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https://www.readbyqxmd.com/read/28938521/beneficial-health-applications-and-medicinal-values-of-pedicularis-plants-a-review
#1
REVIEW
Mohd Iqbal Yatoo, Umesh Dimri, Arumugam Gopalakrishnan, Kumaragurubaran Karthik, Marappan Gopi, Rekha Khandia, Mani Saminathan, Archana Saxena, Mahmoud Alagawany, Mayada Ragab Farag, Ashok Munjal, Kuldeep Dhama
Pedicularis plants (Orobanchaceae), popularly known as lousewort, are found in Asia, Europe, and North America, and have been used in Sowa-Rigpa, the Himalayan art of healing and a traditional system of medicine for treating various ailments in humans. A comprehensive compilation on this valuable medicinal plant is not available, however. The present extensive review provides insight into the salient medicinal properties of Pedicularis plants with respect to various health issues and diseases. Our previous studies on Pedicularis plants from the Changthang region of Ladakh (India) and research advances leading to new developments in this field have prompted this review...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28937339/locked-out
#2
Veronica Johansson, Surjo R Soekadar, Jens Clausen
Brain-computer interfaces (BCIs) can enable communication for persons in severe paralysis including locked-in syndrome (LIS); that is, being unable to move or speak while aware. In cases of complete loss of muscle control, termed "complete locked-in syndrome," a BCI may be the only viable solution to restore communication. However, a widespread ignorance regarding quality of life in LIS, current BCIs, and their potential as an assistive technology for persons in LIS, needlessly causes a harmful situation for this cohort...
October 2017: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
https://www.readbyqxmd.com/read/28936158/bayesian-tractography-using-geometric-shape-priors
#3
Xiaoming Dong, Zhengwu Zhang, Anuj Srivastava
The problem of estimating neuronal fiber tracts connecting different brain regions is important for various types of brain studies, including understanding brain functionality and diagnosing cognitive impairments. The popular techniques for tractography are mostly sequential-tracts are grown sequentially following principal directions of local water diffusion profiles. Despite several advancements on this basic idea, the solutions easily get stuck in local solutions, and can't incorporate global shape information...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28934885/from-bench-to-bedside-current-advancement-on-large-scale-production-of-mesenchymal-stem-cells
#4
Varitsara Bunpetch, Haoyu Wu, Shufang Zhang, Hong Wei Ouyang
Mesenchymal stem cells (MSCs) are the primary cell source in cell therapy and regenerative medicine due to its extraordinary self-renewing capacity and multilineage differentiation potential. Clinical trials involving MSCs are being conducted in a range of human diseases and the number of registered cases is continuously increasing. However, a wide gap exists between the number of MSCs obtainable from the donor site and the number required for implantation to damage tissues, and also between MSC scalability and MSC phenotype stability...
September 21, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28931872/efficient-steam-generation-by-inexpensive-narrow-gap-evaporation-device-for-solar-applications
#5
Matteo Morciano, Matteo Fasano, Uktam Salomov, Luigi Ventola, Eliodoro Chiavazzo, Pietro Asinari
Technologies for solar steam generation with high performance can help solving critical societal issues such as water desalination or sterilization, especially in developing countries. Very recently, we have witnessed a rapidly growing interest in the scientific community proposing sunlight absorbers for direct conversion of liquid water into steam. While those solutions can possibly be of interest from the perspective of the involved novel materials, in this study we intend to demonstrate that efficient steam generation by solar source is mainly due to a combination of efficient solar absorption, capillary water feeding and narrow gap evaporation process, which can also be achieved through common materials...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28926720/recent-advances-in-proteomic-profiling-of-pancreatic-ductal-adenocarcinoma-and-the-road-ahead
#6
Hyunsoo Kim, Joonho Park, Joseph I Wang, Youngsoo Kim
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide. However, there remain many unmet clinical needs, from diagnosis to treatment strategies. The inherent complexity of the molecular characteristics of PDAC has made it difficult to meet these challenges, rendering proteomic profiling of PDAC a critical area of research. Area covered: In this review, we present recent advances in mass spectrometry (MS) and its current application in proteomic studies on PDAC. In addition, we discuss future directions for research that can efficiently incorporate current MS-based technologies that address key issues of PDAC proteomics...
September 19, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/28926687/advanced-nanostructured-anode-materials-for-sodium-ion-batteries
#7
REVIEW
Qidi Wang, Chenglong Zhao, Yaxiang Lu, Yunming Li, Yuheng Zheng, Yuruo Qi, Xiaohui Rong, Liwei Jiang, Xinguo Qi, Yuanjun Shao, Du Pan, Baohua Li, Yong-Sheng Hu, Liquan Chen
Sodium-ion batteries (NIBs), due to the advantages of low cost and relatively high safety, have attracted widespread attention all over the world, making them a promising candidate for large-scale energy storage systems. However, the inherent lower energy density to lithium-ion batteries is the issue that should be further investigated and optimized. Toward the grid-level energy storage applications, designing and discovering appropriate anode materials for NIBs are of great concern. Although many efforts on the improvements and innovations are achieved, several challenges still limit the current requirements of the large-scale application, including low energy/power densities, moderate cycle performance, and the low initial Coulombic efficiency...
September 19, 2017: Small
https://www.readbyqxmd.com/read/28923102/workshop-on-challenges-insights-and-future-directions-for-mouse-and-humanized-models-in-cancer-immunology-and-immunotherapy-a-report-from-the-associated-programs-of-the-2016-annual-meeting-for-the-society-for-immunotherapy-of-cancer
#8
Andrew Zloza, A Karolina Palucka, Lisa M Coussens, Philip J Gotwals, Mark B Headley, Elizabeth M Jaffee, Amanda W Lund, Arlene H Sharpe, Mario Sznol, Derek A Wainwright, Kwok-Kin Wong, Marcus W Bosenberg
Understanding how murine models can elucidate the mechanisms underlying antitumor immune responses and advance immune-based drug development is essential to advancing the field of cancer immunotherapy. The Society for Immunotherapy of Cancer (SITC) convened a workshop titled, "Challenges, Insights, and Future Directions for Mouse and Humanized Models in Cancer Immunology and Immunotherapy" as part of the SITC 31st Annual Meeting and Associated Programs on November 10, 2016 in National Harbor, MD. The workshop focused on key issues in optimizing models for cancer immunotherapy research, with discussions on the strengths and weaknesses of current models, approaches to improve the predictive value of mouse models, and advances in cancer modeling that are anticipated in the near future...
September 19, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28915078/pediatric-specific-end-of-life-care-quality-measures-an-unmet-need-of-a-vulnerable-population
#9
Emily E Johnston, Abby R Rosenberg, Arif H Kamal
We must ensure that the 20,000 US children (age 0 to 19 years) who die as a result of serious illness annually receive high-quality end-of-life care. Ensuring high-quality end-of-life care requires recognition that pediatric end-of-life care is conceptually and operationally different than that for adults. For example, in-hospital adult death is considered an outcome to be avoided, whereas many pediatric families may prefer hospital death. Because pediatric deaths are comparatively rare, not all centers offer pediatric-focused palliative care and hospice services...
September 15, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28911013/invited-commentary-integrating-genomics-and-social-epidemiology-analysis-of-late-life-low-socioeconomic-status-and-the-conserved-transcriptional-response-to-adversity
#10
Daniel W Belsky, Noah Snyder-Mackler
Socially disadvantaged children face increased morbidity and mortality as they age. Understanding mechanisms through which social disadvantage becomes biologically embedded and devising measurements that can track this embedding are critical priorities for research to address social gradients in health. The analysis by Levine et al. (Am J Epidemiol. 2017;186(5):503-509) of genome-wide gene expression in a subsample of US Health and Retirement Study participants suggests important new directions for the field...
September 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28901283/a-systematic-review-of-religious-beliefs-about-major-end-of-life-issues-in-the-five-major-world-religions
#11
Rajshekhar Chakraborty, Areej R El-Jawahri, Mark R Litzow, Karen L Syrjala, Aric D Parnes, Shahrukh K Hashmi
OBJECTIVE: The objective of this study was to examine the religious/spiritual beliefs of followers of the five major world religions about frequently encountered medical situations at the end of life (EoL). METHOD: This was a systematic review of observational studies on the religious aspects of commonly encountered EoL situations. The databases used for retrieving studies were: Ovid MEDLINE In-Process & Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, Ovid PsycINFO, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus...
October 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28899203/an-overview-of-the-advantages-of-keap1-nrf2-system-activation-during-inflammatory-disease-treatment
#12
Nadine Keleku-Lukwete, Mikiko Suzuki, Masayuki Yamamoto
Inflammation can be defined as a protective immune response against harmful exogenous and endogenous stimuli. Nevertheless, prolonged or autoimmune inflammatory response are likely to cause pathological states associated with a production of inflammation-associated molecules along with ROS (reactive oxygen species). KEAP1-NRF2 (Kelch-like ECH-associated protein 1-Nuclear factor erythroid 2-related factor 2) signaling provides a cell protection mechanism against oxidative insults when endogenous stress defense mechanisms are imbalanced...
September 13, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28894637/epidermal-stem-cells-in-skin-wound-healing
#13
REVIEW
Yuanyuan Li, Jamie Zhang, Jiping Yue, Xuewen Gou, Xiaoyang Wu
Significance: Skin serves as a protective barrier for mammals. Epidermal stem cells are responsible for maintaining skin homeostasis. When cutaneous injuries occur, skin homeostasis and integrity are damaged, leading to dire consequences such as acute, chronic, or infected wounds. Skin wound healing is an intrinsic self-saving chain reaction, which is crucial to facilitating the replacement of damaged or lost tissue. Recent Advances: An immense amount of research has uncovered the underlying mechanisms behind the complex and highly regulated wound healing process...
September 1, 2017: Advances in Wound Care
https://www.readbyqxmd.com/read/28894537/lifestyles-in-suburban-populations-a-systematic-review
#14
REVIEW
Samira Khayat, Mahrokh Dolatian, Ali Navidian, Zohreh Mahmoodi, Nasibeh Sharifi, Amir Kasaeian
BACKGROUND: Lifestyle and suburban population are important issues in the field of health. The living conditions of informal settlements can lead to acquisition of an unhealthy lifestyle. OBJECTIVE: This study has been designed to investigate the articles that have been published regarding lifestyle in suburban populations. METHODS: The present research was a systematic review of studies in databases including Iranmedex, Magiran, SID, Irandoc, PubMed, Google Scholar, Science Direct and Scopus, in 2017...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28892287/introduction-to-the-special-issue-20th-century-origins-and-21st-century-developments-of-peer-nomination-methodology
#15
Peter E L Marks
This issue of New Directions for Child and Adolescent Development looks at current practices and recent advances in peer nomination methodology. Peer nominations provide a key method for assessing relationships, social status, and interpersonal behavior. This introductory article begins with a history of peer nomination methods, with a focus on the early origins of peer informant measures and the nature of Moreno's (1934) sociometric methodology (highlighting fundamental differences from the modern sociometric procedure)...
September 2017: New Directions for Child and Adolescent Development
https://www.readbyqxmd.com/read/28886862/understanding-positive-immigrant-youth-adaptation-in-the-context-of-multiculturalism
#16
David L Sam
This commentary highlights some of the strengths of the papers in this special issue focusing on how they advance acculturation research; how they link immigrant youth research with positive youth development and how they provide some insights into understanding how immigrant youth thrive in their adoptive societies. The commentary takes as its point of departure the prototypical research question for immigrant youth research within the perspective of positive youth development and the ultimate goals of acculturation research, i...
September 5, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28876026/-advances-in-platform-compounds-and-polymers-from-vegetable-oils
#17
Xin He, Guiying Wu, Yunjun Yan
Vegetable oil is one of the most potential alternatives of petroleum and has become a hot issue in recent years. This review focuses on the influence of vegetable oil structure on platform compounds and polymers properties, and further systematically introduces their developments and the latest progress. Meanwhile, we also summarized the main confronting problems and the future development directions in the research of oil-based platform compounds and polymers. The review provides useful information for readers to fully understand biochemical engineering of vegetable oils and their prospects...
May 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28875731/outpatient-palliative-cardiology-service-embedded-within-a-heart-failure-clinic-experiences-with-an-emerging-model-of-care
#18
Benjamin Gandesbery, Krista Dobbie, Eiran Z Gorodeski
BACKGROUND: The role of palliative care consultation in the outpatient treatment of patients with symptomatic heart failure (HF) is poorly studied. In August 2015, we created an outpatient palliative care service embedded within the HF clinic at Cleveland Clinic main campus. AIM: To characterize patients cared for by our novel outpatient palliative cardiology service, including their degree of HF, symptoms, comorbidities, topics addressed in clinic, palliative treatments prescribed, advanced directives status, and mortality...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28870022/playing-to-our-human-strengths-to-prepare-medical-students-for-the-future
#19
Julie Chen
We are living in an age where artificial intelligence and astounding technological advances are bringing truly remarkable change to healthcare. Medical knowledge and skills which form the core responsibility of doctors such as making diagnoses may increasingly be delivered by robots. Machines are gradually acquiring human abilities such as deep learning and empathy. What, then is the role of doctors in future healthcare? And what direction should medical schools be taking to prepare their graduates? This article will give an overview of the evolving technological landscape of healthcare and examine the issues undergraduate medical education may have to address...
September 2017: Korean Journal of Medical Education
https://www.readbyqxmd.com/read/28868563/current-progress-in-black-phosphorus-materials-and-their-applications-in-electrochemical-energy-storage
#20
M Qiu, Z T Sun, D K Sang, X G Han, H Zhang, C M Niu
Recently, a new two-dimensional material, single- or few-layered black phosphorus (BP), has attracted considerable attention for applications in electronics, optoelectronics, and batteries due to its unique properties, including large specific surface area, anisotropy, and tunable and direct band gaps. In particular, contributions to electrochemical energy storage devices, such as lithium and sodium ion batteries and supercapacitors, have emerged. However, critical issues remain to be explored before scaled-up commercial production of BP, such as preparation, stability, and performance...
September 21, 2017: Nanoscale
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