keyword
MENU ▼
Read by QxMD icon Read
search

BFR

keyword
https://www.readbyqxmd.com/read/29350278/lower-body-blood-flow-restriction-training-may-induce-remote-muscle-strength-adaptations-in-an-active-unrestricted-arm
#1
Anthony K May, Aaron P Russell, Stuart A Warmington
PURPOSE: We examined the concurrent characteristics of the remote development of strength and cross-sectional area (CSA) of upper body skeletal muscle in response to lower body resistance training performed with an applied blood flow restriction (BFR). METHODS: Males allocated to an experimental BFR group (EXP; n = 12) or a non-BFR control group (CON; n = 12) completed 7-weeks of resistance training comprising three sets of unilateral bicep curls [50% 1-repetition maximum (1-RM)], then four sets of bilateral knee extension and flexion exercises (30% 1-RM)...
January 19, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29349721/effects-of-load-on-the-acute-response-of-muscles-proximal-and-distal-to-blood-flow-restriction
#2
Matthew B Jessee, J Grant Mouser, Samuel L Buckner, Scott J Dankel, Kevin T Mattocks, Takashi Abe, Jeremy P Loenneke
To determine the effects of load and blood flow restriction (BFR) on muscular responses, we asked 12 participants to perform chest presses under four different conditions [30/0, 30/40, 50/0, and 50/40, presented as percentage one-repetition maximum (1RM)/percentage arterial occlusion pressure (AOP)]. Muscle thickness increased pre- to post-exercise [chest: mean 0.29, 95% confidence interval (CI) 0.21, 0.37 cm; triceps: mean 0.44, 95% CI 0.34, 0.54 cm], remaining elevated for 15 min post-exercise. Electromyography amplitude was greater with 50% 1RM and increased over time for the first three repetitions of each set of chest presses...
January 18, 2018: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29343183/the-acute-angiogenic-signalling-response-to-low-load-resistance-exercise-with-blood-flow-restriction
#3
Richard A Ferguson, Julie E A Hunt, Mark P Lewis, Neil R W Martin, Darren J Player, Carolin Stangier, Conor W Taylor, Mark C Turner
This study investigated protein kinase activation and gene expression of angiogenic factors in response to low-load resistance exercise with or without blood flow restriction (BFR). In a repeated measures cross-over design, six males performed four sets of bilateral knee extension exercise at 20% 1RM (reps per set = 30:15:15:continued to fatigue) with BFR (110 mmHg) and without (CON). Muscle biopsies were obtained from the vastus lateralis before, 2 and 4 h post-exercise. mRNA expression was determined using real-time RT-PCR...
January 17, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29331935/disruption-of-thyroid-hormone-sulfotransferase-activity-by-brominated-flame-retardant-chemicals-in-the-human-choriocarcinoma-placenta-cell-line-bewo
#4
Christopher P Leonetti, Craig M Butt, Heather M Stapleton
Brominated flame retardants (BFRs) have been shown to disrupt thyroid hormone (TH) homeostasis through multiple mechanisms, including inhibition of enzymes that regulate intracellular levels of THs, such as sulfotransferases (SULTs). The placenta plays a critical role in helping to maintain TH levels during fetal development and expresses SULTs. This is concerning given that disruption of TH regulation within the placenta could potentially harm the developing fetus. In this study, we investigated the effects of two polybrominated diphenyl ethers (PBDEs), two hydroxylated PBDEs, and 2,4,6-tribromophenol (2,4,6-TBP) on TH SULT activity in a choriocarcinoma placenta cell line (BeWo)...
December 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/29317069/blood-flow-restriction-training-as-a-prehabilitation-concept-in-total-knee-arthroplasty-a-narrative-review-about-current-preoperative-interventions-and-the-potential-impact-of-bfr
#5
Alexander Franz, Fina Pauline Queitsch, Michael Behringer, Constantin Mayer, Rüdiger Krauspe, Christoph Zilkens
Osteoarthritis of the knee is one of the most commonly diagnosed joint ailments and responsible for increased rates of total knee arthroplasty surgeries worldwide. Whereas the surgical approach is able to diminish the perceived knee pain of concerned patients', the postoperative recovery is often accompanied by persistent skeletal muscle dysfunctions and atrophy, which is responsible for functional deficits for up to several years. Recent findings indicate that surgery induced adverse effects on skeletal muscles are largely associated with the use of pneumatic tourniquets, wherefore several studies try to reduce tourniquet use in orthopedic surgery...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29274584/the-protective-effects-of-triptolide-on-age-related-bone-loss-in-old-male-rats
#6
Deqing Luo, Hongyue Ren, Huantang Zhang, Peng Zhang, Zunxian Huang, Hang Xian, Kejian Lian, Dasheng Lin
BACKGROUND: Previous studies have showed that triptolide have a critical role in inhibiting osteoclast formation, bone resorption and attenuating regional osteoporosis. However, the protective role of triptolide on age-related bone loss has not been investigated. In the study, we assessed the effect of triptolide supplementation on bone microstructure and bone remolding in old male rat lumbars. METHODS: Fifty-two 22-month-old male Sprague-Dawley rats were randomly assigned to either triptolide treatment group or control group...
December 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29236134/determination-of-halogenated-flame-retardants-by-gc-api-ms-ms-and-gc-ei-ms-a-multi-compound-multi-matrix-method
#7
Frank Neugebauer, Annekatrin Dreyer, Nina Lohmann, Jan Koschorreck
The extensive application of halogenated flame retardants has led to their widespread distribution in the environment. Recently, concerns emerged regarding their potential persistence, (bio)accumulation, and/or toxicity. Particularly halogenated flame retardants based on norbornene structures, like Dechlorane Plus as well as other brominated PBDE replacements, generically called emerging, novel, or alternative flame retardants, are in the focus of interest. A comprehensive analytical method for the determination of 21 halogenated flame retardants (HFRs) of different substance classes (dechloranes, brominated aromates, brominated ethers, cyclic BFR) in a broad variety of matrices (tree leaves, fish fillet, birds eggs, suspended particles) was developed in order to assess their environmental levels as well as temporal trends, especially for the use within environmental specimen banks (ESBs)...
December 13, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29234504/the-effects-of-low-intensity-blood-flow-restricted-exercise-compared-with-conventional-resistance-training-on-the-clinical-outcomes-of-active-uk-military-personnel-following-a-3-week-in-patient-rehabilitation-programme-protocol-for-a-randomized-controlled-feasibility
#8
Peter Ladlow, Russell J Coppack, Shreshth Dharm-Datta, Dean Conway, Edward Sellon, Stephen D Patterson, Alexander N Bennett
Background: A challenge for rehabilitation practitioners lies in designing optimal exercise programmes that facilitate musculoskeletal (MSK) adaptations whilst simultaneously accommodating biological healing and the safe loading of an injured limb. A growing body of evidence supports the use of resistance training at a reduced load in combination with blood flow restriction (BFR) to enhance hypertrophic and strength responses in skeletal muscle. In-patient rehabilitation has a long tradition in the UK Military, however, the efficacy of low intensity (LI) BFR training has not been tested in this rehabilitation setting...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29228439/beneficial-effects-of-low-level-laser-irradiation-on-senile-osteoporosis-in-rats
#9
C-T Zhu, T Li, P Zhang, M Zou, Q Guo, X-W Qu
OBJECTIVE: To investigate the effect of low-level laser irradiation (LLLI) on bone mineral density (BMD), bone structures, bone biomechanical properties and bone metabolism in senile osteoporosis, and to explore a relatively more secure and effective way to prevent and treat osteoporosis. MATERIALS AND METHODS: Sprague-Dawley (SD) male rats at different age stages (4 months old, 12 months old and 20 months old) were selected and randomly divided into six groups...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29219744/n-nitrosamines-migrating-from-food-contact-materials-into-food-simulants-analysis-and-quantification-by-means-of-hplc-apci-ms-ms
#10
Friederike Kühne, Oliver Kappenstein, Samira Straβgütl, Florian Weese, Jürgen Weyer, Karla Pfaff, Andreas Luch
It was the aim of the work described here to develop a validated analytical method for the determination N-nitrosamines in food simulants. Here, we present the validation of a liquid chromatography-atmospheric pressure chemical ionisation-tandem mass spectrometry (LC-APCI-MS/MS) method for the determination of thirteen N-nitrosamines in the food simulants deionised water, 3 % acetic acid and 10 % ethanol. Method validation encompassed linearity, limit of detection (LOD), limit of quantification (LOQ), recovery, precision and stability of the N-nitrosamines...
December 8, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29192767/a-trojan-horse-for-light-triggered-bifurcated-production-of-singlet-oxygen-and-fenton-reactive-iron-within-cancer-cells
#11
Daniela Cioloboc, Christopher Kennedy, Emily N Boice, Emily R Clark, Donald M Kurtz
Traditional photodynamic therapy for cancer relies on dye-photosensitized generation of singlet oxygen. However, therapeutically effective singlet oxygen generation requires well-oxygenated tissues, whereas many tumor environments tend to be hypoxic. We describe a platform for targeted enhancement of photodynamic therapy that produces singlet oxygen in oxygenated environments and hydroxyl radical, which is typically regarded as the most toxic reactive oxygen species, in hypoxic environments. The 24-subunit iron storage protein bacterioferritin (Bfr) has the unique property of binding 12 heme groups in its protein shell...
December 1, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/29184265/long-term-low-intensity-endurance-exercise-along-with-blood-flow-restriction-improves-muscle-mass-and-neuromuscular-junction-compartments-in-old-rats
#12
Mohammad-Ali Bahreini Pour, Siyavash Joukar, Fariborz Hovanloo, Hamid Najafipour
Background: During the aging process, muscle atrophy and neuromuscular junction remodeling are inevitable. The present study aimed to clarify whether low-intensity aerobic exercise along with limb blood-flow restriction (BFR) could improve aging-induced muscle atrophy and nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. Methods: Forty-eight male Wistar rats, aged 23-24 months, were randomly divided into control, sham (Sh: subjected to surgery without BFR), BFR (subjected to BFR), exercise (Ex: subjected to 10 weeks of low-intensity exercise), Sh+Ex, and BFR+Ex groups...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29177809/parallel-in-vivo-and-in-vitro-transcriptomics-analysis-reveals-calcium-and-zinc-signalling-in-the-brain-as-sensitive-targets-of-hbcd-neurotoxicity
#13
V Reffatto, J D Rasinger, T S Carroll, T Ganay, A-K Lundebye, I Sekler, M Hershfinkel, C Hogstrand
Hexabromocyclododecane (HBCD) is a brominated flame retardant (BFR) that accumulates in humans and affects the nervous system. To elucidate the mechanisms of HBCD neurotoxicity, we used transcriptomic profiling in brains of female mice exposed through their diet to HBCD (199 mg/kg body weight per day) for 28 days and compared with those of neuronal N2A and NSC-19 cell lines exposed to 1 or 2 µM HBCD. Similar pathways and functions were affected both in vivo and in vitro, including Ca2+ and Zn2+ signalling, glutamatergic neuron activity, apoptosis, and oxidative stress...
November 25, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/29142636/bone-flap-resorption-following-cranioplasty-with-autologous-bone-quantitative-measurement-of-bone-flap-resorption-and-predictive-factors
#14
Sang Pil Park, Jae Hoon Kim, Hee In Kang, Deok Ryeong Kim, Byung Gwan Moon, Joo Seung Kim
Objective: To quantitatively measure the degree of bone flap resorption (BFR) following autologous bone cranioplasty and to investigate factors associated with BFR. Methods: We retrospectively reviewed 29 patients who underwent decompressive craniectomy and subsequent autologous bone cranioplasty between April 2005 and October 2014. BFR was defined as: 1) decrement ratio ([the ratio of initial BF size/craniectomy size]-[the ratio of last BF/craniectomy size]) >0...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29126026/legacy-and-novel-brominated-flame-retardants-in-indoor-dust-from-beijing-china-occurrence-human-exposure-assessment-and-evidence-for-pbdes-replacement
#15
Jiandi Wang, Yuwei Wang, Zhixiong Shi, Xianqing Zhou, Zhiwei Sun
Levels of legacy brominated flame retardants (BFRs), including tetrabromobisphenol A (TBBPA), hexabromocyclododecane isomers (HBCDs) and polybrominated diphenyl ethers (PBDEs), and six currently used novel BFRs were determined in house dust and office dust collected from a community in Beijing, China. This is the first study where the three kinds of legacy BFRs and novel BFRs were all measured in dust samples from China. HPLC-MS/MS was used for the detection of TBBPA and HBCDs, and the other BFRs were tested on a GC-NCI/MS...
November 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29112627/impact-of-blood-flow-restriction-exercise-on-muscle-fatigue-development-and-recovery
#16
Florian Husmann, Thomas Mittlmeier, Sven Bruhn, Volker Zschorlich, Martin Behrens
PURPOSE: The present study was designed to provide mechanistic insight into the time-course and etiology of muscle fatigue development and recovery during and after low-intensity exercise when it is combined with blood flow restriction (BFR). METHODS: Seventeen resistance-trained males completed four sets of low-intensity isotonic resistance exercise under two experimental conditions: knee extension exercise combined with (i) BFR and (ii) without BFR (CON). Neuromuscular tests were performed before, during (immediately after each set of knee extension exercise) and 1, 2, 4, and 8 min after each experimental condition...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29106676/safety-and-efficacy-of-taurolidine-urokinase-versus-taurolidine-heparin-as-a-tunneled-catheter-lock-solution-in-hemodialysis-patients-a-prospective-randomized-controlled-study
#17
Fadwa Al-Ali, Ahmad F Hamdy, Abdullah Hamad, Mohamed Elsayed, Zafar Zafar Iqbal, Aisha Elsayed, Rania Ibrahim, Hoda Tolba, Hisham Buanan, Ashraf Fawzy
Background: Taurolidine citrate with heparin (Taurolock/Hep) is a promising central venous catheter lock solution. Despite its universal use among our hemodialysis patients, the prevalence of catheter malfunction was high. We aimed to compare Taurolock/Hep and taurolidine citrate with urokinase (Taurolock/U) as a catheter lock solution in order to identify whether either solution could reduce catheter-related dysfunction. Methods: In this prospective, randomized, controlled trial, patients were randomized to receive either Taurolock/Hep or Taurolock/U and were followed for 6 months...
July 4, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29091796/tbbpa-disposition-and-kinetics-in-pregnant-and-nursing-wistar-han-igs-rats
#18
Gabriel A Knudsen, Samantha M Hall, Alicia C Richards, Linda S Birnbaum
Tetrabromobisphenol-A (TBBPA) is a brominated flame retardant (BFR) commonly used in electronics to meet fire safety standards and has the largest worldwide production of any BFR. TBBPA has been detected in human breast milk and maternal/cord serum, indicating exposure to mothers, fetuses, and breastfeeding newborns although exposure to fetuses and newborns is poorly understood. Pregnant or nursing Wistar Han IGS rats were administered [(14)C]-TBBPA in a single dose (25 mg/kg, 2.5 μCi/kg) and euthanized between 0...
February 2018: Chemosphere
https://www.readbyqxmd.com/read/29084094/the-effects-of-practical-blood-flow-restriction-training-on-adolescent-lower-body-strength
#19
Paul E Luebbers, Emily V Witte, Johnathan Q Oshel
The purpose of this study was to examine the effects of a practical blood flow restriction (BFR) training program on lower-body strength of high school weightlifters. Twenty-five students were divided into three groups. For six weeks, each group completed the same resistance training program with the exception of the parallel back squat exercise (2 days/week), which was different for each group. One group (HI) completed a traditional high load (≥65% 1RM) back squat protocol with three sets of low repetitions (≤10)...
October 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29077147/melatonin-promotes-osteoblast-differentiation-of-bone-marrow-mesenchymal-stem-cells-in-aged-rats
#20
Z-M Chu, H-B Li, S-X Sun, Y-C Jiang, B Wang, Y-F Dong
OBJECTIVE: The current study was to explore the effect of melatonin on osteoporosis and relevant mechanisms. MATERIALS AND METHODS: We performed micro-CT to detect bone microstructure and ELISA to detect the contents of osteocalcin (OCN) and bone alkaline phosphatase (BAP) in serum. Double fluorescence labeling of calcein and tetracycline and toluidine blue staining were used to determine morphological indexes of bone tissues. Alizarin red staining and Oil Red O staining were performed to recognize bone cells and adipocytes...
October 2017: European Review for Medical and Pharmacological Sciences
keyword
keyword
117434
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"