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https://www.readbyqxmd.com/read/29665572/diagnostic-and-treatment-practices-for-psychogenic-nonepileptic-and-epileptic-seizures-in-namibia
#1
Anina du Toit, Chrisma Pretorius
PURPOSE: Information about existing healthcare resources for the management of seizures in developing countries is lacking. These countries are often poorly equipped to deal with the immense burden of costs, mortality, stigma, seizure-related disability, and comorbidities presented by seizure disorders. This study aimed to contribute to the goals of the International League Against Epilepsy (ILAE) by investigating the resources available for patients with seizure in Namibia. METHODS: Two separate surveys on the diagnostic and treatment practices for epileptic seizures (ES) and psychogenic nonepileptic seizures (PNES) were administered to private healthcare practitioners (HCPs) in Namibia...
April 13, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29665461/targeting-acceptance-in-the-management-of-food-craving-the-mediating-roles-of-eating-styles-and-thought-suppression
#2
Jaime A Coffino, Sydney Heiss, Julia M Hormes
Food craving is now widely considered to be a cognitively motivated state. Acceptance-based treatments are effective in reducing the adverse impact of food cravings on consumption, via a hypothesized decrease in experiential avoidance. The mechanisms that drive the success of acceptance-based management of craving remain to be empirically tested. This study examined the role of eating styles and thought suppression as mediators in the relationship between experiential avoidance and craving. Participants (n = 298, 51...
April 12, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29663173/current-status-of-neoadjuvant-endocrine-therapy-in-early-stage-breast-cancer
#3
REVIEW
Tomás Reinert, Rodrigo Gonçalves, Matthew J Ellis
Neoadjuvant endocrine therapy (NET) with Ki67-based response monitoring is a practical, cost-effective approach to the management of clinical stage II and III estrogen receptor-positive (ER+) breast cancer. In addition to marked improvements in rates of breast conservation, the identification of extreme responders on the basis of the preoperative endocrine prognostic index (PEPI) provides a rationale to avoid chemotherapy on the basis of highly favorable prognosis in some patients. Finally, samples accrued from patients treated with neoadjuvant therapy are providing valuable insights into the molecular basis for intrinsic resistance to endocrine therapy and promise a more rational basis and precise approach to the systemic treatment of ER+ breast cancer...
April 16, 2018: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29662550/radiotherapy-and-checkpoint-inhibitors-a-winning-new-combination
#4
REVIEW
Eric C Ko, Silvia C Formenti
Immune checkpoint blockade has recently emerged as an important therapeutic approach to the management of malignancies across multiple disease settings. Concomitantly, there has been an increasing appreciation for the role of radiotherapy in eliciting and promoting tumor-directed immune responses. In this review, we discuss the clinical evidence to date on combinations of radiotherapy with immune checkpoint inhibitors, both from the standpoint of safety and efficacy. We highlight important but yet-unanswered questions for this combination approach, as well as their implications for future prospective studies...
2018: Therapeutic Advances in Medical Oncology
https://www.readbyqxmd.com/read/29661987/review-of-the-latest-percutaneous-devices-in-critical-limb-ischemia
#5
REVIEW
Leila Haghighat, Sophia Elissa Altin, Robert R Attaran, Carlos Mena-Hurtado, Christopher J Regan
Critical limb ischemia (CLI) is a terminal stage of peripheral arterial disease that, in the absence of intervention, may lead to lower extremity amputation or death. Endovascular interventions have become a first-line approach to the management of CLI and have advanced considerably within the past decade. This review summarizes the types of percutaneous devices and the techniques that are available for the management of CLI and the data supporting their use. These include devices that establish and maintain vessel patency, including percutaneous transluminal angioplasty, drug-coated balloons, bare metal stents, drug-eluting stents, bioresorbable vascular scaffolds, and atherectomy; devices that provide protection from embolization; and, cell-based therapies...
April 14, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29651313/risk-factors-for-osteoporosis-in-postmenopausal-women-from-the-point-of-view-of-primary-care-gynecologist
#6
Damir Franic, Ivan Verdenik
Introduction: Osteoporosis is a highly prevalent public health problem with osteoporosis-related fractures that account for high morbidity and mortality. Therefore, prevention strategies and early detection of osteoporosis should be carried out in primary gynaecological care units, so as to substantially reduce the risk of fractures and allow the best treatment option for a particular woman. Methods: From 2002 to 2011, we recruited 2956 women. Of the total number of women, we additionally extrapolated 1274 women aged 60-75 years, assumingly, the group of women at higher risk of osteoporosis...
March 2018: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/29644264/laparoscopic-approach-to-the-management-of-penetrating-traumatic-diaphragmatic-injury
#7
Teo Li Tserng, Maria Benita Gatmaitan
Background: Traditionally, laparotomy/thoracotomy is the standard approach for thoracoabdominal injuries. However, it has a non-therapeutic rate of 12-40% and 40% morbidity. Laparoscopy, as a diagnostic and therapeutic modality, has evolved to be integral to general and subspecialty surgeons in the management of patients. However, its use in the field of trauma surgery has been limited. We present a case of traumatic diaphragmatic injury from a low velocity penetrating wound successfully repaired through laparoscopic approach...
August 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29629314/surgical-resection-of-pancreatic-neuroendocrine-neoplasm-by-minimally-invasive-surgery-the-robotic-approach
#8
REVIEW
Roxanne Y A Teo, Brian K P Goh
Over the past decade, there has been increasing adoption of minimally invasive pancreatic surgery world-wide and this has naturally expanded to the management of pancreatic neuroendocrine neoplasms (PNENs). More recently, robotic pancreatic surgery (RPS) was introduced to overcome the limitations during laparoscopic pancreatic surgery (LPS). Due to the relative rarity of PNEN and the novelty of minimally invasive pancreatic surgery in particular RPS today, the evidence for robotic surgery in PNENs remains extremely limited...
February 2018: Gland Surgery
https://www.readbyqxmd.com/read/29627424/asthma-across-the-lifespan-time-for-a-paradigm-shift
#9
Stanley J Szefler
We have a unique opportunity to significantly reduce the worldwide burden of asthma in children and impact respiratory outcomes in adults. However, this will require a paradigm shift that is directed at altering the natural history of asthma, reducing asthma exacerbations and preventing long-term adverse outcomes of childhood asthma. Attention should continue to be directed toward minimizing risk as well as impairment with a goal to achieve optimal control. Based on several NIH studies conducted over the last 10 years we now have the tools necessary to accomplish this goal...
April 5, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29621966/the-epidemiology-of-urinary-tract-infections-in-hiv-positive-patients-at-a-tertiary-care-university-hospital-in-central-europe-2011-2016
#10
Romana Klasinc, Armin Rieger, Elisabeth Presterl, Thomas Wrba, Magda Diab-Elschahawi
OBJECTIVES: There is limited published data concerning recent epidemiology of urinary tract infections (UTI) in HIV-patients, thus we analysed independent risk factors for UTI in HIV positive individuals and antimicrobial resistance rates of E. coli to antimicrobial agents commonly used in UTI. To determine the prevalence of symptomatic urinary tract infections (UTI) in HIV-patients we performed a retrospective case-control study. METHODS: We included 313 HIV-patients, 101 with UTI and 212 age and gender matched controls, attending the HIV outpatient clinic at the Vienna University hospital (VUH) over a period from January 2011 to September 2016...
April 5, 2018: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/29619276/use-of-anticoagulants-remains-a-significant-threat-to-timely-hip-fracture-surgery
#11
Razvan Taranu, Chelsea Redclift, Patrick Williams, Marina Diament, Anne Tate, Jamie Maddox, Faye Wilson, Will Eardley
Introduction: Hip fracture remains the biggest single source of morbidity and mortality in the elderly trauma population, and any intervention focused on quality improvement and system efficiency is beneficial for both patients and clinicians. Two of the variables contributory to improving care and efficiency are time to theater and length of stay, with the overall goal being to improve care as reflected within the achievement of best practice tariff. One of the biggest barriers to optimizing these variables is preinjury anticoagulation...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29619209/contemporary-approaches-to-the-management-of-polycystic-ovary-syndrome
#12
REVIEW
Renato Pasquali
Polycystic ovary syndrome (PCOS) is a common disorder in women in their reproductive years and is characterized by androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. It is also associated with several metabolic abnormalities, particularly insulin resistance and obesity, which play an important role in the pathophysiology of PCOS and, in particular, negatively influence ovarian function and fertility. This review article summarizes the available treatment for women with PCOS. Specifically, current and potentially new therapies are discussed...
April 2018: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29618933/current-perspectives-on-tree-nut-allergy-a-review
#13
REVIEW
Tamar Weinberger, Scott Sicherer
Tree nut (TN) allergy is common and often severe. It has become an important health concern as availability and consumption have increased. Prevalence varies by age and geographic region and appears to have increased in children. Accidental ingestion of TNs is common. Unfortunately, there is a lower likelihood of resolution of TN allergy, roughly 10%. TN-specific skin tests and serum immunoglobulin E levels can help aid in the diagnosis of TN allergy, but a careful medical history is important because a positive test in isolation is not typically diagnostic...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/29610773/are-they-high-on-steroids-tailored-interventions-help-improve-screening-for-steroid-induced-hyperglycaemia-in-hospitalised-patients
#14
Punith Kempegowda, Alana C Livesey, Laura McFarlane-Majeed, Joht Singh Chandan, Theresa Smyth, Martha Stewart, Karen Blackwood, Michelle McMahon, Anitha Vijayan Melapatte, Sofia Salahuddin, Jonathan Webber, Sandip Ghosh
Steroid-induced hyperglycaemia (SIH) is a common adverse effect in patients both with and without diabetes. This project aimed to improve the screening and diagnosis of SIH by improving the knowledge of healthcare professionals who contribute to the management of SIH in hospitalised patients. Monitoring and diagnosis of SIH were measured in areas of high steroid use in our hospital from May 2016 to January 2017. Several interventions were implemented to improve knowledge and screening for SIH including a staff education programme for nurses, healthcare assistants and doctors...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29606889/management-and-prognosis-of-patients-with-liver-metastases-from-gestational-trophoblastic-neoplasia-a-retrospective-cohort-study
#15
Liju Zong, Junjun Yang, Xiaoyu Wang, Yujia Kong, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang
Purpose: The aims of this study were to analyze the clinical features, identify prognostic factors, and evaluate the survival outcomes of gestational trophoblastic neoplasia (GTN) patients with liver metastases. Patients and methods: Forty patients with liver metastases arising from GTNs, who were treated at the Peking Union Medical College Hospital (Beijing, People's Republic of China) between January 1999 and December 2015, were recruited from the institutional database, and their medical records were reviewed...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29603904/the-chromosome-18-clinical-resource-center
#16
Jannine D Cody, Minire Hasi-Zogaj, Patricia Heard, Annice Hill, David Rupert, Courtney Sebold, Bridgette Soileau, Daniel E Hale
BACKGROUND: The Chromosome 18 Clinical Research Center has created a pediatrician-friendly virtual resource center for managing patients with chromosome 18 abnormalities. To date, children with rare chromosome abnormalities have been cared for either symptomatically or palliatively as a reaction to the presenting medical problems. As we enter an era of genomic-informed medicine, we can provide children, even those with individually unique chromosome abnormalities, with proactive medical care and management based on the most contemporary data on their specific genomic change...
March 30, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29602259/an-algorithmic-approach-for-the-management-of-ostial-right-coronary-artery-chronic-total-occlusions
#17
Alexandre Avran, Marouane Boukhris, Laurent Drogoul, Emanouil S Brilakis
Treatment of ostial chronic total occlusions (CTOs) of the right coronary artery (RCA) can be challenging. We present an algorithmic approach to the management of such lesions that incorporates all contemporary equipment and techniques. If the RCA ostium can be engaged with a guide catheter then antegrade crossing attempts should be performed. If the antegrade guidewire enters the subintimal space, re-entry into the distal true lumen is performed provided that the antegrade guide catheter provides enough support...
March 30, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29601466/longitudinal-clival-fracture-in-a-child-case-report-and-review-of-the-literature
#18
Bedia Gulen, Mustafa Serinken, Ozgur Karcioglu, Okkes Taha Kucukdagli
Clival fracture is a rare and serious injury, which mostly results in the death of the victim before reaching the hospital. The entity is hardly diagnosed in the early phase because of high mortality rates and deficiencies in completion of radiological imaging. The incidence of diagnoses increased year by year after the usage of computed tomography gained widespread availability. In this article, we aimed to present radiological and clinical characteristics of a 5-year-old patient brought to the emergency department after a motor vehicle accident...
April 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29595231/habit-reversal-therapy-quickly-and-significantly-contributes-to-the-management-of-children-with-atopic-eczema
#19
A Bewley
No abstract text is available yet for this article.
March 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29595118/evaluation-of-the-antidiabetic-property-of-capparis-ovata-desf-var-palaestina-zoh-extracts-using-in-vivo-and-in-vitro-approaches
#20
Mehmet Evren Okur, Derya Cicek Polat, Hanefi Ozbek, Sezen Yilmaz, Aysegul Yoltas, Rana Arslan
This paper focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. </p><p> Methods: Alloxan-induced diabetic BALB-c mice were administered intraperitoneally with 100, 300, 500mg/kg doses of ethanol and aqueous extracts of buds and fruits. Furthermore, HPLC, phenolic and flavonoid compounds analysis, ABTS and DPPH free radical scavenging activity, anti-inflammatory activity, agar well diffusion and MIC tests were carried out...
March 27, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
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