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https://www.readbyqxmd.com/read/28438894/flow-diverter-treatment-of-intracranial-vertebral-artery-dissecting-pseudoaneurysms
#1
REVIEW
Russell Cerejo, Mark Bain, Nina Moore, Julian Hardman, Andrew Bauer, M Shazam Hussain, Thomas Masaryk, Peter Rasmussen, Gabor Toth
INTRODUCTION: Intracranial vertebral dissecting pseudoaneurysms are a rare, but increasingly recognized, cause of subarachnoid hemorrhage and ischemic stroke. The risks of aneurysm re-rupture and associated morbidity are high. The use of flow diverter stents for the treatment of these aneurysms has not been well studied. OBJECTIVE: To report our data and provide a summarized review of literature using flow diverter stents for the treatment of intracranial vertebral artery dissecting pseudoaneurysms...
April 24, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28433338/morbidity-of-endovascular-abdominal-aortic-aneurysm-repair-is-directly-related-to-diameter
#2
Douglas M Overbey, Natalia O Glebova, Brandon C Chapman, Patrick W Hosokawa, John C Eun, Mark R Nehler
OBJECTIVE: Previous randomized controlled trials have defined specific size thresholds to guide surgical decision-making in patients presenting with an abdominal aortic aneurysm (AAA). With recent advances in endovascular techniques, the anatomic considerations of AAA repair are rapidly changing. Our specific aims were to evaluate the most recent national population data to compare anatomic differences and perioperative outcomes in patients with AAA. METHODS: The American College of Surgeons National Surgical Quality Improvement Program was queried from 2011 to 2015 using the targeted vascular public use file...
April 19, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28427486/serum-gamma-glutamyl-transferase-levels-predict-functional-outcomes-after-aneurysmal-subarachnoid-hemorrhage
#3
Tian Xu, Wei Wang, Lin Zhai, Yun Feng Zhang, Hong Zhi Zhou, Xin Min Wu, Ai Hong Li, Li Li Xie, Xiao Jin Ning, Yu Teng Ji, Hong Mei Wang, Kai Fu Ke
OBJECTIVE: We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population. METHODS: A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ⋝ 3...
March 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28419337/targeted-embolization-of-aneurysms-associated-with-brain-arteriovenous-malformations-at-high-risk-for-surgical-resection-a-case-control-study
#4
Matthew D Alexander, Daniel S Hippe, Daniel L Cooke, Danial K Hallam, Steven W Hetts, Helen Kim, Michael T Lawton, Laligam N Sekhar, Louis J Kim, Basavaraj V Ghodke
BACKGROUND: High-risk components of brain arteriovenous malformations (BAVMs) can be targeted to reduce the risk of lesion rupture. OBJECTIVE: To evaluate targeted embolization of aneurysms against other means of treatment with a case-control analysis; we previously investigated this approach associated with BAVMs. METHODS: Retrospective analysis of patients with BAVMs was performed, identifying patients treated with intention to occlude only an aneurysm associated with a BAVM...
April 13, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28419304/incorporating-a-modified-graeb-score-to-the-modified-fisher-scale-for-improved-risk-prediction-of-delayed-cerebral-ischemia-following-aneurysmal-subarachnoid-hemorrhage
#5
Matt E Eagles, Blessing N R Jaja, R Loch Macdonald
BACKGROUND: Delayed cerebral ischemia (DCI) is a cause of poor outcome after aneurysmal subarachnoid hemorrhage. Risk scales to predict DCI have scarcely been evaluated for predictive accuracy. Accounting for volume of intraventricular hemorrhage (IVH) in the modified Fischer scale (mFS) may improve its predictive accuracy. OBJECTIVE: To compare the modified Graeb score (mGS) to the mFS for risk prediction of DCI, and to investigate whether incorporating an mGS cut-point into the mFS could improve predictive accuracy...
April 17, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28416930/what-are-the-prevalence-of-abdominal-aortic-aneurysm-in-patients-with-chronic-obstructive-pulmonary-diseases-and-the-characteristics-of-these-patients
#6
Ulku Aka Akturk, Nagihan Durmus Kocak, Suleyman Akturk, Mert Dumantepe, Aysun Sengul, Mehmet Arif Akcay, Makbule Ozlem Akbay, Feyyaz Kabadayi, Dilek Ernam
OBJECTIVE: To determine the prevalence of abdominal aortic aneurysm (AAA) in patients with chronic obstructive pulmonary disease (COPD) and to assess the characteristics of these patients. MATERIALS AND METHODS: Stable COPD patients (age, >40 years) were included in the study between January 2014 and June 2014. Patients with acute exacerbations and a previous lung resection were excluded. Data regarding demographic characteristics were recorded. The modified Medical Research Council (mMRC) dyspnea scale was used to assess the severity of breathlessness...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28413555/dissecting-intracranial-aneurysm-in-pregnancy-a-rare-association
#7
Manasi Mehrotra, Anant Mehrotra, Anup Nair, Arun Srivastava, Rabi Narayan Sahu, Mandakini Pradhan, Raj Kumar
We report a case of dissecting aneurysm of the right posterior cerebral artery presenting with sudden onset headache and altered behavior during labor. A 26-year-old P1001 with uncomplicated antenatal period, except history of headache off and on since 32 weeks of pregnancy, developed sudden onset headache and altered behavior during 3(rd) stage of labor. She had vaginal delivery and a live born male baby was delivered with good Apgar score. The CT was suggestive of subarachnoid hemorrhage and DSA was suggestive of dissecting aneurysm of the right P2 segment with hypoplasia of right P1 segment and A1 segment of posterior and anterior cerebral artery, respectively...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28413549/challenges-in-a-case-of-ophthalmic-artery-aneurysm-associated-with-abnormal-internal-carotid-arteries
#8
Eduard B Dinca, Felix Brehar, Andrei Giovani, Alexandru V Ciurea
Ophthalmic artery aneurysms account for 5% of all cerebral aneurysms and are an important cause of morbidity and mortality related to subarachnoid hemorrhage. The diagnosis is often made only when the aneurysm is large enough to become symptomatic. They remain technically challenging for both neurosurgeon and interventional radiologist. We present the case of a 62-year-old woman admitted for transient loss of consciousness, followed by generalized tonic-clonic seizures. Computed tomography (CT) showed a subarachnoid hemorrhage (SAH), clinically graded as Hunt and Hess III...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28412503/internet-search-volumes-in-brain-aneurysms-and-subarachnoid-hemorrhage-is-there-evidence-of-seasonality
#9
Jerry C Ku, Naif M Alotaibi, Justin Wang, George M Ibrahim, Tom A Schweizer, R Loch Macdonald
OBJECTIVE: Results of previous studies examining seasonal variation in the incidence of aneurysmal subarachnoid hemorrhage (SAH) are conflicting. The aim of this brief report is to investigate whether there is a seasonal effect in online search queries for SAH that may reflect an association between meteorological factors and aneurysm rupture. PATIENTS AND METHODS: We used the Google Trends data service to analyze the volume of internet queries for SAH on Google's search engine from January 1, 2004 to November 2016...
April 6, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28408632/4d-dsa-for-dynamic-visualization-of-cerebral-vasculature-a-single-center-experience-in-26-cases
#10
S Lang, P Gölitz, T Struffert, J Rösch, K Rössler, M Kowarschik, C Strother, A Doerfler
BACKGROUND AND PURPOSE: 4D DSA allows acquisition of time-resolved 3D reconstructions of cerebral vessels by using C-arm conebeam CT systems. The aim of our study was to evaluate this new method by qualitative and quantitative means. MATERIALS AND METHODS: 2D and 4D DSA datasets were acquired in patients presenting with AVMs, dural arteriovenous fistulas, and cerebral aneurysms. 4D DSA was compared with 2D DSA in a consensus reading of qualitative and quantitative parameters of AVMs (eg, location, feeder, associated aneurysms, nidus size, drainage, Martin-Spetzler Score), dural arteriovenous fistulas (eg, fistulous point, main feeder, diameter of the main feeder, drainage), and cerebral aneurysms (location, neck configuration, aneurysmal size)...
April 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28408258/predictors-of-postoperative-cerebral-ischemia-in-patients-with-ruptured-anterior-communicating-artery-aneurysms
#11
Pei-Sen Yao, Guo-Rong Chen, Shu-Fa Zheng, De-Zhi Kang
OBJECTIVE: Cerebral ischeamia is a major contributor to poor outcome after ruptured anterior communicating artery aneurysms (AcoAs), and is not well classified. Here we develop a classification and identify risk factors of cerebral ischemia after ruptured ACoAs. MATHERIAL AND METHODS: A total of 360 patients with ruptured ACoAs undergoing microsurgical clipping were collected. Sex, age, smoking, Hunt-Hess grade, Fisher grade, hospital stay, surgical timing, hypertension, diabetes, postoperative cerebral ischemia, and postoperative mRS score were collected...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28408198/plasma-8-iso-prostaglandin-f2%C3%AE-a-possible-prognostic-marker-in-aneurysmal-subarachnoid-hemorrhage
#12
De-Sheng Pan, Min Yan, Muhammad Hassan, Ze-Bin Fang, Man-Tao Chen
BACKGROUND: 8-iso-Prostaglandin F2α (8-iso-PGF2α) is a potential biomarker of oxidative stress. This study clarified whether plasma 8-iso-PGF2α concentrations were affected and its underlying relevance to prognosis in aneurysmal subarachnoid hemorrhage (aSAH). METHODS: In this prospective, observational study, a total of 170 controls and 170 aSAH patients were enrolled. Plasma 8-iso-PGF2α concentrations were detected using an ELISA. Severity was assessed by World Federation of Neurological Surgeons (WFNS) scale and modified Fisher grading scale...
April 11, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28402517/posterior-inferior-cerebellar-artery-vertebral-artery-subarachnoid-hemorrhage-a-comparison-of-saccular-vs-dissecting-aneurysms
#13
Mitchell T Foster, Amit Herwadkar, Hiren C Patel
BACKGROUND: Two distinct categories of aneurysms are described in relation to the posterior inferior cerebellar artery (PICA) and vertebral artery (VA): saccular (SA) and dissecting (DA) types. This distinction is often unrecognized because abnormalities here are uncommon and most studies are small. OBJECTIVE: To determine if there are any differences in the clinical presentation, in-hospital course, or outcomes in patients with DA vs SA of the PICA or VA. METHODS: Thirty-eight patients with a VA or PICA aneurysm were identified from a departmental subarachnoid hemorrhage database and categorized into DA or SA types...
April 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28390921/long-term-comparison-of-endovascular-and-open-repair-of-abdominal-aortic-aneurysms-retrospective-analysis-of-matched-cohorts-with-propensity-score
#14
Masayuki Sugimoto, Akio Koyama, Kiyoaki Niimi, Akio Kodama, Hiroshi Banno, Kimihiro Komori
BACKGROUND: Although recent guidelines recommend EVAR for robust younger patients, we have been limiting our indication to older patients or those who are physically frail. This study compares long-term outcomes of our series of abdominal aortic aneurysms (AAA) treated with endovascular repair (ER) and open surgery (OS), using propensity-score matching. METHODS: Between June 2007 and October 2014, 819 patients with infrarenal AAA underwent elective repair at our institution...
April 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28387624/dolichoectatic-aneurysms-of-the-vertebrobasilar-system-clinical-and-radiographic-factors-that-predict-poor-outcomes
#15
David S Xu, Michael R Levitt, M Yashar S Kalani, Leonardo Rangel-Castilla, Celene B Mulholland, Isaac J Abecassis, Ryan P Morton, John D Nerva, Adnan H Siddiqui, Elad I Levy, Robert F Spetzler, Felipe C Albuquerque, Cameron G McDougall
OBJECTIVE Fusiform dolichoectatic vertebrobasilar aneurysms are rare, challenging lesions. The natural history of these lesions and medium- and long-term patient outcomes are poorly understood. The authors sought to evaluate patient prognosis after diagnosis of fusiform dolichoectatic vertebrobasilar aneurysms and to identify clinical and radiographic predictors of neurological deterioration. METHODS The authors reviewed multiple, prospectively maintained, single-provider databases at 3 large-volume cerebrovascular centers to obtain data on patients with unruptured, fusiform, basilar artery dolichoectatic aneurysms diagnosed between January 1, 2000, and January 1, 2015...
April 7, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28387623/flow-diverter-devices-in-ruptured-intracranial-aneurysms-a-single-center-experience
#16
Emilio Lozupone, Mariangela Piano, Luca Valvassori, Luca Quilici, Guglielmo Pero, Emiliano Visconti, Edoardo Boccardi
OBJECTIVE In this single-center series, the authors retrospectively evaluated the effectiveness, safety, and midterm follow-up results of ruptured aneurysms treated by implantation of a flow diverter device (FDD). METHODS The records of 17 patients (12 females, 5 males, average World Federation of Neurosurgical Societies score = 2.9) who presented with subarachnoid hemorrhage (SAH) due to the rupture of an intracranial aneurysm treated with an FDD were retrospectively reviewed. Of 17 ruptured aneurysms, 8 were blood blister-like aneurysms and the remaining 9 were dissecting aneurysms...
April 7, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28386837/effect-of-delayed-onset-prostacyclin-on-markers-of-endothelial-function-and-damage-after-subarachnoid-hemorrhage
#17
Mikkel Gybel-Brask, Rune Rasmussen, Jakob Stensballe, Pär I Johansson, Sisse R Ostrowski
BACKGROUND: Subarachnoid hemorrhage (SAH) is a neurological emergency. Delayed ischemic neurological deficit is one of the main causes of poor outcome after SAH and is probably caused, at least in part, by cerebral vasospasm. The pathophysiology of this is multifaceted, but endothelial damage and activation as well as glycocalyx damage have been implicated. Prostacyclin has been shown to protect damaged and activated endothelium and to facilitate glycocalyx repair. We investigated biomarkers of endothelial activation and damage in patients with SAH randomized to 5 days prostacyclin infusion or placebo...
April 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28386685/a-machine-learning-approach-to-investigate-the-relationship-between-shape-features-and-numerically-predicted-risk-of-ascending-aortic-aneurysm
#18
Liang Liang, Minliang Liu, Caitlin Martin, John A Elefteriades, Wei Sun
Geometric features of the aorta are linked to patient risk of rupture in the clinical decision to electively repair an ascending aortic aneurysm (AsAA). Previous approaches have focused on relationship between intuitive geometric features (e.g., diameter and curvature) and wall stress. This work investigates the feasibility of a machine learning approach to establish the linkages between shape features and FEA-predicted AsAA rupture risk, and it may serve as a faster surrogate for FEA associated with long simulation time and numerical convergence issues...
April 6, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28383672/cerebral-revascularization-for-aneurysms-in-the-flow-diverter-era
#19
David C Straus, Harley Brito da Silva, Lynn McGrath, Michael R Levitt, Louis J Kim, Basavaraj V Ghodke, Jason K Barber, Laligam N Sekhar
BACKGROUND: Cerebral bypass has been an important tool in the treatment of complex intracranial aneurysms. The recent advent of flow-diverting stents (FDS) has expanded the capacity for endovascular arterial reconstruction. OBJECTIVE: We investigated how the advent of FDS has impacted the application and outcomes of cerebral bypass in the treatment of intracranial aneurysms. METHODS: We reviewed a consecutive series of cerebral bypasses during aneurysm surgery over the course of 10 years...
April 5, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28382536/follow-up-assessment-of-coiled-intracranial-aneurysms-using-zte-mra-as-compared-with-tof-mra-a-preliminary-image-quality-study
#20
Song'an Shang, Jing Ye, Xianfu Luo, Jianxun Qu, Yong Zhen, Jingtao Wu
OBJECTIVES: To prospectively assess coiled intracranial aneurysms using a novel non-contrast enhanced zero echo time (zTE) MR angiography (MRA) method, and compare its image quality with time-of-flight (TOF) MRA, using digital subtraction angiography (DSA) as reference. METHODS: Twenty-five patients (10 males and 15 females; age 53.96 ± 12.46 years) were enrolled in this monocentric study. MRA sequences were performed 24 h before DSA. Susceptibility artefact intensity and flow signal within the parent artery were carried out using a 4-point scale...
April 5, 2017: European Radiology
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