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https://www.readbyqxmd.com/read/29023993/pediatric-keloids-a-6-year-retrospective-review
#1
Afieharo I Michael, Samuel A Ademola, Olayinka A Olawoye, Ayodele O Iyun, Wasiu Adebayo, Odunayo M Oluwatosin
BACKGROUND/OBJECTIVES: Keloids are reportedly rare at the extremes of life. We sought to describe the epidemiology of pediatric keloids seen at the plastic surgery outpatient department of the University College Hospital, Ibadan. METHODS: We retrospectively reviewed all children younger than 19 years who presented with nonburn keloids between 2008 and 2014. Data were obtained on age; duration, size, and location of the keloid; family history; mode of treatment; and outcome...
October 11, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29023876/mri-assessment-of-treatment-delivery-for-interstitial-photodynamic-therapy-of-high-grade-glioma-in-a-preclinical-model
#2
Henri-Arthur Leroy, Maximilien Vermandel, Bertrand Leroux, Alain Duhamel, Jean-Paul Lejeune, Serge Mordon, Nicolas Reyns
BACKGROUND: High-grade gliomas are primary brain tumors that have shown increasing incidence and unfavorable outcomes. Local control is crucial to the management of this pathology. Photodynamic therapy (PDT), based on the light-induced activation of a photosensitizer (PS), achieves local treatment by inducing selective lesions in tumor tissue. OBJECTIVES: Previous studies have reported the outcomes of PDT for glioblastoma via immunohistological data. Our study aimed to evaluate MRI findings, including diffusion, and perfusion sequences, compared with immunohistological data from the same population to address the efficiency of light fractionation...
October 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29022789/the-impact-of-mechanism-on-the-management-and-outcome-of-penetrating-colonic-trauma
#3
G V Oosthuizen, V Y Kong, T Estherhuizen, J L Bruce, G L Laing, J J Odendaal, D L Clarke
Introduction In light of continuing controversy surrounding the management of penetrating colonic injuries, we set out to compare the outcome of penetrating colonic trauma according to whether the mechanism of injury was a stab wound or a gunshot wound. Methods Our trauma registry was interrogated for the 5-year period from January 2012 to December 2016. All patients over the age of 18 years with penetrating trauma (stab or gunshot) and with intraoperatively proven colonic injury were reviewed. Details of the colonic and concurrent abdominal injuries were recorded, together with the operative management strategy...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29022143/comorbidity-of-gastrointestinal-disorders-migraine-and-tension-type-headache-a-cross-sectional-study-in-iran
#4
Fahimeh Martami, Zeinab Ghorbani, Maryam Abolhasani, Mansoureh Togha, Alipasha Meysamie, Alireza Sharifi, Soodeh Razeghi Jahromi
Migraine can be accompanied by some gastrointestinal (GI) disorders. In this study, we aimed to investigate the relationship between migraine and tension-type headache (TTH) and different lower and upper GI disorders as well as non-alcoholic fatty liver (NAFLD) and cholelithiasis. This cross-sectional study included 1574 overweight and obese participants who were referred to the Obesity Research Center of Sina Hospital, Tehran, Iran. The diagnosis of migraine and TTH was made by an expert neurologist based on the international classification of headache disorders-III β (ICHD III β)...
October 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29020937/the-prognostic-value-of-pretreatment-tumor-apparent-diffusion-coefficient-values-in-nasopharyngeal-carcinoma
#5
Dan-Fang Yan, Wen-Bao Zhang, Shan-Bao Ke, Feng Zhao, Sen-Xiang Yan, Qi-Dong Wang, Li-Song Teng
BACKGROUND: Diffusion-weighted MR imaging (DWI) has increasingly contributed to the management of nasopharyngeal carcinoma (NPC) patients. The objective of this paper was to explore the prognostic significance of apparent diffusion coefficient (ADC) values in 93 NPC patients. METHODS: This retrospective study included 93 newly diagnosed NPC patients. Pretreatment ADC values were determined and compared with patients' age, gender, alcohol intake, smoking, tumor volume, pathological type, tumor stage, and nodal stage...
October 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29016917/cannabis-for-the-treatment-of-chronic-pain-in-the-era-of-an-opioid-epidemic-a-symposium-based-review-of-sociomedical-science
#6
Dermot P Maher, Daniel B Carr, Kevin Hill, Brian McGeeney, Valerie Weed, William C Jackson, David J DiBenedetto, Edward M Moriarty, Ronald J Kulich
Objective: This manuscript reviews medical literature published pertaining to the management of chronic pain with medical marijuana therapy (MMJ), with an emphasis on the social, medical, and legal aspects of therapy. Design: Narrative review of peer-reviewed literature. Methods: The 3rd Symposium on Controlled Substances and Their Alternatives for the Treatment of Pain was held in Boston on February 27, 2016, with a focus on MMJ for the treatment of chronic pain...
July 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28991144/colon-sparing-surgery-for-clostridium-difficile
#7
David N Naumann, Aneel Bhangu, Douglas M Bowley
There has been recent evidence from a large multi-center study sponsored by the Eastern Association for the Surgery of Trauma that colon-sparing surgery reduces mortality for patients with severe Clostridium difficile associated disease (CDAD) when compared to total colectomy. Amoebic colitis shares many pathologic and clinical features to CDAD, such as worsening diarrhoea, patchy colonic ulceration and necrosis, toxic megacolon, pseudomembranous colitis, perforation, and death. However, published research regarding amoebic colitis is sparse...
October 4, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28990309/making-sense-of-frailty-an-ethnographic-study-of-the-experience-of-older-people-living-with-complex-health-problems
#8
Julie Kathryn Skilbeck, Antony Arthur, Jane Seymour
AIM: To explore how older people with complex health problems experience frailty in their daily lives. BACKGROUND: A better understanding of the personal experience of frailty in the context of fluctuating ill-health has the potential to contribute to the development of personalised approaches to care planning and delivery. DESIGN: An ethnographic study of older people, living at home, receiving support from a community matron service in a large city in the North of England...
October 9, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/28989174/new-treatment-paradigms-for-adpkd-moving-towards-precision-medicine
#9
REVIEW
Matthew B Lanktree, Arlene B Chapman
The natural history of autosomal dominant polycystic kidney disease (ADPKD) is characterized by a variable rate of cyst development and increase in total kidney volume (TKV), variable kidney function decline and age of onset of end-stage renal disease (ESRD), and variable presentation of renal and extrarenal manifestations. Precision medicine is proposed to improve patient outcomes by tailoring therapy to the specific genetic background, pathophysiology, disease burden, prognosis and status of each individual...
October 9, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28988618/hospital-burden-of-long-term-genitourinary-and-gastrointestinal-toxicity-after-radical-radiotherapy-for-prostate-cancer
#10
Elaine J Redmond, Katelyn S Dolbec, Aisling S Fawaz, Hugh D Flood, Subhasis K Giri
INTRODUCTION: Treatment options for prostate cancer (PCa) include radical radiotherapy (RT) and radical prostatectomy, both of which have comparable oncological outcomes. The aim of this study was to investigate the hospital burden of long-term genitourinary and gastrointestinal toxicity among patients with PCa who were treated with radiotherapy at our institution. METHODS: The radiotherapy department database was used retrospectively to identify all patients who underwent radiotherapy for PCa from January 2006 to January 2008...
October 4, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28987824/economic-analysis-of-a-nurse-led-programme-for-comorbidities-management-of-rheumatoid-arthritis-patients
#11
Charline Mourgues, Marie Blanquet, Laurent Gerbaud, Martin Soubrier, Maxime Dougados
OBJECTIVES: Rheumatoid arthritis (RA) cause major functional, psychological, social and occupational repercussions for patients and has important economic consequences for society. The principal objective of this work was to determine the economic pertinence of a staff nurse specialised in preventive management for these patients. METHODS: The COMEDRA multicentre randomised controlled clinical trial, conducted from March 2011 to June 2012, showed the effectiveness of a nurse-led programme dedicated to the management of comorbidities trough the promotion of 11 preventive procedures...
October 4, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28986037/a-practical-approach-to-the-management-of-micronutrients-and-other-nutrients-of-concern-in-food-exchange-lists-for-meal-planning
#12
Giuseppe Russolillo-Femenías, Susana Menal-Puey, J Alfredo Martínez, Iva Marques-Lopes
No abstract text is available yet for this article.
October 4, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28984650/diagnosis-and-clinical-management-of-long-qt-syndrome
#13
Christian Steinberg
PURPOSE OF REVIEW: To give an overview over the substantial advances in the diagnosis and management of Long-QT syndrome since its first description 60 years ago. RECENT FINDINGS: LQT syndrome remains the most common inherited arrhythmia and is a leading cause for sudden unexplained death accounting for up to 20-25% of cases. Rapid progress of genetic technology over the past 2 decades has significantly improved our understanding of molecular and genetic mechanisms of LQT...
October 4, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28984430/modeling-sediment-transport-in-qatar-application-for-coastal-development-planning
#14
Ruqaiya Yousif, Chris Warren, Radhouan Ben-Hamadou, Sinan Hurevoglu
Hydrodynamics and sediment transport are key physical processes contributing to habitat structure within the marine environment. Coastal development that results in the alteration of these processes (e.g., changing water flushing and/or sedimentation rates) can have detrimental impacts on sensitive systems. This is a current relevant issue in Qatar as its coastal regions continue to be developed, not only around the capital of Doha, but in many areas around this Arabian Gulf peninsula. The Northeastern Qatari coast is comprised of diverse and sensitive flora and fauna such as seagrass and macro-algae meadows, coral reefs/patches, turtles and dugongs that tolerate harsh environmental conditions...
October 6, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28984060/a-practical-approach-to-the-management-of-nocturia
#15
Matthias Oelke, Stefan De Wachter, Marcus J Drake, Antonella Giannantoni, Mike Kirby, Susan Orme, Jonathan Rees, Philip van Kerrebroeck, Karel Everaert
AIM: To raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways. METHODS: A multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences. RESULTS: Nocturia is defined as the need to void ≥1 time during the sleeping period of the night. Clinically relevant nocturia (≥2 voids per night) affects 2%-18% of those aged 20-40 years, rising to 28%-62% for those aged 70-80 years...
October 5, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28980290/atherosclerosis-in-antineutrophil-cytoplasmic-autoantibody-anca-associated-vasculitis
#16
Katarzyna Życińska, Anna Borowiec
The primary systemic vasculitides are heterogeneous, multisystem disorders characterized by inflammation and necrosis of small and medium blood vessels. Patients with antineutrophil cytoplasmic autoantibodies associated vasculitis have increased mortality rate as a consequence of cardiovascular disease. Measures to reduce the risk of cardiovascular disease should be integral to the management of systemic vasculitis. The preventive therapy for accelerated atherosclerosis in systemic vasculitis should be based on aggressive approach against inflammation and against risk factors of premature atherosclerosis such as hypertension, smoking, inactivity, obesity and unhealthy diet...
October 5, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28973704/neoadjuvant-and-adjuvant-therapies-for-breast-cancer
#17
REVIEW
Susmitha Apuri
Breast cancer remains the most common cancer in women in the United States, the second most common cause of cancer death, and the main cause of death in women ages 45 to 55 years. Molecular analyses have shown that breast cancer is divided into several subtypes (luminal A, luminal B, human epidermal growth factor receptor 2 [HER2] enriched, and basal-like), based on microarray techniques. Patients diagnosed as having breast cancer may undergo adjuvant or neoadjuvant chemotherapy, depending on the tumor size, hormone receptor, HER2/neu status, and desire for breast preservation...
October 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28971780/herpes-labialis-an-update
#18
Alexander K C Leung, Benjamin Barankin
BACKGROUND: Herpes labialis is characterized by recurrent vesicular eruptions primarily on the lips and perioral skin. The condition is contagious, can cause significant discomfort/pain, and can have an adverse effect on quality of life. OBJECTIVE: To update the evaluation and treatment of herpes labialis. METHODS: A PubMed search was completed in Clinical Queries using the key term "herpes labialis". Patents were searched using the key term "herpes labialis" from www...
October 3, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28967357/in-the-spine-or-in-the-brain-recent-advances-in-pain-neuroscience-applied-in-the-intervention-for-low-back-pain
#19
REVIEW
Jo Nijs, Jacqui Clark, Anneleen Malfliet, Kelly Ickmans, Lennard Voogt, Sanneke Don, Hester den Bandt, Dorien Goubert, Jeroen Kregel, Iris Coppieters, Wim Dankaerts
Conservative, surgical and pharmacological strategies for chronic low back pain (CLBP) management offer at best modest effect sizes in reducing pain and related disability, indicating a need for improvement. Such improvement may be derived from applying contemporary pain neuroscience to the management of CLBP. Current interventions for people with CLBP are often based entirely on a "biomedical" or "psychological" model without consideration of information concerning underlying pain mechanisms and contemporary pain neuroscience...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28965265/preferences-of-patients-and-pharmacists-with-regard-to-the-management-of-drug-drug-interactions-a-choice-based-conjoint-analysis
#20
Mette Heringa, Annemieke Floor-Schreudering, Hans Wouters, Peter A G M De Smet, Marcel L Bouvy
INTRODUCTION: The management of drug-drug interactions (DDIs) is a complex process in which risk-benefit assessments should be combined with the patient's perspective. OBJECTIVE: The aim of this study was to determine patients' and pharmacists' preferences regarding DDI management. METHODS: We conducted a choice-based conjoint survey about a fictitious DDI concerning the combination of a cardiovascular drug and an antibiotic for pneumonia...
September 30, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
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