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https://www.readbyqxmd.com/read/28633544/medical-versus-surgical-management-of-penetrating-crohn-s-disease-the-current-situation-and-future-perspectives
#1
Seema A Patil, Raymond K Cross
The development of penetrating Crohn's disease (CD) occurs in up to 50% of patients over the course of their lifetime. While the presentation of these complications, including free perforation, intra-abdominal abscess, and enteric fistula, are usually obvious, the management can require a nuanced approach, with distinct short and long-term approaches. Areas covered: This review discusses medical and surgical methods of treating these complications, including the role of percutaneous drainage of abscesses, the implications of a stricture associated with a fistula, and the efficacy of postoperative anti-TNF therapy in preventing recurrence after surgical treatment...
June 21, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28631241/improving-self-management-of-type-2-diabetes-in-overweight-and-inactive-patients-through-an-educational-and-motivational-intervention-addressing-diet-and-physical-activity-a-prospective-study-in-naples-south-italy
#2
Francesca Gallé, Valeria Di Onofrio, Assunta Cirella, Mirella Di Dio, Alessandra Miele, Tiziana Spinosa, Giorgio Liguori
INTRODUCTION: Nutrition and physical activity are key elements in the prevention and management of type 2 diabetes. A community-based, multidisciplinary educational intervention aimed to improve quality of life and disease self-management in sedentary, overweight/obese type 2 diabetic patients was implemented in Naples, South Italy. METHODS: The 9-month intervention included a motivational program, a nutrition program, and an exercise program. Satisfaction, worry, and embarrassment regarding their condition, together with disease-related behaviors and propensity towards physical activity, were evaluated through a validated questionnaire before and after the intervention; health status perception was evaluated through the short-form 12 questionnaire...
June 19, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28630687/emerging-antimicrobial-resistance-in-early-and-late-onset-neonatal-sepsis
#3
Lamiaa Mohsen, Nermin Ramy, Dalia Saied, Dina Akmal, Niveen Salama, Mona M Abdel Haleim, Hany Aly
BACKGROUND: Compared to developed countries, the use of antimicrobials in Egypt is less regulated and is available over the counter without the need for prescriptions. The impact of such policy on antimicrobial resistance has not been studied. This study aimed to determine the prevalence of early and late onset sepsis, and the frequency of antimicrobial resistance in a major referral neonatal intensive care unit (NICU). METHODS: The study included all neonates admitted to the NICU over a 12-month period...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28630589/laparoscopic-colorectal-surgery-for-colorectal-polyps-experience-of-ten-years
#4
Audrius Dulskas, Žygimantas Kuliešius, Narimantas E Samalavičius
Background. Laparoscopy or its combination with endoscopy is the next step for "difficult" polyps. The purpose of the paper was to review the outcomes of the laparoscopic approach to the management of "difficult" colorectal polyps. Materials and methods. From 2006 to 2016, 58 patients who underwent laparoscopic treatment for "difficult" polyps that could not be treated by endoscopy at the National Cancer Institute, Lithuania, were included. The demographic data, the type of surgery, length of post-operative stay, complications, and final pathology were reviewed prospectively...
2017: Acta medica Lituanica
https://www.readbyqxmd.com/read/28623004/variable-methodological-quality-and-use-found-in-systematic-reviews-referenced-in-stemi-clinical-practice-guidelines
#5
Jared Scott, Benjamin Howard, Philip Sinnett, Michael Schiesel, Jana Baker, Patrick Henderson, Matt Vassar
BACKGROUND: The objective of this study was to assess the methodological quality and clarity of reporting of the systematic reviews (SRs) supporting clinical practice guideline (CPG) recommendations in the management of ST-elevation myocardial infarction (STEMI) across international CPGs. METHODS: We searched 13 guideline clearinghouses including the National Guideline Clearinghouse and Guidelines International Network (GIN). To meet inclusion criteria CPGs must be pertinent to the management of STEMI, endorsed by a governing body or national organization, and written in English...
June 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28621799/clinical-guideline-for-the-management-of-odontogenic-infections-in-the-tertiary-setting
#6
Sushma Vytla, Dieter Gebauer
BACKGROUND: Odontogenic infections are a common presentation to Emergency Departments of Australian hospitals. Due to the limited training in diagnosis and treatment of dental conditions, these patients can present a challenge for the medical practitioner. The objective of this study was to provide an evidence-based approach to the management of odontogenic infections in adults presenting to Royal Perth Hospital. METHODS: A literature search was conducted to identify evidence based guidelines for the management of odontogenic infections in the tertiary hospital setting...
June 16, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28619065/open-issues-in-mucopolysaccharidosis-type-i-hurler
#7
REVIEW
Rossella Parini, Federica Deodato, Maja Di Rocco, Edoardo Lanino, Franco Locatelli, Chiara Messina, Attilio Rovelli, Maurizio Scarpa
Mucopolysaccharidosis I-Hurler (MPS I-H) is the most severe form of a metabolic genetic disease caused by mutations of IDUA gene encoding the lysosomal α-L-iduronidase enzyme. MPS I-H is a rare, life-threatening disease, evolving in multisystem morbidity including progressive neurological disease, upper airway obstruction, skeletal deformity and cardiomyopathy. Allogeneic hematopoietic stem cell transplantation (HSCT) is currently the gold standard for the treatment of MPS I-H in patients diagnosed and treated before 2-2...
June 15, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28615732/managing-rheumatic-and-musculoskeletal-diseases-past-present-and-future
#8
REVIEW
Gerd R Burmester, Johannes W J Bijlsma, Maurizio Cutolo, Iain B McInnes
Progress in rheumatology has been remarkable in the past 70 years, favourably affecting quality of life for people with rheumatic and musculoskeletal diseases. Therapeutics have advanced considerably in this period, from early developments such as the introduction of glucocorticoid therapy to the general use of methotrexate and other disease-modifying agents, followed by the advent of biologic DMARDs and, most recently, small-molecule signalling inhibitors. Novel strategies for the use of such agents have also transformed outcomes, as have multidisciplinary nonpharmacological approaches to the management of rheumatic musculoskeletal disease including surgery, physical therapy and occupational therapy...
June 15, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28614506/health-work-portrait-of-community-workers-in-the-northeast-region-of-brazil
#9
Paloma Ribeiro Pires Simas, Isabela Cardoso de Matos Pinto
The aim of this study was to characterize the profile of community health workers in northeastern Brazil and aspects related to the management of their work. This is a cross-sectional study, which included 535 community agents who were distributed in 107 primary health units in northeastern Brazil. The data were extracted from eight blocks of questions related to the community agents' perceptions about social-demographic, economic and political factors; their contracts and remuneration; their evaluation as workers; their working conditions and their training...
June 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28606084/effect-of-oral-cinnamon-intervention-on-metabolic-profile-and-body-composition-of-asian-indians-with-metabolic-syndrome-a-randomized-double-blind-control-trial
#10
Sonal Gupta Jain, Seema Puri, Anoop Misra, Seema Gulati, Kalaivani Mani
BACKGROUND: Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched. METHODS: We investigated the effect of oral cinnamon consumption on body composition and metabolic parameters of Asian Indians with metabolic syndrome. In this 16-week double blind randomized control trial, 116 individuals with metabolic syndrome were randomized to two dietary intervention groups, cinnamon [6 capsules (3 g) daily] or wheat flour [6 capsules (2...
June 12, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28603460/cultivating-the-multiple-sclerosis-workforce-of-the-future
#11
Gabriele C DeLuca, Guy Buckle, Irene Cortese, Jennifer S Graves, June Halper, Scott D Newsome, Nancy Sicotte, Corey C Ford
Multiple sclerosis (MS) is a complex neurologic disorder that affects people with ever-changing needs. The MS health-care field has entered an era of exponential knowledge growth in which better understanding of the immunologic dysregulation of the disease has translated into an expanding array of treatment options. It is estimated that, if it has not already, within the next decade the demands of a growing MS patient population will outstrip the number of professionals dedicated to the management of this chronic, lifelong disease...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28600699/a-single-visit-multidisciplinary-model-for-managing-patients-with-mutations-in-moderate-and-high-risk-genes-in-a-community-practice-setting
#12
Michael P O'Leary, Bryan S Goldner, Sridevi Abboy, Philip D Mercado, Hong Yoon Plurad
The introduction of screening for multiple high and moderate risk mutations in genes has resulted in a complex approach to patient care involving multiple disciplines. We sought to describe the feasibility of a single visit multidisciplinary approach to the management of patients with an identified high/moderate risk gene mutation. Patients who presented to our community hospital over a 1-year period who were found to have a high/moderate risk genetic mutation on a screening panel were referred to the High Risk Genetic Clinic...
June 9, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28597066/effects-of-fat-grafting-containing-stem-cells-in-microstomia-and-microcheilia-derived-from-systemic-sclerosis
#13
Oskar Blezien, Francesco D'Andrea, Giovanni Francesco Nicoletti, Giuseppe Andrea Ferraro
BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease with multisystem involvement, dominated by a general fibrosis. The early stage of the disease is associated with progressive damage to microcirculation, particularly in the respiratory tract, the gastrointestinal tract and skin. The face assumes a typical appearance characterized by microstomia (reduction of mouth opening) and microcheilia (thinning of the lips). These conditions cause a considerable reduction in performance status of patients...
June 8, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28596087/enabling-the-sustainable-faecal-sludge-management-service-delivery-chain-a-case-study-of-dense-settlements-in-kigali-rwanda
#14
Jean Baptiste Akumuntu, Uta Wehn, Martin Mulenga, Damir Brdjanovic
The lack of access to basic sanitation is a global concern and alarmingly prevalent in low- and middle- income countries. In the densely populated settlements of these countries, on-site sanitation systems are usually the only feasible option because dwellers there have no sewers in place to connect to. Using on-site sanitation facilities results in an accumulation of faecal sludge which needs to be properly managed to ensure the well-being of the users as well as the surrounding environment. Unfortunately, often the conditions for faecal sludge management (FSM) within dense settlements are adverse and thus hamper sustainable FSM...
May 23, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28594529/concussion-in-sports-what-do-orthopaedic-surgeons-need-to-know
#15
Patrick J Cahill, Christian Refakis, Eileen Storey, William C Warner
A concussion is a relatively common sports-related injury that affects athletes of all ages. Although not expected to replace sports medicine physicians and neurologists with regard to the management of concussions, orthopaedic surgeons, particularly those who are fellowship-trained in sports medicine, must have a current knowledge base of what a concussion is, how a concussion is diagnosed, and how a concussion should be managed. Orthopaedic surgeons should understand the pathophysiology, assessment, and management of concussion so that they have a basic comprehension of this injury that is at the forefront of the academic literature and North American media...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28588110/clinicians-perspectives-of-parental-decision-making-following-diagnosis-of-a-severe-congenital-anomaly-a-qualitative-study
#16
Robyn Lotto, Lucy K Smith, Natalie Armstrong
OBJECTIVE: To explore clinicians' perspectives on supporting parents' decision-making following diagnosis of a severe congenital anomaly, and how this is shaped by current policy. METHODS: This paper reports data collated as part of a larger project examining parents' decision-making following antenatal diagnosis. The focus of this paper is the data arising from semistructured interviews conducted with 18 clinicians, with findings further supported by data generated from consultations between clinicians and parents...
June 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28587663/parent-experiences-and-information-needs-relating-to-procedural-pain-in-children-a-systematic-review-protocol
#17
Allison Gates, Kassi Shave, Robin Featherstone, Kelli Buckreus, Samina Ali, Shannon Scott, Lisa Hartling
BACKGROUND: There exist many evidence-based interventions available to manage procedural pain in children and neonates, yet they are severely underutilized. Parents play an important role in the management of their child's pain; however, many do not possess adequate knowledge of how to effectively do so. The purpose of the planned study is to systematically review and synthesize current knowledge of the experiences and information needs of parents with regard to the management of their child's pain and distress related to medical procedures in the emergency department...
June 6, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28587511/diagnosis-and-management-of-clinical-reasoning-difficulties-part-ii-clinical-reasoning-difficulties-management-and-remediation-strategies
#18
Marie-Claude Audétat, Suzanne Laurin, Valérie Dory, Bernard Charlin, Mathieu R Nendaz
Part II of this AMEE Guide provides a detailed overview of the main difficulties in clinical reasoning, including the cues to look out for in clinical supervision, the root causes of each difficulty and targeted remediation strategies. Specific challenges and issues related to the management of clinical reasoning difficulties will also be discussed.
June 7, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28583233/myxofibrosarcoma-of-the-maxillary-sinus
#19
Anni Wong, Richard Chan Woo Park, Neena M Mirani, Jean Anderson Eloy
BACKGROUND: Myxofibrosarcoma (MFS) is a common sarcoma in the extremities of older individuals but is extremely uncommon in the head and neck region. Diagnosis may be challenging but is critical to the management of the patient. We discuss the radiographic and histopathologic characteristics of this destructive tumor. The distinguishing features of MFS and its differential diagnosis are reviewed to familiarize the managing otolaryngologist with this rare entity. METHODS: A 61-year-old woman presents with a 6-week history of severe left facial pain and left eye pain...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28577453/stabilization-of-arsenic-and-fluoride-bearing-spent-adsorbent-in-clay-bricks-preparation-characterization-and-leaching-studies
#20
Vineet Kumar Rathore, Prasenjit Mondal
The presence of arsenic and fluoride in groundwater has been observed throughout the world. Many technologies have been developed by various research groups in order to tackle this problem. Adsorption has emerged as one of the best possible technique for the removal of arsenic, fluoride and many other pollutants from drinking water. Although a considerable amount of work has been published on the adsorptive removal of arsenic and fluoride, the area related to the management of spent adsorbent is not well explored...
May 31, 2017: Journal of Environmental Management
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