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adrenalin vs norepinephrin

Jiří Baláš, David Giles, Leona Chrastinová, Kateřina Kárníková, Jan Kodejška, Alžběta Hlaváčková, Ladislav Vomáčko, Nick Draper
The aim of this study was to examine the effect of alterations in potential lead fall distance on the hormonal responses of rock climbers. Nine advanced female climbers completed two routes while clipping all (PRO-all) or half (PRO-½) of the fixed points of protection. Venous blood samples were analysed for total catecholamines, noradrenaline (norepinephrine), adrenaline (epinephrine), dopamine, lactate, cortisol and serotonin. Differences between the two conditions pre, immediately post and 15 min post climbing were assessed using a 2 × 3 repeated measures ANOVA...
July 11, 2016: Journal of Sports Sciences
Pär I Johansson, John Bro-Jeppesen, Jesper Kjaergaard, Michael Wanscher, Christian Hassager, Sisse R Ostrowski
OBJECTIVE: Sympathoadrenal activation and endothelial damage are hallmarks of acute critical illness. This study investigated their association and predictive value in patients resuscitated from out-of-hospital cardiac arrest (OHCA). METHODS: Post-hoc analysis of patients included at a single site in The Targeted Temperature Management at 33 degrees versus 36 degrees after Cardiac Arrest (TTM) trial. The main study reported similar outcomes with targeting 33 versus 36 degrees...
2015: PloS One
Andrej Tillinger, Martina Novakova, Olga Krizanova, Richard Kvetnansky, Jaromir Myslivecek
The left and right ventricles fulfill different role in heart function. Here we compare chamber specific changes in local catecholamine concentrations; gene expression and the receptor protein amount of all three β-adrenoceptors (β-AR) in rat right heart ventricles exposed to acute (1 session) and repeated (7 sessions) immobilization stress (IMMO) vs. previously observed changes in left ventricles. Density of muscarinic receptors as main cardio-inhibitive receptors was also measured. In the right ventricles, noradrenaline and adrenaline were increased...
2014: General Physiology and Biophysics
E Suzuki, T Ohya, R Ito, T Matsumoto, K Kitagawa
This study examined the physiological responses to cold stimulus during intermittent high-intensity exercise simulating on-snow alpine ski training. 7 male alpine skiers performed intermittent high-intensity exercises composed of 4 bouts of cycling exercise at 140% VO 2max intensity for 30 s with 10-min rests on a cycle ergometer in cold (1°C) and control (22°C) conditions. The subjects wore racing suits, middle layers and half pants designed for alpine skiers. Rectal temperature and mean skin temperature were lower in the cold condition than in the control condition (36...
May 2014: International Journal of Sports Medicine
Alfred Nimmerichter, Johann Holdhaus, Lars Mehnen, Claudia Vidotto, Markus Loidl, Alan R Barker
Limited research has suggested that acute exposure to negatively charged ions may enhance cardio-respiratory function, aerobic metabolism and recovery following exercise. To test the physiological effects of negatively charged air ions, 14 trained males (age: 32 ± 7 years; VO2max: 57 ± 7 mL min(-1) kg(-1)) were exposed for 20 min to either a high-concentration of air ions (ION: 220 ± 30 × 10(3) ions cm(-3)) or normal room conditions (PLA: 0.1 ± 0.06 × 10(3) ions cm(-3)) in an ionization chamber in a double-blinded, randomized order, prior to performing: (1) a bout of severe-intensity cycling exercise for determining the time constant of the phase II VO2 response (τ) and the magnitude of the VO2 slow component (SC); and (2) a 30-s Wingate test that was preceded by three 30-s Wingate tests to measure plasma [adrenaline] (ADR), [nor-adrenaline] (N-ADR) and blood [lactate] (B(Lac)) over 20 min during recovery in the ionization chamber...
September 2014: International Journal of Biometeorology
Maria Jiménez-Jiménez, Alma García-Escalona, Alejandra Martín-López, Raquel De Vera-Vera, Joaquin De Haro
OBJECTIVE: The purpose of this study was to investigate the music therapy (MT) effect in levels of intraoperative anxiety in patients undergoing crossectomy with stripping of the great saphenous vein and to assess the efficacy, safety, and feasibility of this alternative therapy as a complement of standard intraoperative care. MATERIAL AND METHODS: The study is a simple blind, controlled, parallel groups, prospective randomized clinical trial. Patients were allocated by means of randomized controlled sampling...
September 2013: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
Feng J He, Jiafu Li, Graham A Macgregor
BACKGROUND: A reduction in salt intake lowers blood pressure (BP) and, thereby, reduces cardiovascular risk. A recent meta-analysis by Graudal implied that salt reduction had adverse effects on hormones and lipids which might mitigate any benefit that occurs with BP reduction. However, Graudal's meta-analysis included a large number of very short-term trials with a large change in salt intake, and such studies are irrelevant to the public health recommendations for a longer-term modest reduction in salt intake...
2013: Cochrane Database of Systematic Reviews
A B Abderrahmane, J Prioux, I Mrizek, K Chamari, Z Tabka, A Bouslama, H Zouhal
The effect of recovery mode (Active [AR] vs. Passive [PR]) on plasma catecholamine (Adrenaline [A] and Noradrenaline [NA]) responses to maximal exercise (Exemax) was studied during interval training (IT). 24 male subjects (21.1±1.1 years) were randomly assigned to a control group (CG, n=6), AR training group (ARG, n=9) or PR group (PRG, n=9). ARG and PRG participated in an IT program 3 times a week for 7 weeks. Before and after training, maximal oxygen uptake (VO2max) and maximal aerobic velocity (MAV) were measured...
August 2013: International Journal of Sports Medicine
Peter Adolfsson, Staffan Nilsson, Kerstin Albertsson-Wikland, Bengt Lindblad
BACKGROUND: Physical activity is a critical component in the care of diabetes. Although it offers health benefits it presents challenges. OBJECTIVE: To investigate differences between adolescent boys and girls with type 1 diabetes and healthy controls in terms of maximal work capacity (VO(2) max) and hormonal response to physical exercise of different intensities. SUBJECTS: Twelve individuals (six boys and six girls; age 14-19 yr, pubertal stage 4-5) with type 1 diabetes (duration, 6...
December 2012: Pediatric Diabetes
Pär I Johansson, Anne Marie Sørensen, Anders Perner, Karen-Lise Welling, Michael Wanscher, Claus F Larsen, Sisse R Ostrowski
OBJECTIVE: High patient age is a strong predictor of poor outcome in trauma patients. The present study investigated the effect of age on mortality and biomarkers of sympathoadrenal activation, tissue, endothelial, and glycocalyx damage, coagulation activation/inhibition, fibrinolysis, and inflammation in trauma patients at admission. DESIGN: Prospective observational study. SETTING: Single level I trauma center. PATIENTS: Eighty adult trauma patients (≥18 yrs) who met criteria for full trauma team activation and had an arterial cannula...
June 2012: Critical Care Medicine
Laurie Isacco, David Thivel, Anne Meddahi Pelle, Hassane Zouhal, Martine Duclos, Pascale Duche, Nathalie Boisseau
Oral contraception (OC) and energy intake may play a role in fuel selection during exercise. The aim of this study was to investigate the effect of OCs (OC+ vs. OC-) in fed and fasting conditions on substrate oxidation and metabolic and hormonal responses in women during exercise. Substrate oxidation (respiratory exchange ratio and lipid and carbohydrates oxidation rates), metabolic (glycerol, free fatty acids (FFA), and glucose), and hormonal (insulin, adrenaline, and noradrenaline) responses were determined in 21 women: 10 regularly menstruating women (OC-) and 11 women using OCs (OC+: low-dose monophasic pill; ethinyl estradiol ≤ 30 µg) during 45 min at 65% of maximal oxygen consumption in fasting and postprandial states...
August 2012: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Todd M Larabee, Kirsten Y Liu, Jenny A Campbell, Charles M Little
OBJECTIVES: To review the literature addressing whether the use of vasopressors improves outcomes in patients who suffer cardiac arrest. METHODS: Databases were searched using the terms: "(adrenaline or noradrenaline or vasopressor) and (heart arrest or cardiac arrest) and therapy". Inclusion criteria were human studies, controlled trials, meta-analysis or case series. Exclusion criteria were articles with no abstract, abstract-only citations without accompanying article, non-English abstracts, vasopressor studies without human clinical trials, case reports, reviews, and articles addressing traumatic arrest...
August 2012: Resuscitation
Olli-Pekka Piira, Pirjo E Mustonen, Johanna A Miettinen, Heikki V Huikuri, Mikko P Tulppo
OBJECTIVES. Emotional excitement may trigger serious cardiovascular (CV) events. Our objective was to compare the changes in potential surrogate markers of CV events in patients with coronary artery disease (CAD) during emotional excitement and exercise. DESIGN. Fifty-three enthusiastic ice-hockey spectators with stable CAD attended the Finnish national ice-hockey play-off matches and a maximal bicycle exercise. Plasma catecholamines, endothelin-1, interleukin-6, and markers of platelet activation and blood coagulation were determined before and during the match and before and after the exercise...
February 2012: Scandinavian Cardiovascular Journal: SCJ
Pär I Johansson, Jakob Stensballe, Lars S Rasmussen, Sisse R Ostrowski
OBJECTIVE: To investigate the association between markers of acute endothelial glycocalyx degradation, inflammation, coagulopathy, and mortality after trauma. BACKGROUND: Hyperinflammation and acute coagulopathy of trauma predict increased mortality. High catecholamine levels can directly damage the endothelium and may be associated with enhanced endothelial glycocalyx degradation, evidenced by high circulating syndecan-1. METHODS: Prospective cohort study of trauma patients admitted to a Level 1 Trauma Centre in 2003 to 2005...
August 2011: Annals of Surgery
Izumi Kawagoe, Keiko Tajima, Masanori Kanai, Snoko Kimura, Hiromasa Mitsuhata
BACKGROUND: Remifentanil recently comes to be used for intraoperative analgesia instead of epidural anesthesia in gynecological surgery. It seems to offer the same stability in vital signs, but stress response during remifentanil anesthesia has not been evaluated. Therefore, we compared remifentanil anesthesia with epidural anesthesia regarding stress hormones. METHODS: Fifty-one patients scheduled for surgery were randomized into two groups (epidural group: E and remifentanil group: R)...
April 2011: Masui. the Japanese Journal of Anesthesiology
Andreas W Prengel, Ulf Linstedt
AIM OF THE STUDY: In comparison to adrenaline, administration of vasopressin increases adrenal gland perfusion, but decreases catecholamine plasma concentrations when compared to saline placebo. We directly compared the effects of adrenaline with different doses of vasopressin on adrenal gland perfusion, and noradrenaline plasma concentrations during CPR. METHODS: Twenty-one pigs received either 0.2 mg kg(-1) adrenaline (n = 7), 0.2 U kg(-1) vasopressin (n = 7), or 0...
May 2011: Resuscitation
Marzo E Da Silva-Grigoletto, Juan M Fernández, Clodoaldo A de Sá, José R Gómez-Puerto, Diana Vaamonde, Francisco Pérez-Jiménez
The addition of fructose (F) to a glucose (G) supplement may modify the metabolic response during exercise; however, its effect on perceived exertion (PE) and its influence on postprandial metabolism have not been jointly studied in different types of exercise. This study sought to assess the acute effects of F addition to a G supplement on PE and on the postprandial metabolic response during a single bout of either strength exercise (SE) or endurance exercise (EE). Twenty physically trained men ingested an oral dose of G or GF 15 minutes before starting a 30-minute session of SE (10 sets of 10 repetitions of half squat) or EE (cycling)...
December 2010: Journal of Strength and Conditioning Research
Yasushige Shingu, Suguru Kubota, Satoru Wakasa, Noriyoshi Ebuoka, Daisuke Mori, Tomonori Ooka, Tsuyoshi Tachibana, Yoshiro Matsui
OBJECTIVE: Although several risk factors for postoperative atrial fibrillation (AF) have been proposed, it remains the most common complication after cardiac surgery, even in low-risk patients. There is still no single reliable and reproducible parameter for predicting AF, and no standardized recommendation exists for this issue. Electromechanical delay (excitation-contraction coupling delay) is the time delay from the electrical activation to the actual systolic motion, and it reflects abnormality in calcium-handling proteins, which is considered one mechanism of postoperative AF...
May 2011: European Journal of Cardio-thoracic Surgery
C M McHenry, S J Hunter, M T McCormick, C F Russell, M G Smye, A B Atkinson
The aim of this study is to review the experience of the clonidine suppression test in a regional endocrine centre and to compare the diagnostic sensitivity and specificity using various previous published criteria. The design used is retrospective study. The subjects include 56 patients in whom clonidine suppression tests had been performed from 1995 to 2000: 15 with phaeochromocytoma and 41 patients in whom the diagnosis was excluded using a combination of biochemical testing, abdominal computed tomography scanning and clinical follow-up...
July 2011: Journal of Human Hypertension
Sandra Eifert, Helmut Mair, Anne-Laure Boulesteix, Eckehard Kilian, Martin Adamczak, Bruno Reichart, Peter Lamm
The number of percutaneous coronary interventions (PCI) prior to coronary artery bypass grafting (CABG) increased drastically during the last decade. Patients are referred for CABG with more severe coronary pathology, which may influence postoperative outcome. Outcomes of 200 CABG patients, collected consecutively in an observational study, were compared (mean follow-up: 5 years). Group A (n = 100, mean age 63 years, 20 women) had prior PCI before CABG, and group B (n = 100, mean age 66, 20 women) underwent primary CABG...
2010: Vascular Health and Risk Management
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