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https://www.readbyqxmd.com/read/28545597/prefrontal-cortical-thinning-links-to-negative-symptoms-in-schizophrenia-via-the-enigma-consortium
#1
E Walton, D P Hibar, T G M van Erp, S G Potkin, R Roiz-Santiañez, B Crespo-Facorro, P Suarez-Pinilla, N E M van Haren, S M C de Zwarte, R S Kahn, W Cahn, N T Doan, K N Jørgensen, T P Gurholt, I Agartz, O A Andreassen, L T Westlye, I Melle, A O Berg, L Morch-Johnsen, A Færden, L Flyckt, H Fatouros-Bergman, E G Jönsson, R Hashimoto, H Yamamori, M Fukunaga, N Jahanshad, P De Rossi, F Piras, N Banaj, G Spalletta, R E Gur, R C Gur, D H Wolf, T D Satterthwaite, L M Beard, I E Sommer, S Koops, O Gruber, A Richter, B Krämer, S Kelly, G Donohoe, C McDonald, D M Cannon, A Corvin, M Gill, A Di Giorgio, A Bertolino, S Lawrie, T Nickson, H C Whalley, E Neilson, V D Calhoun, P M Thompson, J A Turner, S Ehrlich
BACKGROUND: Our understanding of the complex relationship between schizophrenia symptomatology and etiological factors can be improved by studying brain-based correlates of schizophrenia. Research showed that impairments in value processing and executive functioning, which have been associated with prefrontal brain areas [particularly the medial orbitofrontal cortex (MOFC)], are linked to negative symptoms. Here we tested the hypothesis that MOFC thickness is associated with negative symptom severity...
May 26, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28537778/antibacterial-susceptibilities-of-escherichia-coli-from-community-acquired-urinary-tract-infections-in-the-faroe-islands-associations-with-antibacterial-sales-and-comparison-with-iceland-and-denmark
#2
Marita Debess Magnussen, Hannes Gislason, Shahin Gaini, Karl G Kristinsson
Currently, data on Escherichia coli antibacterial susceptibilities in the Faroe Islands are lacking. The aim was to investigate the antibacterial susceptibilities of E. coli from patients with community-acquired urinary tract infections in the Faroe Islands, correlate with antibacterial sales, and compare with Iceland and Denmark. From 2009 to 2010 and in 2012, 12 general practitioners from the Faroe Islands were recruited to provide urine samples from patients. Antibacterial susceptibilities were determined by disc diffusion testing according to the Clinical and Laboratory Standards Institute methods and criteria...
May 24, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28532490/prevalence-and-determinants-of-childhood-mortality-in-nigeria
#3
Sanni Yaya, Michael Ekholuenetale, Godson Tudeme, Shah Vaibhav, Ghose Bishwajit, Bernard Kadio
BACKGROUND: Childhood mortality has remained a major challenge to public health amongst families in Nigeria and other developing countries. The menace of incessant childhood mortality has been a major concern and this calls for studies to generate new scientific evidence to determine its prevalence and explore predisposing factors associated with it in Nigeria. METHOD: Data was obtained from Nigeria DHS, 2013. The study outcome variable was the total number of children lost by male partners and female partners respectively who were married...
May 22, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28521721/the-importance-of-military-conscripts-for-surveillance-of-human-immunodeficiency-virus-infection-and-risk-behavior-in-thailand
#4
Aladdin Shadyab, Kenrad Nelson, Ram Rangsin
BACKGROUND: The epidemic of human immunodeficiency virus (HIV) infection in Thailand began in 1988 among injection drug users (IDUs) in Bangkok. It soon spread to other populations, especially female sex workers (FSWs) and men attending STD clinics. Routine serologic surveillance for HIV began among military conscripts in 1991. The HIV seroprevalence data from military conscripts provided national surveillance data, since the entire population of 21 year old men were conscripted for 2 years' service in the military by a random process during which 10% of men were selected...
May 17, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28516808/implication-of-foam-sclerosant-inactivation-by-human-whole-blood-in-a-laboratory-setting
#5
Emma B Dabbs, Scott J Dos Santos, Laurensius E Mainsiouw, Alina A Sheikh, Alexis Gkantiragas, Irenie Shiangoli, Mike R Watkins, Jaya L Nemchand, Mark S Whiteley
Background During sclerotherapy, it has been recommended to confirm intravenous placement of the needle by aspirating blood into the sclerosant syringe. This may inactivate some, or all of the sclerosant. Aims To quantify the volume of human blood needed to completely inactivate 1 ml of sodium tetradecyl sulphate, and comparing fresh blood and blood that has been stored in an ethylenediaminetetraacetic acid tube. Methods A series of manual titrations were carried out following a procedure developed at STD Pharmaceutical Products Ltd (Hereford, UK) and listed in the British Pharmacopeia...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28509514/lay-public-s-use-of-a-support-group-for-general-dental-problems
#6
K K Walker, R D Jackson
OBJECTIVE: To categorize and tabulate layperson inquiries made to an Internet dental health support site to identify oral conditions and associated behaviors of concern. METHODS: A retrospective tabulation of wall postings was made from an established dental health support website hosted by WebMD over a 2-year period (April 2013-April 2015). A mixed method approach of content and thematic analysis was used. Content analysis identified content of oral health concerns, while thematic analysis using grounded theory identified themes and beliefs concerning associated behaviors...
September 2016: Community Dental Health
https://www.readbyqxmd.com/read/28507425/a-multigroup-longitudinal-study-of-truant-youths-marijuana-use-depression-and-std-associated-sexual-risk-behavior
#7
Richard Dembo, Julie Krupa, Jennifer Wareham, James Schmeidler, Ralph J DiClemente
Truant youth are likely to engage in a number of problem behaviors, including sexual risky behaviors. Previous research involving non-truant youth has found sexual risk behaviors to be related to marijuana use and depression, with differential effects for male and female youth. Using data collected in a NIDA funded, prospective intervention project, results are reported of a male-female, multi-group, longitudinal analysis of the relationships among truant youth baseline sexual risk behavior, marijuana use, and depression, and their sexual risk behavior over four follow-up time points...
2017: Journal of Child & Adolescent Substance Abuse
https://www.readbyqxmd.com/read/28506113/the-occurrence-of-ryegrass-staggers-and-heat-stress-in-sheep-grazing-ryegrass-endophyte-associations-with-diverse-alkaloid-profiles
#8
L R Fletcher, S C Finch, B L Sutherland, G deNicolo, W J Mace, C van Koten, D E Hume
AIMS: To compare ryegrass pastures infected with endophytes producing diverse alkaloids for their ability to cause ryegrass staggers in grazing lambs; to compare respiration rates and rectal temperatures of these lambs after exposure to heat stress, and to compare liveweight gains during the study period. METHODS: Ryegrass pastures of cultivar Trojan infected with NEA endophytes, branded NEA2 (T-NEA2), endophyte-free Trojan (T-NIL), Samson infected with standard endophyte (S-STD), Samson infected with AR37 endophyte (S-AR37) and endophyte-free Samson (S-NIL), were grazed by lambs (n=30 per cultivar) for up to 48 days in February and March of 2012 and 2013...
May 25, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28505110/green-tea-polyphenols-mimicking-the-effects-of-dietary-restriction-ameliorate-high-fat-diet-induced-kidney-injury-via-regulating-autophagy-flux
#9
Xiao Xie, Weijie Yi, Piwei Zhang, Nannan Wu, Qiaoqiao Yan, Hui Yang, Chong Tian, Siyun Xiang, Miying Du, Eskedar Getachew Assefa, Xuezhi Zuo, Chenjiang Ying
Epidemiological and experimental studies reveal that Western dietary patterns contribute to chronic kidney disease, whereas dietary restriction (DR) or dietary polyphenols such as green tea polyphenols (GTPs) can ameliorate the progression of kidney injury. This study aimed to investigate the renal protective effects of GTPs and explore the underlying mechanisms. Sixty Wistar rats were randomly divided into 6 groups: standard diet (STD), DR, high-fat diet (HFD), and three diets plus 200 mg/kg(bw)/day GTPs, respectively...
May 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28502103/reduced-platelet-aggregation-in-women-after-intercourse-a-possible-role-for-the-cyclooxygenase-pathway
#10
Gabriel Mayoral-Andrade, Laura Pérez-Campos-Mayoral, Abraham Majluf-Cruz, Eduardo Perez-Campos Mayoral, Carlos Perezcampos Mayoral, Ana Rocha-Núñez, Margarito Martinez, Edgar Zenteno, Leticia Hernandez-Gonzalez, María Guadalupe López Juan, Alma Dolores Pérez-Santiago, Eduardo Pérez-Campos
We hypothesise that molecules in the cyclooxygenase pathway affect platelet activity when seminal fluid (SF) is present. We considered the influence of SF on platelet aggregation in women, and believe that the prostanoids in SF signalling are significant. Thirty-one female subjects were studied, 20 of whom were sexually active. Male partners were given either aspirin or indomethacin to inhibit cyclooxygenase. The 6-keto prostaglandin F1α (6-keto PGF1α) and prostaglandin E metabolite (PGE-M) in SF were measured by competitive assay...
May 14, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28499993/robust-2d-3d-registration-optimization-for-motion-compensation-during-3d-trus-guided-biopsy-using-learned-prostate-motion-data
#11
Tharindu De Silva, Derek Cool, Jing Yuan, Cesare Romagnoli, Jagath Samarabandu, Aaron Fenster, Aaron Ward
In magnetic resonance (MR)-targeted, 3D transrectal ultrasound (TRUS)-guided biopsy, prostate motion during the procedure increases the needle targeting error and limits the ability to accurately sample MR-suspicious tumour volumes. The robustness of 2D-3D registration methods for prostate motion compensation is impacted by local optima in the search space. In this paper, we analysed prostate motion characteristics and investigated methods to incorporate such knowledge into the registration optimization framework to improve robustness against local optima...
May 10, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28499291/a-survey-of-25-north-carolina-health-departments-districts-on-knowledge-attitudes-and-current-practices-to-seeking-reimbursement-from-third-party-payers-for-sexually-transmitted-disease-services
#12
Cheryl L Kovar, Susan Carter
BACKGROUND: North Carolina Administrative Code 10A Chapter 41A.0204 (a) states "local health departments shall provide diagnosis, testing, treatment, follow-up, and preventive services for syphilis, gonorrhea, chlamydia, … These services shall be provided upon request and at no charge to the patient." Although health departments/districts may bill governmental or nongovernmental insurance providers for sexually transmitted disease (STD) services, current billing practices are unknown...
June 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28489257/unsaturated-long-chain-fatty-acids-are-preferred-ferritin-ligands-enhancing-iron-biomineralization
#13
Serena Zanzoni, Katiuscia Pagano, Mariapina D'Onofrio, Michael Assfalg, Silvia Ciambellotti, Caterina Bernacchioni, Paola Turano, Silvio Aime, Laura Ragona, Henriette Molinari
Ferritin is a ubiquitous nanocage protein, which can accommodate up to thousands of iron atoms inside its cavity. Besides its iron storage function, a new role as fatty acid binder has been proposed for this protein. The interaction of apo horse spleen ferritin (HoSF) with a variety of lipids has been here investigated through NMR ligand-based experiments, to provide new insights into the mechanism of ferritin/lipid interactions and the link with iron mineralization. 1D DOSY and STD NMR experiments established a stronger interaction of ferritin with unsaturated fatty acids with respect to saturated fatty acids, detergents and bile acids...
May 10, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28475791/prevention-and-control-of-multidrug-resistant-gram-negative-bacteria-in-adult-intensive-care-units-a-systematic-review-and-network-meta-analysis
#14
Nattawat Teerawattanapong, Kirati Kengkla, Piyameth Dilokthornsakul, Surasak Saokaew, Anucha Apisarnthanarak, Nathorn Chaiyakunapruk
Background: This study evaluated the relative efficacy of strategies for the prevention of multidrug-resistant gram-negative bacteria (MDR-GNB) in adult intensive care units (ICUs). Methods: A systematic review and network meta-analysis was performed; searches of the Cochrane Library, PubMed, Embase, and CINAHL (Cumulative Index to Nursing and Allied Health Literature) included all randomized controlled trials and observational studies conducted in adult patients hospitalized in ICUs and evaluating standard care (STD), antimicrobial stewardship program (ASP), environmental cleaning (ENV), decolonization methods (DCL), or source control (SCT), simultaneously...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28473765/feature-detection-in-visual-cortex-during-different-functional-states
#15
Pavel Esir, Alexander Simonov, Misha Tsodyks
Cortical activity exhibits distinct characteristics in different functional states. In awake behaving animals it shows less synchrony, while in rest or sleeping state cortical activity is most synchronous. Previous studies showed that switching between functional states can change the efficiency of flowing sensory information. Switching between functional states can be triggered by releasing neuromodulators which affect neurotransmitter release probability and depolarization of cortical neurons. In this work we focus on studying primary visual area V1, by using firing rate ring model with short-term synaptic depression (STD)...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28471812/comparisons-of-noninvasive-methods-used-to-assess-exercise-stroke-volume-in-hfpef
#16
Erik H Van Iterson, Thomas P Olson, Barry A Borlaug, Bruce D Johnson, Eric M Snyder
INTRODUCTION: Cardiopulmonary exercise testing (CPET) plays an important role in properly phenotyping signs and symptoms of heart failure with preserved ejection fraction (HFpEF). The prognostic value of CPET is strengthened when accompanied by cardiac hemodynamic measurements. Although recognized as the 'Gold' standard, cardiac catheterization is impractical for routine CPET. Thus, advancing the scientific/methodologic understanding of noninvasive techniques for exercise cardiac hemodynamic assessment is clinically impactful in HFpEF...
May 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28471462/the-role-of-metals-in-mammalian-olfaction-of-low-molecular-weight-organosulfur-compounds
#17
REVIEW
Eric Block, Victor S Batista, Hiroaki Matsunami, Hanyi Zhuang, Lucky Ahmed
Covering: up to the end of 2017While suggestions concerning the possible role of metals in olfaction and taste date back 50 years, only recently has it been possible to confirm these proposals with experiments involving individual olfactory receptors (ORs). A detailed discussion of recent experimental results demonstrating the key role of metals in enhancing the response of human and other vertebrate ORs to specific odorants is presented against the backdrop of our knowledge of how the sense of smell functions both at the molecular and whole animal levels...
May 10, 2017: Natural Product Reports
https://www.readbyqxmd.com/read/28467493/p38-mapk-activation-and-h3k4-trimethylation-is-decreased-by-lactate-in-vitro-and-high-intensity-resistance-training-in-human-skeletal-muscle
#18
Lena Willkomm, Sebastian Gehlert, Daniel Jacko, Thorsten Schiffer, Wilhelm Bloch
Exercise induces adaptation of skeletal muscle by acutely modulating intracellular signaling, gene expression, protein turnover and myogenic activation of skeletal muscle stem cells (Satellite cells, SCs). Lactate (La)-induced metabolic stimulation alone has been shown to modify SC proliferation and differentiation. Although the mechanistic basis remains elusive, it was demonstrated that La affects signaling via p38 mitogen activated protein kinase (p38 MAPK) which might contribute to trimethylation of histone 3 lysine 4 (H3K4me3) known to regulate satellite cell proliferation and differentiation...
2017: PloS One
https://www.readbyqxmd.com/read/28463626/responses-of-juvenile-black-tailed-prairie-dogs-cynomys-ludovicianus-to-a-commercially-produced-oral-plague-vaccine-delivered-at-two-doses
#19
Elsa M Cárdenas-Canales, Lisa L Wolfe, Daniel W Tripp, Tonie E Rocke, Rachel C Abbott, Michael W Miller
We confirmed safety and immunogenicity of mass-produced vaccine baits carrying an experimental, commercial-source plague vaccine (RCN-F1/V307) expressing Yersinia pestis V and F1 antigens. Forty-five juvenile black-tailed prairie dogs ( Cynomys ludovicianus ) were randomly divided into three treatment groups (n=15 animals/group). Animals in the first group received one standard-dose vaccine bait (5×10(7) plaque-forming units [pfu]; STD). The second group received a lower-dose bait (1×10(7) pfu; LOW). In the third group, five animals received two standard-dose baits and 10 were left untreated but in contact...
May 2, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28458267/does-the-combined-intervention-program-matter-for-college-attending-hispanic-and-other-minority-young-adults
#20
Thankam S Sunil, Xiaohe Xu, Michelle Mutchler, Frederick Casanova
This evaluation study reports the effects of a combined alcohol-use and sex education intervention program on the knowledge, attitudes, and risk-taking behaviors among college-attending Hispanic and other minority young adults. A random sample of Hispanic, Black, and other racial minority college students aged 18-24 was selected to participate in an intervention study from 2014 to 2016 at a minority-serving institution (MSI) in South Texas. Results show that the combined intervention program has significantly increased minority young adults' awareness of risks associated with unprotected sex, safe-sex negotiation skills, and HIV knowledge...
2017: Journal of Health Care for the Poor and Underserved
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