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https://www.readbyqxmd.com/read/28747984/annual-tendency-of-research-papers-used-icr-mice-as-experimental-animals-in-biomedical-research-fields
#1
Ji Eun Kim, Jung Hoon Nam, Joon Young Cho, Kil Soo Kim, Dae Youn Hwang
Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades. However, annual tendency of research papers involving ICR mice in various biomedical fields has not been previously analyzed. In this study, we examined the numbers of papers that used ICR mice as experimental animals in the social science, natural science, engineering, medicine-pharmacy, marine agriculture-fishery, and art-kinesiology fields by analyzing big data...
June 2017: Laboratory Animal Research
https://www.readbyqxmd.com/read/28747355/the-math-biology-values-instrument-development-of-a-tool-to-measure-life-science-majors-task-values-of-using-math-in-the-context-of-biology
#2
Sarah E Andrews, Christopher Runyon, Melissa L Aikens
In response to calls to improve the quantitative training of undergraduate biology students, there have been increased efforts to better integrate math into biology curricula. One challenge of such efforts is negative student attitudes toward math, which are thought to be particularly prevalent among biology students. According to theory, students' personal values toward using math in a biological context will influence their achievement and behavioral outcomes, but a validated instrument is needed to determine this empirically...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/28747353/effectiveness-of-a-low-cost-graduate-student-led-intervention-on-study-habits-and-performance-in-introductory-biology
#3
Tyler D Hoskins, J D Gantz, Blake R Chaffee, Kel Arlinghaus, James Wiebler, Michael Hughes, Joyce J Fernandes
Institutions have developed diverse approaches that vary in effectiveness and cost to improve student performance in introductory science, technology, engineering, and mathematics courses. We developed a low-cost, graduate student-led, metacognition-based study skills course taught in conjunction with the introductory biology series at Miami University. Our approach aimed to improve performance for underachieving students by combining an existing framework for the process of learning (the study cycle) with concrete tools (outlines and concept maps) that have been shown to encourage deep understanding...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/28747160/adverse-events-in-women-and-children-who-have-received-intrapartum-antibiotic-prophylaxis-treatment-a-systematic-review
#4
Farah Seedat, Chris Stinton, Jacoby Patterson, Julia Geppert, Bee Tan, Esther R Robinson, Noel Denis McCarthy, Olalekan A Uthman, Karoline Freeman, Samantha Ann Johnson, Hannah Fraser, Colin Stewart Brown, Aileen Clarke, Sian Taylor-Phillips
BACKGROUND: Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. METHODS: We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016...
July 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28746842/the-droso4schools-project-long-term-scientist-teacher-collaborations-to-promote-science-communication-and-education-in-schools
#5
REVIEW
Sanjai Patel, Sophie DeMaine, Joshua Heafield, Lynne Bianchi, Andreas Prokop
Science communication is becoming an increasingly important part of a scientist's remit, and engaging with primary and secondary schools is one frequently chosen strategy. Here we argue that engaging with schools will be more effective when engaging with teachers through structured participation and/or collaboration, in order to respond to the realities of school life in designing the strategies used by science communicators. For example, the Manchester Fly Facility advocates the fruit fly Drosophila as an important research strategy for the discovery processes in the biomedical sciences...
July 23, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28746814/probabilistic-computations-for-attention-eye-movements-and-search
#6
Miguel P Eckstein
The term visual attention immediately evokes the idea of limited resources, serial processing, or a zoom metaphor. But evidence has slowly accumulated that computations that take into account probabilistic relationships among visual forms and the target contribute to optimizing decisions in biological and artificial organisms, even without considering these limited-capacity processes in covert attention or even foveation. The benefits from such computations can be formalized within the framework of an ideal Bayesian observer and can be related to the classic theory of sensory cue combination in vision science and context-driven approaches to object detection in computer vision...
July 26, 2017: Annual Review of Vision Science
https://www.readbyqxmd.com/read/28746768/de-extinction-and-the-community-of-being
#7
Curt Meine
Extinction deeply colors the way we think about conservation and the role of humans in nature. It is easy to overlook how recently, in fact, it has entered our consciousness. Only in the last two centuries has science sought to critically study life's origins, development, and diversification. Only in the last several generations have we identified and calibrated life's five major extinction events and speculated on their causes and effects. And only in recent decades have we come to appreciate the still-unfolding fate of life's diversity under the increasing influence of humanity...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28746767/the-moral-imagination-of-de-extinction
#8
Bruce Jennings
We live amidst the sixth great extinction of life on Earth, and we live under the sign of molecular biology and biotechnology. An ethical maxim that is well-nigh universally acknowledged holds that with great power comes great moral responsibility. For those who accept the science and embrace the responsibility, there are two rather different kinds of moral vision and moral imagination at work. Detractors of biotechnology say that we should see ourselves as creaturely good citizens of the biotic community, accepting and accommodating what evolutionary natural selection has bequeathed to us, warts and all...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28746766/conservation-genetics-precision-conservation-and-de-extinction
#9
Rob Desalle, George Amato
It has been estimated that three species on the planet now go extinct every hour and that this rate is orders of magnitude higher than the planet has seen in previous catastrophic extinction events. We clearly are in the midst of a sixth extinction, and this one is different from the previous five. Why? This sixth extinction is caused by the activity of a single species-us. If there is any hope of ameliorating this extinction, it will entirely be up to us, as the current stewards of this planet, to change the course...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28746010/beyond-nature-and-culture-fromm-s-existentialism
#10
Donald L Carveth
Though commonly seen as a member of the so-called "culturistic" school of psychoanalysis that rejected Freudian drive theory and embraced an "oversocialized" conception of human nature, Fromm's qualified essentialism and neo-Marxist existentialism significantly transcend both biological and social determinism (although he succumbs to the latter in regard to his theory of the Oedipus complex). His existential Freudo-Marxism contributes to the integration of psychoanalysis and social science. In place of the authoritarian superego and the pseudo-objective stance of the classical Freudians, Fromm offers conscientious, egalitarian, personalistic, and humane values...
August 2017: Psychoanalytic Review
https://www.readbyqxmd.com/read/28745336/human-embryonic-stem-cells-and-good-manufacturing-practice-report-of-a-1-day-workshop-held-at-stem-cell-biology-research-center-yazd-27-th-april-2017
#11
Fatemeh Akyash, Fatemeh Sadeghian-Nodoushan, Somayyeh Sadat Tahajjodi, Habib Nikukar, Ehsan Farashahi Yazd, Mostafa Azimzadeh, Harry D Moore, Behrouz Aflatoonian
This report explains briefly the minutes of a 1-day workshop entitled; "human embryonic stem cells (hESCs) and good manufacturing practice (GMP)" held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27(th) April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications...
May 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28745067/participants-understanding-of-informed-consent-for-biobanking-a-systematic-review
#12
Elizabeth R Eisenhauer, Alan R Tait, Soo Young Rieh, Cynthia M Arslanian-Engoren
Nurses are increasingly asked to obtain consent from participants for biobanking studies. Biobanking has added unique complexities to informed consent. The purpose of this systematic review was to evaluate participants' level of understanding of the information presented during the informed consent process unique to the donation of biological specimens for research. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were utilized to conduct the review. PubMed, EMBASE, CINAHL, PsycINFO, Scopus, Web of Science, and ProQuest bibliographic databases were searched...
July 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28741165/history-and-conceptual-developments-in-vascular-biology-and-angiogenesis-research-a-personal-view
#13
REVIEW
Andreas Bikfalvi
Vascular biology is an important scientific domain that has gradually penetrated many medical and scientific fields. Scientists are most often focused on present problems in their daily scientific work and lack awareness regarding the evolution of their domain throughout history and of how philosophical issues are related to their research field. In this article, I provide a personal view with an attempt to conceptualize vascular development research that articulates lessons taken from history, philosophy, biology and medicine...
July 24, 2017: Angiogenesis
https://www.readbyqxmd.com/read/28738015/observational-study-to-estimate-the-changes-in-the-effectiveness-of-bacillus-calmette-gu%C3%A3-rin-bcg-vaccination-with-time-since-vaccination-for-preventing-tuberculosis-in-the-uk
#14
Punam Mangtani, Patrick Nguipdop-Djomo, Ruth H Keogh, Lucy Trinder, Peter G Smith, Paul Em Fine, Jonathan Sterne, Ibrahim Abubakar, Emilia Vynnycky, John Watson, David Elliman, Marc Lipman, Laura C Rodrigues
BACKGROUND: Until recently, evidence that protection from the bacillus Calmette-Guérin (BCG) vaccination lasted beyond 10 years was limited. In the past few years, studies in Brazil and the USA (in Native Americans) have suggested that protection from BCG vaccination against tuberculosis (TB) in childhood can last for several decades. The UK's universal school-age BCG vaccination programme was stopped in 2005 and the programme of selective vaccination of high-risk (usually ethnic minority) infants was enhanced...
July 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28737822/liquid-crystal-templating-as-an-approach-to-spatially-and-temporally-organise-soft-matter
#16
REVIEW
Pim van der Asdonk, Paul H J Kouwer
Chemistry quickly moves from a molecular science to a systems science. This requires spatial and temporal control over the organisation of molecules and molecular assemblies. Whilst Nature almost by default (transiently) organises her components at multiple different length scales, scientists struggle to realise even relatively straightforward patterns. In the past decades, supramolecular chemistry has taught us the rules to precisely engineer molecular assembly at the nanometre scale. At higher length scales, however, we are bound to top-down nanotechnology techniques to realise order...
July 24, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28737374/an-integrated-sers-based-microdroplet-platform-for-the-automated-immunoassay-of-f1-antigens-in-yersinia-pestis
#17
Namhyun Choi, Jiyoung Lee, Juhui Ko, Jun Ho Jeon, Gi-Eun Rhie, Andrew J deMello, Jaebum Choo
The development of surface-enhanced Raman scattering (SERS)-based microfluidic platforms has attracted significant recent attention in the biological sciences. SERS is a highly sensitive detection modality, with microfluidic platforms providing many advantages over microscale methods, including high analytical throughput, facile automation and reduced sample requirements. Accordingly, the integration of SERS with microfluidic platforms offers significant utility in chemical and biological experimentation. Herein, we report a fully integrated SERS-based microdroplet platform for the automatic immunoassay of specific antigen fraction 1 (F1) in Yersinia pestis...
July 24, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28736756/advancing-the-science-of-myocardial-recovery-with-mechanical-circulatory-support-a-working-group-of-the-national-heart-lung-and-blood-institute
#18
Stavros G Drakos, Francis D Pagani, Martha S Lundberg, J Timothy Baldwin
The medical burden of heart failure (HF) has spurred interest in clinicians and scientists to develop therapies to restore the function of a failing heart. To advance this agenda, the National Heart Lung Blood Institute (NHLBI) convened a Working Group of experts on June 2-3, 2016 in Bethesda Maryland to develop recommendations for the NHLBI aimed at advancing the science of cardiac recovery in the setting of mechanical circulatory support (MCS). MSC devices effectively reduce volume and pressure overload that drives the cycle of progressive myocardial dysfunction, thereby triggering structural and functional reverse remodeling...
June 2017: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28736631/shifting-paradigm-of-developing-biologics-for-the-treatment-of-pancreatic-adenocarcinoma
#19
REVIEW
Ying Zeng, Agnieszka A Rucki, Xu Che, Lei Zheng
Pancreatic adenocarcinoma is still widely considered as a deadly disease even though there are substantial therapeutic developments in the past decade. Using combinational chemotherapy regimens, represented by gemcitabine plus nab-paclitaxel and FOLFIRINOX, was able to improve overall survival in patients with advanced disease to a limited extent. It has been a challenge to develop targeted therapies that are focused on the neoplasm cells of pancreatic adenocarcinoma. Recently, targeting the stroma and immune compartments of pancreatic adenocarcinoma has shown promising results...
June 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28735034/language-a-fresh-concept-to-integrate-syntactic-and-semantic-information-in-life-sciences
#20
Rémi Tournebize, Cédric Gaucherel
Several fields in biology tend to view the concept of information from one or the other of two extreme positions. Exclusionists base their stance of total rejection on gene-centrism and gene-determinism, typified by the recently-established endo-Darwinist school of life sciences. At the other end of the spectrum, there is total acceptance, as in the newly developed information-centred paradigms that populate biosemiotics. We propose in this paper to split the informational concepts into two irreducible (but linked) poles: the syntactic (concerned with the quantification of the information structure or complexity in a system), and the semantic (concerned with the organization rules and causality weights of interactions in a system)...
July 19, 2017: Bio Systems
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