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https://www.readbyqxmd.com/read/29332204/supplementing-living-kidney-transplantees-medical-records-with-donor-and-recipient-narratives
#1
Anne Hambro Alnæs
Norway provides total social welfare coverage for organ transplantations, including free immunosuppressive medication and prepaid life-long follow up for both recipients and donors. Despite these benefits the proportion of living kidney donors (LKD) has in recent years declined from around 40% (2011) of all kidney transplantations to 24% (2016). This study suggests harnessing patient- and donor-narratives as a tool for addressing the current fall in donation rates. The hospital records of 18 recipient/donor dyads were compared with patient and donor accounts elicited in semi-structured interviews...
January 13, 2018: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/29331842/predicting-1-year-disability-and-mortality-of-injured-older-adults
#2
Alvin D Jeffery, Mary S Dietrich, Cathy A Maxwell
PURPOSE: The growing incidence of elderly patients injured from falls, combined with a growing understanding of the contribution of cognition and frailty to mortality, prompted this work. Our objective was to develop a clinical risk prediction model for prognosticating disability and mortality among injured older adults 1 year after hospitalization. METHODS: Secondary analysis of prospective longitudinal data from an urban Level 1 trauma center. A proportional odds regression model was used to model mortality and functional status as ordinal outcomes...
January 6, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29331809/environmental-behavior-of-coated-nms-physicochemical-aspects-and-plant-interactions
#3
REVIEW
Martha L López-Moreno, Yarilyn Cedeño-Mattei, Sonia Janet Bailón-Ruiz, Edgar Vazquez-Nuñez, José A Hernandez-Viezcas, Oscar Juan Perales-Pérez, Guadalupe De la Rosa, José R Peralta-Videa, Jorge L Gardea-Torresdey
The application of nanomaterials (NMs) depends on several characteristics, including polydispersity, shape, surface charge, and composition, among others. However, the specific surface properties of bare NMs induce aggregation, reducing their utilization. Thus, different surface coverages have been developed to avoid or minimize NMs aggregation, making them more stable for the envisioned applications. Carbon-based NMs are usually coated with metals, while metal-based NMs are coated with natural organic compounds including chitosan, dextran, alginate, or citric acid...
December 25, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29331641/enzymes-from-piezophiles
#4
REVIEW
Toshiko Ichiye
The discovery of microbial communities in extreme conditions that would seem hostile to life leads to the question of how the molecules making up these microbes can maintain their structure and function. While microbes that live under extremes of temperature have been heavily studied, those that live under extremes of pressure, or "piezophiles", are now increasingly being studied because of advances in sample collection and high-pressure cells for biochemical and biophysical measurements. Here, adaptations of enzymes in piezophiles against the effects of pressure are discussed in light of recent experimental and computational studies...
January 10, 2018: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29331100/prevalence-associated-factors-and-control-level-of-asthma-symptoms-among-adolescents-in-northern-jordan
#5
Nihaya A Al-Sheyab, Mahmoud A Alomari
Objective To investigate the prevalence, associated factors, and control level of asthma in Jordanian high school students. Methods A descriptive, comparative, cross sectional design was used and a cluster sample of 2691 students (mean age = 14.5 years, 51.0% girls), drawn from eight randomly selected public high schools in Northern Jordan, participated in the study. Each student had the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire completed in the classroom between February and May, 2015...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#6
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29330220/regulation-of-drug-metabolism-by-the-interplay-of-inflammatory-signaling-steatosis-and-xeno-sensing-receptors-in-heparg-cells
#7
Norman Tanner, Lisa Kubik, Claudia Luckert, Maria Thomas, Ute Hofmann, Ulrich M Zanger, Linda Bohmert, Alfonso Lampen, Albert Braeuning
Non-alcoholic fatty liver disease (NAFLD), characterized by triglyceride deposition in hepatocytes due to imbalanced lipid homeostasis, is of increasing concern in Western countries, with progression to non-alcoholic steatohepatitis (NASH), liver fibrosis, and cirrhosis. Previous studies suggest a complex, mutual influence of hepatic fat accumulation, NASH-related inflammatory mediators, and drug-sensing receptors regulating xenobiotic metabolism. Here, we investigated the suitability of human HepaRG hepatocarcinoma cells as a model for NAFLD and NASH...
January 12, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29330163/affective-stimuli-in-behavioural-interventions-soliciting-for-health-check-up-services-and-the-service-users-socioeconomic-statuses-a-study-at-japanese-pachinko-parlours
#8
Naoki Kondo, Yoshiki Ishikawa
BACKGROUND: Socioeconomically vulnerable people are likely to have more health risks because of inadequate behaviour choices related to chronic social stresses. Brain science suggests that stress causes cognitively biased automatic decision making, preferring instant stress relief and pleasure (eg, smoking, alcohol use and drug abuse) as opposed to reflectively seeking health-maintenance services (eg, health check-ups). As such, hedonic stimuli that nudge people towards preventive actions could reduce health behaviour disparities...
January 12, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29330114/human-cd4-cd25-cd127hi-cells-and-the-th1-th2-phenotype
#9
Aditi Narsale, Rosita Moya, Joanna Davida Davies
CD4+ T cells that co-express CD25 and CD127 (CD25+CD127+) make up around 20% of all circulating CD4+ memory T cells in healthy people. The clinical significance of these cells is that in children with type 1 diabetes their relative frequency at diagnosis is significantly and directly correlated with rate of disease progression. The purpose of this study was to further characterize the CD25+CD127hi cells. We show that they are a mix of Th1 and Th2 cells however, they have a significantly higher relative frequency of pre-committed and committed Th2 cells, and secrete significantly higher levels of Th2-type cytokines than CD25- memory T cells...
January 9, 2018: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/29329972/enhanced-production-of-lactate-based-polyesters-in-escherichia-coli-from-a-mixture-of-glucose-and-xylose-by-mlc-mediated-catabolite-derepression
#10
Ryosuke Kadoya, Ken'ichiro Matsumoto, Kenji Takisawa, Toshihiko Ooi, Seiichi Taguchi
Lignocellulose-utilizing biorefinery is a promising strategy for the sustainable production of value-added products such as bio-based polymers. Simultaneous consumption of glucose and xylose in Escherichia coli was achieved by overexpression of the gene encoding Mlc, a multiple regulator of glucose and xylose uptake. This catabolite derepression gave the enhancement in the production of poly (15 mol% lactate-co-3-hydroxybutyrate), up to 65% from 50% (wild-type strain) in the cellular contents, of the Mlc-overexpressing strain of E...
January 9, 2018: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/29329535/measurement-of-the-potential-geographic-accessibility-from-call-to-definitive-care-for-patient-with-acute-stroke
#11
J Freyssenge, F Renard, A M Schott, L Derex, N Nighoghossian, K Tazarourte, C El Khoury
BACKGROUND: The World Health Organization refers to stroke, the second most frequent cause of death in the world, in terms of pandemic. Present treatments are only effective within precise time windows. Only 10% of thrombolysis patients are eligible. Late assessment of the patient resulting from admission and lack of knowledge of the symptoms is the main explanation of lack of eligibility. METHODS: The aim is the measurement of the time of access to treatment facilities for stroke victims, using ambulances (firemen ambulances or EMS ambulances) and private car...
January 12, 2018: International Journal of Health Geographics
https://www.readbyqxmd.com/read/29329527/emotional-and-cognitive-experiences-during-the-time-of-diagnosis-and-decision-making-following-a-prenatal-diagnosis-a-qualitative-study-of-males-presented-with-congenital-heart-defect-in-the-fetus-carried-by-their-pregnant-partner
#12
Tommy Carlsson, Elisabet Mattsson
BACKGROUND: Expectant fathers consider the second-trimester obstetric ultrasound examination as an important step towards parenthood, but are ill prepared for a detection of a fetal anomaly. Inductive research is scarce concerning their experiences and needs for support. Consequently, the aim of this study was to explore the emotional and cognitive experiences, during the time of diagnosis and decision-making, among males presented with congenital heart defect in the fetus carried by their pregnant partner...
January 12, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29329298/single-image-super-resolution-based-on-approximated-heaviside-functions-and-iterative-refinement
#13
Xin-Yu Wang, Ting-Zhu Huang, Liang-Jian Deng
One method of solving the single-image super-resolution problem is to use Heaviside functions. This has been done previously by making a binary classification of image components as "smooth" and "non-smooth", describing these with approximated Heaviside functions (AHFs), and iteration including l1 regularization. We now introduce a new method in which the binary classification of image components is extended to different degrees of smoothness and non-smoothness, these components being represented by various classes of AHFs...
2018: PloS One
https://www.readbyqxmd.com/read/29329243/characteristics-of-beidou-navigation-satellite-system-multipath-and-its-mitigation-method-based-on-kalman-filter-and-rauch-tung-striebel-smoother
#14
Qiuzhao Zhang, Wei Yang, Shubi Zhang, Xin Liu
Global Navigation Satellite System (GNSS) carrier phase measurement for short baseline meets the requirements of deformation monitoring of large structures. However, the carrier phase multipath effect is the main error source with double difference (DD) processing. There are lots of methods to deal with the multipath errors of Global Position System (GPS) carrier phase data. The BeiDou navigation satellite System (BDS) multipath mitigation is still a research hotspot because the unique constellation design of BDS makes it different to mitigate multipath effects compared to GPS...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29328340/interactions-between-brush-grafted-nanoparticles-within-chemically-identical-homopolymers-the-effect-of-brush-polydispersity
#15
So Jung Park, Seyong Kim, Daeseong Yong, Youngson Choe, Joona Bang, Jaeup U Kim
We systematically examined the polymer-mediated interparticle interactions between polymer-grafted nanoparticles (NPs) within chemically identical homopolymer matrices through experimental and computational efforts. In experiments, we prepared thermally stable gold NPs grafted with polystyrene (PS) or poly(methyl methacrylate) (PMMA), and they were mixed with corresponding homopolymers. The nanocomposites are well dispersed when the molecular weight ratio of free to grafted polymers, α, is small. For α above 10, NPs are partially aggregated or clumped within the polymer matrix...
January 12, 2018: Soft Matter
https://www.readbyqxmd.com/read/29328324/temperature-insensitive-optical-fiber-strain-sensor-with-ultra-low-detection-limit-based-on-capillary-taper-temperature-compensation-structure
#16
Changpeng Lang, Yi Liu, Kunjian Cao, Shiliang Qu
An optical fiber strain sensor based on capillary-taper compensation structure was proposed. The theoretical simulation by using the finite element analysis method shows a matching condition between the capillary length and the interference-cavity length to achieve the zero temperature crosstalk. Meanwhile, the strain sensitivity can also be improved greatly at the matching condition. We then set up an insertion controller system with high accuracy to make sure the interference-cavity length can match the capillary length...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29328006/parent-guardian-knowledge-regarding-implanted-shunt-type-setting-and-symptoms-of-malfunction-infection
#17
Laurie L Ackerman, Daniel H Fulkerson, Andrew Jea, Jodi L Smith
OBJECTIVE Patients with shunts often interact with providers distant from their primary hospital, making it important that the parent(s)/guardian(s) is well versed in the type of shunt implanted and symptoms of malfunction/infection. This is particularly important with magnetic-sensitive programmable valves, as the use of MRI becomes more prevalent. METHODS Over a 6-month period, primary caregivers of 148 consecutive patients who received shunts were prospectively administered questionnaires at clinic visits...
January 12, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29327577/interplay-of-interfacial-layers-and-blend-composition-to-reduce-thermal-degradation-of-polymer-solar-cells-at-high-temperature
#18
Sadok Ben Dkhil, Martin Pfannmöller, Rasmus R Schroeder, Riva Alkarsifi, Meriem Gaceur, Wolfgang Köntges, Hamed Heidari, Sara Bals, Olivier Margeat, Jörg Ackermann, Christine Videlot-Ackermann
The thermal stability of printed polymer solar cells at elevated temperatures needs to be improved to achieve high-throughput fabrication including annealing steps as well as long-term stability. During device processing, thermal annealing impact both the organic photoactive layer and the two interfacial layers making detailed studies of degradation mechanism delicate. A recently identified thermally stable PTB7:PC70BM blend as photoactive layer in combination with PEDOT:PSS as hole extraction layer is used here to focus on the impact of electron extraction layer (EEL) on the thermal stability of solar cells...
January 12, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29327248/introducing-new-technology-safely-into-urological-practice
#19
Siska Van Bruwaene, Benjamin Namdarian, Ben Challacombe, Ben Eddy, Ignace Billiet
PURPOSE: Surgical innovation is necessary to ensure continued improvement in patient care. However, several challenges unique to the surgical craft are encountered during the development and validation of such new technology. This article highlights some of these challenges and gives an overview of existing solutions. METHODS: A Pubmed review was performed about the "introduction of new technology" to identify challenges. Cross-referencing was used to explore the possible solutions per challenge...
January 11, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29326842/barriers-to-peritoneal-dialysis-in-aboriginal-patients
#20
Anna T Mathew, Joonho Park, Mala Sachdeva, Manish M Sood, Karen Yeates
Background: Aboriginal people in Canada have an unduly high burden of end-stage kidney disease (ESKD) and many live in rural settings. Peritoneal dialysis (PD) is a home-based dialysis modality that may provide a valuable alternative to in-center hemodialysis which is relatively underutilized by the Aboriginal population. Objective: We aim to assess the barriers to PD utilization in Aboriginal patients with ESKD. Design: This article is a prospective observational cohort study...
2018: Canadian Journal of Kidney Health and Disease
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