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https://www.readbyqxmd.com/read/28212676/genetic-diversity-and-selection-of-three-nuclear-genes-in-schistosoma-japonicum-populations
#1
Yaqi Li, Mingbo Yin, Qunfeng Wu, Donald P McManus, David Blair, Hongyan Li, Bin Xu, Xiaojin Mo, Zheng Feng, Wei Hu
BACKGROUND: The blood fluke, Schistosoma japonicum still causes severe disease in China, the Philippines and Indonesia. Although there have been some studies the molecular epidemiology of this persistent and harmful parasite, few have explored the possibility and implications of selection in S. japonicum populations. METHODS: We analyzed diversity and looked for evidence of selection at three nuclear genes (SjIpp2, SjFabp and SjT22.6) in 13 S. japonicum populations...
February 17, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28211758/life-cycle-host-utilization-and-ecological-fitting-for-invasive-lancet-liver-fluke-dicrocoelium-dendriticum-emerging-in-southern-alberta-canada
#2
Bradley van Paridon, John S Gilleard, Douglas D Colwell, Cameron P Goater
The expansion of parasite distributions outside of their native host and geographical ranges has occurred repeatedly over evolutionary time. Contemporary examples include emerging infectious diseases (EID's), many of which pose threats to human, domestic animal, and wildlife populations. Theory predicts that parasites with complex life cycles will be rare as EID's due to constraints imposed by host specialization at each life-cycle stage. In contrast to predictions of this theory, we report 2 new intermediate hosts in the 3-host life cycle of the liver fluke Dicrocoelium dendriticum in Cypress Hills Provincial Park, Alberta, Canada...
February 17, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28198451/elevated-prevalence-of-helicobacter-species-and-virulence-factors-in-opisthorchiasis-and-associated-hepatobiliary-disease
#3
Raksawan Deenonpoe, Eimorn Mairiang, Pisaln Mairiang, Chawalit Pairojkul, Yaovalux Chamgramol, Gabriel Rinaldi, Alex Loukas, Paul J Brindley, Banchob Sripa
Recent reports suggest that Opisthorchis viverrini serves as a reservoir of Helicobacter and implicate Helicobacter in pathogenesis of opisthorchiasis-associated cholangiocarcinoma (CCA). Here, 553 age-sex matched cases and controls, 293 and 260 positive and negative for liver fluke O. viverrini eggs, of residents in Northeastern Thailand were investigated for associations among infection with liver fluke, Helicobacter and hepatobiliary fibrosis. The prevalence of H. pylori infection was higher in O. viverrini-infected than uninfected participants...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28186433/production-of-monoclonal-antibody-against-excretory-secretory-antigen-of-fasciola-hepatica-and-evaluation-of-its-efficacy-in-the-diagnosis-of-fascioliasis
#4
Samaneh Abdolahi Khabisi, Bahador Sarkari, Abdolali Moshfe, Sedigheh Jalali
Parasitological methods are not helpful for the diagnosis of fascioliasis in acute and invasive periods of the disease. Detection of coproantigens seems to be a suitable alternative approach in the diagnosis of fascioliasis. The present study aimed to develop a reliable antigen detection system, using monoclonal antibodies raised against excretory-secretory (ES) antigen of Fasciola hepatica, for the diagnosis of fascioliasis. Fasciola adult worms were collected from the bile ducts of infected animals. Species of the fluke was determined by polymerase chain reaction-restriction fragment length polymorphism (RFLP-PCR)...
February 10, 2017: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
https://www.readbyqxmd.com/read/28180910/-ambiguous-hepatic-mass-and-fever-after-stay-in-turkey
#5
J Mueller, S Dagenbach, B Riecken, C Klinger
We report the case of a 76-year old female patient with a hepatic mass after staying in eastern Turkey. There were no indices for malignancy or an infection with Echinococcus or Entamoeba histolytica. Finally we diagnosed a Fascioliasis (liver fluke) and cured the patient successfully.
February 8, 2017: Der Internist
https://www.readbyqxmd.com/read/28177299/development-of-an-improved-wearable-device-for-core-body-temperature-monitoring-based-on-the-dual-heat-flux-principle
#6
Jingjie Feng, Congcong Zhou, Cheng He, Yuan Li, Xuesong Ye
In this paper, a miniaturized wearable core body temperature (CBT) monitoring system based on the dual heat flux (DHF) principle was developed. By interspersing calcium carbonate powder in PolyDimethylsiloxane (PDMS), a reformative heat transfer medium was produced to reduce the thermal equilibrium time. Besides, a least mean square (LMS) algorithm based active noise cancellation (ANC) method was adopted to diminish the impact of ambient temperature fluctuations. Theoretical analyses, finite element simulation, experiments on a hot plate and human volunteers were performed...
February 8, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28165868/effect-of-the-filamentous-fungus-mucor-circinelloides-on-the-development-of-eggs-of-the-rumen-fluke-calicophoron-daubneyi-paramphistomidae
#7
Fabià  N Arroyo, Josà  à  Ngel Hernà  Ndez, Cristiana Filipa Cazapal-Monteiro, Josà  Pedreira, Jaime Sanchà  S, à  Ngel Romasanta, Rita Sã  Nchez-Andrade, Adolfo Paz-Silva, Marà  A Sol Arias
Ruminants infected by Paramphistomidae flukes shed eggs in the feces, which pass through different stages in the environment until the infective stages (metacercariae) are reached. The activity of the soil fungus Mucor circinelloides on the development of eggs of the rumen fluke Calicophoron daubneyi was presently tested with 3 probes, i.e., in Petri plates, feces and an aqueous environment (tubes). The effect of the fungus was assessed by recording the numbers of undeveloped, non-viable and embryonated eggs...
February 6, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28162101/fasciola-hepatica-infections-in-cattle-and-the-freshwater-snail-galba-truncatula-from-dakhla-oasis-egypt
#8
W M Arafa, A I Hassan, S A M Snousi, Kh M El-Dakhly, P J Holman, T M Craig, S M Aboelhadid
Infection by Fasciola species was investigated in seven districts of Dakhla Oasis, Egypt, through abattoir inspection of cattle livers for adult worms and sedimentation of faecal samples from local cattle to detect Fasciola eggs. In addition, lymnaeid snails collected from the study area were examined microscopically for developmental stages of Fasciola spp. Abattoir inspection revealed that 51 out of 458 cattle livers (11.1%) contained adult flukes, which were identified morphologically as Fasciola hepatica...
February 6, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28152102/anthelmintic-potential-of-thymoquinone-and-curcumin-on-fasciola-gigantica
#9
Rizwan Ullah, Abdur Rehman, Mohd Faraz Zafeer, Lubna Rehman, Yasir A Khan, M A Hannan Khan, Shahper N Khan, Asad U Khan, S M A Abidi
Fasciolosis an economically important global disease of ruminants in the temperate and tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a potential zoonotic threat. In India alone it causes huge losses to stakeholders. Anthelmintics including triclabendazole have been used to control this menace but the emerging resistance against the available compounds necessitates identification of novel and alternative therapeutic measures involving plant derived natural compounds for their anthelmintic potential...
2017: PloS One
https://www.readbyqxmd.com/read/28145217/rumen-fluke-calicophoron-daubneyi-on-welsh-farms-prevalence-risk-factors-and-observations-on-co-infection-with-fasciola-hepatica
#10
Rhys Aled Jones, Peter M Brophy, E Sian Mitchell, Hefin Wyn Williams
Reports of Calicophoron daubneyi infecting livestock in Europe have increased substantially over the past decade; however, there has not been an estimate of its farm level prevalence and associated risk factors in the UK. Here, the prevalence of C. daubneyi across 100 participating Welsh farms was recorded, with climate, environmental and management factors attained for each farm and used to create logistic regression models explaining its prevalence. Sixty-one per cent of farms studied were positive for C...
February 2017: Parasitology
https://www.readbyqxmd.com/read/28143561/transcriptomic-responses-of-water-buffalo-liver-to-infection-with-the-digenetic-fluke-fasciola-gigantica
#11
Fu-Kai Zhang, Xiao-Xuan Zhang, Hany M Elsheikha, Jun-Jun He, Zhao-An Sheng, Wen-Bin Zheng, Jian-Gang Ma, Wei-Yi Huang, Ai-Jiang Guo, Xing-Quan Zhu
BACKGROUND: Fasciola gigantica, the tropical liver fluke, infects buffaloes in Asian and African countries and causes significant economic losses and poses public health threat in these countries. However, little is known of the transcriptional response of buffaloes to infection with F. gigantica. The objective of the present study was to perform the first transcriptomic analysis of buffalo liver infected by F. gigantica. Understanding the mechanisms that underpin F. gigantica infection in buffaloes will contribute to our ability to control this parasite...
February 1, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28131660/light-and-scanning-electron-microscopy-study-of-in%C3%A2-vitro-effects-of-artesunate-in-newly-excysted-metacercariae-of-echinostoma-paraensei-trematoda-digenea
#12
Joyce G R Souza, Eduardo J Lopes Torres, Juberlan S Garcia, Ana Paula N Gomes, Rosangela Rodrigues-Silva, Arnaldo Maldonado, José Roberto Machado-Silva
Chemotherapy of food-borne trematodes relies on two drugs, praziquantel and tricabendazole, and there is growing interest in finding alternative therapies. Plant oil extracts have long been used in traditional Chinese medicine as sources of bioactive compounds with antiparasitic activity. Species of the genus Echinostoma are used as good models to test effective compounds against food-borne trematodes. This study evaluated the anthelmintic activity of crude artesunate extracts in vitro on newly excysted metacercariae of Echinostoma paraensei by light and scanning electron microscopy (SEM)...
January 25, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28127341/parasitic-burdens-egg-output-hemathologic-and-biochemical-changes-in-naturally-infected-lambs-with-dicrocoelium-dendriticum
#13
Hadi Samadie, Gholamreza Mohammadi, Mohammad Heidarpour, Mohammad Azizzadeh, Mohsen Maleki, Hassan Borji
BACKGROUND: We investigated the variations of heamathologic and biochemical parameters with different parasitic burdens and the correlation between fecal egg counts and fluke number in livers of sheep naturally infected with Dicrocoelium dendriticum. METHODS: In order to detect excretion of D. dendriticum eggs, fecal samples from 120 sheep of different age groups were collected individually at slaughterhouse in Neyshabur County in Razavi Khorasan Province during December 2013 - October 2014...
July 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28116053/vertebrate-defense-against-parasites-interactions-between-avoidance-resistance-and-tolerance
#14
Ines Klemme, Anssi Karvonen
Hosts can utilize different types of defense against the effects of parasitism, including avoidance, resistance, and tolerance. Typically, there is tremendous heterogeneity among hosts in these defense mechanisms that may be rooted in the costs associated with defense and lead to trade-offs with other life-history traits. Trade-offs may also exist between the defense mechanisms, but the relationships between avoidance, resistance, and tolerance have rarely been studied. Here, we assessed these three defense traits under common garden conditions in a natural host-parasite system, the trematode eye-fluke Diplostomum pseudospathaceum and its second intermediate fish host...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28108370/application-of-environmental-dna-analysis-for-the-detection-of-opisthorchis-viverrini-dna-in-water-samples
#15
Hiroki Hashizume, Megumi Sato, Marcello Otake Sato, Sumire Ikeda, Tippayarat Yoonuan, Surapol Sanguankiat, Tiengkham Pongvongsa, Kazuhiko Moji, Toshifumi Minamoto
Opisthorchiasis, which can lead to cholangiocarcinoma in cases of chronic infection, is a major public health problem in Southeast Asian countries. The trematode, Opisthorchis viverrini, is the causative agent of the disease. Accurate and rapid monitoring of O. viverrini is crucial for disease prevention and containment. Therefore, in this study we sought to develop a novel species-specific real-time PCR assay for detecting O. viverrini using environmental DNA (eDNA). The diagnostic sensitivity of the newly developed real-time PCR assay was similar to that of the traditional PCR assay for 50 fecal samples collected in Lao PDR (21 and 19 samples were positive by real-time PCR and traditional PCR, respectively)...
January 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28105582/-control-of-opisthorchis-viverrini-infection-for-cholangiocarcinoma-prevention
#16
Y Buisson
The International Agency for Research on Cancer (IARC) has classified two liver flukes as carcinogenic to humans (Group 1): Opisthorchis viverrini in 1994 and Clonorchis sinensis in 2009. This review is focused on O. viverrini, the most studied of these two trematodes, which infects nearly 10 million people in Southeast Asia. The life cycle involves two intermediate hosts living in fresh water: a snail of the genus Bithynia and a ciprinid fish. The definitive hosts (human, cat, dog) become infected by ingesting raw fish containing metacercariae, the infective stage of the parasite...
January 19, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28104494/thoughts-on-interactions-between-pgrmc1-and-diverse-attested-and-potential-hydrophobic-ligands
#17
REVIEW
Michael A Cahill, Amy E Medlock
Progesterone Receptor Membrane Component 1 (PGRMC1) is located in many different subcellular locations with many different attested and probably location-specific functions. PGRMC1 was recently identified in the mitochondrial outer membrane where it interacts with ferrochelatase, the last enzyme in the heme synthetic pathway. It has been proposed that PGRMC1 may act as a chaperone to shuttle newly synthesized heme from the mitochondrion to cytochrome P450 (cyP450) enzymes. Here we consider potential roles that PGRMC1 may play in transferring heme, and other small hydrophobic ligands such as cholesterol and steroids, between the hydrophobic compartment of the membrane lipid bilayer interior to aqueous proteins, and perhaps to the membranes of other organelles...
January 16, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28095013/the-tipping-point-of-perceived-change-asymmetric-thresholds-in-diagnosing-improvement-versus-decline
#18
Ed O'Brien, Nadav Klein
Change often emerges from a series of small doses. For example, a person may conclude that a happy relationship has eroded not from 1 obvious fight but from smaller unhappy signs that at some point "add up." Everyday fluctuations therefore create ambiguity about when they reflect substantive shifts versus mere noise. Ten studies reveal an asymmetry in this first point when people conclude "official" change: people demand less evidence to diagnose lasting decline than lasting improvement, despite similar evidential quality...
February 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28094661/diagnosis-of-pancreatic-disease-in-feline-platynosomosis
#19
Liza S Köster, Linda Shell, Jennifer Ketzis, Sreekumari Rajeev, Oscar Illanes
Objectives Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal proximity of the pancreas, it is possible that platynosomosis could cause pancreatitis. The objective of this study was to determine whether platynosomosis, a commonly diagnosed parasitic disease in cats on St Kitts, has any association with pancreatic disease. Methods To investigate this possibility, the pancreas of free-roaming cats with naturally acquired platynosomosis were evaluated via ultrasound, serum concentrations of feline pancreatic lipase (fPL), cobalamin, folate and feline trypsin-like immunoreactivity (fTLI) and histopathology...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28093542/disease-burden-of-dengue-in-the-philippines-adjusting-for-underreporting-by-comparing-active-and-passive-dengue-surveillance-in-punta-princesa-cebu-city
#20
Eduardo A Undurraga, Frances E Edillo, Jonathan Neil V Erasmo, Maria Theresa P Alera, In-Kyu Yoon, Francisco M Largo, Donald S Shepard
Dengue virus (DENV) is a serious threat to public health. Having reliable estimates of the burden of dengue is important to inform policy and research, but surveillance systems are not designed to capture all symptomatic DENV infections. We derived the rate of reporting of dengue by comparing active surveillance of symptomatic DENV infections in a prospective community-based seroepidemiological cohort study (N = 1008) of acute febrile illness in Punta Princesa, Cebu City, Philippines, with passive surveillance data from the Cebu City Health Department...
January 16, 2017: American Journal of Tropical Medicine and Hygiene
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