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https://www.readbyqxmd.com/read/28447134/-poisonings-in-germany-poisons-centres-medical-management-and-national-monitoring
#1
REVIEW
Herbert Desel, Helmut Hentschel, Andreas Stürer
BACKGROUND: Illnesses caused by exposure to extracorporeal artificial substances play a major role in emergency medicine, family medicine, and environmental medicine. OBJECTIVE: The current situation of medical poisoning management and national reporting of poisonings in Germany are described. MATERIALS UND METHODS: The information and data presented here are derived from a literature review and from stakeholder interviews. RESULTS AND CONCLUSION: Eight poison centres (PCs) offer consultation supporting the diagnosis and treatment of poisoning cases in Germany today...
April 26, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28444936/blood-flow-restriction-attenuates-eccentric-exercise-induced-muscle-damage-without-perceptual-and-cardiovascular-overload
#2
Victor M Curty, Alexandre B Melo, Leonardo C Caldas, Lucas Guimarães-Ferreira, Nuno F de Sousa, Paula F Vassallo, Elisardo C Vasquez, Valério G Barauna
The aim of this study was to evaluate the acute effects of high-intensity eccentric exercise (HI-ECC) combined with blood flow restriction (BFR) on muscle damage markers, and perceptual and cardiovascular responses. Nine healthy men (26 ± 1 years, BMI 24 ± 1 kg m(-) ²) underwent unilateral elbow extension in two conditions: without (HI-ECC) and with BFR (HI-ECC+BFR). The HI-ECC protocol corresponded to three sets of 10 repetitions with 130% of maximal strength (1RM). The ratings of perceived exertion (RPE) and pain (RPP) were measured after each set...
April 26, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28441624/various-soil-amendments-and-environmental-wastes-affect-the-im-mobilization-and-phytoavailability-of-potentially-toxic-elements-in-a-sewage-effluent-irrigated-sandy-soil
#3
Sabry M Shaheen, Mohamed S Shams, Mohamed R Khalifa, Mohamed A El-Dali, Jörg Rinklebe
Contamination of long-term sewage effluent irrigated soils by potentially toxic elements (PTEs) is a serious concern due to its high environmental and health risk. Our scientific hypothesis is that soil amendments can cause contradictory effects on the element mobilization and phytoavailability depending on the type of element and amendment. Therefore, we aimed to assess the impact of the application (1%) of several low cost amendments and environmental wastes on the (im)mobilization, availability, and uptake of Al, Cd, Cr, Cu, Fe, Mn, Ni, and Zn by sorghum (Sorghum bicolor) in a long term sewage effluent irrigated sandy soils collected from Egypt...
April 22, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28438281/predictors-of-positive-opinion-about-bach-flower-remedies-in-adults-from-three-latin-american-countries-an-exploratory-study
#4
Boris C Rodríguez-Martín, Melba Fallas-Durán, Barbara Gaitskell, Daniela Vega-Rojas, Paula Martínez-Chaigneau
The current study aimed to determine if positive opinions about BFR interacts with spirituality in adults from three Latin-American countries using a CHAID algorithm. Participants were 703 adults from Cuba (n = 319), Costa Rica (n = 252) and Chile (n = 132). PREDICTORS: demographic data, received information, received treatment, spirituality, dispositional optimism and willingness to use a placebo intervention were measured and analyzed. A supervised classification which included a training phase (n = 423) and a test phase (n = 280) was employed...
May 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28416903/effects-of-strength-training-with-blood-flow-restriction-on-torque-muscle-activation-and-local-muscular-endurance-in-healthy-subjects
#5
Jbc Sousa, G R Neto, H H Santos, J P Araújo, H G Silva, M S Cirilo-Sousa
The present study aimed to analyse the effects of six weeks of strength training (ST), with and without blood flow restriction (BFR), on torque, muscle activation, and local muscular endurance (LME) of the knee extensors. Thirty-seven healthy young individuals were divided into four groups: high intensity (HI), low intensity with BFR (LI+BFR), high intensity and low intensity + BFR (COMB), and low intensity (LI). Torque, muscle activation and LME were evaluated before the test and at the 2(nd), 4(th) and 6(th) weeks after exercise...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28402045/brachial-blood-flow-under-relative-levels-of-blood-flow-restriction-is-decreased-in-a-nonlinear-fashion
#6
J Grant Mouser, Carl J Ade, Christopher D Black, Debra A Bemben, Michael G Bemben
INTRODUCTION: Blood flow restriction (BFR), the application of external pressure to occlude venous return and restrict arterial inflow, has been shown to increase muscular size and strength when combined with low-load resistance exercise. BFR in the research setting uses a wide range of pressures, applying a pressure based upon an individual's systolic pressure or a percentage of occlusion pressure; not a directly determined reduction in blood flow. The relationship between relative pressure and blood flow has not been established...
April 12, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28398660/gestational-and-lactational-exposure-to-an-environmentally-relevant-mixture-of-brominated-flame-retardants-effects-on-neurodevelopment-and-metabolism
#7
Emily W Y Tung, Alice Kawata, Marc Rigden, Wayne J Bowers, Don Caldwell, Alison C Holloway, Bernard Robaire, Barbara F Hales, Michael G Wade
BACKGROUND: Developmental exposure to brominated flame retardants (BFRs), including polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD), has been associated with impaired neurodevelopment and some symptoms of metabolic syndrome. However, there are inconsistencies in studies reporting neurodevelopmental effects with studies of pure substances more likely to report effects than studies of technical products. In addition, the influence of early BFR exposures on later development of metabolic disease-like symptoms has not been investigated...
April 17, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28382443/presence-of-persistent-organic-pollutants-in-a-breeding-common-tern-sterna-hirundo-population-in-ireland
#8
Heidi Acampora, Philip White, Olga Lyashevska, Ian O'Connor
Persistent organic pollutants (POPs) are chemical compounds of environmental concern due to their toxic, persistent nature and their ability to bio-accumulate in biological tissue. Seabirds, for often being at the top of the food web, have been used as monitors of environmental pollutants. Adverse effects caused by POPs have been reported in common terns (Sterna hirundo) since the 1970s. Egg shell thinning, embryo and hatchling deformities have been reported for this species. Environmental legislation, such as the Oslo-Paris Convention (OSPAR), has agreed on the monitoring of concentration of POPs in common terns...
April 5, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28364612/human-exposure-to-hbcd-and-tbbpa-via-indoor-dust-in-korea-estimation-of-external-exposure-and-body-burden
#9
Mandana Barghi, Eun-Su Shin, Jong-Chul Kim, Sung-Deuk Choi, Yoon-Seok Chang
Human exposure to brominated flame retardants (BFRs) such as hexabromocyclododecane (HBCD) and tetrabromobisphenol A (TBBPA) mainly occurs through diet and dust ingestion. In this study, the BFR concentrations in 124 vacuum dust samples of six categories of indoor environments (homes, offices, kindergartens, cars, schools, and public indoor environments) and 32 surface dust samples were investigated. The median ΣHBCD concentrations ranged from 106.30ngg(-1) in home dust to 496.13ngg(-1) in office dust. The TBBPA concentrations in indoor dust (from 78...
March 29, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28363092/vehicles-as-outdoor-bfr-sources-evidence-from-an-investigation-of-bfr-occurrence-in-road-dust
#10
Zhiguo Cao, Leicheng Zhao, Jiangmeng Kuang, Qiaoying Chen, Guifen Zhu, Kunlun Zhang, Shihua Wang, Peipei Wu, Xin Zhang, Xuefeng Wang, Stuart Harrad, Jianhui Sun
The distribution of brominated flame retardants (BFRs) including ∑8PBDEs, DBDPE, BTBPE, EH-TBB, BEH-TEBP and PBEB in road dust (RD) collected in Xinxiang, China was characterized. Analysis of RD samples indicated that the BFR abundance declined as traffic density decreased, with total mean levels of 292, 184, 163, 104 and 70 ng g(-1) dust at sites from traffic intersections, main roads, collector streets, bypasses and parks, respectively. A possible explanation for this phenomenon is that the majority of BFRs may be emitted from the interior of vehicles via their ventilation systems...
July 2017: Chemosphere
https://www.readbyqxmd.com/read/28349628/ferritin-cellular-iron-storage-and-regulation
#11
REVIEW
Paolo Arosio, Leonardo Elia, Maura Poli
Ferritin is considered the major iron storage protein which maintains a large iron core in its cavity and has ferroxidase activity. There are many types of ferritin particularly in prokaryotes that include the canonical 24-mer FTN molecules, the heme-containing BFR, the smaller 12-mer DPS and the newly recognized EncFtn of encapsulin that forms a very large iron storage compartment. Recent studies show that ferritin function is more dynamic than previous depicted and new mechanisms of ferritin iron recycling are emerging...
March 27, 2017: IUBMB Life
https://www.readbyqxmd.com/read/28324168/the-effect-of-eccentric-exercise-with-blood-flow-restriction-on-neuromuscular-activation-microvascular-oxygenation-and-the-repeated-bout-effect
#12
Jakob D Lauver, Trent E Cayot, Timothy Rotarius, Barry W Scheuermann
PURPOSE: To examine the effect of low-intensity eccentric contractions with and without blood flow restriction (BFR) on microvascular oxygenation, neuromuscular activation, and the repeated bout effect (RBE). METHODS: Participants were randomly assigned to either low-intensity (LI), low-intensity with BFR (LI-BFR), or a control (CON) group. Participants in LI and LI-BFR performed a preconditioning bout of low-intensity eccentric exercise prior to about of maximal eccentric exercise...
March 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28319741/influence-of-sampling-approach-on-concentrations-of-legacy-and-novel-brominated-flame-retardants-in-indoor-dust
#13
Layla Salih Al-Omran, Stuart Harrad
The study investigates the impact of sampling method on the concentrations of PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, and BDE-209) and NBFRs (PBEB, EH-TBB, BEH-TEBP, BTBPE and DBDPE) in indoor dust. A total of 36 dust samples were collected from 12 homes in Birmingham, UK (3 samples per home comprising researcher collected dust - both RCD from the living room (RCDL) and bedroom (RCDB), with an additional householder vacuum dust sample - HHVD). BDE-209 was the predominant compound, with average concentrations of 2642, 2336 and 2634 ng/g in RCDL, RCDB and HHVD respectively...
February 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/28318006/inhibiting-the-bfrb-bfd-interaction-in-pseudomonas-aeruginosa-causes-irreversible-iron-accumulation-in-bacterioferritin-and-iron-deficiency-in-the-bacterial-cytosol
#14
Kate Eshelman, Huili Yao, Achala N D Punchi Hewage, Jacqueline J Deay, Josephine R Chandler, Mario Rivera
Iron is an essential nutrient for bacteria but the reactivity of Fe(2+) and the insolubility of Fe(3+) present significant challenges to bacterial cells. Iron storage proteins contribute to ameliorating these challenges by oxidizing Fe(2+) using O2 and H2O2 as electron acceptors, and by compartmentalizing Fe(3+). Two types of iron-storage proteins coexist in bacteria, the ferritins (Ftn) and the heme-containing bacterioferritins (Bfr), but the reasons for their coexistence are largely unknown. P. aeruginosa cells harbor two iron storage proteins (FtnA and BfrB), but nothing is known about their relative contributions to iron homeostasis...
March 20, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28297069/is-early-cannulation-of-an-arteriovenous-fistula-associated-with-early-failure-of-the-fistula
#15
Teun Wilmink, Lee Hollingworth, Tamasin Stevenson, Sarah Powers
OBJECTIVE: To study the effect of early cannulation of arteriovenous fistulas (AVF) on early AVF failure. METHODS: Analysis of two databases of access operations and dialysis sessions from 1/12/2002 till 1/4/2015. Follow-up until 1/4/2016. Functional dialysis use defined as six consecutive cannulations of the AVF with two needles. Early cannulation defined as needling of the AVF within 30 days of creation. Early failure was defined as abandonment for new form of access within 90 days of first cannulation...
March 6, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28259850/blood-flow-restriction-training-in-clinical-musculoskeletal-rehabilitation-a-systematic-review-and-meta-analysis
#16
REVIEW
Luke Hughes, Bruce Paton, Ben Rosenblatt, Conor Gissane, Stephen David Patterson
BACKGROUND AND OBJECTIVE: Low-load exercise training with blood flow restriction (BFR) can increase muscle strength and may offer an effective clinical musculoskeletal (MSK) rehabilitation tool. The aim of this review was to systematically analyse the evidence regarding the effectiveness of this novel training modality in clinical MSK rehabilitation. DESIGN: This is a systematic review and meta-analysis of peer-reviewed literature examining BFR training in clinical MSK rehabilitation (Research Registry; researchregistry91)...
March 4, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28251784/the-acute-muscular-response-to-blood-flow-restricted-exercise-with-very-low-relative-pressure
#17
Matthew B Jessee, Kevin T Mattocks, Samuel L Buckner, J Grant Mouser, Brittany R Counts, Scott J Dankel, Gilberto C Laurentino, Jeremy P Loenneke
To investigate the acute responses to blood flow-restricted (BFR) exercise across low, moderate and high relative pressures. Muscle thickness, maximal voluntary contraction (MVC) and electromyography (EMG) amplitude were assessed following exercise with six different BFR pressures: 0%, 10%, 20%, 30%, 50% and 90% of arterial occlusion pressure (AOP). There were differences between each time point within each condition for muscle thickness, which increased postexercise [+0·47 (0·40, 0·54) cm] and then trended towards baseline...
March 2, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28245009/-tetrabromobisphenol-a-toxicity-environmental-and-occupational-exposures
#18
REVIEW
Monika Jarosiewicz, Bożena Bukowska
Brominated flame retardants (BFR), including tetrabromobisphenol A (TBBPA) represents 25% of the global market of flame retardants. Among them, TBBPA is used on the largest scale (approx. 60%) because of its firebreak properties and widespread occurrence in every day products such as furniture, upholstery, adhesives and electronic equipment. A broad application of TBBPA can contribute to environmental pollution. Tetrabromobisphenol A has been determined in soil, water, river sediments and the atmosphere. Tetrabromobisphenol A is characterized by a high value of coefficient n-octanol/water (log P = 4...
February 28, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28230093/pentabromophenol-suppresses-tgf-%C3%AE-signaling-by-accelerating-degradation-of-type-ii-tgf-%C3%AE-receptors-via-caveolae-mediated-endocytosis
#19
Chun-Lin Chen, Pei-Hua Yang, Yu-Chen Kao, Pei-Yu Chen, Chih-Ling Chung, Shih-Wei Wang
Pentabromophenol (PBP), a brominated flame retardant (BFR), is widely used in various consumer products. BFRs exert adverse health effects such as neurotoxic and endocrine-disrupting effects. In this study, we found that PBP suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors. PBP suppressed TGF-β-mediated cell migration, PAI-1 promoter-driven reporter gene activation, and Smad2/3 phosphorylation in various cell types. Furthermore, PBP abolished TGF-β-mediated repression of E-cadherin expression, in addition to the induction of vimentin expression and N-cadherin and fibronectin upregulation, thus blocking TGF-β-induced epithelial-mesenchymal transition in A549 and NMuMG cells...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28224640/low-load-resistance-training-with-low-relative-pressure-produces-muscular-changes-similar-to-high-load-resistance-training
#20
Daeyeol Kim, Jeremy P Loenneke, Xin Ye, Debra A Bemben, Travis W Beck, Rebecca D Larson, Michael G Bemben
INTRODUCTION: This study compares the acute and chronic response of high-load resistance training (HL) to low-load resistance training with low blood flow restriction (LL-BFR) pressure. METHODS: Participants completed elbow flexion with either HL or LL-BFR or nonexercise. In the chronic study, participants in the HL and LL-BFR groups were trained for 8 weeks to determine differences in muscle size and strength. The acute study examined the changes in pretesting/posttesting (Pre/Post) torque, muscle swelling, and blood lactate...
February 22, 2017: Muscle & Nerve
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