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https://www.readbyqxmd.com/read/29777298/aortic-elasticity-deterioration-proves-intrinsic-abnormality-of-the-ascending-aorta-in-pediatric-turner-syndrome-unrelated-to-the-aortic-valve-morphology
#1
Christiane Pees, Julian A Heno, Gabriele Häusler, Diana-Alexandra Ertl, Talin Gulesserian, Ina Michel-Behnke
Turner syndrome (TS) is a common genetic disorder in females with high incidence of ascending aortic dilatation and even dissection occurring as early as in the second decade. Known risk factors (RF) are bicuspid aortic valves (BAV), coarctation of the aorta (CoA), and arterial hypertension. Since 10% of dissections occur in patients without RF, an intrinsic aortic wall abnormality has been postulated. This study aimed to investigate the elasticity of the ascending aorta as a surrogate marker of aortic wall texture...
May 18, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29777144/benefits-in-radical-mastectomy-protocol-a-randomized-trial-evaluating-the-use-of-regional-anesthesia
#2
Marcio Matsumoto, Eva M Flores, Pedro P Kimachi, Flavia V Gouveia, Mayra A Kuroki, Alfredo C S D Barros, Marcelo M C Sampaio, Felipe E M Andrade, João Valverde, Eduardo F Abrantes, Claudia M Simões, Rosana L Pagano, Raquel C R Martinez
Surgery is the first-line treatment for early, localized, or operable breast cancer. Regional anesthesia during mastectomy may offer the prevention of postoperative pain. One potential protocol is the combination of serratus anterior plane block (SAM block) with pectoral nerve block I (PECS I), but the results and potential benefits are limited. Our study compared general anesthesia with or without SAM block + PECS I during radical mastectomy with axillary node dissection and breast reconstruction using evaluations of pain, opioid consumption, side effects and serum levels of interleukin (IL)-1beta, IL-6 and IL-10...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776332/telnet-a-database-for-human-and-yeast-genes-involved-in-telomere-maintenance
#3
Delia M Braun, Inn Chung, Nick Kepper, Katharina I Deeg, Karsten Rippe
BACKGROUND: The ends of linear chromosomes, the telomeres, comprise repetitive DNA sequences in complex with proteins that protects them from being processed by the DNA repair machinery. Cancer cells need to counteract the shortening of telomere repeats during replication for their unlimited proliferation by reactivating the reverse transcriptase telomerase or by using the alternative lengthening of telomeres (ALT) pathway. The different telomere maintenance (TM) mechanisms appear to involve hundreds of proteins but their telomere repeat length related activities are only partly understood...
May 18, 2018: BMC Genetics
https://www.readbyqxmd.com/read/29774939/-feasibility-and-preliminary-technical-experience-of-single-incision-plus-one-port-laparoscopic-total-gastrectomy-combined-with-%C3%AF-shaped-esophagojejunal-anastomosis-in-surgical-treatment-of-gastric-cancer
#4
Guangsheng Du, Enlai Jiang, Yuan Qiu, Wensheng Wang, Shuai Wang, Yunbo Li, Ke Peng, Xiang Li, Hua Yang, Weidong Xiao
OBJECTIVE: To explore the feasibility, safety, and preliminary technical experience of single incision plus one port laparoscopic total gastrectomy combined with π-shaped esophagojejunal anastomosis (SILT-π) in the surgical treatment of gastric cancer. METHODS: Clinical data of 5 gastric cancer patients undergoing SILT-π operation at the Department of General Surgery, The Second Affiliated Hospital of the Army Medical University from August to October 2017 were retrospectively analyzed...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774087/severity-of-gastric-mucosal-atrophy-affects-the-healing-speed-of-post-endoscopic-submucosal-dissection-ulcers
#5
Taketo Otsuka, Mitsushige Sugimoto, Hiromitsu Ban, Toshiro Nakata, Masaki Murata, Atsushi Nishida, Osamu Inatomi, Shigeki Bamba, Akira Andoh
AIM: To investigate factors associated with the healing of endoscopic submucosal dissection (ESD)-induced ulcers. METHODS: We enrolled 132 patients with gastric tumors scheduled for ESD. Following ESD, patients were treated with daily lansoprazole 30 mg or vonoprazan 20 mg. Ulcer size was endoscopically measured on the day after ESD and at 4 and 8 wk. The gastric mucosa was endoscopically graded according to the Kyoto gastritis scoring system. We assessed the number of patients with and without a 90% reduction in ulcer area at 4 wk post-ESD and scar formation at 8 wk, and looked for risk factors for slower healing...
May 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29770954/the-relationship-between-physical-impairments-quality-of-life-and-disability-of-the-neck-and-upper-limb-in-patients-following-neck-dissection
#6
Elise M Gane, Steven M McPhail, Anna L Hatton, Benedict J Panizza, Shaun P O'Leary
PURPOSE: The purpose of this study was to examine the relationship between physical impairments, quality of life and disability in patients following neck dissection, with consideration of patient and clinical characteristics. METHODS: Cross-sectional study of patients < 5 years after neck dissection for head and neck cancer. Quality of life and self-reported disability were measured with the Neck Dissection Impairment Index, Quick Disabilities of the Arm, Shoulder and Hand, and Neck Disability Index...
May 16, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29770577/percutaneous-reduction-and-internal-fixation-for-monocondylar-fractures-of-tibial-plateau-a-systematic-review
#7
REVIEW
Heng-Rui Chang, Yi-Yang Yu, Lin-Lin Ju, Zhan-Le Zheng, Wei Chen, Ying-Ze Zhang
Instead of extensive dissection of soft tissue around the fracture site, percutaneous techniques have unique advantages in managing displaced fragments, including preservation of soft tissues, less blood loss, lower risk of complications, and earlier functional rehabilitation. However, there are few systematic reviews on the effects of percutaneous reduction and internal fixation (PRIF) for tibial plateau fractures. A systematic search of Cochrane, EMBASE, and MEDLINE databases was performed for all publicly available data in March 2017 regarding the use of PRIF in treating monocondylar tibial plateau fractures...
May 16, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29753622/acute-ischemic-dissection-of-an-s-shaped-carotid-artery-the-one-stop-value-of-using-a-detachable-solitaire-ab-stent
#8
Hongchao Shi, Jiankang Hou, Wanyin Shi, Jianping Gu
This study aimed to evaluate the efficacy and safety of endovascular repair using detachable Solitaire AB stents for acute ischemic dissection of "S"-shaped carotid arteries. From May 2015 to December 2016, a total of 127 patients with acute ischemic stroke (AIS) underwent endovascular treatment in our center. Among them, five AISs were due to acute dissection of an "S"-shaped carotid artery. Coexisting carotid embolism was identified in all five patients, who first underwent successful Solitaire AB stent-based retrieval of the embolism...
May 9, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29750981/comparison-of-endoscopic-submucosal-dissection-and-surgery-for-superficial-esophageal-squamous-cell-carcinoma-a-propensity-score-matched-analysis
#9
Yang Won Min, Hyuk Lee, Byeong Geun Song, Byung-Hoon Min, Hong Kwan Kim, Yong Soo Choi, Jun Haeng Lee, Na-Young Hwang, Keumhee C Carriere, Poong-Lyul Rhee, Jae J Kim, Jae Ill Zo, Young Mog Shim
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted for treating superficial esophageal squamous cell carcinoma (SESCC). However, long-term outcomes of ESD and esophagectomy for SESCC have not been compared. We compared the clinical outcomes of ESD and esophagectomy in a matched cohort. METHODS: Patients who underwent ESD and esophagectomy for SESCC were included. We selected SESCCs without obvious submucosal invasion from the surgical database by reviewing endoscopic images...
May 8, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29744579/circular-versus-linear-stapling-in-esophagojejunostomy-after-laparoscopic-total-gastrectomy-for-gastric-cancer-a-propensity-score-matched-study
#10
Noriaki Kyogoku, Yuma Ebihara, Toshiaki Shichinohe, Fumitaka Nakamura, Katsuhiko Murakawa, Takayuki Morita, Shunichi Okushiba, Satoshi Hirano
PURPOSE: We used propensity score matching to compare the complication rates after laparoscopic total gastrectomy (LTG) with esophagojejunostomy (EJS) performed using a circular or a linear stapler. METHODS: We retrospectively enrolled all patients who underwent curative LTG between November 2004 and March 2016. Patients were categorized into the circular and linear groups according to the stapler type used for the subsequent EJS. Patients in the groups were matched using the following propensity score covariates: age, sex, body mass index, American Society of Anesthesiologists physical status, extent of lymph node dissection, and Japanese Classification of Gastric Carcinoma stage...
May 9, 2018: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29739896/quantitative-proteomics-analysis-of-sporadic-medullary-thyroid-cancer-reveals-fn1-as-a-potential-novel-candidate-prognostic-biomarker
#11
Shaohua Zhan, Jinming Li, Tianxiao Wang, Wei Ge
BACKGROUND: Sporadic medullary thyroid cancer (MTC) is a rare neuroendocrine tumor. Currently, although the diagnosis of sporadic MTC is relatively simple, the need to discover novel candidate prognostic biomarkers for sporadic MTC and investigate the underlying mechanism involved in this rare disease is urgent. MATERIALS AND METHODS: We employed tandem mass tag-based liquid chromatography-mass spectrometry to identify and analyze differentially expressed proteins (DEPs) in sporadic MTC...
May 8, 2018: Oncologist
https://www.readbyqxmd.com/read/29734902/arteriography-and-histopathology-of-vascular-beds-in-traumatically-amputated-fingers
#12
Mehmet Ali Uysal, Deniz Gulabi, Güven Mete, Selçuk Tunalı, Arzu Avcı, Osman Arslan Bora
BACKGROUND: The success of replantation following traumatic amputation is determined by the quality of the vascular anastomoses. The purpose of this study was to assess the vascularity of injured arteries from traumatically amputated digits using arteriographic and histopathological analysis. METHODS: 25 amputated digits were included in the study. Crush and avulsion injuries were evaluated according to the Venkatramani classification. The amputated arteries were dissected under a microscope, and the arterial route determined with a transducer...
June 2018: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29730182/face-content-and-construct-validations-of-endoscopic-needle-injection-simulator-for-transurethral-bulking-agent-in-treatment-of-stress-urinary-incontinence
#13
Bilal Farhan, Tandis Soltani, Rebecca Do, Claudia Perez, Hanul Choi, Gamal Ghoniem
INTRODUCTION AND OBJECTIVES: Endoscopic injection of urethral bulking agents is an office procedure that is used to treat stress urinary incontinence secondary to internal sphincteric deficiency. Validation studies important part of simulator evaluation and is considered important step to establish the effectiveness of simulation-based training. The endoscopic needle injection (ENI) simulator has not been formally validated, although it has been used widely at University of California, Irvine...
May 2, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29725566/superficial-temporal-artery-middle-cerebral-artery-anastomosis-for-ischemic-stroke-due-to-dissection-of-the-intracranial-internal-carotid-artery-with-middle-cerebral-artery-extension
#14
Masashi Ikota, Gen Kusaka, Yuichi Tanaka
A 31-year-old man presented with a sudden-onset headache, right hemiparesis, and dysarthria on day 0 and was diagnosed with acute ischemic stroke due to dissection of the left intracranial internal carotid artery with middle cerebral artery extension. His symptoms progressed despite the institution of treatment, suggesting progression of the dissection. On day 5 after symptom onset, the patient underwent superficial temporal artery-middle cerebral artery anastomosis. No new ischemic stroke event occurred after surgery...
April 2018: NMC Case Report Journal
https://www.readbyqxmd.com/read/29720750/newer-regional-analgesia-interventions-fascial-plane-blocks-for-breast-surgeries-review-of-literature
#15
REVIEW
Rakesh Garg, Swati Bhan, Saurabh Vig
Surgical resection of the primary tumour with axillary dissection is one of the main modalities of breast cancer treatment. Regional blocks have been considered as one of the modalities for effective perioperative pain control. With the advent of ultrasound, newer interventions such as fascial plane blocks have been reported for perioperative analgesia in breast surgeries. Our aim is to review the literature for fascial plane blocks for analgesia in breast surgeries. The research question for initiating the review was 'What are the reported newer regional anaesthesia techniques (fascial plane blocks) for female patients undergoing breast surgery and their analgesic efficacy?...
April 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29720348/impact-of-adjuvant-radiotherapy-in-node-positive-prostate-cancer-patients-the-importance-of-patient-selection
#16
Firas Abdollah, Deepansh Dalela, Akshay Sood, Jacob Keeley, Shaheen Alanee, Alberto Briganti, Francesco Montorsi, James O Peabody, Mani Menon
Using institutional data, we have previously developed an algorithm to identify the optimal candidates for adjuvant radiotherapy (aRT) among men with pN1 prostate cancer (PCa) at radical prostatectomy (RP). This study aimed to test the external validity of our previous findings using a nationwide database while focusing on overall mortality as an endpoint. To this end, we identified 5498 pN1 PCa patients who were treated with RP, pelvic lymph node dissection, and androgen deprivation therapy with or without aRT, within the National Cancer Database, between 2004 and 2015...
April 29, 2018: European Urology
https://www.readbyqxmd.com/read/29720210/endoscopic-release-of-congenital-muscular-torticollis-with-radiofrequency-in-teenagers
#17
Jun-Liang Wang, Wei Qi, Yu-Jie Liu
BACKGROUND: Congenital muscular torticollis (CMT) is due to contracture of the sternocleidomastoid muscle which may cause activity limitations of the neck, tilt of the head, craniofacial asymmetry, and deformity of the skull. The authors present their experience of arthroscopic tight fibrous band release with radiofrequency in teenagers under local anesthesia and evaluate the clinical results. METHODS: A total of 69 patients who underwent arthroscopic release of CMT with radiofrequency under local anesthesia by a single surgeon could participate in this study...
May 3, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29719557/stent-reconstruction-of-carotid-tonsillar-loop-dissection-using-telescoping-peripheral-stents
#18
Benjamin M Zussman, Bradley A Gross, William J Ares, Cynthia L Kenmuir, Gregory M Weiner, David M Panczykowski, Ashutosh P Jadhav, Tudor G Jovin, Brian T Jankowitz
Background: Endovascular treatment options for internal carotid artery (ICA) dissection with tandem intracranial occlusion are evolving. We report 2 cases of stent reconstruction of carotid loop dissections. Methods: Two patients with symptomatic ICA dissections of true 360° tonsillar loops and tandem intracranial occlusions were treated with manual aspiration thrombectomy (MAT) and telescoping Zilver self-expanding peripheral stents. Patient demographics, clinical presentations, endovascular techniques, and clinical outcomes were reviewed...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29716729/prognostic-impact-of-lymphadenectomy-on-outcomes-of-sublobar-resection-for-stage-ia-non-small-cell-lung-cancer-%C3%A2-2-cm
#19
Jinlin Cao, Jinming Xu, Zhehao He, Ping Yuan, Sha Huang, Wang Lv, Jian Hu
OBJECTIVE: To investigate the prognostic impact of lymph node (LN) dissection on sublobar resection for stage IA non-small cell lung cancer (NSCLC) tumors ≤2 cm. METHODS: All patients who underwent sublobar resection for stage IA NSCLC tumors ≤2 cm were identified from the Surveillance, Epidemiology and End Results database. Patients were classified into no-LN dissection and LN dissection groups, and the latter was subclassified by the extent of LN dissection (1-3 regional LNs or ≥4 regional LNs)...
April 6, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29707807/clinical-outcomes-of-atherectomy-prior-to-percutaneous-coronary-intervention-a-comparison-of-outcomes-following-rotational-versus-orbital-atherectomy-coap-pci-study
#20
Perwaiz M Meraj, Evan Shlofmitz, Barry Kaplan, Rajiv Jauhar, Rajkumar Doshi
BACKGROUND: Because of the challenges in treating calcified coronary artery disease (CAD), lesion preparation has become increasingly important prior to percutaneous coronary intervention (PCI). Despite growing data for both rotational atherectomy (RA) and orbital atherectomy (OA), there have been no multicenter studies comparing the safety and efficacy of both. We sought to examine the clinical outcomes of patients with calcified CAD who underwent atherectomy. METHODS: A total of 39 870 patients from five tertiary care hospitals who had PCI from January 2011 to January 2017 were identified...
April 29, 2018: Journal of Interventional Cardiology
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