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https://www.readbyqxmd.com/read/29135157/-calciuria-as-a-metabolic-marker-for-various-conditions-and-diseases
#1
L V Egshatyan, N G Mokrysheva
The article analyzes the literature on the features of human calcium homeostasis. The authors describe the etiopathogenetic role of calcitropic hormones, the plasma and urine acid-base status, various ions, lifestyle and nutrition and other factors contributing to hypercalciuria due to increased intestinal absorption, bone resorption, impairment of tubular calcium reabsorption, etc. They discuss the role of calciuria as a factor in forming urinary calculi and present their own observations.
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29130403/urinary-iodine-perchlorate-and-thiocyanate-concentrations-in-u-s-lactating-women
#2
Sun Y Lee, Alicia M McCarthy, Hindi E Stohl, Sherrine A Ibrahim, Christina Jeong, Lewis E Braverman, Wendy Siqian Ma, Xuemei He, Jorge H Mestman, Kristin E Schuller, Katherine A Jahreis, Elizabeth N Pearce, Angela M Leung
BACKGROUND: Iodine is an essential micronutrient for thyroid hormone production. Adequate iodine intake and normal thyroid function are important during early development, and breastfed infants rely on maternal iodine excreted in breast milk for their iodine nutrition. The proportion of U.S. women of childbearing age with urinary iodine concentration (UIC) <50µg/L has been increasing, and a subset of lactating women may have inadequate iodine intake. UIC may also be influenced by environmental exposure to perchlorate and thiocyanate, competitive inhibitors of iodine transport into thyroid and lactating mammary glands...
November 12, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29127912/pesticides-contaminated-dust-exposure-risk-diagnosis-and-exposure-markers-in-occupational-and-residential-settings-of-lahore-pakistan
#3
Sidra Waheed, Crispin Halsall, Andrew J Sweetman, Kevin C Jones, Riffat Naseem Malik
There are few studies documenting the dust loaded with pesticides as a potential non-dietary exposure source for occupational worker and populations living near agricultural farms and pesticides formulation plants. In present study we have evaluated the pesticide concentration in dust from potential sites and relevant health risk from dust ingestion. Furthermore, the effect of currently used pesticides was investigated on blood and urine parameters of subjects: farmer, factory worker, urban resident and rural resident and controlled subjects with presumably different levels of exposure...
November 7, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29111902/the-effect-of-cranberry-juice-consumption-on-the-recurrence-of-urinary-tract-infection-relationship-to-baseline-risk-factors
#4
Kevin C Maki, Kristin M Nieman, Arianne L Schild, Kerrie L Kaspar, Christina Khoo
OBJECTIVE: The objective of this study was to assess relationships between clinical predictors of urinary tract infection (UTI) and effects of cranberry juice consumption on recurrence in a post hoc analysis of a 24-week, randomized, double-blind, placebo-controlled, multicenter clinical trial in women with a recent history of UTI. METHODS: Participants consumed a cranberry (n = 185) or placebo (n = 188) beverage (240 mL) daily. Odds ratios (OR) from 20 candidate predictor variables were evaluated in univariate analyses to assess clinical UTI incidence relationships in the placebo group...
November 7, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29106365/validation-of-the-french-canadian-version-of-the-expanded-prostate-cancer-index-composite-epic-in-a-french-canadian-population
#5
Éric Vigneault, Josée Savard, Marie-Hélène Savard, Hans Ivers, Philippe Després, William Foster, André-Guy Martin, Vincent Fradet
INTRODUCTION: This study aims to empirically validate the French-Canadian version of the Expanded Prostate Cancer Index Composite (EPIC), a measure of health-related quality of life for prostate cancer patients. METHODS: 251 participants completed a battery of self-report scales including the French-Canadian version of the EPIC, after having received radiation therapy or radical prostatectomy for prostate cancer. RESULTS: The internal consistency for the urinary incontinence, bowel, and sexual domains of the EPIC-26 was high (Cronbach's alpha coefficients from ...
November 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29105036/is-there-any-association-between-urinary-metabolites-of-polycyclic-aromatic-hydrocarbons-and-thyroid-hormone-levels-in-children-and-adolescents
#6
Roya Kelishadi, Payam Sobhani, Parinaz Poursafa, Mohammad Mehdi Amin, Karim Ebrahimpour, Silva Hovsepian, Marjan Mansourian, Reza Najafi, Mahin Hashemipour
Considering the possible effects of polycyclic aromatic hydrocarbons (PAHs) on thyroid function, the current study aims to investigate the association of PAH urinary metabolites with the level of thyroid hormones in a sample of Iranian children and adolescents. This cross-sectional study was conducted from September 2015 to July 2016 in Isfahan, Iran. Participants were 150 students, aged 6-18 years, who were selected by multistage cluster random sampling from schools of Isfahan province. Blood and urine samples of participants were obtained for measurement of thyroid hormone levels (measured by immunoradiometric assay) and PAH urinary metabolites, including 1-hydroxynaphthalene, 2-hydroxynaphthalene, 9-hydroxyphenanthrene, and 1-hydroxypyrene...
November 5, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29100688/bisphenol-a-and-reproductive-hormones-and-cortisol-in-peripubertal-boys-the-inma-granada-cohort
#7
Vicente Mustieles, Olga Ocón-Hernandez, Lidia Mínguez-Alarcón, Cristina Dávila-Arias, Rocío Pérez-Lobato, Irene Calvente, Juan P Arrebola, Fernando Vela-Soria, Soledad Rubio, Russ Hauser, Nicolás Olea, Mariana F Fernández
INTRODUCTION: Bisphenol A (BPA) is a well-known endocrine disrupting compound. Although several studies have investigated the effect of BPA exposure and reproductive hormones in humans, results have been inconsistent. OBJECTIVE: To explore the cross-sectional relationship between bisphenol A (BPA) exposure and reproductive hormones/cortisol among peripubertal boys. MATERIAL AND METHODS: Urinary BPA and serum hormones were assessed in 172 boys belonging to the INMA "Environment and Childhood" Granada birth cohort in their follow-up at 9-11years of age...
October 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29096595/pleiotropic-actions-of-fgf23
#8
Reinhold G Erben
Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, mainly produced by osteoblasts and osteocytes in response to increased extracellular phosphate and circulating vitamin D hormone. Endocrine FGF23 signaling requires co-expression of the ubiquitously expressed FGF receptor 1 (FGFR1) and the co-receptor α-Klotho (Klotho). In proximal renal tubules, FGF23 suppresses the membrane expression of the sodium-phosphate cotransporters Npt2a and Npt2c which mediate urinary reabsorption of filtered phosphate...
January 1, 2017: Toxicologic Pathology
https://www.readbyqxmd.com/read/29094256/efficacy-of-dexamethasone-suppression-test-during-the-diagnosis-of-primary-pigmented-nodular-adrenocortical-disease-in-chinese-adrenocorticotropic-hormone-independent-cushing-syndrome
#9
Shi Chen, Ran Li, Lin Lu, Lian Duan, Xuebin Zhang, Anli Tong, Hui Pan, Huijuan Zhu, Zhaolin Lu
OBJECTIVE: To evaluate the cut-off value of the ratio of 24 h urinary free cortisol (24 h UFC) levels post-dexamethasone to prior-dexamethasone in dexamethasone suppression test (DST) during the diagnosis of primary pigmented nodular adrenocortical disease in Chinese adrenocorticotropic hormone-independent Cushing syndrome. DESIGN: Retrospective study. PARTICIPANTS: The patients diagnosed with primary pigmented nodular adrenocortical disease (PPNAD, n = 25), bilateral macronodular adrenal hyperplasia (BMAH, n = 27), and adrenocortical adenoma (ADA, n = 84) were admitted to the Peking Union Medical College Hospital from 2001 to 2016...
November 1, 2017: Endocrine
https://www.readbyqxmd.com/read/29090711/the-effect-of-dietary-magnesium-and-caseinphosphopeptides-on-bone-metabolism-in-rats
#10
Guo Liu, Jianyin Miao, Shengwei Sun, Zhen Luo, Zumeng Xia, Baoyan Guo, Fei Liu, Yunjiao Chen, Danyang Ying, Benchun Miao, Yong Cao
The effect of dietary magnesium (Mg) or caseinphosphopeptides (CPPs) on bone metabolism has been reported. However, few studies have investigated the effects of simultaneous supplementation of Mg and CPPs. Sixty-three 3-week-old Sprague-Dawley male rats were divided into seven groups and fed a specified diet for 45 days. Body characteristics, bone physicochemical indicators, and bone metabolism indicators relative to bone metabolism were analyzed. We found that, first, a dietary Mg deficiency resulted in increased bone formation and decreased bone resorption...
November 1, 2017: Food & Function
https://www.readbyqxmd.com/read/29084139/the-impact-of-iodine-status-on-the-recall-rate-of-the-screening-program-for-congenital-hypothyroidism-findings-from-two-national-studies-in-iran
#11
Ladan Mehran, Shahin Yarahmadi, Davood Khalili, Pantea Nazeri, Hossein Delshad, Zahra Abdollahi, Nasrin Azhang, Fereidoun Azizi
Back ground: Iodine deficiency is one of the important factors in increasing the recall rate in congenital hypothyroidism (CH) screening programs. The present study assessed whether the iodine status of the general population may predict the recall rate or vice versa. METHODS: In the current national study, among 1,382,229 live births delivered between March 2010 and March 2011, 1,288,237 neonates were screened for detecting CH by TSH (thyroid stimulating hormone) measurement via heel prick sampling...
October 30, 2017: Nutrients
https://www.readbyqxmd.com/read/29082805/identification-and-prediction-of-the-fertile-window-with-a-new-web-based-medical-device-using-a-vaginal-biosensor-for-measuring-the-circadian-and-circamensual-core-body-temperature
#12
Pedro-Antonio Regidor, Marta Kaczmarczyk, Esther Schiweck, Maren Goeckenjan-Festag, Henry Alexander
Fertility awareness-based (FAB) methods represent a term that includes all family planning methods that are based on the identification of the fertile window. They are based on the woman's observation of physiological signs of the fertile and infertile phases of the menstrual cycle. The first approach consists basically in symptothermal methods accompanied by cervical mucus measurements and clinical menstrual cycling data recording. The second most often used methods are the urinary measurement of E3G and luteinizing hormone (LH) with a personalized computer system...
October 28, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29082109/supporting-the-one-carbon-cycle-restores-ovarian-reserve-in-subfertile-women-absence-of-correlation-with-urinary-bisphenol-a-concentration
#13
Erica Silvestris, Marc Cohen, Dominique Cornet, Laetitia Jacquesson-Fournols, Patrice Clement, Jacques Chouteau, Marc Schneider, Thierry Besnard, Yves Ménézo
Environmental endocrine disrupting chemicals (EDCs), including bisphenol A (BPA), induce DNA methylation errors and oxidative stress, and alter fertility. Animal studies have demonstrated that supporting the one-carbon cycle (1-CC) with appropriate dietary supplements can reduce the effects of EDCs. Anti-Mullerian hormone (AMH), a marker of ovarian functionality, has been tested in subfertile female patients, to control this hypothesis in humans. Fifty-five women with a history of 3-7 years of infertility, with at least two assisted reproductive technology (ART) treatment failures, and low serum levels of AMH were enrolled in the study...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/29078838/cerebral-salt-wasting-syndrome-diagnosis-by-urine-sodium-excretion
#14
Allen I Arieff, Ramin Gabbai, Ira D Goldfine
BACKGROUND: Cerebral salt-wasting syndrome (CSWS) was initially described over 60 years ago in hyponatremic patients with a cerebral lesion. However, the diagnostic criteria for CSWS have not been fully established. Thus, when hyponatremia is observed in patients with CSWS, they may be misdiagnosed as having the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Thus, it is critical to differentiate between these 2 conditions because their treatments are diametrically opposed...
October 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29077874/urinary-cadmium-excretion-is-associated-with-increased-synthesis-of-cortico-and-sex-steroids-in-a-population-study
#15
Murielle Bochud, Judith Jenny-Burri, Menno Pruijm, Belen Ponte, Idris Guessous, Georg Ehret, Dusan Petrovic, Vincent Dudler, Max Haldimann, Geneviève Escher, Bernhard Dick, Markus Mohaupt, Fred Paccaud, Michel Burnier, Antoinette Péchère-Bertschi, Pierre-Yves Martin, Bruno Vogt, Daniel Ackermann
Context: Urinary cadmium (Cd) excretion is associated with cancer and cardiovascular morbidity. A potential intermediate mechanism could be hormone-related by disturbing steroidogenesis in gonads and adrenal glands. Objective: We tested whether urinary Cd and the excretion of metabolites of sex and corticosteroids are correlated in the general adult population. Setting: The Swiss Kidney Project on Genes in Hypertension (SKIPOGH) is a multicentric family-based population study...
October 25, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29074818/randomized-clinical-trial-of-sevelamer-carbonate-on-serum-klotho-and-fibroblast-growth-factor-23-in-ckd
#16
Sophie Liabeuf, Jean-Philippe Ryckelynck, Najeh El Esper, Pablo Ureña, Christian Combe, Bertrand Dussol, Denis Fouque, Philippe Vanhille, Luc Frimat, Eric Thervet, Romuald Mentaverri, Dominique Prié, Gabriel Choukroun
BACKGROUND AND OBJECTIVES: Epidemiologic studies suggest that higher serum phosphaturic hormone fibroblast growth factor 23 levels are associated with increase morbidity and mortality. The aim of the FGF23 Reduction Efficacy of a New Phosphate Binder in CKD Trial was to evaluate the effect of sevelamer carbonate on serum C-terminal fibroblast growth factor 23 levels in normophosphatemic patients with CKD stage 3b/4. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Patients with CKD, eGFR between 45 and 15 ml/min per 1...
October 26, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29072386/-genetic-disorders-of-renal-phosphate-handling
#17
REVIEW
Daniella Magen
Hereditary disorders of renal phosphate handling comprise a diverse group of genetic diseases, usually characterized by excessive urinary phosphate wasting and a negative phosphate balance. In the minority of cases, perturbations of renal phosphate handling are associated with excessive urinary phosphate reabsorption, leading to pathological hyperphosphatemia. Inorganic phosphate is an essential mineral in the human body, playing a crucial role in cellular metabolism and skeletal mineralization. Whole body phosphate balance is maintained by a highly controlled equilibrium between intestinal uptake, skeletal deposition and renal excretion...
October 2017: Harefuah
https://www.readbyqxmd.com/read/29071235/effects-of-thyroid-hormone-on-urinary-concentrating-ability
#18
Elske T Massolt, Mahdi Salih, Carolien M Beukhof, Boen L R Kam, J W Burger, W Edward Visser, Ewout J Hoorn, Robin P Peeters
BACKGROUND: Hypothyroidism has been associated with impaired urinary concentrating ability. However, previous reports on thyroid hormone and urinary concentrating ability in humans only studied a limited number of patients with autoimmune thyroid disease or used healthy controls instead of paired analysis within the same patients. OBJECTIVE: To study the urinary concentrating ability in athyreotic patients with differentiated thyroid cancer on and off levothyroxine treatment as they are exposed to different thyroid states as part of their treatment in the absence of an autoimmune disease...
September 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29067923/effect-of-vitamin-d-therapy-on-urinary-albumin-excretion-renal-functions-and-plasma-renin-among-patients-with-diabetic-nephropathy-a-randomized-double-blind-clinical-trial
#19
Plgc Liyanage, S Lekamwasam, T P Weerarathna, C Liyanage
BACKGROUND: Despite different management strategies, progression of proteinuria occurs in a sizable category of patients with diabetic nephropathy (DN). Increase in serum renin levels induced by the renin-angiotensin system (RAS) may contribute to this. Vitamin D therapy is found to have an inhibitory effect on the RAS. We aimed to study the effects of Vitamin D therapy on renal functions of patients with DN. METHODS: This was a double-blind, randomized, placebo-controlled study...
October 23, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29063209/interrelationship-between-iodine-nutritional-status-of-lactating-mothers-and-their-absolutely-breast-fed-infants-in%C3%A2-coastal%C3%A2-districts-of%C3%A2-gangetic%C3%A2-west-bengal-in-india
#20
N Pal, S K Samanta, A Chakraborty, N K Chandra, A K Chandra
Iodine nutritional status of 128 lactating mothers and their breast-fed infants (1-3 months) from iodine-replete villages during post-salt iodization period was evaluated. Mothers' urine, blood, and breast milk (BM) and infants' urine and blood were collected and analyzed for iodine and serum FT4 and TSH estimation. Mothers' and infants' age, parity, occupation, education, and household income were recorded. Median urinary iodine concentration (UIC) of infants was 250 μg/L, indicating their iodine intake was more than adequate...
October 23, 2017: European Journal of Pediatrics
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