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https://www.readbyqxmd.com/read/29327147/post-operative-catheterization-interventions-at-the-site-of-surgery-an-application-of-the-crisp-scoring-system
#1
Katie Mowers, Toby Rockefeller, David Balzer, Ramzi Nicolas, Shabana Shahanavaz
Catheter-based interventions in the early post-operative period are performed with caution due to concerns for increased procedural risk, particularly across fresh suture lines. The recently published CRISP scoring system provides prospective risk stratification based on pre-procedural criterion. In an effort to refine the assessment of risk in patients undergoing post-operative catheter-based interventions, the predicted risk of an adverse event based on CRISP scores was compared to actual adverse event rates...
January 12, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29317610/enrichment-of-schizophrenia-heritability-in-both-neuronal-and-glia-cell-regulatory-elements
#2
Katherine E Tansey, Matthew J Hill
Genome-wide association studies have identified over 100 robust risk loci for schizophrenia with thousands of variants mediating genetic heritability, the majority of which reside in non-coding regions. Analytical approaches have shown this heritability is strongly enriched at variants within regulatory elements identified from human post-mortem brain tissue. However, bulk post-mortem brain tissue has a heterogeneous cell composition, making biological interpretations difficult. We sought to refine the cell types mediating schizophrenia heritability by separating neuronal and glial signals using data from: (1) NeuN-sorted post-mortem brain and (2) cell culture systems...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29317115/post-procedural-n-terminal-pro-brain-natriuretic-peptide-predicts-one-year-mortality-after-transcatheter-aortic-valve-implantation
#3
Nelson Carlos Vale, Rui Campante Teles, Sérgio Madeira, João Brito, Manuel Sousa Almeida, Tiago Nolasco, Joao Abecasis, Gustavo Rodrigues, João Carmo, Maria Furstenau, Regina Ribeiras, José Pedro Neves, Miguel Mendes
INTRODUCTION: Natriuretic peptides are ubiquitously used for diagnosis, follow-up and prognostic assessment in various heart conditions. N-terminal pro-brain natriuretic peptide (NT-proBNP) correlates with aortic stenosis severity, however its significance after transcatheter aortic valve implantation (TAVI) is not well established. AIM: We aimed to assess the prognostic value of NT-proBNP at one year in patients undergoing TAVI. METHODS: This single-center retrospective analysis included 151 patients in whom both baseline and one-month post-procedure NT-proBNP were measured, from 206 consecutive patients undergoing TAVI between November 2008 and December 2014...
January 6, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29316474/spinal-versus-general-anesthesia-for-lumbar-spine-surgery-in-high-risk-patients-perioperative-hemodynamic-stability-complications-and-costs
#4
Michael Finsterwald, Marco Muster, Mazda Farshad, Andrea Saporito, Muriel Brada, José A Aguirre
OBJECTIVE: More stable perioperative hemodynamic conditions, lower costs and a lower perioperative complication rate were reported in young healthy patients undergoing lumbar spine surgery in spinal anesthesia (SA) compared to general anesthesia (GA). However, the benefits of SA in high risk patients (ASA≥II suffering from cardiovascular and/or pulmonary pathologies) undergoing this surgery are unclear. Our objective was to analyze whether SA leads to an improved perioperative hemodynamic stability and to a more cost-effective management compared to GA in high risk patients undergoing this surgery...
January 6, 2018: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29315462/aprepitant-as-a-fourth-antiemetic-prophylactic-strategy-in-high-risk-patients-a-double-blind-randomized-trial
#5
L C de Morais, A M Sousa, G F Flora, T R Grigio, G M N Guimarães, H A Ashmawi
BACKGROUND: Post-operative nausea and vomiting (PONV) is one of the most important causes of patient discomfort after laparoscopic surgeries despite the use of a multimodal pharmacological approach. This study assessed whether the addition of aprepitant to a multimodal regimen would further decrease the incidence of PONV in high-risk patients. METHODS: Apfel-score three or four patients, scheduled for laparoscopic procedures to treat abdominal or pelvic cancer, were randomized to receive oral starch (control group) or 80 mg of oral aprepitant (treatment group) before induction of anaesthesia in a double-blind study...
January 7, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29314751/emergency-airway-and-ventilator-procedures-for-community-based-home-care-staff-validation-of-an-educational-program
#6
Ann Marie Ramsey, Sarah Brennan, Adam Stricker, Kurt Riek, Dana Brown, Rachel Gurtowsky, Julie Sturza, Amy Goldstein Filbrun
BACKGROUND: Children discharged home with tracheostomy and chronic mechanical ventilator support are at high risk for complications and adverse events. Private duty nursing and home respiratory care services are a critical support necessary for successful discharge. The literature suggests that there are opportunities for home care staff (HCS) to improve upon the skills necessary to assess and intervene in an emergency thereby increasing the likelihood of improving long-term outcomes...
January 4, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29312849/do-not-resuscitate-status-as-an-independent-risk-factor-for-patients-undergoing-surgery-for-hip-fracture
#7
Ethan Y Brovman, Andrew J Pisansky, Anair Beverly, Angela M Bader, Richard D Urman
AIM: To determine morbidity and mortality in hip fracture patients and also to assess for any independent associations between Do-Not-Resuscitate (DNR) status and increased post-operative morbidity and mortality in patients undergoing surgical repair of hip fractures. METHODS: We conducted a propensity score matched retrospective analysis using de-identified data from the American College of Surgeons' National Surgical Quality Improvement Project (ACS NSQIP) for all patients undergoing hip fracture surgery over a 7 year period in hospitals across the United States enrolled in the ACS NSQIP with and without DNR status...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29302726/which-patients-require-extended-thromboprophylaxis-after-colectomy-modeling-risk-and-assessing-indications-for-post-discharge-pharmacoprophylaxis
#8
Eliza W Beal, Dmitry Tumin, Jeffery Chakedis, Erica Porter, Dimitrios Moris, Xu-Feng Zhang, Mark Arnold, Alan Harzman, Syed Husain, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: Given the conflicting nature of reported risk factors for post-discharge venous thromboembolism (VTE) and unclear guidelines for post-discharge pharmacoprophylaxis, we sought to determine risk factors for 30-day post-discharge VTE after colectomy to predict which patients will benefit from post-discharge pharmacoprophylaxis. METHODS: Patients who underwent colectomy in the American College of Surgeons National Surgical Quality Improvement Project Participant Use Files from 2011 to 2015 were identified...
January 4, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29301713/the-coronary-artery-disease-reporting-and-data-system-cad-rads-prognostic-and-clinical-implications-associated-with-standardized-coronary-computed-tomography-angiography-reporting
#9
Joe X Xie, Ricardo C Cury, Jonathon Leipsic, Matthew T Crim, Daniel S Berman, Heidi Gransar, Matthew J Budoff, Stephan Achenbach, Bríain Ó Hartaigh, Tracy Q Callister, Hugo Marques, Ronen Rubinshtein, Mouaz H Al-Mallah, Daniele Andreini, Gianluca Pontone, Filippo Cademartiri, Erica Maffei, Kavitha Chinnaiyan, Gilbert Raff, Martin Hadamitzky, Joerg Hausleiter, Gudrun Feuchtner, Allison Dunning, Augustin DeLago, Yong-Jin Kim, Philipp A Kaufmann, Todd C Villines, Benjamin J W Chow, Niree Hindoyan, Millie Gomez, Fay Y Lin, Erica Jones, James K Min, Leslee J Shaw
OBJECTIVES: This study sought to assess clinical outcomes associated with the novel Coronary Artery Disease-Reporting and Data System (CAD-RADS) scores used to standardize coronary computed tomography angiography (CTA) reporting and their potential utility in guiding post-coronary CTA care. BACKGROUND: Clinical decision support is a major focus of health care policies aimed at improving guideline-directed care. Recently, CAD-RADS was developed to standardize coronary CTA reporting and includes clinical recommendations to facilitate patient management after coronary CTA...
January 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29295772/differences-in-post-operative-outcome-between-conversion-and-primary-total-hip-arthroplasty
#10
Charles D Qin, Mia M Helfrich, David W Fitz, Mark A Oyer, Kevin D Hardt, David W Manning
BACKGROUND: The demand for conversion of prior hip surgery to total hip arthroplasty (conversion THA) is likely to increase as a function of increasing US hip fracture burden in addition to its application in managing other conditions. Thus, outcome analysis is warranted to better inform value-based reimbursement schemes in the era of bundled payments. METHODS: Via Current Procedural Terminology codes, the National Surgical Quality Improvement Project data files were queried for all patients who underwent primary THA and conversion of previous hip surgery to THA from 2005 to 2014...
November 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29288858/risk-factors-associated-with-meningitis-after-neurosurgery-operation-a-retrospective-cohort-study-in-a-chinese-hospital
#11
Shengsen Chen, An Cui, Kangkang Yu, Chong Huang, Mengqi Zhu, Mingquan Chen
OBJECTIVE: Meningitis is a serious complication occurring after neurosurgical operations, which can result in severe morbidity and high mortality. This retrospective cohort study aimed to determine the risk factors of postoperative meningitis in a large clinical center of Neurosurgery in China. METHODS: Patients who underwent neurosurgeries between January 2014 and December 2015 were selected and 1016 cases were included the final analysis. On the basis of propensity scores, 84 post-operative meningitis patients were successfully matched to the 84 patients without post-operative meningitis...
December 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29288141/functional-reach-depression-scores-and-number-of-medications-are-associated-with-number-of-falls-in-people-with-chronic-stroke
#12
Aqeel M Alenazi, Mohammed M Alshehri, Shaima Alothman, Jason Rucker, Kari Dunning, Linda D'Silva, Patricia M Kluding
BACKGROUND: Falls are a common adverse event among people with stroke. Previous studies investigating risk of falls after stroke have relied primarily on retrospective fall history ranging from 6-12 months recall, with inconsistent findings. OBJECTIVES: To identify factors and balance assessment tools that are associated with number of falls in individuals with chronic stroke. DESIGN: Secondary analysis of a randomized clinical trial. SETTING: Multisite academic and clinical institutions...
December 26, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29277793/retzius-sparing-robotic-assisted-radical-prostatectomy-associated-with-less-bladder-neck-descent-and-better-early-continence-outcome
#13
Li-Wen Chang, Sheng-Chun Hung, Ju-Chuan Hu, Kun-Yuan Chiu
BACKGROUND/AIM: We attempted to evaluate the association of early continence outcome of Retzius-sparing robotic assisted radical prostatectomy (RARP) and bladder neck descent with postoperative cystography. PATIENTS AND METHODS: From November 2014 to December 2015, 30 patients with prostate cancer who received Retzius-sparing LRP/ RARP were compared to 30 patients that received retropubic approach RARP with propensity score matching analysis. Cystogram was used to evaluate the bladder neck descent using the bladder neck to pubic symphysis (BNPS) ratio and the continence state was evaluated...
January 2018: Anticancer Research
https://www.readbyqxmd.com/read/29276990/bright-light-and-oxygen-therapies-decrease-delirium-risk-in-critically-ill-surgical-patients-by-targeting-sleep-and-acid-base-disturbances
#14
Sirimas Potharajaroen, Sookjaroen Tangwongchai, Thavatchai Tayjasanant, Thammasak Thawitsri, George Anderson, Michael Maes
This study examined the effects of bright light therapy (BLT) on the incidence of delirium in post-operative patients admitted to a surgical intensive care unit (SICU) and delineates risk and protective factors. We included 62 patients in a single-blind, randomized controlled study. The intervention group was treated with care as usual plus BLT for three consecutive days. Delirium was diagnosed by DSM-5 criteria with the Confusion Assessment Method-Intensive Care Unit (CAM-ICU). Risk factors for delirium were measured, including the APACHE II score, Insomnia Severity Index (ISI), as well as hematocrit and bicarbonate levels...
December 18, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29274841/preoperative-risk-score-and-prediction-of-long-term-outcomes-after-hepatectomy-for-intrahepatic-cholangiocarcinoma
#15
Kazunari Sasaki, Georgios A Margonis, Nikolaos Andreatos, Fabio Bagante, Matthew Weiss, Carlotta Barbon, Irinel Popescu, Hugo P Marques, Luca Aldrighetti, Shishir K Maithel, Carlo Pulitano, Todd W Bauer, Feng Shen, George A Poultsides, Oliver Soubrane, Guillaume Martel, B Groot Koerkamp, Alfredo Guglielmi, Endo Itaru, Federico N Aucejo, Timothy M Pawlik
BACKGROUND: Accurate prediction of prognosis for patients with intrahepatic cholangiocarcinoma(ICC) remains a challenge. We sought to define a preoperative risk tool to predict long-term survival following resection of ICC. METHODS: Patients who underwent hepatectomy for ICC at one of 16 major hepatobilliary centers between 1990-2015 were identified. Clinico-pathological data were analyzed and a prognostic model was developed based on the regression beta-coefficients on data in training set...
December 21, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29273046/development-and-validation-of-a-patient-reported-questionnaire-assessing-systemic-therapy-induced-diarrhea-in-oncology-patients
#16
Michelle Lui, Daniela Gallo-Hershberg, Carlo DeAngelis
BACKGROUND: Systemic therapy-induced diarrhea (STID) is a common side effect experienced by more than half of cancer patients. Despite STID-associated complications and poorer quality of life (QoL), no validated assessment tools exist to accurately assess STID occurrence and severity to guide clinical management. Therefore, we developed and validated a patient-reported questionnaire (STIDAT). METHODS: The STIDAT was developed using the FDA iterative process for patient-reported outcomes...
December 22, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29260311/body-mass-index-hip-function-and-surgeon-volume-are-independent-predictors-of-dislocation-an-analysis-of-4334-total-hip-replacements
#17
John Annan, Nick Clement, Gavin J Macpherson, Ivan J Brenkel, James A Ballantyne, Edward Dunstan
The aim of this study was to identify pre-operative and intra-operative factors that are predictive of dislocation following primary total hip replacement (THR). Data were prospectively collected for a consecutive series of 4334 THRs undertaken over a 14-year period. Ninety-eight (2.3%) of the 4334 patients had one or more dislocation post-operatively. A body mass index (BMI) of ≥ 35 (p < 0.001), a Harris Hip Score (HHS) of ≤ 41 (p < 0.001) and a low-volume surgeon (p < 0.001), which was defined as performing fewer than 43 THRs per annum, were identified as independent predictors of dislocation using logistic regression analysis...
December 19, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29242503/comparison-of-intrafascial-and-non-intrafascial-radical-prostatectomy-for-low-risk-localized-prostate-cancer
#18
Zhankui Zhao, Haizhou Zhu, Honglian Yu, Qingsheng Kong, Chengjuan Fan, Lin Meng, Chuanxin Liu, Xiegang Ding
In this meta-analysis study, we compared the oncological and functional outcomes of intrafascial radical prostatectomy (IFRP) with non-intrafascial radical prostatectomy (NIFRP) in the treatment of patients with low risk localized prostate cancer (PCa). Relevant articles were identified by searching PubMed, EMBASE, Cochrane Library, Ovid, and the ISI Web of Knowledge databases. A total of 2096 patients were included from 7 eligible studies. Results of the pooled data showed that the oncological outcomes including gleason score, positive surgical margin and biochemical free survival rates were similar between the two groups...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29240012/surgical-treatment-of-chronic-elbow-dislocation-allowing-early-range-of-motion-operative-technique-and-clinical-results
#19
Duane R Anderson, Justin M Haller, Lucas A Anderson, Samuel Hailu, Abebe Chala, Shawn W O'Driscoll
OBJECTIVES: Describe the surgical treatment and patient outcomes of chronic elbow dislocations. DESIGN: Retrospective review SETTING:: Two tertiary referral centers. PATIENTS/PARTICIPANTS: All patients with surgically treated chronic elbow dislocation with no associated articular fracture from January 2009 - January 2015. INTERVENTION: Review of patient demographics, injury chronicity, surgical technique, and patient outcomes...
December 6, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29222664/anatomical-reconstruction-to-treat-acromion-fractures-following-reverse-shoulder-arthroplasty
#20
Florian Hess, Ralph Zettl, Daniel Smolen, Christoph Knoth
PURPOSE: Scapular fractures after reverse shoulder arthroplasty (RSA) are often associated with substantial shoulder impairment. Patient outcomes following either conservative or operative treatment have not been favourable, and consensus is lacking on the best treatment approach. We describe a technique for anatomic reconstruction of fractured lateral and basal acromion in patients at higher risk for diminished function or those for which conservative treatment has already failed. METHODS: Of the 95 patients who underwent RSA at our institution between December 2013 and December 2016, three had post-operative acromion fractures (type II)...
December 8, 2017: International Orthopaedics
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