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https://www.readbyqxmd.com/read/29343312/fecal-microbiota-transplant-for-multidrug-resistant-organism-decolonization-administered-during-septic-shock
#1
Srinivasa Nithin Gopalsamy, Amy Sherman, Michael H Woodworth, Joseph D Lutgring, Colleen S Kraft
No abstract text is available yet for this article.
January 18, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29336763/methicillin-resistant-staphylococcus-aureus-in-a-trauma-population-does-decolonization-prevent-infection
#2
Robert A Maxwell, Chasen A Croft, C Buddy Creech, Isaac Thomsen, Nicole Soper, Laura E Brown, Vicente A Mejia, Benjamin W Dart, Donald E Barker
The purpose of this study was to determine if a decolonization regimen reduces the frequency of methicillin-resistant Staphylococcus aureus (MRSA) infections and if colonization isolates are genetically related to subsequent infectious strains. Trauma patients admitted to the intensive care unit with positive MRSA nasal swabs were randomized to either daily chlorhexidine gluconate (CHG) baths and mupirocin (MUP) ointment to the nares or soap and water baths and placebo ointment for five days. Nasal swabs performed at the end of treatment and invasive MRSA infections during the remaining hospitalization were compared with the original nasal isolate via polymerase chain reaction for genetic relatedness as well as CHG and MUP resistance genes...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29336224/treatment-of-a-klebsiella-pneumoniae-kpc-cellulitis-and-gut-decolonization-with-ceftazidime-avibactam-in-a-migrant-from-libya
#3
Novella Carannante, Carlo Pallotto, Mariano Bernardo, Giovanni Di Caprio, Carlo Tascini
KPC-producing Klebsiella pneumoniae (KPC-Kp) is nowadays a global concern. Ceftazidime/avibactam is the most promising novel antibiotic combination available at the moment. We describe the case of a migrant with no risk factors for an infection due to multidrug resistant bacteria. He suffered from a KPC-Kp cellulitis and was treated with a ceftazidime/avibactam-meropenem-fosfomycin combination that not only eradicated the infection but also decontaminated his gut. Ceftazidime/avibactam-based treatment can be useful also in decontamination procedures...
January 16, 2018: Journal of Chemotherapy
https://www.readbyqxmd.com/read/29319509/prevalence-influencing-factors-antibiotic-resistance-toxin-and-molecular-characteristics-of-staphylococcus-aureus-and-mrsa-nasal-carriage-among-diabetic-population-in-the-united-states-2001-2004
#4
Jialing Lin, Yang Peng, Chan Bai, Ting Zhang, Haoqu Zheng, Xiaojie Wang, Jiaping Ye, Xiaohua Ye, Ying Li, Zhenjiang Yao
Diabetic population were reported more likely to suffer carriage and infection with Staphylococcus aureus (S. aureus) and methicillin-resistant Staphylococcus aureus (MRSA) than non-diabetic population. We aim to elucidate the prevalence and characteristics of S. aureus and MRSA nasal carriage among diabetic population in the United States National Health and Nutrition Examination Survey, 2001-2004. Univariate analyses were conducted using Chi-square test, Fisher's exact probability test or student t test, as appropriate...
December 4, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/29311241/cessation-from-smoking-improves-innate-host-defense-and-clearance-of-experimentally-inoculated-nasal-s-aureus
#5
Amy L Cole, Mary Schmidt-Owens, Ashley C Beavis, Christine F Chong, Patrick M Tarwater, James Schaus, Michael G Deichen, Alexander M Cole
Staphylococcus aureus (SA) nasal carriage is transient in most humans and usually benign, but dissemination of SA to extranasal sites causes the majority of clinical infections, and SA is a major cause of serious infections in the U.S. A better understanding of innate nasal decolonization mechanisms is urgently needed, as are relevant models for studying SA clearance. Here, we screened a population of healthy smokers for nasal SA carriage, and compared participants' abilities to clear experimentally applied nasal SA before and after completion of a smoking cessation program...
January 8, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29306970/preoperative-decolonization-to-reduce-infections-in-urgent-lower-extremity-repairs
#6
Daniel S Urias, Merin Varghese, Thomas Simunich, Shawna Morrissey, Russell Dumire
PURPOSE: Medical implants and surgical site infections (SSIs) can be a burden on both patients and healthcare systems with a significant rise in morbidity, mortality and costs. Preoperatively, our practice of a chlorohexidine gluconate (CHG) washcloth bath or solution shower was supplemented with nasal painting using povidone-iodine skin and nasal antiseptic (PI-SNA). We sought to measure the effectiveness in reducing SSIs in patients undergoing repair of lower extremity fractures. METHODS: A retrospective review of trauma patients undergoing orthopedic operations conducted at Conemaugh Memorial Medical Center from 10/1/2012 through 9/30/2016...
January 6, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29290149/body-mapping-to-explore-reproductive-ethno-physiological-beliefs-and-knowledge-of-contraception-in-timor-leste
#7
Heather Julie Wallace, Susan McDonald, Suzanne Belton, Agueda Isolina Miranda, Eurico da Costa, Livio da Conceicao Matos, Helen Henderson, Angela Taft
Maternal mortality remains a significant public health challenge for Timor-Leste. Although access to quality family planning measures may greatly reduce such deaths, consideration of indigenous perceptions, and how they influence reproductive health decision-making and behavior, is crucial if health services are to provide initiatives that are accepted and helpful in improving reproductive health outcomes. We aimed to demonstrate that body mapping is an effective method to traverse language and culture to gain emic insights and indigenous worldviews...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29283668/mindful-activism-embracing-the-complexities-of-international-border-crossings
#8
Kathryn L Norsworthy
I am one of many psychologists from the minority world, or Global North, who regularly travel to the Global South, or majority world, to engage in activist research and practice. Drawing on postcolonial and decolonial frameworks, this testimonio discusses tensions and complexities that arise in these transnational border crossings, particularly given the current internationalization movement in U.S. psychology. A testimonio is a first-person narrative of experiences with oppression, resilience, and empowerment, that can "re-script history ...
December 2017: American Psychologist
https://www.readbyqxmd.com/read/29281844/-decolonization-of-health-care-workers-in-a-neonatal-intensive-care-unit-carrying-a-methicillin-susceptible-staphylococcus-aureus-isolate
#9
Annika Richter, Ines Eder, Brigitte König, Bettina Lutze, Arne C Rodloff, Ulrich H Thome, Melanie Weiss, Iris F Chaberny
BACKGROUND: In 2016, an increased rate of methicillin-susceptible Staphylococcus aureus colonization was detected on a neonatal intensive care unit at the Leipzig University Hospital. Typing results showed a predominant spa-type t091. Considering nosocomial clustering, several infection prevention measures (e. g. intensified standard precautions, single-occupancy room, cohorted patients, continuing education of staff) were introduced, including staff screening followed by decolonization of colonized health care workers...
December 27, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29262416/consensus-on-wound-antisepsis-update-2018
#10
Axel Kramer, Joachim Dissemond, Simon Kim, Christian Willy, Dieter Mayer, Roald Papke, Felix Tuchmann, Ojan Assadian
Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, systemic antibiotic therapy is required in case the infection spreads. If applied preventively, the Wounds-at-Risk Score allows an assessment of the risk for infection and thus appropriateness of the indication...
December 21, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/29246843/tonsillectomy-for-persistent-mrsa-carriage-in-the-throat-description-of-three-cases
#11
Renske REMLabordus-van Helvoirt, Miranda MMLvan Rijen, Peter Pvan Wijngaarden
In several countries, including the Netherlands, a search and destroy policy is part of the standard of care. Due to this policy and restrictive use of antibiotics the prevalence of MRSA carrier state and infections in The Netherlands is among the lowest in the world. In the Netherlands health care workers with a MRSA carrier state are not allowed to carry out work involving direct patient care. This means that treatment failure can have major implications for their working career. Despite repeated treatments according to guidelines, eradication of MRSA fails in a minority of cases...
December 12, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29234644/prophylaxis-with-nasal-decolonization-in-patients-submitted-to-total-knee-and-hip-arthroplasty-systematic-review-and-meta-analysis
#12
REVIEW
David Sadigursky, Henrique Santos Pires, Saulo Américo Caldas Rios, Francisco Luiz Borja Rodrigues Filho, Gustavo Castro de Queiroz, Mateus Lemos Azi
Despite the evolution of the total knee and hip arthroplasty surgery, high postoperative complication rates in the short and long term still persist. Infection is one of the most challenging complications; due to its gravity and treatment difficulties, prophylaxis protocols have been created to decrease its incidence. The objective of this study was to evaluate the impact of the prophylaxis protocol for methicillin-resistant Staphylococcus aureus decolonization of the nares in patients previously identified by swab cultures, who were to be submitted to a total joint arthroplasty...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29191610/incidence-and-prevention-of-infective-endocarditis-and-bacteraemia-after-transcatheter-aortic-valve-implantation-in-a-french-university-hospital-a-retrospective-study
#13
M Gallouche, G Barone-Rochette, P Pavese, B Bertrand, G Vanzetto, H Bouvaist, I Pierre, D Schmitt, J Fauconnier, Y Caspar, C Recule, R Picot-Guéraud, J P Stahl, M R Mallaret, C Landelle
Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) is a rare but severe complication. Among 326 patients who underwent TAVI in Grenoble Alpes university hospital, 6 (1.8%) IE cases and 11 (3.4%) bacteraemia cases were identified. No EI was linked to the intervention; one was due to Staphylococcus aureus despite a screening and targeted decolonization strategy. This underscores the need for randomized studies to evaluate benefit and cost-effectiveness of this policy.
November 27, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29190327/control-of-healthcare-and-community-associated-mrsa-recent-progress-and-persisting-challenges
#14
Andrew Henderson, Graeme R Nimmo
Background: Healthcare adapted meticillin-resistant Staphylococcus aureus (MRSA) has spread to hospitals around the world over 50 years. More recently, other strains of MRSA have emerged with the ability to spread in the community and infect otherwise healthy individuals. Morbidity and mortality associated with MRSA remains high and its control in both the healthcare and community setting has proven challenging. Sources of data: Pubmed (Medline). Areas of agreement: The use of targeted screening and decolonization, hand hygiene and antimicrobial stewardship is supported by the most robust studies, though many studies have implemented bundles for effective healthcare-associated (HA)-MRSA control...
November 28, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/29188407/colonialist-pasts-and-afrosurrealist-futures-decolonizing-race-and-doctorhood-in-doctor-who
#15
Saljooq M Asif, Cindy Saenz
Originally premiering in 1963, the BBC television series Doctor Who has long been criticized for essentializing colonial scenarios and failing to address issues of race and post-colonial realities. As a white male with the privilege to explore time and space, the titular Doctor stands in contrast to his human companion Martha Jones, a Black woman who represents the first and only main character in the show to be a medical professional of color. The relationship between the Doctor and Martha inherently demands an exploration of the meaning of doctorhood...
November 29, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/29184755/dissemination-of-high-level-mupirocin-resistant-cc22-mrsa-iv-in-saxony
#16
Stefan Monecke, Antje Ruppelt-Lorz, Elke Müller, Annett Reissig, Alexander Thürmer, Anna C Shore, David C Coleman, Ralf Ehricht, Lutz Jatzwauk
Mupirocin is used for eradicating methicillin-resistant S. aureus (MRSA) in nasal colonization. A plasmid-borne gene, mupA, is associated with high-level mupirocin resistance. Despite the fact that, among all MRSA from a tertiary care center in the German state of Saxony, the prevalence of mupA, encoding high-level mupirocin resistance, was approximately 1% over a 15-year period from 2000-2015, a sharp increase to nearly 20% was observed in 2016/2017. DNA microarray profiling revealed that this was due to the dissemination of a variant of CC22-MRSA-IV ("Barnim Epidemic Strain" or "UK-EMRSA-15"), which, in addition to mecA, harbors mupA, aacA-aphD, qacA, and - in most isolates - erm(C)...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/29182046/decolonizing-scoping-review-methodologies-for-literature-with-for-and-by-indigenous-peoples-and-the-african-diaspora-dialoguing-with-the-tensions
#17
Lori A Chambers, Randy Jackson, Catherine Worthington, Ciann L Wilson, Wangari Tharao, Nicole R Greenspan, Renee Masching, Valérie Pierre-Pierre, Tola Mbulaheni, Marni Amirault, Patrick Brownlee
This article summarizes our deepened understanding of decolonizing research with, for, and by Indigenous peoples and peoples of African descent that emerged from conducting a scoping review of the methodological literature and reflecting on our review process. Although our review identified decolonizing methodologies as a promising approach, we questioned if our scoping review process engaged in decolonizing knowing. To unpack the epistemological tensions between decolonizing knowing and Western ways of doing scoping reviews, we engaged in individual and collective reflective processes- dialoguing with the tensions-moving from individual immersion in the literature to transformative dialogues among the team...
January 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29154409/sensitive-topics-missing-data-and-refusal-in-social-network-studies-an-ethical-examination
#18
Erin Rose Ellison, Regina Day Langhout
We describe our ethics-driven process of addressing missing data within a social network study about accountability for racism, classism, sexism, heterosexism, cis-sexism, ableism, and other forms of oppression among social justice union organizers. During data collection, some would-be participants did not return emails and others explicitly refused to engage in the research. All refusals came from women of color. We faced an ethical dilemma: Should we continue to seek participation from those who had not yet responded, with the hopes of recruiting more women of color from within the network so their perspectives would not be tokenized? Or, should we stop asking those who had been contacted multiple times, which would compromise the social network data and analysis? We delineate ways in which current discussions of the ethics of social network studies fell short, given our framework and our community psychology (CP) values...
November 20, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/29120455/manipulating-the-microbiome-evolution-of-a-strategy-to-prevent-s-aureus-disease-in-children
#19
D F Khamash, A Voskertchian, A M Milstone
Hospitalized infants have the highest rates of invasive Staphylococcus aureus disease of any population and infection control strategies such as decolonization have been insufficient. For decades, researchers began studying the microbiome in search of new prevention strategies. The resident microbiota was found to be closely associated with susceptibility and at times, resistance to S. aureus colonization. The evolution of nucleic acid based techniques has enhanced our understanding of the complex relationship between the nasal microbiota and S...
November 9, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29111353/clinical-factors-predicting-persistent-carriage-of-klebsiella-pneumoniae-carbapenemase-producing-carbapenem-resistant-enterobacteriaceae-among-patients-with-known-carriage
#20
Y K Kim, S A Song, J N Lee, M Oh, K M Jo, H-J Kim, J H Lee, J Park, H-J Jang, H-K Kim, S Kiem
BACKGROUND: Information on the natural duration of carbapenem-resistant Enterobacteriaceae (CRE) carriage and factors associated with persistence of carriage is limited. AIM: To evaluate the clinical variables associated with persistent carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing CRE. METHODS: Data for patients admitted between June 2015 and December 2016 who were identified as KPC-producing CRE carriers by either rectal swabs or clinical cultures were reviewed retrospectively...
October 27, 2017: Journal of Hospital Infection
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