keyword
MENU ▼
Read by QxMD icon Read
search

serum ferritin level

keyword
https://www.readbyqxmd.com/read/28099398/utilizing-a-novel-mobile-health-selfie-application-to-improve-compliance-to-iron-chelation-in-pediatric-patients-receiving-chronic-transfusions
#1
Sarah Leonard, Lindsay M Anderson, Jude Jonassaint, Charles Jonassaint, Nirmish Shah
Iron chelation therapy can prevent iron overload for pediatric patients with sickle cell disease and β-thalassemia major; however, adherence is suboptimal. Therefore, we developed an intensive training program (ITP), to improve medication management and disease knowledge. The objectives were to determine feasibility of the ITP and its preliminary impact on adherence, disease knowledge, and health outcomes. Pediatric patients were recruited to participate in the ITP over a 90-day period and were followed for 6 months...
January 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28098099/the-evaluation-of-the-relationship-between-serum-levels-of-interleukin-6-and-interleukin-10-and-metabolic-acidosis-in-hemodialysis-patients
#2
Narges Sadat Zahed, Saghar Chehrazi
Chronic kidney disease is defined as progressive kidney dysfunction. The levels of various cytokines increase in hemodialysis (HD) patients. High levels of interleukins (ILs) and presence of metabolic acidosis are described as independent risk factors for morbidity and mortality in these patients. This study was designed to evaluate the relationship between IL-6 and IL-10 and serum bicarbonate and metabolic acidosis in HD patients. In this analytical crosssectional study, patients referred to the HD units of Loghman Hakim and Shahid Ashrafi Esfahani Hospitals were randomly selected...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28095043/serum-insulin-growth-factor-1-in-lebanese-schoolchildren-and-its-relation-to-vitamin-d-and-ferritin-levels
#3
Marie-Hélène Gannagé-Yared, Elise Chahine, Vanessa Farah, Tony Ibrahim, Nadia Asmar, Georges Halaby
OBJECTIVE: The aim of our study is to establish reference values for IGF-1 in Lebanese schoolchildren, and to evaluate the relationship between IGF-1 and age, gender, body mass index (BMI),vitamin D and ferritin. METHODS: In this cross-sectional study, 952 Lebanese schoolchildren (495 boys and 457 girls) aged 8-18 years, were included. Blood samples were taken from 10 schools of different socioeconomic status. Chemiluminescent immunoassays were used for IGF-1, 25(OH)D, testosterone and ferritin measurements...
January 17, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28073037/amino-acid-chelated-iron-versus-an-iron-salt-in-the-treatment-of-iron-deficiency-anemia-with-pregnancy-a-randomized-controlled-study
#4
Ghada Abdel Fattah Abdel Moety, Ahmed Mahmoud Ali, Reham Fouad, Wafaa Ramadan, Doaa Shafie Belal, Hisham Mamdouh Haggag
OBJECTIVE: The aim of this study was to compare the efficacy and tolerability of iron amino acid chelate (IAAC) and ferrous fumarate (FF) in treatment of iron deficiency anemia (IDA) with pregnancy. STUDY DESIGN: A total of 150 pregnant women having iron deficiency anemia (IDA) were randomized to receive either IAAC or FF for 12 weeks. Hemoglobin, red cell indices, serum iron, and serum ferritin were measured at baseline and then 4, 8, and 12 weeks after treatment...
January 3, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28068286/pathobiochemical-mechanisms-relating-iron-homeostasis-to-parameters-of-inflammatory-activity-and-autoimmune-disorders-in-rheumatoid-arthritis
#5
Katya I Stefanova, Ginka T Delcheva, Ana I Maneva, Anastas Z Batalov, Mariela G Geneva-Popova, Rositza V Karalilova, Kiril K Simitchiev
AIM: To find the correlations between the parameters of iron homeostasis, inflammatory activity and autoimmune disorders in rheumatoid arthritis (RA). MATERIALS AND METHODS: The present study included 114 patients with RA and 42 healthy controls. We determined the parameters of iron homeostasis: serum iron, total iron binding capacity (TIBC), ferritin and soluble transferrin receptor (sTfR), the parameters of inflammatory activity: C-reactive protein (CRP), interleukin-6 (IL-6) and prohepcidin, and the parameters of autoimmune disorders: rheumatoid factor (RF), anti-cyclic citrullinated peptide (antiCCP) antibodies, and DAS 28...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28063380/hydroxytyrosol-supplementation-increases-vitamin-c-levels-in-vivo-a-human-volunteer-trial
#6
Eduardo Lopez-Huertas, Juristo Fonolla
Hydroxytyrosol (HT) is a main phenolic component of olive oil. In this study, we investigated the safety and effects produced by HT purified (99.5%) from olive mill waste. HT was administered at a daily dosage of 45mg for 8 weeks to volunteers with mild hyperlipidemia (n=14). We measured markers of cardiovascular disease risk, enzyme markers of several clinical conditions, hematology, antioxidant parameters, vitamins and minerals at baseline (T0), 4 weeks (T4) and 8 weeks (T8). The values obtained at T4 and T8 were compared with baseline...
December 26, 2016: Redox Biology
https://www.readbyqxmd.com/read/28062678/facility-practice-variation-to-help-understand-the-effects-of-public-policy-insights-from-the-dialysis-outcomes-and-practice-patterns-study-dopps
#7
Douglas S Fuller, Bruce M Robinson
Recent Centers for Medicare & Medicaid Services policies have used dialysis facility practice variation to develop public ratings and adjust payments. In the Dialysis Facility Compare star rating system (DFC SRS), facility-relative rates of performance-based clinical measures varied nearly two-fold for mortality (standardized mortality ratio; 10th/90th percentiles: 0.71, 1.34) and hospitalization (standardized hospitalization ratio; 10th/90th percentiles: 0.64, 1.37), and nearly four-fold for transfusion (standardized transfusion ratio; 10th/90th percentiles: 0...
January 6, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28060459/circulating-ferritin-concentrations-and-risk-of-type-2-diabetes-in-japanese
#8
Shamima Akter, Akiko Nanri, Keisuke Kuwahara, Yumi Matsushita, Tohru Nakagawa, Maki Konishi, Toru Honda, Shuichiro Yamamoto, Takeshi Hayashi, Mitsuhiko Noda, Tetsuya Mizoue
AIMS/INTRODUCTION: Higher iron storage has been linked to increased risk of type 2 diabetes, but little is known about the mediator of this association. Here, we prospectively investigated the association between circulating ferritin, a marker of iron storage, and the incidence of type 2 diabetes among Japanese. METHODS: Subjects were 4754 employees who attended a comprehensive health checkup in 2008-2009 and donated blood for the study. During 5 years of follow-up, diabetes was identified based on plasma glucose, glycated hemoglobin, and self-report...
January 6, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28054602/identification-of-guanosine-5-diphosphate-as-potential-iron-mobilizer-preventing-the-hepcidin-ferroportin-interaction-and-modulating-the-interleukin-6-stat-3-pathway
#9
Stanzin Angmo, Neha Tripathi, Sheenu Abbat, Shailesh Sharma, Shelley Sardul Singh, Avishek Halder, Kamalendra Yadav, Geeta Shukla, Rajat Sandhir, Vikas Rishi, Prasad V Bharatam, Hariom Yadav, Nitin Kumar Singhal
Hepcidin, a peptide hormone, is a key regulator in mammalian iron homeostasis. Increased level of hepcidin due to inflammatory conditions stimulates the ferroportin (FPN) transporter internalization, impairing the iron absorption; clinically manifested as anemia of inflammation (AI). Inhibiting hepcidin-mediated FPN degradation is proposed as an important strategy to combat AI. A systematic approach involving in silico, in vitro, ex vivo and in vivo studies is employed to identify hepcidin-binding agents. The virtual screening of 68,752 natural compounds via molecular docking resulted into identification of guanosine 5'-diphosphate (GDP) as a promising hepcidin-binding agent...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28052375/unexplained-isolated-hyperferritinemia-without-iron-overload
#10
Giulia Ravasi, Sara Pelucchi, Raffaella Mariani, Marco Casati, Federico Greni, Cristina Arosio, Irene Pelloni, Silvia Majore, Paolo Santambrogio, Sonia Levi, Alberto Piperno
Although hyperferritinemia may be reflective of elevated total body iron stores, there are conditions in which ferritin levels are disproportionately elevated relative to iron status. Autosomal dominant forms of hyperferritinemia due to mutations in the L-ferritin IRE or in A helix of L-ferritin gene have been described, however cases of isolated hyperferritinemia still remain unsolved. We describe 12 Italian subjects with unexplained isolated hyperferritinemia (UIH). Four probands have affected siblings, but no affected parents or offspring...
January 4, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28046068/relationship-between-hemoglobin-levels-corrected-by-interdialytic-weight-gain-and-mortality-in-japanese-hemodialysis-patients-miyazaki-dialysis-cohort-study
#11
Tatsunori Toida, Takashi Iwakiri, Yuji Sato, Hiroyuki Komatsu, Kazuo Kitamura, Shouichi Fujimoto
BACKGROUND: Although hemoglobin (Hb) levels are affected by a change in the body fluid status, the relationship between Hb levels and mortality while taking interdialytic weight gain (IDWG) at blood sampling into account has not yet been examined in hemodialysis patients. STUDY DESIGN: Cohort study. SETTING, PARTICIPANTS: Data from the Miyazaki Dialysis cohort study, including 1375 prevalent hemodialysis patients (median age (interquartile range), 69 (60-77) years, 42...
2017: PloS One
https://www.readbyqxmd.com/read/28046016/iron-status-in-attention-deficit-hyperactivity-disorder-a-systematic-review-and-meta-analysis
#12
Yan Wang, Lan Huang, Li Zhang, Yi Qu, Dezhi Mu
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children. However, the pathogenesis of ADHD remains unclear. Iron, an important trace element, is implicated in brain function and dopaminergic activity. Recent studies have investigated the association between iron deficiency and ADHD, but the results are inconsistent. METHODS: A systemic search of MEDLINE, EMBASE, Web of Science and Cochrane Library databases was supplemented by manual searches of references of key retrieved articles...
2017: PloS One
https://www.readbyqxmd.com/read/28043306/diagnostic-accuracy-of-serum-iron-and-total-iron-binding-capacity-tibc-in-iron-deficiency-state
#13
Naveed Asif, Aamir Ijaz, Tariq Rafi, Zujaja Hina Haroon, Saima Bashir, Muhammad Ayyub
OBJECTIVE: To determine the diagnostic accuracy of serum iron and total iron binding capacity (TIBC) in detection of iron deficiency. STUDY DESIGN: Descriptive, analytical study. PLACE AND DURATION OF STUDY: Department of Chemical Pathology and Endocrinology, from January 2013 to October 2015. METHODOLOGY: Data of 1,815 patients with results of serum iron, TIBC and ferritin from January 2013 to October 2015 was retrieved from Laboratory information System (LIMS) of AFIP...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28031779/brain-derived-neurotrophic-factor-plasma-levels-and-premature-cognitive-impairment-dementia-in-type-2-diabetes
#14
Blanca Murillo Ortíz, Joel Ramírez Emiliano, Edna Ramos-Rodríguez, Sandra Martínez-Garza, Hilda Macías-Cervantes, Sergio Solorio-Meza, Texar Alfonso Pereyra-Nobara
AIM: To assess the relationship of brain-derived neurotrophic factor (BDNF) with cognitive impairment in patients with type 2 diabetes. METHODS: The study included 40 patients with diabetes mellitus type 2 (DM2), 37 patients with chronic kidney disease in hem dialysis hemodialysis therapy (HD) and 40 healthy subjects. BDNF in serum was quantified by ELISA. The Folstein Mini-Mental State Examination was used to evaluate cognitive impairment. RESULTS: The patients with DM2 and the patients in HD were categorized into two groups, with cognitive impairment and without cognitive impairment...
December 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/28031193/associations-of-dietary-lifestyle-and-sociodemographic-factors-with-iron-status-in-chinese-adults-a-cross-sectional-study-in-the-china-health-and-nutrition-survey
#15
Peter J Hu, Sylvia H Ley, Shilpa N Bhupathiraju, Yanping Li, Dong D Wang
BACKGROUND: Although a high prevalence of anemia and related disease burden have been documented in China, limited evidence is available on the current population-level iron status and risk factors for iron imbalance. OBJECTIVE: We explored the associations of dietary, lifestyle, and sociodemographic factors with iron status in Chinese adults. DESIGN: Our study population consisted of 7672 adults aged 18-65 y from the 2009 China Health and Nutrition Survey...
December 28, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28019032/severe-cardiac-iron-toxicity-in-two-adults-with-sickle-cell-disease
#16
Hellen Oduor, Caterina P Minniti, Alessandra Brofferio, Ahmed M Gharib, Khaled Z Abd-Elmoniem, Matthew M Hsieh, John F Tisdale, Courtney D Fitzhugh
BACKGROUND: Use of chronic blood transfusions as a treatment modality in patients with blood disorders places them at risk for iron overload. Since patients with β-thalassemia major (TM) are transfusion-dependent, most studies on iron overload and chelation have been conducted in this population. While available data suggest that compared to TM, patients with sickle cell disease (SCD) have a lower risk of extrahepatic iron overload, significant iron overload can develop. Further, previous studies have demonstrated a direct relationship between iron overload and morbidity and mortality rates in SCD...
December 26, 2016: Transfusion
https://www.readbyqxmd.com/read/28013381/pilot-study-of-the-effect-of-cholecalciferol-supplementation-on-hepcidin-in-children-with-chronic-kidney-disease-results-of-the-d-fense-trial
#17
Meredith A Atkinson, Stephen P Juraschek, Michael S Bertenthal, Barbara Detrick, Susan L Furth, Edgar R Miller
BACKGROUND: Hepcidin is a key mediator of the anemia of chronic kidney disease (CKD). There is emerging evidence that 25-hydroxyvitamin D (25D) regulates hepcidin production. METHODS: A randomized controlled trial of daily vitamin D supplementation for 12 weeks was performed with the aim to test the effects of 4000 versus 400 IU of cholecalciferol on serum hepcidin levels in children with non-dialysis CKD recruited at a tertiary care children's hospital. Hepcidin was quantified using a validated competitive enzyme-linked immunosorbent assay...
December 24, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28009442/predictive-factors-for-anemia-response-to-erythropoiesis-stimulating-agents-in-myelofibrosis
#18
Juan-Carlos Hernández-Boluda, Juan-Gonzalo Correa, Regina García-Delgado, Joaquín Martínez-López, Alberto Alvarez-Larrán, María-Laura Fox, Valentín García-Gutiérrez, Manuel Pérez-Encinas, Francisca Ferrer-Marín, María-Isabel Mata-Vázquez, José-María Raya, Natalia Estrada, Silvia García, Ana Kerguelen, María-Antonia Durán, Manuel Albors, Francisco Cervantes
OBJECTIVE: Erythropoiesis-stimulating agents (ESAs) are commonly used to treat the anemia of myelofibrosis (MF), but information on the predictors of response is limited. METHODS: Results of ESA therapy were analyzed in 163 MF patients with severe anemia, most of whom had inadequate erythropoietin (EPO) levels (<125 U/L) at treatment start. RESULTS: According to the revised criteria of the International Working Group for Myelofibrosis Treatment and Research, anemia response was achieved in 86 patients (53%)...
December 23, 2016: European Journal of Haematology
https://www.readbyqxmd.com/read/28008293/hormonal-and-echocardiographic-abnormalities-in-adult-patients-with-sickle-cell-anemia-in-bahrain
#19
Taysir S Garadah, Ahmed A Jaradat, Mohammed E Alalawi, Adla B Hassan
BACKGROUND: Adrenal, thyroid, and parathyroid gland hormonal changes are recognized in children with homozygous (HbSS) sickle-cell anemia (SCA), but are not clear in adult patients with SCA. AIM: To assess the metabolic and endocrine abnormalities in adult patients with SCA and evaluate left ventricular (LV) systolic and diastolic functions compared with patients with no SCA and further study the relationship between serum levels of cortisol, free thyroxine (T4), and testosterone with serum ferritin...
2016: Journal of Blood Medicine
https://www.readbyqxmd.com/read/28006888/iron-parameters-prohepcidin-and-soluble-transferrin-receptor-levels-in-obese-children
#20
Güzide Doğan, Nesibe Andiran, Nurullah Çelik, Sema Uysal
BACKGROUND: Iron deficiency is common in obese children although the underlying mechanism is unclear. Several studies have investigated the relation between iron deficiency and obesity, but studies focusing on children are rare. The aim was to investigate the associations between iron parameters, prohepcidin and soluble transferrin receptor levels in obese children. METHODS: A total of 110 children, ranging in age from 6-16, 50 with primary obesity and 60 healthy children and adolescents, were enrolled...
December 22, 2016: Minerva Pediatrica
keyword
keyword
11746
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"