keyword
MENU ▼
Read by QxMD icon Read
search

BFR

keyword
https://www.readbyqxmd.com/read/28230093/pentabromophenol-suppresses-tgf-%C3%AE-signaling-by-accelerating-degradation-of-type-ii-tgf-%C3%AE-receptors-via-caveolae-mediated-endocytosis
#1
Chun-Lin Chen, Pei-Hua Yang, Yu-Chen Kao, Pei-Yu Chen, Chih-Ling Chung, Shih-Wei Wang
Pentabromophenol (PBP), a brominated flame retardant (BFR), is widely used in various consumer products. BFRs exert adverse health effects such as neurotoxic and endocrine-disrupting effects. In this study, we found that PBP suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors. PBP suppressed TGF-β-mediated cell migration, PAI-1 promoter-driven reporter gene activation, and Smad2/3 phosphorylation in various cell types. Furthermore, PBP abolished TGF-β-mediated repression of E-cadherin expression, in addition to the induction of vimentin expression and N-cadherin and fibronectin upregulation, thus blocking TGF-β-induced epithelial-mesenchymal transition in A549 and NMuMG cells...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28224640/low-load-resistance-training-with-low-relative-pressure-produces-muscular-changes-similar-to-high-load-resistance-training
#2
Daeyeol Kim, Jeremy P Loenneke, Xin Ye, Debra A Bemben, Travis W Beck, Rebecca D Larson, Michael G Bemben
INTRODUCTION: The purpose of this study was to compare the acute and chronic response of high-load (HL) resistance training to low-load resistance training with a low blood flow restriction (LL-BFR) pressure. METHODS: Participants completed elbow flexion with either HL or LL-BFR, or non-exercise (CON). In the chronic study, participants in the HL and LL-BFR were trained for 8 weeks to determine differences in muscle size and strength. The acute study examined the changes in Pre/Post torque, muscle swelling, and blood lactate...
February 22, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28219162/-human-exposure-and-thyroid-toxicity-of-polybrominated-diphenyl-ethers
#3
X T Shi, L M Chen, S J Wang, Y Tian
Polybrominated diphenyl ethers (PBDEs), a kind of important Brominated Flame Retardant (BFR), are widely used in electronic products, construction materials and textiles. PBDEs have been detected in many environmental media (including air, water, dust, sediment and food), many animal and human tissues. For their environmental persistence, high bioaccumulative and multiple biotoxicitiies, PBDEs have been viewed as one of the most concerned environmental Endocrine Disrupting Chemicals (EDCs) at present. Although detailed mechanisms are not clear, studies have found that PBDEs can induce toxicity to liver, endocrine system, nervous system, reproduction and immune system...
February 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28214295/blood-flow-restriction-increases-metabolic-stress-but-decreases-muscle-activation-during-high-load-resistance-exercise
#4
Emerson L Teixeira, Renato Barroso, Carla Silva-Batista, Gilberto C Laurentino, Jeremy P Loenneke, Hamilton Roschel, Carlos Ugrinowitsch, Valmor Tricoli
INTRODUCTION: We investigated differences in metabolic stress (lactate) and muscle activation (electromyography) when high load exercise is compared to a condition where blood flow restriction (BFR) is applied during the exercise or during the rest interval. METHODS: Twelve participants performed high load resistance exercise with BFR during the intervals (BFR-I), during the set (BFR-S) and without BFR (HL). Each condition consisted of 3 sets of 8 repetitions with knee-extension at 70% of one-repetition-maximum...
February 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28189029/disruption-of-thyroxine-and-sex-hormones-by-1-2-dibromo-4-1-2-dibromoethyl-cyclohexane-dbe-dbch-in-american-kestrels-falco-sparverius-and-associations-with-reproductive-and-behavioral-changes
#5
Sarah C Marteinson, Vince Palace, Robert J Letcher, Kim J Fernie
1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (DBE-DBCH - formerly TBECH) is an emerging brominated flame retardant (BFR) pollutant with androgen potentiating ability and other endocrine disrupting effects in birds and fish. The objectives of this study were to determine the effects of exposure to environmentally-relevant levels of DBE-DBCH on circulating levels of thyroid and sex steroid hormones in American kestrels, and if hormonal concentrations were related to previously reported changes in reproductive success and courtship behaviors...
February 8, 2017: Environmental Research
https://www.readbyqxmd.com/read/28183863/hemodynamic-responses-are-reduced-with-aerobic-compared-with-resistance-blood-flow-restriction-exercise
#6
Anthony K May, Christopher R Brandner, Stuart A Warmington
The hemodynamics of light-load exercise with an applied blood-flow restriction (BFR) have not been extensively compared between light-intensity, BFR, and high-intensity forms of both resistance and aerobic exercise in the same participant population. Therefore, the purpose of this study was to use a randomized crossover design to examine the hemodynamic responses to resistance and aerobic BFR exercise in comparison with a common high-intensity and light-intensity non-BFR exercise. On separate occasions participants completed a leg-press (resistance) or treadmill (aerobic) trial...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28177216/bacterioferritin-structure-dynamics-and-protein-protein-interactions-at-play-in-iron-storage-and-mobilization
#7
Mario Rivera
Despite its essentiality to life, iron presents significant challenges to cells: the exceedingly low solubility of Fe(3+) limits its bioavailability, and the reactivity of Fe(2+) toward H2O2 is a source of the toxic hydroxyl radical (HO(•)). Consequently, cellular levels of free iron are highly regulated to ensure sufficiency while preventing iron-induced toxicity. Relatively little is known about the fate of iron in the bacterial cytosol or how cells balance the need for relatively high cytosolic iron concentrations with the potential toxicity of the nutrient...
February 8, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28149554/body-mass-index-percent-forced-vital-capacity-respiratory-hospitalization-new-staging-for-idiopathic-pulmonary-fibrosis-patients
#8
Tomoo Kishaba, Hiroaki Nagano, Yuichiro Nei, Shin Yamashiro
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is relentless progressive interstitial lung disease. Evaluating predictor of mortality for IPF patients is crucial. The aim of this study was to evaluate the serial trend of important indicators of prognosis and create a useful staging method for IPF patients. METHODS: We retrospectively searched medical records, pulmonary function tests (PFTs), and chest high resolution computed tomography (HRCT) scans from January 1, 2008 through June 30, 2015 at our hospital...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28149458/cortical-lamina-technique-a-therapeutic-approach-for-lateral-ridge-augmentation-using-guided-bone-regeneration
#9
Shree-Lakshmi Deepika-Penmetsa, Raison Thomas, Tarun-Kumar Baron, Rucha Shah, Dhoom-Singh Mehta
BACKGROUND: The present study aimed at evaluating the efficacy of a novel technique, the bone lamina technique, in horizontal ridge augmentation clinically & radiographically using a combination of allogenic cortical shell, particulate xenograft and resorbable collagen membrane. MATERIAL AND METHODS: Localized horizontal ridge defects, in ten patients (6 male, 4 female), with bucco-palatal ridge width less than 5 mm were included in this study. Localised ridge augmentation was performed using bone lamina technique with mineralised allogenic shell of 1 mm thickness trimmed to the appropriate size using stereo-lithographic models and fixed to the recipient site with stainless steel micro-screws of 1 mm diameter...
January 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28144415/acute-cardiovascular-and-hemodynamic-responses-to-low-intensity-eccentric-resistance-exercise-with-blood-flow-restriction
#10
Behzad Bazgir, Mojtaba Rezazadeh Valojerdi, Hamid Rajabi, Rouhollah Fathi, Seyed Mojtaba Ojaghi, Mohammad Kazem Emami Meybodi, Gabriel R Neto, Mostafa Rahimi, Alireza Asgari
BACKGROUND: Recently it has been suggested that low intensity (LI) resistance exercise (RE) alone or in combination with blood flow restriction (BFR) can be applied for cardiovascular function improvement or rehabilitation. OBJECTIVES: The aim of the present study was to investigate the acute effects of LI eccentric RE with and without BFR on heart rate (HR), rate pressure product (RPP), blood pressure (BP) parameters [systolic, diastolic, and mean arterial pressure (MAP)], oxygen saturation (SpO2) and rate of perceived exertion (RPE)...
December 2016: Asian Journal of Sports Medicine
https://www.readbyqxmd.com/read/28143367/does-a-resistance-exercise-session-with-continuous-or-intermittent-blood-flow-restriction-promote-muscle-damage-and-increase-oxidative-stress
#11
Gabriel R Neto, Jefferson S Novaes, Verônica P Salerno, Michel M Gonçalves, Gilmário R Batista, Maria S Cirilo-Sousa
The aim of this study was to compare the effect of low-load resistance exercise (LLRE) with continuous and intermittent blood flow restriction (BFR) on the creatine kinase (CK), lactate dehydrogenase (LDH), protein carbonyl (PC), thiobarbituric acid-reactive substance (TBARS) and uric acid (UA) levels in military men. The study included 10 recreationally trained men aged 19 ± 0.82 years who underwent the following experimental protocols in random order on separate days (72-96 h): 4 LLRE sessions at a 20% 1RM (one-repetition maximum [1RM]) with continuous BFR (LLRE + CBFR); 4 LLRE sessions at 20% 1RM with intermittent BFR (LLRE + IBFR) and 4 high-intensity resistance exercise (HIRE) sessions at 80% 1RM...
January 31, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28143359/the-role-of-blood-flow-restriction-training-for-applied-practitioners-a-questionnaire-based-survey
#12
Stephen D Patterson, Christopher R Brandner
The purpose of the study was to investigate the current use of blood flow restriction (BFR) by practitioners during exercise/training. A questionnaire was developed and data were obtained from 250 participants, with 115 stating that they had prescribed BFR as an intervention. The most common exercise intervention used in combination with BFR was resistance exercise (99/115), followed by during passive (30/115) conditions, and during aerobic exercise (22/115). The main outcome measure for using the technique was to increase muscle mass (32...
February 1, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28127587/corticospinal-excitability-changes-following-blood-flow-restriction-training-of-the-tibialis-anterior-a-preliminary-study
#13
Erhard Trillingsgaard Næss-Schmidt, Morten Morthorst, Asger Roer Pedersen, Jørgen Feldbæk Nielsen, Peter William Stubbs
AIM: To examine the neural excitability of projections to the tibialis anterior (TA) following blood flow restriction training (BFRT). This is the first study to examine the TA following BFRT. METHODS: Ten subjects performed each experiment. Experiment one consisted of BFRT at 130 mmHg (BFRT-low). Experiment two consisted of BFRT at 200 mmHg (BFRT-high), training (TR-only) and blood flow restriction at 200 mmHg (BFR-only) performed on separate days. Blood flow restriction was applied to the thigh and training consisted of rapid dorsiflexion contractions against gravity every 10 s for 15-min...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28124127/acute-low-intensity-cycling-with-blood-flow-restriction-has-no-effect-on-metabolic-signaling-in-human-skeletal-muscle-compared-to-traditional-exercise
#14
William J Smiles, Miguel S Conceição, Guilherme D Telles, Mara P T Chacon-Mikahil, Cláudia R Cavaglieri, Felipe C Vechin, Cleiton A Libardi, John A Hawley, Donny M Camera
PURPOSE: Autophagy is an intracellular degradative system sensitive to hypoxia and exercise-induced perturbations to cellular bioenergetics. We determined the effects of low-intensity endurance-based exercise performed with blood-flow restriction (BFR) on cell signaling adaptive responses regulating autophagy and substrate metabolism in human skeletal muscle. METHODS: In a randomized cross-over design, nine young, healthy but physically inactive males completed three experimental trials separated by 1 week of recovery consisting of either a resistance exercise bout (REX: 4 × 10 leg press repetitions, 70% 1-RM), endurance exercise (END: 30 min cycling, 70% VO2peak), or low-intensity cycling with BFR (15 min, 40% VO2peak)...
January 25, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28121802/delayed-effect-of-blood-flow-restricted-resistance-training-on-rapid-force-capacity
#15
Jakob Lindberg Nielsen, Ulrik Frandsen, Tatyana Prokhorova, Rune Dueholm Bech, Tobias Nygaard, Charlotte Suetta, Per Aagaard
PURPOSE: The aim of the present study was to investigate the effect and time course of high-frequent low-load resistance training with blood-flow restriction (BFR) on rapid force capacity (i.e. rate of torque development (RTD)). METHODS: Ten male subjects (22.8±2.3 years) performed four sets of knee extensor exercise (20%1RM) to concentric failure during concurrent BFR of the thigh (100mmHg), while eight work-matched controls (21.9±3.0 years) trained without BFR (CON)...
January 23, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28118308/delayed-onset-muscle-soreness-and-perceived-exertion-following-blood-flow-restriction-exercise
#16
Christopher R Brandner, Stuart A Warmington
The purpose of this study was to determine the perceptual responses to resistance exercise with either heavy-loads (80% 1 repetition maximum [1-RM]), light-loads (20% 1-RM), or light-loads in combination with blood flow restriction (BFR). Despite the use of light-loads, it has been suggested that the adoption of BFR resistance exercise may be limited due to increases in delayed onset muscle soreness (DOMS) and perceived exertion. Seventeen healthy untrained males participated in this balanced, randomized cross-over study...
January 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28115972/effects-of-integrated-health-management-intervention-on-overweight-and-obesity
#17
Yiting Yang, Chung Wah Ma, Yide Yang, Xiaoling Wang, Xiaoliang Lin, Lianguo Fu, Shuo Wang, Zhongping Yang, Zhenghe Wang, Xiangkun Meng, Dongmei Ma, Rui Ma, Jun Ma
Overweight or obese adults aged 20~55 years and living in Beijing more than one year were randomly divided into different management groups. A one-year integrated health management intervention was applied in the health management groups. The physical indicators and metabolic indicators changed after one-year intervention on the overweight and obese adults. The annual reduction of the physical indicators was significant in all groups (p < 0.05) except the weight loss in the placebo + general management group...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28099499/oral-microbiota-in-infants-fed-a-formula-supplemented-with-bovine-milk-fat-globule-membranes-a-randomized-controlled-trial
#18
Niklas Timby, Magnus Domellöf, Pernilla Lif Holgerson, Christina E West, Bo Lönnerdal, Olle Hernell, Ingegerd Johansson
BACKGROUND: In a recent study, supplementation of infant formula with milk fat globule membranes (MFGM) decreased the incidence of otitis media in infants <6 months of age. OBJECTIVES: The aim of the present study was to characterize the oral microbiota in infants fed MFGM-supplemented formula and compare it to that of infants fed standard formula or breast milk. METHODS: In a prospective double-blinded randomized controlled trial, exclusively formula-fed infants <2 months of age were randomized to be fed experimental formula (EF, n = 80) with reduced energy and protein and supplemented with a bovine MFGM concentrate, or standard formula (SF, n = 80) until 6 months of age...
2017: PloS One
https://www.readbyqxmd.com/read/28089400/selective-sequential-separation-of-abs-hips-and-pvc-from-automobile-and-electronic-waste-shredder-residue-by-hybrid-nano-fe-ca-cao-assisted-ozonisation-process
#19
Srinivasa Reddy Mallampati, Byoung Ho Lee, Yoshiharu Mitoma, Cristian Simion
The separation of plastics containing brominated flame retardants (BFR) like (acrylonitrile-butadiene-styrene (ABS), high-impact polystyrene (HIPS), and polyvinyl chloride (PVC)) from automobile and electronic waste shredder residue (ASR/ESR) are a major concern for thermal recycling. In laboratory scale tests using a hybrid nano-Fe/Ca/CaO assisted ozonation treatment has been found to selectively hydrophilize the surface of ABS/HIPS and PVC plastics, enhancing ABS wettability and thereby promoting its separation from ASR/ESR by means of froth flotation...
January 12, 2017: Waste Management
https://www.readbyqxmd.com/read/28072883/variability-in-the-effectiveness-of-two-ornithological-survey-methods-between-tropical-forest-ecosystems
#20
Thomas Edward Martin, Josh Nightingale, Jack Baddams, Joseph Monkhouse, Aronika Kaban, Hafiyyan Sastranegara, Yeni Mulyani, George Alan Blackburn, Wilf Simcox
Birds are a frequently chosen group for biodiversity monitoring as they are comparatively straightforward and inexpensive to sample and often perform well as ecological indicators. Two commonly used techniques for monitoring tropical forest bird communities are point counts and mist nets. General strengths and weaknesses of these techniques have been well-defined; however little research has examined how their effectiveness is mediated by the ecology of bird communities and their habitats. We examine how the overall performance of these methodologies differs between two widely separated tropical forests-Cusuco National Park (CNP), a Honduran cloud forest, and the lowland forests of Buton Forest Reserves (BFR) located on Buton Island, Indonesia...
2017: PloS One
keyword
keyword
117434
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"