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https://www.readbyqxmd.com/read/29518886/curvas-de-fusi%C3%A3-n-de-regiones-gen%C3%A3-micas-espec%C3%A3-ficas-una-herramienta-prometedora-para-el-diagn%C3%A3-stico-y-tipificaci%C3%A3-n-de-las-especies-causantes-de-la-leishmaniasis-cut%C3%A3-nea-en-colombia
#1
Johana Marin, Daniel Urrea, Carlos Muskus, María Clara Echeverry, Ana María Mejía, Omar Triana
Introducción. La leishmaniasis cutánea es una enfermedad causada por parásitos del género Leishmania que tiene gran incidencia en Colombia. El diagnóstico y la identificación de la especie infecciosa son factores críticos en el momento de escoger e iniciar el tratamiento. Actualmente, los métodos de diagnóstico y tipificación requieren procedimientos complejos, por lo que es necesario validar nuevos marcadores moleculares y métodos que simplifiquen el proceso.Objetivo. Desarrollar una herramienta basada en la reacción en cadena de la polimerasa (PCR) con curvas de fusión (High Resolution Melting; PCR-HRM) para el diagnóstico y tipificación de las tres especies de Leishmania de importancia epidemiológica en casos de leishmaniasis cutánea en Colombia...
December 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28977219/severity-and-workload-related-to-adverse-events-in-the-icu
#2
Clarita Terra Rodrigues Serafim, Magda Cristina Queiroz Dell'Acqua, Meire Cristina Novelli E Castro, Wilza Carla Spiri, Hélio Rubens de Carvalho Nunes
Objective: To analyze whether an increase in patient severity and nursing workload are correlated to a greater incidence of adverse events (AEs) in critical patients. Method: A prospective single cohort study was performed on a sample of 138 patients hospitalized in an intensive care unit (ICU). Results: A total of 166 AEs, occurred, affecting 50.7% of the patients. Increased patient severity presented a direct relationship to the probability of AEs occurring...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28746528/simple-motor-tasks-independently-predict-extubation-failure-in-critically-ill-neurological-patients
#3
Fernanda Machado Kutchak, Marcelo de Mello Rieder, Josué Almeida Victorino, Carla Meneguzzi, Karla Poersch, Luiz Alberto Forgiarini, Marino Muxfeldt Bianchin
Objective: To evaluate the usefulness of simple motor tasks such as hand grasping and tongue protrusion as predictors of extubation failure in critically ill neurological patients. Methods: This was a prospective cohort study conducted in the neurological ICU of a tertiary care hospital in the city of Porto Alegre, Brazil. Adult patients who had been intubated for neurological reasons and were eligible for weaning were included in the study. The ability of patients to perform simple motor tasks such as hand grasping and tongue protrusion was evaluated as a predictor of extubation failure...
May 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28627182/predictive-factors-of-hypertriglyceridemia-in-inhospital-patients-during-total-parenteral-nutrition
#4
Maria Julia Ocón Bretón, Ana Isabel Ilundain Gonzalez, Jara Altemir Trallero, Ana Agudo Tabuenca, José Antonio Gimeno Orna
Introduction: Total parenteral nutrition (TPN) is a kind of nutritional support indicated for patients whose clinical situation makes it impossible to cover their nutritional requirements enterally. Despite the fact that TPN is a safe and effective therapy, some complications have been described. One of the most frequent is hypertriglyceridemia. The etiology of this metabolic complication is complex and multifactorial. Objetive: The aim of this work was to determine risk factors associated with the development of hypertrilgyceridemia in adult inhospital non critical patients who carry TPN for a short term...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28591294/impact-of-critical-care-environment-on-burnout-perceived-quality-of-care-and-safety-attitude-of-the-nursing-team
#5
Edinêis de Brito Guirardello
Objective: assess the perception of the nursing team about the environment of practice in critical care services and its relation with the safety attitude, perceived quality of care and burnout level. Method: cross-sectional study involving 114 nursing professionals from the intensive care unit of a teaching hospital. The following instruments were used: Nursing Work Index-Revised, Maslach Burnout Inventory and the Safety Attitude Questionnaire. Results: the professionals who perceived greater autonomy, good relationships with the medical team and better control over the work environment presented lower levels of burnout, assessed the quality of care as good and reported a positive perception on the safety attitude for the domain job satisfaction...
June 5, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28585855/our-great-forgotten-chronic-respiratory-sufferers
#6
María Luisa Bordejé Laguna
Lung’s own properties make that nutritional support, besides covering the requirements can modulate its infl ammatory response. Lung tissue has a low glucose stock. Fatty acids are the main energy producer of type II pneumocytes, which use them in order to form phospholipids, essential for surfactant whose creation and release decrease in acute lung injury (ALI). Glutamine is a good substratum for endocrine cells and type II pneumocytes. Due to high nutritional risk, it is important its assessments in disorders as COPD and acute respiratory distress syndrome (ADRS)...
May 8, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28538781/effects-that-passive-cycling-exercise-have-on-muscle-strength-duration-of-mechanical-ventilation-and-length-of-hospital-stay-in-critically-ill-patients-a-randomized-clinical-trial
#7
RANDOMIZED CONTROLLED TRIAL
Aline Dos Santos Machado, Ruy Camargo Pires-Neto, Maurício Tatsch Ximenes Carvalho, Janice Cristina Soares, Dannuey Machado Cardoso, Isabella Martins de Albuquerque
Objective: To evaluate the effects that passive cycling exercise, in combination with conventional physical therapy, have on peripheral muscle strength, duration of mechanical ventilation, and length of hospital stay in critically ill patients admitted to the ICU of a tertiary care university hospital. Methods: This was a randomized clinical trial involving 38 patients (≥ 18 years of age) on mechanical ventilation who were randomly divided into two groups: control (n = 16), receiving conventional physical therapy; and intervention (n = 22), receiving conventional physical therapy and engaging in passive cycling exercise five days per week...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28513767/capnography-as-a-tool-to-detect-metabolic-changes-in-patients-cared-for-in-the-emergency-setting
#8
REVIEW
Francisco José Cereceda-Sánchez, Jesús Molina-Mula
Objective: to evaluate the usefulness of capnography for the detection of metabolic changes in spontaneous breathing patients, in the emergency and intensive care settings. Methods: in-depth and structured bibliographical search in the databases EBSCOhost, Virtual Health Library, PubMed, Cochrane Library, among others, identifying studies that assessed the relationship between capnography values and the variables involved in blood acid-base balance. Results: 19 studies were found, two were reviews and 17 were observational studies...
May 15, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28117473/perme-intensive-care-unit-mobility-score-and-icu-mobility-scale-translation-into-portuguese-and-cross-cultural-adaptation-for-use-in-brazil
#9
Yurika Maria Fogaça Kawaguchi, Ricardo Kenji Nawa, Thais Borgheti Figueiredo, Lourdes Martins, Ruy Camargo Pires-Neto
Objective: To translate the Perme Intensive Care Unit Mobility Score and the ICU Mobility Scale (IMS) into Portuguese, creating versions that are cross-culturally adapted for use in Brazil, and to determine the interobserver agreement and reliability for both versions. Methods: The processes of translation and cross-cultural validation consisted in the following: preparation, translation, reconciliation, synthesis, back-translation, review, approval, and pre-test...
November 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27982402/physical-methods-for-the-treatment-of-fever-in-critically-ill-patients-a-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Patrícia de Oliveira Salgado, Ludmila Christiane Rosa da Silva, Priscila Marinho Aleixo Silva, Tânia Couto Machado Chianca
OBJECTIVE: To evaluate the effects of physical methods of reducing body temperature (ice pack and warm compression) in critically ill patients with fever. METHOD: A randomized clinical trial involving 102 adult patients with tympanic temperature ≥ 38.3°C of an infectious focus, and randomized into three groups: Intervention I - ice pack associated with antipyretic; Intervention II - warm compress associated with antipyretic; and Control - antipyretic. Tympanic temperature was measured at 15 minute intervals for 3 hours...
September 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/27759788/understanding-the-international-consensus-for-acute-pancreatitis-classification-of-atlanta-2012
#11
Gleim Dias de Souza, Luciana Rodrigues Queiroz Souza, Ronaldo Máfia Cuenca, Bárbara Stephane de Medeiros Jerônimo, Guilherme Medeiros de Souza, Vinícius Martins Vilela
Introduction: Contrast computed tomography and magnetic resonance imaging are widely used due to its image quality and ability to study pancreatic and peripancreatic morphology. The understanding of the various subtypes of the disease and identification of possible complications requires a familiarity with the terminology, which allows effective communication between the different members of the multidisciplinary team. Aim: Demonstrate the terminology and parameters to identify the different classifications and findings of the disease based on the international consensus for acute pancreatitis ( Atlanta Classification 2012)...
July 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/18783711/-recommendations-for-antibiotic-monitoring-in-icu-patients
#12
Francisco Alvarez, Pedro Olaechea, Santiago Grau, Mónica Marín, Alfonso Domínguez, José Martínez-Lanao, Dolors Soy, Manuel Alos, María Victoria, Belén Sádaba, Africa Mediavilla, Daniel Fatela
Monitoring plasma concentrations of antimicrobial agents used to treat infection in critically ill patients is one of the recommended strategies for improving clinical outcome. Drug monitoring has a double aim: to limit adverse events and to increase the effectiveness of the drugs. In clinical practice, however, this approach is mainly limited to monitoring plasma concentrations of vancomycin and aminoglycosides, although future extension to other antimicrobial agents would be desirable. Application of this technique varies considerably between hospitals, and this makes interpretation and comparison of the results obtained difficult...
March 2008: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/18479646/-surveillance-and-control-of-methicillin-resistant-staphylococcus-aureus-in-spanish-hospitals-a-geih-seimc-and-sempsph-consensus-document
#13
Jesús Rodríguez-Baño, Cornelia Bischofberger, Francisco Alvarez-Lerma, Angel Asensio, Teresa Delgado, Dolores García-Arcal, Lola García-Ortega, M Jesús Hernández, Jesús Molina-Cabrillana, Carmen Pérez-Canosa, Miquel Pujol
Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen, both in-hospital and in the community. Although there are several guidelines with recommendations for the control of this microorganism, the measures proposed are not uniformly implemented in Spanish hospitals. The objective of this document is to provide evidence-based recommendations that are applicable to Spanish hospitals, with the aim of reducing transmission of MRSA in our health care centers. The recommendations are divided into the following groups: surveillance, active detection of colonization in patients and health care workers, control measures for colonized or infected patients, decolonization therapy, environmental cleaning and disinfection, antimicrobial consumption, measures for non-hospitalized patients, and others...
May 2008: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/18381043/-recommendations-for-antibiotic-monitoring-in-icu-patients
#14
Francisco Alvarez-Lerma, Pedro Olaechea, Santiago Grau, Mónica Marín, Alfonso Domínguez, José Martínez-Lanao, Dolors Soy, Manuel Alos, María Victoria Calvo, Belén Sádaba, Africa Mediavilla, Daniel Fatela
UNLABELLED: Monitoring plasma concentrations of antimicrobial agents used to treat infection in critically ill patients is one of the recommended strategies for improving clinical outcome. Drug monitoring has a double AIM: to limit adverse events and to increase the effectiveness of the drugs. In clinical practice, however, this approach is mainly limited to monitoring plasma concentrations of vancomycin and aminoglycosides, although future extension to other antimicrobial agents would be desirable...
April 2008: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/17692213/-geipc-seimc-study-group-for-infections-in-the-critically-ill-patient-of-the-spanish-society-for-infectious-diseases-and-clinical-microbiology-and-gtei-semicyuc-working-group-on-infectious-diseases-of-the-spanish-society-of-intensive-medicine-critical-care
#15
P M Olaechea Astigarraga, J Garnacho Montero, S Grau Cerrato, O Rodríguez Colomo, M Palomar Martínez, R Zaragoza Crespo, P Muñoz García-Paredes, E Cerdá Cerdá, F Alvarez Lerma
In recent years, an increment of infections caused by gram-positive cocci has been documented in nosocomial and hospital-acquired-infections. In diverse countries, a rapid development of resistance to common antibiotics against gram-positive cocci has been observed. This situation is exceptional in Spain but our country might be affected in the near future. New antimicrobials active against these multi-drug resistant pathogens are nowadays available. It is essential to improve our current knowledge about pharmacokinetic properties of traditional and new antimicrobials to maximize its effectiveness and to minimize toxicity...
August 2007: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/17663956/-geipc-seimc-and-gtei-semicyuc-recommendations-for-antibiotic-treatment-of-gram-positive-coccal-infections-in-the-critical-patient
#16
P M Olaechea Astigarraga, J Garnacho Montero, S Grau Cerrato, O Rodríguez Colomo, M Palomar Martínez, R Zaragoza Crespo, P Muñoz García-Paredes, E Cerdá Cerdá, F Alvarez Lerma
In recent years, an increment of infections caused by gram-positive cocci has been documented in nosocomial and hospital-acquired infections. In diverse countries, a rapid development of resistance to common antibiotics against gram-positive cocci has been observed. This situation is exceptional in Spain but our country might be affected in the near future. New antimicrobials active against these multi-drug resistant pathogens are nowadays available. It is essential to improve our current knowledge about pharmacokinetic properties of traditional and new antimicrobials to maximize its effectiveness and to minimize toxicity...
August 2007: Medicina Intensiva
https://www.readbyqxmd.com/read/11737996/-risk-and-prognostic-factors-of-pseudomonas-aeruginosa-bacteremia-in-critically-ill-patients
#17
MULTICENTER STUDY
F Alvarez-Lerma, M Pavesi, M Calizay, J Valles, M Palomar et al.
BACKGROUND: To determine risk and prognostic factors in patients admitted to the intensive care unit (ICU) in which an episode of bacteremia caused by Pseudomonas aeruginosa has been diagnosed. PATIENTS AND METHOD: Cohort, observational, prospective, multicenter study. Patients admitted to 30 ICUs in Spain in whom one or more pathogens were isolated from blood cultures were included. RESULTS: In a total of 16,216 patients admitted to the participating ICUs during the study period, 949 episodes of bacteremia were diagnosed In 77 cases (8...
December 8, 2001: Medicina Clínica
https://www.readbyqxmd.com/read/11446909/-cefotaxime-twenty-years-later-observational-study-in-critically-ill-patients
#18
MULTICENTER STUDY
F Alvarez-Lerma, M Palomar, P Olaechea, R Sierra, E Cerda
OBJECTIVE: Afer twenty years of commercial availability of cefotaxime, the objective of this study was to know the reasons and modes of use, administration dosage as well as its effectiveness and tolerance in critically ill patients admitted to Intensive Care Units (ICU) in our country. DESIGN: Open, prospective, observational, multicenter study. SUBJECTS: All patients who had cefotaxime administered in monotherapy or in combination with other antibiotics were included as cases in this study...
May 2001: Enfermedades Infecciosas y Microbiología Clínica
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