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https://www.readbyqxmd.com/read/28099499/oral-microbiota-in-infants-fed-a-formula-supplemented-with-bovine-milk-fat-globule-membranes-a-randomized-controlled-trial
#1
Niklas Timby, Magnus Domellöf, Pernilla Lif Holgerson, Christina E West, Bo Lönnerdal, Olle Hernell, Ingegerd Johansson
BACKGROUND: In a recent study, supplementation of infant formula with milk fat globule membranes (MFGM) decreased the incidence of otitis media in infants <6 months of age. OBJECTIVES: The aim of the present study was to characterize the oral microbiota in infants fed MFGM-supplemented formula and compare it to that of infants fed standard formula or breast milk. METHODS: In a prospective double-blinded randomized controlled trial, exclusively formula-fed infants <2 months of age were randomized to be fed experimental formula (EF, n = 80) with reduced energy and protein and supplemented with a bovine MFGM concentrate, or standard formula (SF, n = 80) until 6 months of age...
2017: PloS One
https://www.readbyqxmd.com/read/28089400/selective-sequential-separation-of-abs-hips-and-pvc-from-automobile-and-electronic-waste-shredder-residue-by-hybrid-nano-fe-ca-cao-assisted-ozonisation-process
#2
Srinivasa Reddy Mallampati, Byoung Ho Lee, Yoshiharu Mitoma, Cristian Simion
The separation of plastics containing brominated flame retardants (BFR) like (acrylonitrile-butadiene-styrene (ABS), high-impact polystyrene (HIPS), and polyvinyl chloride (PVC)) from automobile and electronic waste shredder residue (ASR/ESR) are a major concern for thermal recycling. In laboratory scale tests using a hybrid nano-Fe/Ca/CaO assisted ozonation treatment has been found to selectively hydrophilize the surface of ABS/HIPS and PVC plastics, enhancing ABS wettability and thereby promoting its separation from ASR/ESR by means of froth flotation...
January 12, 2017: Waste Management
https://www.readbyqxmd.com/read/28072883/variability-in-the-effectiveness-of-two-ornithological-survey-methods-between-tropical-forest-ecosystems
#3
Thomas Edward Martin, Josh Nightingale, Jack Baddams, Joseph Monkhouse, Aronika Kaban, Hafiyyan Sastranegara, Yeni Mulyani, George Alan Blackburn, Wilf Simcox
Birds are a frequently chosen group for biodiversity monitoring as they are comparatively straightforward and inexpensive to sample and often perform well as ecological indicators. Two commonly used techniques for monitoring tropical forest bird communities are point counts and mist nets. General strengths and weaknesses of these techniques have been well-defined; however little research has examined how their effectiveness is mediated by the ecology of bird communities and their habitats. We examine how the overall performance of these methodologies differs between two widely separated tropical forests-Cusuco National Park (CNP), a Honduran cloud forest, and the lowland forests of Buton Forest Reserves (BFR) located on Buton Island, Indonesia...
2017: PloS One
https://www.readbyqxmd.com/read/28067429/lnk-deficiency-leads-to-tpo-mediated-osteoclastogenesis-and-increased-bone-mass-phenotype
#4
David J Olivos, Marta Alvarez, Ying-Hua Cheng, R Adam Hooker, Wendy A Ciovacco, Monique Bethel, Haley McGough, Christopher Yim, Brahmananda R Chitteti, Pierre P Eleniste, Mark C Horowitz, Edward F Srour, Angela Bruzzaniti, Robyn K Fuchs, Melissa A Kacena
The Lnk adapter protein negatively regulates the signaling of thrombopoietin (TPO), the main megakaryocyte (MK) growth factor. Lnk-deficient (-/-) mice have increased TPO signaling and increased MK number. Interestingly, several mouse models exist in which increased MK number leads to a high bone mass phenotype. Here we report the bone phenotype of these mice. MicroCT and static histomorphometric analyses at 20 weeks showed the distal femur of Lnk(-/-) mice to have significantly higher bone volume fraction and trabecular number compared to wild-type (WT) mice...
January 9, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28060867/differential-roles-of-iron-storage-proteins-in-maintaining-the-iron-homeostasis-in-mycobacterium-tuberculosis
#5
Garima Khare, Prachi Nangpal, Anil K Tyagi
Ferritins and bacterioferritins are iron storage proteins that represent key players in iron homeostasis. Several organisms possess both forms of ferritins, however, their relative physiological roles are less understood. Mycobacterium tuberculosis possesses both ferritin (BfrB) and bacterioferritin (BfrA), playing an essential role in its pathogenesis as reported by us earlier. This study provides insights into the role of these two proteins in iron homeostasis by employing M. tuberculosis bfr mutants. Our data suggests that BfrA is required for efficient utilization of stored iron under low iron conditions while BfrB plays a crucial role as the major defense protein under excessive iron conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28058460/-risk-assessment-of-synephrine-in-dietary-supplements
#6
Nadiya Bakhyia, Birgit Dusemund, Klaus Richter, Oliver Lindtner, Karen Ildico Hirsch-Ernst, Bernd Schäfer, Alfonso Lampen
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. It is often added to dietary supplements intended for weight loss and enhancement of sports performance, typically in the form of Citrus aurantium extracts and in many cases in combination with caffeine. The health risks of synephrine were evaluated on the basis of the available toxicological data and in accordance to the EFSA guidance on the safety assessment of botanicals and botanical preparations intended for use in food supplements...
January 5, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28029066/cardiac-autonomic-and-haemodynamic-recovery-after-a-single-session-of-aerobic-exercise-with-and-without-blood-flow-restriction-in-older-adults
#7
Marina Lívia Venturini Ferreira, Amanda Veiga Sardeli, Giovana Vergínia De Souza, Valéria Bonganha, Lucas Do Carmo Santos, Alex Castro, Cláudia Regina Cavaglieri, Mara Patrícia Traina Chacon-Mikahil
This study investigated the autonomic and haemodynamic responses to different aerobic exercise loads, with and without blood flow restriction (BFR). In a crossover study, 21 older adults (8 males and 13 females) completed different aerobic exercise sessions: low load without BFR (LL) (40% VO2max), low load with BFR (LL-BFR) (40% VO2max + 50% BFR) and high load without BFR (HL) (70% VO2max). Heart rate variability and haemodynamic responses were recorded during rest and throughout 30 min of recovery. HL reduced R-R interval, the root mean square of successive difference of R-R intervals and high frequency during 30 min of recovery at a greater magnitude compared with LL and LL-BFR...
December 28, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28024741/characterization-of-pbdes-and-novel-brominated-flame-retardants-in-seawater-near-a-coastal-mariculture-area-of-the-bohai-sea-china
#8
Yan Wang, Xiaowei Wu, Hongxia Zhao, Qing Xie, Minmin Hou, Qiaonan Zhang, Juan Du, Jingwen Chen
The concentrations and distributions of PBDEs and novel brominated flame retardants (NBFRs) in dissolved phase of surface seawater near a coastal mariculture area of the Bohai Sea were investigated. The total concentrations of PBDE and NBFRs were in the range of 15.4-65.5 and 2.12-13.6ng/L, respectively. The highest concentration was discovered in the water near an anchorage ground, whereas concentrations in water samples from offshore cage-culture area were not elevated. Relatively high concentrations of BDE28, 99, and 100 were discovered in the medium range of distance from shore, where is the path of tidal or coastal current...
December 23, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28013361/bone-mass-and-strength-are-significantly-improved-in-mice-overexpressing-human-wnt16-in-osteocytes
#9
Imranul Alam, Austin M Reilly, Mohammed Alkhouli, Rita L Gerard-O'Riley, Charishma Kasipathi, Dana K Oakes, Weston B Wright, Dena Acton, Amie K McQueen, Bhavmik Patel, Kyung-Eun Lim, Alexander G Robling, Michael J Econs
Recently, we demonstrated that osteoblast-specific overexpression of human WNT16 increased both cortical and trabecular bone mass and structure in mice. To further identify the cell-specific role of Wnt16 in bone homeostasis, we created transgenic (TG) mice overexpressing human WNT16 in osteocytes using Dmp1 promoter (Dmp1-hWNT16 TG) on C57BL/6 (B6) background. We analyzed bone phenotypes and serum bone biomarkers, performed gene expression analysis and measured dynamic bone histomorphometry in Dmp1-hWNT16 TG and wild-type (WT) mice...
December 24, 2016: Calcified Tissue International
https://www.readbyqxmd.com/read/28002685/effects-of-blood-flow-restriction-on-biomarkers-of-myogenesis-in-response-to-resistance-exercise
#10
Andrew S Layne, Kelly Larkin-Kaiser, R Gavin MacNeil, Marvin Dirain, Bhanuprasad Sandesara, Todd M Manini, Thomas W Buford
We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was significantly higher following CNTRL...
January 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27993048/kinetics-of-brominated-flame-retardant-bfr-releases-from-granules-of-waste-plastics
#11
Bingbing Sun, Yuanan Hu, Hefa Cheng, Shu Tao
Plastic components of e-waste contain high levels of brominated flame retardants (BFRs), whose releases cause environmental and human health concerns. This study characterized the release kinetics of polybrominated diphenyl ethers (PBDEs) from millimeter-sized granules processed from the plastic exteriors of two scrap computer displays at environmentally relevant temperatures. The release rate of a substitute of PBDEs, 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), from the waste plastics, was reported for the first time...
December 20, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27991478/hemodialysis-delivery-dialysis-dose-achievement-and-vascular-access-types-in-hemodialysis-patients-from-the-gulf-cooperation-council-countries-enrolled-in-the-dialysis-outcomes-and-practice-patterns-study-phase-5-2012-2015
#12
Anas AlYousef, Sumaya AlGhareeb, Jamal Al Wakeel, Saeed M G Al-Ghamdi, Brian A Bieber, Mohamad Hassan, Yacoub Al Maimani, Naser Alkandari, Haroun Z Ahmed, Ashraf Fawzy, Ronald L Pisoni
The prospective observational Dialysis Outcomes and Practice Patterns Study (DOPPS) was initiated in late 2012 in national samples of hemodialysis (HD) units (n = 41 study sites) in all six Gulf Cooperation Council (GCC) countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates). For many years, guidelines have recommended single pool Kt/V ≥1.2 as the minimum adequate dose for chronic HD patients. Here, we report initial DOPPS results regarding HD practices related to dialysis dose achievement in the GCC...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27939957/time-course-of-disassociation-of-bone-formation-signals-with-bone-mass-and-bone-strength-in-sclerostin-antibody-treated-ovariectomized-rats
#13
Yanfei L Ma, Matthew Hamang, Jonathan Lucchesi, Nicoletta Bivi, Qianqiang Zeng, Mary D Adrian, Sarah E Raines, Jiliang Li, Stuart A Kuhstoss, Victor Obungu, Henry U Bryant, Venkatesh Krishnan
Sclerostin antibodies increase bone mass by stimulating bone formation. However, human and animal studies show that bone formation increases transiently and returns to pre-treatment level despite ongoing antibody treatment. To understand its mechanism of action, we studied the time course of bone formation, correlating the rate and extent of accrual of bone mass and strength after sclerostin antibody treatment. Ovariectomized (OVX) rats were treated with a sclerostin-antibody (Scle-ab) at 20mg/kg sc once weekly and sacrificed at baseline and 2, 3, 4, 6, and 8weeks post-treatment...
December 8, 2016: Bone
https://www.readbyqxmd.com/read/27931053/hemodynamic-responses-to-blood-flow-restriction-and-resistance-exercise-to-muscular-failure
#14
C A Libardi, A M Catai, M Miquelini, A Borghi-Silva, V Minatel, I F Alvarez, J C Milan-Mattos, H Roschel, V Tricoli, C Ugrinowitsch
The aim of the present study was to compare hemodynamic responses between blood flow-restricted resistance exercise (BFR-RE), high-intensity resistance exercise (HI-RE) and low-intensity resistance exercise (LI-RE) performed to muscular failure. 12 men (age: 20±3 years; body mass: 73.5±9 kg; height: 174±6 cm) performed 4 sets of leg press exercises using BFR-RE (30% of 1-RM), HI-RE (80% of 1-RM) and LI-RE (30% of 1-RM) protocols. Systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (CO) and total peripheral vascular resistance (TPR) were measured on a beat-to-beat continuous basis by a noninvasive photoplethysmographic arterial pressure device...
December 8, 2016: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27905993/pregnant-women-s-perceptions-of-exposure-to-brominated-flame-retardants
#15
A Lane, C G Goodyer, F Rab, J M Ashley, S Sharma, A Hodgson, J Nisker
BACKGROUND: Recent media reports on human studies associating brominated flame retardants (BFRs) in household products in pregnancy with urogenital anomalies in boys and endocrine disruption in both sexes. We sought to explore the perceptions of pregnant women of brominated flame retardant (BFR) exposure, in light of recent media reports on the adverse health effects of BFR exposure prenatally. METHODS: Pregnant women were recruited for interviews through posters and pamphlets in prenatal clinics, prenatal fairs and community centres...
December 1, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27884470/the-first-exposure-assessment-of-legacy-and-unrestricted-brominated-flame-retardants-in-predatory-birds-of-pakistan
#16
Naeem Akhtar Abbasi, Igor Eulaers, Veerle Leontina Bernard Jaspers, Muhammad Jamshed Iqbal Chaudhry, Adrien Frantz, Per Lennart Ambus, Adrian Covaci, Riffat Naseem Malik
The exposure to legacy polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDDs) and unrestricted 1,2-bis (2,4,6-tribromophenoxy) ethane (BTBPE), bis (2-ethylhexyl)-2,3,4,5-tetrabromophthalate (BEH-TEBP) and 2-ethylhexyl-2,3,4,5-tetrabromo-benzoate (EH-TBB) was examined in tail feathers of 76 birds belonging to ten predatory species inhabiting Pakistan. In addition, different feather types of six individuals of Black kite (Milvus migrans) were compared for their brominated flame retardant (BFR) levels...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27837041/acute-effects-of-resistance-exercise-with-continuous-and-intermittent-blood-flow-restriction-on-hemodynamic-measurements-and-perceived-exertion
#17
Gabriel R Neto, Jefferson S Novaes, Verônica P Salerno, Michel M Gonçalves, Bruna K L Piazera, Thais Rodrigues-Rodrigues, Maria S Cirilo-Sousa
This study compared the acute effects of low-intensity resistance exercise (RE) sessions for the upper limb with continuous and intermittent blood flow restriction (BFR) and high-intensity RE with no BFR on lactate, heart rate, double product (DP; heart rate times systolic blood pressure), and perceived exertion (RPE). Ten recreationally trained men (1-5 years strength training; age mean = 19 ± 0.82 years) performed three experimental protocols in random order: (a) low-intensity RE at 20% one-repetition maximum (1RM) with intermittent BFR (LI + IBFR), (b) low-intensity RE at 20% 1RM with continuous BFR (LI + CBFR), and (c) high-intensity RE at 80% 1RM...
November 11, 2016: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/27833648/alternative-drugs-go-global-possible-lead-and-or-mercury-intoxication-from-imported-natural-health-products-and-a-need-for-scientifically-evaluated-poisoning-monitoring-from-environmental-exposures
#18
Lygia Therese Budnik, Xaver Baur, Volker Harth, Axel Hahn
BACKGROUND: With increases in globalization, cultural remedies from Chinese, Ayurvedic, Arab and other traditions have become more available to international consumers, offering unfamiliar "Natural Health Products" (NHP), used as alternative medicine or supplementary medicine. Contamination with toxic ingredients including lead, mercury, arsenic, and other toxic elements has been documented in several of these products from various parts of the globe, particularly from some parts of Asia and the Orient...
2016: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/27826654/physiological-responses-to-interval-endurance-exercise-at-different-levels-of-blood-flow-restriction
#19
Rogério B Corvino, Harry B Rossiter, Thiago Loch, Jéssica C Martins, Fabrizio Caputo
PURPOSE: We aimed to identify a blood flow restriction (BFR) endurance exercise protocol that would both maximize cardiopulmonary and metabolic strain, and minimize the perception of effort. METHODS: Twelve healthy males (23 ± 2 years, 75 ± 7 kg) performed five different exercise protocols in randomized order: HI, high-intensity exercise starting at 105% of the incremental peak power (P peak); I-BFR30, intermittent BFR at 30% P peak; C-BFR30, continuous BFR at 30% P peak; CON30, control exercise without BFR at 30% P peak; I-BFR0, intermittent BFR during unloaded exercise...
November 8, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27796050/inflammatory-bowel-disease-in-a-rodent-model-alters-osteocyte-protein-levels-controlling-bone-turnover
#20
Corinne E Metzger, A Narayanan, D C Zawieja, S A Bloomfield
Bone loss is a common comorbidity of inflammatory bowel disease (IBD), leading to elevated fracture risk in these patients. Inflammatory factors associated with IBD cause increased bone resorption and decreased bone formation with multiple factors implicated as instigators of these alterations. In this project, we examined the influence of IBD on osteocytes proteins in male rats (2 months old) divided into two groups: induced gut inflammation via TNBS enema and vehicle control. We examined the prevalence of two pro-inflammatory cytokines, tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), an anti-inflammatory cytokine, interleukin-10 (IL-10), the anabolic factor insulin-like growth factor-I (IGF-I), osteoclastogenesis regulators RANKL and OPG, and the bone formation inhibitor sclerostin in osteocytes in three bone compartments 4 weeks after initiation of gut inflammation...
October 31, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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