Osama Alsheikh, Sultan Alzaaidi, Jose M Vargas, Eman Al-Sharif, Mohammed Alrajeh, Mohammad A AlSemari, Abdulrahman Alhommadi, Anoud Alsaati, Nouf Aljwaiser, Eman Alshahwan, Mona Abdulhafiz, Rashad Elsayed, Wolfgang G K Müller-Lierheim
PURPOSE: The aim of the HYLAN A study was to investigate if symptoms and/or signs of patients suffering from severe dry eye disease (DED) in Saudi Arabia can be improved by substituting individually optimized artificial tear therapy by high molecular weight hyaluronan (HMWHA) eye drops. METHODS: The HYLAN M study, a multicenter prospective randomized open-label study, was performed in 11 centers in eight countries. Patients suffering from severe DED were electronically randomized in two parallel arms...
October 2021: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society