESIGN: During a span of 4 years (May 2013 to March 2017), a total of 135 camps were organized under the auspice of Era's Lucknow Medical College and Hospital (Lucknow, India)...
June 13, 2018: Acta Cytologica
Jana Taron, Jakob Weiss, Mike Notohamiprodjo, Thomas Kuestner, Fabian Bamberg, Elisabeth Weiland, Bernd Kuehn, Petros Martirosian
OBJECTIVES: Magnetic resonance cholangiopancreatography (MRCP) is an established technique in routine magnetic resonance examination. By applying the compressed sensing (CS) acceleration technique to conventional MRCP sequences, scan time can be markedly reduced. With promising results at 3 T, there is a necessity to evaluate the performance at 1.5 T due to wide scanner availabilities. Aim of this study is to test the feasibility of accelerated 3-dimensional (3D) MRCP with extended sampling perfection with application-optimized contrasts using different flip angle evolution (SPACE) using CS in navigator triggering and in a single breath-hold in a clinical setting at 1...
June 8, 2018: Investigative Radiology
Dong Keon Lee, Yong Sung Cha, Oh Hyun Kim, Kyoung Chul Cha, Kang Hyun Lee, Sung Oh Hwang, Hyun Kim, Young Hwan Lee, Minjung Kathy Chae
BACKGROUND: An automatic simultaneous sternothoracic cardiopulmonary resuscitation (SST-CPR) device is an apparatus that performs CPR by providing simultaneous cyclic compressions of the thorax with a thoracic strap and compression of the sternum with a piston. OBJECTIVE: This study was conducted to compare the hemodynamic effects of CPR with an automatic SST-CPR device to those with standard CPR (STD-CPR) in cardiac arrest patients. METHODS: A randomized trial was performed on victims of out-of-hospital cardiac arrest resistant to initial 20 min of CPR after emergency department (ED) arrival...
June 6, 2018: Journal of Emergency Medicine
Cydnee Ng, Rana Najjar, Natalie DiPietro Mager, Sally Rafie
OBJECTIVES: The primary objective was to assess pharmacist and student pharmacist current involvement and interest in providing preconception care services. Secondary objectives were to assess comfort in providing these services to various subpopulations in addition to training and resource needs. METHODS: A cross-sectional online survey was conducted in the United States and its territories from August 26 to October 14, 2016. Pharmacists and student pharmacists were recruited via a Facebook advertisement to participate in a self-administered survey assessing experiences, interest, and comfort in providing preconception care services in addition to training and resource needs...
June 5, 2018: Journal of the American Pharmacists Association: JAPhA
Jeffrey Walden, Raleigh Rumley
Our patient had previously been treated for syphilis. But when his symptoms persisted, further testing revealed that he was being treated for the wrong STD.
June 2018: Journal of Family Practice
Keren Ladin, Joanna Emerson, Kelsey Berry, Zeeshan Butt, Elisa J Gordon, Norman Daniels, Tara A Lavelle, Douglas W Hanto
Social support is used to determine transplant eligibility despite lack of an evidence-base and vague regulatory guidance. It is unknown how many patients are disqualified from transplantation due to inadequate support, and whether providers feel confident using these subjective criteria to determine eligibility. Transplant providers (n=551) from 202 centers estimated that, on average, 9.6% (std dev 9.4) of patients evaluated in the prior year were excluded due to inadequate support. This varied significantly by UNOS region (7...
June 7, 2018: American Journal of Transplantation
Sultan H Al-Rashidi, Adel A Albahouth, Waleed A Althwini, Abdullah A Alsohibani, Abdulmejeed A Alnughaymishi, Abdulamlaik A Alsaeed, Fahad H Al-Rashidi, Salem Almatrafi
OBJECTIVE: To study the prevalence of various errors of refraction among the medical students studying at the college of medicine, Qassim University, Saudi Arabia. METHODS: This is a cross-sectional descriptive study conducted at Qassim University clinics over a period of two months. The study population comprised 162 male and female students from different academic years. The students were selected randomly so that around 35-40 students were taken from each academic class...
May 20, 2018: Open Access Macedonian Journal of Medical Sciences
Eleanor E Friedman, Hazel D Dean, Wayne A Duffus
OBJECTIVES: Social determinants of health (SDHs) are the complex, structural, and societal factors that are responsible for most health inequities. Since 2003, the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) has researched how SDHs place communities at risk for communicable diseases and poor adolescent health. We described the frequency and types of SDHs discussed in articles authored by NCHHSTP. METHODS: We used the MEDLINE/PubMed search engine to systematically review the frequency and type of SDHs that appeared in peer-reviewed publications available in PubMed from January 1, 2009, through December 31, 2014, with a NCHHSTP affiliation...
January 1, 2018: Public Health Reports
Jun-Chau Chien, Ali Ameri, Erh-Chia Yeh, Alison N Killilea, Mekhail Anwar, Ali M Niknejad
This work presents a microfluidics-integrated label-free flow cytometry-on-a-CMOS platform for the characterization of the cytoplasm dielectric properties at microwave frequencies. Compared with MHz impedance cytometers, operating at GHz frequencies offers direct intracellular permittivity probing due to electric fields penetrating through the cellular membrane. To overcome the detection challenges at high frequencies, the spectrometer employs on-chip oscillator-based sensors, which embeds simultaneous frequency generation, electrode excitation, and signal detection capabilities...
June 6, 2018: Lab on a Chip
Matteo Maspero, Peter R Seevinck, Nicole J W Willems, Gonda G Sikkes, Geja J de Kogel, Hans C J de Boer, Jochem R N van der Voort van Zyp, Cornelis A T van den Berg
BACKGROUND: The use of intraprostatic gold fiducial markers (FMs) ensures highly accurate and precise image-guided radiation therapy for patients diagnosed with prostate cancer thanks to the ease of localising FMs on photon-based imaging, like Computed Tomography (CT) images. Recently, Magnetic Resonance (MR)-only radiotherapy has been proposed to simplify the workflow and reduce possible systematic uncertainties. A critical, determining factor in the accuracy of such an MR-only simulation will be accurate FM localisation using solely MR images...
June 5, 2018: Radiation Oncology
Sean A Buono, Ricardo Basurto-Davila, Hilary A Godwin, Nicole M Green
BACKGROUND: More laboratories are screening for syphilis with automated treponemal immunoassays. We compared direct costs and downstream consequences when a local public health laboratory switches from a traditional algorithm (Nontreponemal screening) to a reverse algorithm (Treponemal screening). METHODS: We created a decision analysis model based on laboratory and surveillance data to estimate the cost-effectiveness of a reverse syphilis-screening algorithm from the perspectives of the Los Angeles County Public Health Laboratory (PHL) and the Los Angeles County Department of Public Health (laboratory + STD Program costs) in 2015 US Dollars...
June 4, 2018: Sexually Transmitted Diseases
Giovanni Corsetti, Evasio Pasini, Claudia Romano, Riccardo Calvani, Anna Picca, Emanuele Marzetti, Vincenzo Flati, Francesco S Dioguardi
Objective: Inadequate protein intake can impair protein balance thus leading to skeletal muscle atrophy, impaired body growth, and functional decline. Foods provide both non-essential (NEAAs) and essential amino acids (EAAs) that may convey different metabolic stimuli to specific organs and tissues. In this study, we sought to evaluate the impact of six diets, with various EAA/NEAA blends, on body composition and the risk of developing tissue wasting in late middle-aged male mice. Methods: Six groups of late middle-aged male mice were fed for 35 days with iso-nutrients, iso-caloric, and iso-nitrogenous special diets containing different EAA/NEAA ratios ranging from 100/0% to 0/100%...
2018: Frontiers in Medicine
Ho Han, Jongil Lim, Richard Viskochil, Elroy J Aguiar, Catrine Tudor-Locke, Stuart R Chipkin
Physical inactivity has been linked to rates of obesity, diabetes and heart disease through insulin resistance and other mechanisms. While sedentary workplace environments have unintentionally contributed to the risk for chronic diseases, innovations in the workplace environment could potentially rectify this public and occupational health problem. PURPOSE: To evaluate the effects of light intensity physical activity using a pedal desk (PD) compared to a standard desk (STD) in a pilot study on postprandial metabolic responses and work skills...
June 1, 2018: Medicine and Science in Sports and Exercise
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