Munenori Ishibashi, Joyce Keung, Catherine W Morgans, Sue A Aicher, James R Carroll, Joshua H Singer, Li Jia, Wei Li, Iris Fahrenfort, Christophe P Ribelayga, Stephen C Massey
Electrical coupling, mediated by gap junctions, contributes to signal averaging, synchronization, and noise reduction in neuronal circuits. In addition, gap junctions may also provide alternative neuronal pathways. However, because they are small and especially difficult to image, gap junctions are often ignored in large-scale 3D reconstructions. Here, we reconstruct gap junctions between photoreceptors in the mouse retina using serial blockface-scanning electron microscopy, focused ion beam-scanning electron microscopy, and confocal microscopy for the gap junction protein Cx36...
April 26, 2022: ELife