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https://www.readbyqxmd.com/read/28109271/influence-of-surgical-approach-on-heterotopic-ossification-after-total-hip-arthroplasty-is-minimal-invasive-better-a-case-control-study
#1
Maya Hürlimann, Filippo-Franco Schiapparelli, Niccolo Rotigliano, Enrique Testa, Felix Amsler, Michael T Hirschmann
BACKGROUND: Heterotopic ossification (HO) is a well-known complication after total hip arthroplasty (THA). Recently, the trend is to operate THA minimally invasive being less traumatic than standard approaches and promising a faster return to activity. The purpose of the study was to investigate if minimal invasive surgery (MIS), leads also to less HO after THA. METHODS: This retrospective study included 134 consecutive patients undergoing THA. In 42 (31.3%) patients a standard modified anterolateral (STD-Watson-Jones), in 28 (20...
January 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28108699/an-evaluation-study-of-the-becton-dickinson-probetec-qx-bdqx-trichomonas-vaginalis-trichomoniasis-molecular-diagnostic-test-in-two-large-urban-std-services
#2
Craig Tipple, Michael Rayment, Sundhiya Mandalia, Lisa Walton, Sinead O'Neill, John Murray, Alan O'Riordan, Monica Rebec, Laura Harrington, Rachael Jones, Dawn Wilkinson
OBJECTIVES: The BASHH guidelines recommend molecular tests to aid diagnosis of Trichomonas vaginalis (TV) infection; however many clinics continue to use relatively insensitive techniques (pH, wet-prep microscopy (WPM) and culture). Our objectives were to establish a laboratory pathway for TV testing with the Becton-Dickinson Qx (BDQx) molecular assay, to determine TV prevalence and to identify variables associated with TV detection. METHODS: A prospective study of 901 women attending two urban sexual health services for STI testing was conducted...
January 20, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28107896/cortisol-levels-in-hair-are-altered-in-irritable-bowel-syndrome-a-case-control-study-in-primary-care
#3
A-K Norlin, S Walter, E Theodorsson, V Tegelstrom, E Grodzinsky, M P Jones, Å Faresjö
OBJECTIVE: Stress is an important component in the pathophysiology of irritable bowel syndrome (IBS). Long term Hypothalamus Pituitary Adrenal (HPA)-axis activity can be studied by measuring hair cortisol concentrations (HCC). Some previous studies have indicated a dysregulated HPA-axis in IBS patients, but cortisol levels in hair have not yet been studied. We investigated whether HCC and self-reported stress differentiate IBS patients from controls. METHODS: In a cross-sectional study within 10 Swedish Primary Health Care Centers we compared patients in working age with active IBS to patients without GI complaints...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28105260/shear-wave-elastography-in-hepatitis-c-patients-before-and-after-antiviral-therapy
#4
Toshikuni Suda, Osamu Okawa, Rion Masaoka, Yoshinori Gyotoku, Naohiko Tokutomi, Yasumi Katayama, Masaya Tamano
AIM: To investigate shear wave (SW) propagation velocity in patients with untreated hepatitis C and patients with sustained virological response (SVR). METHODS: A total of 136 hepatitis C patients [85 patients who had not received antiviral therapy (naïve group) and 51 patients who had received antiviral therapy and subsequently achieved SVR of at least 24 wk (SVR group)] and 58 healthy volunteers and outpatients without liver disease (control group) underwent evaluation of liver stiffness by SW elastography (SWE)...
January 8, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28103480/adrenergic-gate-release-for-spike-timing-dependent-synaptic-potentiation
#5
Yanling Liu, Lei Cui, Martin K Schwarz, Yan Dong, Oliver M Schlüter
Spike timing-dependent synaptic plasticity (STDP) serves as a key cellular correlate of associative learning, which is facilitated by elevated attentional and emotional states involving activation of adrenergic signaling. At cellular levels, adrenergic signaling increases dendrite excitability, but the underlying mechanisms remain elusive. Here we show that activation of β2-adrenoceptors promoted STD long-term synaptic potentiation at mouse hippocampal excitatory synapses by inactivating dendritic Kv1.1-containing potassium channels, which increased dendrite excitability and facilitated dendritic propagation of postsynaptic depolarization, potentially improving coincidental activation of pre- and postsynaptic terminals...
January 18, 2017: Neuron
https://www.readbyqxmd.com/read/28100187/prevalence-of-hiv-and-syphilis-co-infection-and-associated-factors-among-non-commercial-men-who-have-sex-with-men-attending-a-sexually-transmitted-disease-clinic-in-shenzhen-china
#6
Wenjie Dai, Zhenzhou Luo, Ruiwei Xu, Guanglu Zhao, Dan Tu, Lin Yang, Feng Wang, Yumao Cai, Lina Lan, Fuchang Hong, Tubao Yang, Tiejian Feng
BACKGROUND: Although HIV and syphilis co-infection has been frequently observed in men who have sex with men (MSM), only few studies have focused on it. Different subgroups of MSM might exhibit heterogeneous HIV and syphilis risk profiles, indicating that interventions for HIV and HIV-related co-infections may vary with different subgroups of MSM. However, no previous study has investigated HIV and syphilis co-infection among non-commercial MSM (ncMSM) attending a sexually transmitted disease (STD) clinic...
January 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28097616/operationalizing-the-measurement-of-seroadaptive-behaviors-a-comparison-of-reported-sexual-behaviors-and-purposely-adopted-behaviors-among-men-who-have-sex-with-men-msm-in-seattle
#7
Christine M Khosropour, Julia C Dombrowski, James P Hughes, Lisa E Manhart, Jane M Simoni, Matthew R Golden
Seroadaptive behaviors are traditionally defined by self-reported sexual behavior history, regardless of whether they reflect purposely-adopted risk-mitigation strategies. Among MSM attending an STD clinic in Seattle, Washington 2013-2015 (N = 3751 visits), we used two seroadaptive behavior measures: (1) sexual behavior history reported via clinical computer-assisted self-interview (CASI) (behavioral definition); (2) purposely-adopted risk-reduction behaviors reported via research CASI (purposely-adopted definition)...
January 17, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28095879/treatment-seeking-behaviour-and-barriers-to-service-access-for-sexually-transmitted-diseases-among-men-who-have-sex-with-men-in-china-a-multicentre-cross-sectional-survey
#8
Jun-Jie Xu, Yan-Qiu Yu, Qing-Hai Hu, Hong-Jing Yan, Zhe Wang, Lin Lu, Ming-Hua Zhuang, Xi Chen, Ji-Hua Fu, Wei-Ming Tang, Wen-Qing Geng, Yong-Jun Jiang, Hong Shang
BACKGROUND: Delayed or inappropriate treatment for sexually transmitted diseases (STDs) increases the risk of HIV acquisition and may cause other harmful outcomes. However, studies on STD treatment-seeking behaviour and correlated factors in men who have sex with men (MSM) are scarce. This information is crucial for the promotion of STD treatment-seeking behaviour and reduction of HIV transmission among Chinese MSM. METHODS: During 2012-2013, a multicentre cross-sectional study was conducted in 7 Chinese cities...
January 18, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28088482/combined-spatiotemporal-ica-stica-for-continuous-and-dynamic-lag-structure-analysis-of-mreg-data
#9
Ville Raatikainen, Niko Huotari, Vesa Korhonen, Aleksi Rasila, Janne Kananen, Lauri Raitamaa, Tuija Keinänen, Jussi Kantola, Osmo Tervonen, Vesa Kiviniemi
This study investigated lag structure in the resting-state fMRI by applying a novel independent component (ICA) method to magnetic resonance encephalography (MREG) data. Briefly, the spatial ICA (sICA) was used for defining the frontal and back nodes of the default mode network (DMN), and the temporal ICA (tICA), which is enabled by the high temporal resolution of MREG (TR=100ms), was used to separate both neuronal and physiological components of these two spatial map regions. Subsequently, lag structure was investigated between the frontal (DMNvmpf) and posterior (DMNpcc) DMN nodes using both conventional method with all-time points and a sliding-window approach...
January 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28088411/standardization-of-milk-infrared-spectra-for-the-retroactive-application-of-calibration-models
#10
V Bonfatti, A Fleming, A Koeck, F Miglior
The objective of this study was to standardize the infrared spectra obtained over time and across 2 milk laboratories of Canada to create a uniform historical database and allow (1) the retroactive application of calibration models for prediction of fine milk composition; and (2) the direct use of spectral information for the development of indicators of animal health and efficiency. Spectral variation across laboratories and over time was inspected by principal components analysis (PCA). Shifts in the PCA scores were detected over time, leading to the definition of different subsets of spectra having homogeneous infrared signal...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28079763/the-comparison-of-etomidate-and-propofol-anesthesia-in-patients-undergoing-gastrointestinal-endoscopy-a-systematic-review-and-meta-analysis
#11
Limin Ye, Xiangyang Xiao, Liyi Zhu
INTRODUCTION: Etomidate and propofol played an important role in the sedation of patients undergoing gastrointestinal endoscopy. We conducted a systematic review and meta-analysis to compare their efficacy and safety. MATERIALS AND METHODS: PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials assessing the effect of etomidate versus propofol for the anesthesia of patients undergoing gastrointestinal endoscopy were included...
January 10, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28078345/comparison-between-the-optical-properties-of-aerosols-in-the-fine-and-coarse-fractions-over-valladolid-spain
#12
S Mogo, J F López, V E Cachorro, A de Frutos, R Zocca, A Barroso, D Mateos, E Conceição
Continuous measurements of the optical properties of aerosol particles have been made at Valladolid, Spain, covering the period from June 2011 to July 2012. The measurements were made at two size cuts: sub-10 μm and sub-1 μm (PM10 and PM1). The data measured were the scattering and backscattering coefficients, σs and σbs, obtained from an integrating nephelometer, and the absorption coefficient, σa, obtained from a particle soot absorption photometer. Spectrally resolved data were obtained from both instruments at 3 wavelengths (blue/green/red) at low relative humidity (RH < 40%)...
January 12, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28077280/engineering-out-the-noise
#13
Kurt Yankaskas, Raymond Fischer, Jesse Spence, Jeff Komrower
The US Navy, through an Office of Naval Research (ONR) lead effort on Noise Induced Hearing Loss (NIHL), is investigating methods and techniques to mitigate hearing loss for the crews and warfighters. Hearing protection is a viable and increasingly popular method of reducing hearing exposure for many ship crewmembers; however, it has limitations on comfort and low frequency effectiveness. Furthermore, Personal Hearing Protection (PHP) is often used improperly. Proper vessel planning, programmatic changes and advances in noise control engineering can also have significant impacts by inherently reducing noise exposure through ship design and use of noise control treatments...
January 7, 2017: Hearing Research
https://www.readbyqxmd.com/read/28060999/statistical-image-domain-multi-material-decomposition-for-dual-energy-ct
#14
Yi Xue, Ruoshui Ruan, Xiuhua Hu, Yu Kuang, Jing Wang, Yong Long, Tianye Niu
PURPOSE: Dual-energy CT (DECT) enhances tissue characterization because of its basis material decomposition capability. In addition to conventional two-material decomposition from DECT measurements, multi-material decomposition (MMD) is required in many clinical applications. To solve the ill-posed problem of reconstructing multiple-material images from dual-energy measurements, additional constraints are incorporated into the formulation, including volume and mass conservation and the assumptions that at most three materials in each pixel and various material types among pixels...
January 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28058659/three-minute-spect-ct-is-sufficient-for-the-assessment-of-bone-metastasis-as-add-on-to-planar-bone-scintigraphy-prospective-head-to-head-comparison-to-11-min-spect-ct
#15
Helle D Zacho, José A Biurrun Manresa, Ramune Aleksyniene, June A Ejlersen, Joan Fledelius, Henrik Bertelsen, Lars J Petersen
BACKGROUND: The aim of this study is to assess whether ultra-fast acquisition SPECT/CT (UF-SPECT/CT) can replace standard SPECT/CT (std-SPECT/CT) as "add-on" to whole-body bone scintigraphy (WB-BS) for the investigation of bone metastases. Consecutive cancer patients referred for WB-BS who underwent SPECT/CT in addition to WB-BS were included. Std-SPECT, UF-SPECT, and low-dose CT were performed (std-SPECT: matrix 128 × 128, zoom factor 1, 20 s/view, 32 views; UF-SPECT: identical parameters except for 10 s/view and 16 views, reducing the acquisition time from 11 to 3 min)...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28048796/mo-fg-campus-jep2-04-comparison-study-for-ct-and-mr-only-prostate-imrt-treatment-planning-a-framework-for-the-estimation-of-relative-contribution-of-body-contour-discrepancies-tissue-stratification-and-hu-red-conversion-to-the-overall-dose-difference
#16
M Maspero, P R Seevinck, G Schubert, M Hoesl, G J Meijer, M A Viergever, Jjw Lagendijk, Cat van den Berg
PURPOSE: To compare dose of prostate IMRT plans on CT vs MR-based pseudo-CT (pCT). A framework is demonstrated to isolate various confounding factors causing dose differences. This approach will be valuable for medical physicists interested in commissioning strategy of MR-only dose planning. METHODS: A retrospective study was conducted on fourteen prostate patients that underwent CT and MRI scans. MR was equipped with an in-house-developed flat table-top and coil support...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048380/th-ab-202-06-best-in-physics-joint-imaging-therapy-a-real-time-tumor-tracking-using-novel-scatter-imaging-modality-during-lung-sbrt
#17
G Cifter, G Redler, C Lee, A Templeton, D Bernard, J Turian, J Chu, Y Liao
PURPOSE: Compared to traditional radiotherapy techniques, stereotactic body radiation therapy (SBRT) provides more favorable outcomes during the treatment of certain lung tumors. Despite advancements in image guidance, accurate target localization still remains a challenge. In this work, we expand our knowledge of a novel scatter imaging modality in order to develop a real-time tumor localization method using scattered photons from the patient during treatment. METHODS: Images of the QUASAR™ Respiratory Motion Phantom were taken by irradiating it on a Varian TrueBeam accelerator...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048197/su-f-j-175-evaluation-of-metal-artifact-reduction-algorithms-in-computed-tomography-and-their-application-to-radiation-therapy-treatment-planning
#18
H Norris, D Rangaraj, S Kim
PURPOSE: High-Z (metal) implants in CT scans cause significant streak-like artifacts in the reconstructed dataset. This results in both inaccurate CT Hounsfield units for the tissue as well as obscuration of the target and organs at risk (OARs) for radiation therapy planning. Herein we analyze two metal artifact reduction algorithms: GE's Smart MAR and a Metal Deletion Technique (MDT) for geometric and Hounsfield Unit (HU) accuracy. METHODS: A CT-to-electron density phantom, with multiple inserts of various densities and a custom Cerrobend insert (Zeff=76...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048060/su-f-j-223-patterns-of-failure-for-laryngeal-cancer-patients-treated-with-definitive-imrt-comparing-two-different-methods-for-determining-the-origin-of-recurrence-from-follow-up-pet-ct-scans
#19
P Brodin, R Kabarriti, I Vogelius, C Guha, S Kalnicki, M Garg, W Tome
PURPOSE: To determine patterns of failure in laryngeal cancer treated with definitive IMRT by comparing two different methods for identifying the recurrence epicenter on follow-up PET/CT. METHODS: We identified 20 patients treated for laryngeal squamous cell carcinoma with definitive IMRT who had loco-regional recurrence diagnosed on PET/CT. Recurrence PET/CT scans were co-registered with the original treatment planning CT using deformable image registration with the VoxAlign deformation engine in MIM Software...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048033/su-f-t-87-comparison-of-advanced-radiotherapy-techniques-for-post-mastectomy-breast-cancer-patients
#20
D Heins, R Zhang, K Hogstrom, M Sanders
PURPOSE: To determine if bolus electron conformal therapy (Bolus-ECT) combined with intensity modulated x-ray therapy (IMXT) and flattening filter free volumetric modulated arc therapy (FFF-VMAT (6x and 10x)) can maintain equal or better dose coverage than standard volumetric modulated arc therapy (Std-VMAT) while reducing doses to organs at risk (OARs). METHODS: Bolus-ECT with IMXT, FFF-VMAT, and Std-VMAT treatment plans were produced for ten post-mastectomy radiotherapy (PMRT) patients previously treated at our clinic...
June 2016: Medical Physics
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