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Drosophlia melanogaster

T B Friedman, D H Johnson
The appearance of urate oxidase activity in the Malpighian tubules of Drosophlia melanogaster is synchronized with the time of emergence of the imago from the puparium. A developmental clock within the Malpighian tubules specifies the time of appearances of urate oxidase activity.
July 29, 1977: Science
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