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https://www.readbyqxmd.com/read/29166460/microsurgical-treatment-of-basilar-tip-aneurysms-is-it-still-acceptable
#1
Felix Hendrik Pahl, Matheus Fernandes de Oliveira, José Marcus Rotta
OBJECTIVE: Basilar tip aneurysms (BTAs) have a complex anatomy, making them difficult to treat. We describe our surgical results for BTAs. METHODS: From 2004 to 2015 (12 years), a total of 25 small BTAs and two giant BTAs were treated in the Hospital do Servidor Público Estadual de São Paulo. RESULTS: In 23 patients harboring aneurysms positioned anteriorly or straight, all aneurysms were clipped (complete exclusion in all on follow-up angiography)...
October 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29164770/clinical-outcomes-of-patients-with-coronary-artery-aneurysm-after-the-first-generation-drug-eluting-stent-implantation
#2
Hyung Joon Joo, Cheol Woong Yu, RakKyeong Choi, Jinsik Park, Hyun Jong Lee, Je Sang Kim, Young Jin Choi, Jae Hyoung Park, Soon Jun Hong, Do Sun Lim
OBJECTIVES: We sought to investigate the long-term clinical outcomes of patients with coronary artery aneurysm (CAA) after drug-eluting stent (DES) implantation, compared with patients without CAA. BACKGROUND: CAA developed after DES implantation is a rare but associated with poor clinical outcome. METHODS: We retrospectively compared 78 patients with CAA after DES implantation with 269 patients without CAA who underwent DES implantation for complex lesions (controls)...
November 22, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29158449/induced-hypertension-for-delayed-cerebral-ischemia-after-aneurysmal-subarachnoid-hemorrhage-a-randomized-clinical-trial
#3
Celine S Gathier, Walter M van den Bergh, Mathieu van der Jagt, Bon H Verweij, Jan Willem Dankbaar, Marcella C Müller, Annemarie W Oldenbeuving, Gabriel J E Rinkel, Arjen J C Slooter
BACKGROUND AND PURPOSE: Induced hypertension is widely used to treat delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage, but a literature review shows that its presumed effectiveness is based on uncontrolled case-series only. We here report clinical outcome of aneurysmal subarachnoid hemorrhage patients with DCI included in a randomized trial on the effectiveness of induced hypertension. METHODS: Aneurysmal subarachnoid hemorrhage patients with clinical symptoms of DCI were randomized to induced hypertension or no induced hypertension...
November 20, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29152929/the-role-of-echocardiography-in-kawasaki-disease
#4
Brian W McCrindle, Barbara Cifra
Kawasaki disease (KD) is an acute, self-limited vasculitis affecting young children. It can result in coronary artery abnormalities in a significant proportion of patients, especially if the diagnosis is missed or treatment gets delayed. Echocardiography is the imaging modality of choice for detection of coronary artery abnormalities and assessment of myocardial function. It is also useful for characterization and risk stratification of patients with KD. Echocardiography should be performed at the time of diagnosis and then again at 1-2 weeks and 4-6 weeks after treatment, for uncomplicated cases who do not have significant coronary artery involvement...
November 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29152466/a-less-invasive-strategy-for-ruptured-cerebral-aneurysms-with-intracerebral-hematomas-endovascular-coil-embolization-followed-by-stereotactic-aspiration-of-hematomas-using-urokinase
#5
Sang Heum Kim, Tae Gon Kim, Min Ho Kong
Objective: Aneurysm clipping and simultaneous hematoma evacuation through open craniotomy is traditionally recommended for ruptured cerebral aneurysms accompanied by intracerebral or intrasylvian hemorrhages. We report our experience of adapting a less invasive treatment strategy in poor-grade patients with intracerebral or intrasylvian hemorrhages associated with ruptured cerebral aneurysms, where the associated ruptured cerebral aneurysms were managed by endovascular coil embolization, followed by stereotactic aspiration of hematomas (SRH) using urokinase...
June 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/29148905/serum-glucose-potassium-ratio-as-a-clinical-risk-factor-for-aneurysmal-subarachnoid-hemorrhage
#6
Yu Fujiki, Fumihiro Matano, Takayuki Mizunari, Yasuo Murai, Kojiro Tateyama, Kenta Koketsu, Asami Kubota, Shiro Kobayashi, Hiroyuki Yokota, Akio Morita
OBJECTIVE Aneurysmal subarachnoid hemorrhage (SAH) can result in poor outcomes, and biomarkers for predicting poor prognosis have not yet been established. The aim of this study was to clarify the significance of the serum glucose/potassium ratio for predicting the prognosis of aneurysmal SAH. METHODS The authors retrospectively reviewed the records of 565 patients with aneurysmal SAH between 2006 and 2016. The patient group comprised 208 men and 357 women (mean age 61.5 years, range 10-95 years). A statistical analysis was conducted of the clinical and laboratory risk factors of poor outcome, including the serum glucose/potassium ratio...
November 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29147735/reduction-of-metallic-artifacts-of-the-post-treatment-intracranial-aneurysms-effects-of-single-energy-metal-artifact-reduction-algorithm
#7
Yu-Ning Pan, Ge Chen, Ai-Jing Li, Zhao-Qian Chen, Xiang Gao, Yi Huang, Bradley Mattson, Shan Li
PURPOSE: This study evaluated the quality of computed tomography (CT) and CT angiography images generated using the single-energy metal artifact reduction (SEMAR) algorithm during perfusion examination in patients who had undergone reconstruction with neurosurgical clipping or endovascular coiling for treatment of aneurysms. METHODS: A total of 55 patients with implanted intracranial clips or coils (24 men and 31 women; mean age 60.15 ± 15.86 years) underwent perfusion studies evaluated by CT and CT angiography with a 320-row CT scanner...
November 16, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29133539/validation-of-the-ottawa-subarachnoid-hemorrhage-rule-in-patients-with-acute-headache
#8
Jeffrey J Perry, Marco L A Sivilotti, Jane Sutherland, Corinne M Hohl, Marcel Émond, Lisa A Calder, Christian Vaillancourt, Venkatesh Thirganasambandamoorthy, Howard Lesiuk, George A Wells, Ian G Stiell
BACKGROUND: We previously derived the Ottawa Subarachnoid Hemorrhage Rule to identify subarachnoid hemorrhage (SAH) in patients with acute headache. Our objective was to validate the rule in a new cohort of consecutive patients who visited an emergency department. METHODS: We conducted a multicentre prospective cohort study at 6 university-affiliated tertiary-care hospital emergency departments in Canada from January 2010 to January 2014. We included alert, neurologically intact adult patients with a headache peaking within 1 hour of onset...
November 13, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29131276/the-expression-of-mmp-7-in-serum-and-aneurysm-tissues-of-patients-with-abdominal-aortic-aneurysm-associated-with-hypertension-and-the-clinical-efficacy-of-endovascular-exclusion
#9
W-H Zhang, C-H Qiao, X Zhang, H Luo, X-K Sun
OBJECTIVE: To investigate the expression of matrix metalloproteinase-7 (MMP-7) in abdominal aortic aneurysm (AAA) with hypertension, and the clinical efficacy of endovascular exclusion. PATIENTS AND METHODS: Seventy-two cases of AAA with hypertension were retrospectively analyzed. Patients were divided into the observation group (34 cases) and control group (38 cases). The control group was treated by AAA incision with artificial vascular replacement, while the observation group was treated by endovascular graft exclusion...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29127197/communicating-malapposition-of-flow-diverters-assessed-with-optical-coherence-tomography-correlates-with-delayed-aneurysm-occlusion
#10
Robert M King, Olivia W Brooks, Erin T Langan, Jildaz Caroff, Frédéric Clarençon, Takamitsu Tamura, John Michael Wainwright, Matthew J Gounis, Miklós Marosfői, Ajit S Puri
BACKGROUND: Optical coherence tomography (OCT) is a high resolution intravascular imaging method that allows visualization of flow diverter struts and the vessel wall. In this study, malapposition of the flow diverter that continues into the neck of the aneurysm, named communicating malapposition (CM), was investigated as a potential factor for delayed aneurysm healing. METHODS: 40 New Zealand White rabbits underwent elastase induced aneurysm creation, and were subsequently assigned to one of four treatment groups based on flow diverter type and administration of antiplatelet therapy...
November 10, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29123158/inhibition-of-phosphatidylinositol-3-kinease-suppresses-formation-and-progression-of-experimental-abdominal-aortic-aneurysms
#11
Jing Yu, Rui Liu, Jianhua Huang, Lixin Wang, Wei Wang
Accumulating evidence suggests an important role of Phosphatidylinositol 3-kinease (PI3K) pathway in inflammatory cells infiltration. Given  the essential role of inflammatory cells infiltration during the formation and progression of abdominal aortic aneurysm (AAA), to investigate the possibility of preventing AAA formation and progression via targeting PI3K is anticipated. Here, experimental AAAs was created in rats by transient intraluminal porcine pancreatic elastase (PPE) infusion into the infrarenal aorta firstly...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29121822/investigation-of-efficacy-of-treatment-in-spinal-cord-injury-erythropoietin-versus-methylprednisolone
#12
Okan Ozkunt, Kerim Sariyilmaz, Halil Can Gemalmaz, Seren Gülsen Gürgen, Ulaş Yener, Fatih Dikici
BACKGROUND: Investigation of the expression of platelet-derived growth factor (PDGF)-β and glial fibrillary acidic protein (GFAP) in rats with spinal cord injury as a marker of neurologic recovery between groups treated with erythropoietin (EPO) and methylprednisolone (MP). METHODS: Thirty adult female rats were randomly divided into three even groups. A laminectomy was applied to thoracic ninth vertebra and contusion injury was induced by extradural application of an aneurysm clip...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29117032/a-preliminary-observational-study-of-anovulatory-uterine-bleeding-after-aneurysmal-subarachnoid-hemorrhage
#13
Suzanne M Brown, Susan W Fifield, Michael A Pizzi, David Alejos, Alexa N Richie, Tri A Dinh, William P Cheshire, Shon E Meek, William D Freeman
INTRODUCTION: It was observed that women with aneurysmal subarachnoid hemorrhage (aSAH) tended to have earlier menses than a typical 21- to 28-day cycle. The goal was to determine whether there is an association between aSAH and early onset of menses. METHODS: All cases of aSAH in women aged 18 to 55 years who were admitted to our facility's neuroscience intensive care unit from June 1, 2011, to June 30, 2012, were reviewed. The electronic healthcare record for each of these patients was examined for documentation of menses onset, computed tomography of the head, brain aneurysm characteristics, modified Fisher score and Glasgow Coma Scale on admission, presence/absence of vasospasm, medical/surgical history, and use of medications that affect the menstrual cycle...
December 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29116691/hyperbaric-oxygen-in-patients-with-ischemic-stroke-following-cardiac-surgery-a-retrospective-observational-trial
#14
Viktoria Heide-Marie Weixler, Ameli Elisabeth Yates, Markus Puchinger, Birgit Zirngast, Prisca Pondorfer, Beatrice Ratzenhofer-Komenda, Andrea Amegah-Sakotnik, Freyja-Maria Smolle-Juettner, Otto Dapunt
BACKGROUND: Hyperbaric oxygenation (HBO₂) involves breathing 100% oxygen under elevated ambient pressure in a hyperbaric chamber, thereby dissolving oxygen in the plasma. This results in an increase of arterial partial pressure of oxygen (pO₂). Though well established in experimental studies, HBO₂ treatment for ischemic stroke is still under discussion. METHODS: From 2002-2014 HBO₂ (2.2 bar, 90 minutes one/day; average number per patient: 4.7) was applied in 49 consecutive patients (32 males, 17 females, mean age: 68...
2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29115560/identification-of-key-genes-transcription-factors-and-micrornas-involved-in-intracranial-aneurysm
#15
Liang Wei, Qi Wang, Yanfei Zhang, Cheng Yang, Hongxin Guan, Yiming Chen, Zhiyang Sun
Intracranial aneurysm (IA) is a devastating disease, the pathogenesis of which remains to be elucidated. The present study aimed to determine the molecular mechanism of IA and to identify potential therapeutic targets using bioinformatics analysis. The GSE54083 dataset, which includes data from patients with ruptured IA and superficial temporal artery controls, was downloaded from the Gene Expression Omnibus, and differentially expressed genes (DEGs) were identified in the ruptured IA samples using the limma package in R...
November 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29100908/quality-of-life-in-children-participating-in-a-non-selective-inr-self-monitoring-vka-education-programme
#16
Pascal Amedro, Fanny Bajolle, Helena Bertet, Radhia Cheurfi, Dominique Lasne, Erika Nogue, Pascal Auquier, Marie-Christine Picot, Damien Bonnet
BACKGROUND: The quality of life (QoL) of children receiving vitamin K antagonist (VKA) treatment has been scarcely studied. AIM: To assess QoL of children, and its evolution, throughout our non-selective international normalized ratio (INR) self-monitoring education programme. METHODS: Children and parents completed QoL questionnaires (Qualin, PedsQL) during education sessions. Scores were compared with those from controls. RESULTS: A total of 111 children (mean±standard deviation age 8...
October 31, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29099301/analysis-of-overlapping-surgery-in-patients-undergoing-microsurgical-aneurysm-clipping-acute-and-long-term-outcomes-from-the-barrow-ruptured-aneurysm-trial
#17
Michael A Mooney, Scott Brigeman, Michael A Bohl, Elias D Simon, John P Sheehy, Steve W Chang, Robert F Spetzler
OBJECTIVE Overlapping surgery is a controversial subject in medicine today; however, few studies have examined the outcomes of this practice. The authors analyzed outcomes of patients with acutely ruptured saccular aneurysms who were treated with microsurgical clipping in a prospectively collected database from the Barrow Ruptured Aneurysm Trial. Acute and long-term outcomes for overlapping versus nonoverlapping cases were compared. METHODS During the study period, 241 patients with ruptured saccular aneurysms underwent microsurgical clipping...
November 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29095322/the-impact-of-the-endovascular-treatment-of-cerebral-aneurysms-on-headaches
#18
Mitra Assadi, Mandy Binning, Kenneth Liebman, Erol Veznedaroglu
OBJECTIVE: The co-occurrence of headaches and cerebral aneurysms is common in clinical practice, although a clear causal relationship has not been ascertained. We aimed to investigate the impact of endovascular obliteration of aneurysms on headaches using a cross-sectional, prospective, open-label protocol. We also sought to characterize the preexisting headaches in patients harboring cerebral aneurysms using the International Classification of Headache Disorders criteria. METHODS: A total of 33 patients were recruited into the study and underwent endovascular treatment for obliteration of their aneurysms...
November 2017: Neurologist
https://www.readbyqxmd.com/read/29088953/somatosensory-evoked-potentials-in-patients-with-high-grade-aneurysmal-subarachnoid-hemorrhage
#19
Klaus Christian Mende, Mathias Gelderblom, Cindy Schwarz, Patrick Czorlich, Nils Ole Schmidt, Eik Vettorazzi, Jan Regelsberger, Manfred Westphal, Tammam Abboud
OBJECTIVE The aim of this prospective study was to investigate the value of somatosensory evoked potentials (SEPs) in predicting outcome in patients with high-grade aneurysmal subarachnoid hemorrhage (SAH). METHODS Between January 2013 and January 2015, 48 patients with high-grade SAH (Hunt and Hess Grade III, IV, or V) who were admitted within 3 days after hemorrhage were enrolled in the study. Right and left median and tibial nerve SEPs were recorded on Day 3 after hemorrhage and recorded again 2 weeks later...
November 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/29081382/association-between-dexmedetomidine-use-and-neurological-outcomes-in-aneurysmal-subarachnoid-hemorrhage-patients-a-retrospective-observational-study
#20
Tomoya Okazaki, Toru Hifumi, Kenya Kawakita, Hajime Shishido, Daisuke Ogawa, Masanobu Okauchi, Atsushi Shindo, Masahiko Kawanishi, Keisuke Miyake, Takashi Tamiya, Yasuhiro Kuroda
PURPOSE: Recent studies in animal subarachnoid hemorrhage (SAH) models have reported that dexmedetomidine (DEX) use demonstrates significantly better neurological outcomes. This study aimed to evaluate whether DEX use is associated with favorable neurological outcomes (FO) in SAH patients. MATERIALS AND METHODS: We retrospectively reviewed all SAH patients between 2009 and 2017. We calculated the total dosage of DEX administered for the first 24h after admission...
October 24, 2017: Journal of Critical Care
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