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https://www.readbyqxmd.com/read/28511502/comparative-evaluation-of-three-herbal-solutions-on-the-disinfection-of-guttapercha-cones-an-in-vitro-study
#1
Pratap Kumar Mukka, Samba Shiva Rao Pola, Nanda Kumar Kommineni, Mayuri Sailaja Pachalla, Anand Ramtheerth Karne, Karthik Labishetty, Supriya Kommineni, Praveen Chilakabathini
INTRODUCTION: Guttapercha (GP) cones are usually supplied in aseptic, sealed packages from the manufacturers, but once exposed to the dental office environment or even by handling; they can be contaminated by a number of microorganisms. Supplementary decontamination of GP cones is critical. As they cannot be sterilized by moist or dry heat, cold sterilization, using disinfectants should be used. AIM: The aim of the study was to evaluate rapid, reliable, convenient and effective method of disinfection of GP cones using readily available herbal solutions such as Aloevera Juice, Amla Juice and Pancha Tulsi...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28507956/an-unusual-case-of-giant-cell-tumor-of-first-metatarsal-a-rare-case-report-and-review-of-literature
#2
Kumar Prashant, Tulsi Das Bhattacharyya, Herman Frank, Prema Ram
INTRODUCTION: Giant cell tumor (GCT) or osteoclastoma is an osteolytic, mostly benign but locally aggressive tumor occurring in young adults at the epiphysis. Area of predilection is mainly long bones (85-90%). 4% of GCT are also found in iliac bone, spine and only 2% in hand (of which GCT phalanges are more common than metacarpal). GCT of metatarsal is a very rare occurrence with very few cases being reported so far. We report a case of GCT 1(st) metatarsal in a 40-year-old male which is a very rare entity...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28422646/coordinated-control-of-terminal-differentiation-and-restriction-of-cellular-plasticity
#3
Tulsi Patel, Oliver Hobert
The acquisition of a specific cellular identity is usually paralleled by a restriction of cellular plasticity. Whether and how these two processes are coordinated is poorly understood. Transcription factors called terminal selectors activate identity-specific effector genes during neuronal differentiation to define the structural and functional properties of a neuron. To study restriction of plasticity, we ectopically expressed C. elegans CHE-1, a terminal selector of ASE sensory neuron identity. In undifferentiated cells, ectopic expression of CHE-1 results in activation of ASE neuron type-specific effector genes...
April 19, 2017: ELife
https://www.readbyqxmd.com/read/28400848/the-clinical-efficacy-and-safety-of-tulsi-in-humans-a-systematic-review-of-the-literature
#4
REVIEW
Negar Jamshidi, Marc M Cohen
Tulsi, also known as holy basil, is indigenous to the Indian continent and highly revered for its medicinal uses within the Ayurvedic and Siddha medical systems. Many in vitro, animal and human studies attest to tulsi having multiple therapeutic actions including adaptogenic, antimicrobial, anti-inflammatory, cardioprotective, and immunomodulatory effects, yet to date there are no systematic reviews of human research on tulsi's clinical efficacy and safety. We conducted a comprehensive literature review of human studies that reported on a clinical outcome after ingestion of tulsi...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28377654/a-comparative-study-of-ion-diffusion-from-calcium-hydroxide-with-various-herbal-pastes-through-dentin
#5
Priyanka Dausage, Rajesh B Dhirawani, Jayant Marya, Vrinda Dhirawani, Vijayendra Kumar
AIM: The aim of this study was to evaluate the diffusion ability of ions through dentinal tubules of different nonalcoholic calcium hydroxide-containing herbal pastes and compare it with the calcium hydroxide paste prepared with saline. MATERIALS AND METHODS: A total of 36 single-rooted premolar teeth were used in this study. The tooth crowns were removed and the root canals were prepared. Depending on the vehicle to be used for preparing calcium hydroxide pastes, six groups were made: Group I: Ca(OH)2 saline paste (control group), group II: Ca(OH)2 papaya latex paste, group III: Ca(OH)2 coconut water paste, group IV: Ca(OH)2 Ashwagandha (Withania somnifera) paste, group V: Ca(OH)2 Tulsi (Ocimum tenuiflorum) paste, and group VI: Ca(OH)2 garlic (Allium sativum) paste...
January 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28359741/targeting-the-mercapturic-acid-pathway-and-vicenin-2-for-prevention-of-prostate-cancer
#6
REVIEW
Sharad S Singhal, Divya Jain, Preeti Singhal, Sanjay Awasthi, Jyotsana Singhal, David Horne
Prostate cancer (CaP) is often androgen-sensitive malignancy and regresses upon inhibition of androgen signaling. However, CaP, nearly always develops androgen resistance and progresses to aggressive and lethal androgen-independent CaP, which lacks satisfactory therapy. For metastatic CaP, patients are often treated with Taxotere (docetaxel), a cytoskeleton-targeted chemotherapy drug, that provides transient palliative benefit but to which patients rapidly develop drug-resistance. Combination chemotherapy may be used instead, but is more toxic and adds little clinically relevant benefit over docetaxel...
March 28, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28294638/potential-targetability-of-multi-walled-carbon-nanotube-loaded-with-silver-nanoparticles-photosynthesized-from-ocimum-tenuiflorum-tulsi-extract-in-fertility-diagnosis
#7
Pradeep K Jha, Rakhi K Jha, Dilip Rout, Sathishkumar Gnanasekar, Suresh Vs Rana, Maidul Hossain
Nanocarrier mediated targeted delivery and biosensing in reproductive health care is a major exploratory domain. This work demonstrates the loading of silver nanoparticle (AgNP) inside the multiwalled Carbon nanotube(MWCNT) and their targetability to the intracellular part of the sperm cell for its further application in biosensing based infertility diagnosis. Ocimum tenuiflorum (tulsi extract) mediated photosynthesized AgNP exhibited spherical shape, 5-40nm size and surface plasmonic resonance at 430 nm...
March 15, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28256465/comparison-of-haemoglobin-estimates-using-direct-indirect-cyanmethaemoglobin-methods
#8
Priyanka Gupta Bansal, Gurudayal Singh Toteja, Neena Bhatia, Sanjeev Gupta, Manpreet Kaur, Tulsi Adhikari, Ashok Kumar Garg
BACKGROUND & OBJECTIVES: Estimation of haemoglobin is the most widely used method to assess anaemia. Although direct cyanmethaemoglobin method is the recommended method for estimation of haemoglobin, but it may not be feasible under field conditions. Hence, the present study was undertaken to compare indirect cyanmethaemoglobin method against the conventional direct method for haemoglobin estimation. METHODS: Haemoglobin levels were estimated for 888 adolescent girls aged 11-18 yr residing in an urban slum in Delhi by both direct and indirect cyanmethaemoglobin methods, and the results were compared...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28024715/incidence-of-postoperative-nausea-and-vomiting-following-gynecological-laparoscopy-a-comparison-of-standard-anesthetic-technique-and-propofol-infusion
#9
Pradipta Bhakta, Bablu Rani Ghosh, Umesh Singh, Preeti S Govind, Abhinav Gupta, Kulwant Singh Kapoor, Rajesh Kumar Jain, Tulsi Nag, Dipanwita Mitra, Manjushree Ray, Vikash Singh, Gauri Mukherjee
OBJECTIVE: To determine the safety, efficacy, and feasibility of propofol-based anesthesia in gynecological laparoscopies in reducing incidences of postoperative nausea and vomiting compared to a standard anesthesia using thiopentone/isoflurane. DESIGN: Randomized single-blind (for anesthesia techniques used) and double-blind (for postoperative assessment) controlled trial. SETTING: Operation theater, postanesthesia recovery room, teaching hospital...
December 2016: Acta Anaesthesiologica Taiwanica: Official Journal of the Taiwan Society of Anesthesiologists
https://www.readbyqxmd.com/read/27924186/treatment-of-chronic-hepatitis-c-infection-with-sofosbuvir-based-regimens-in-a-commercially-insured-patient-population
#10
John Barron, Yiqiong Xie, Sze-Jung Wu, Jeff White, Joseph Singer, Bernard Tulsi, Alan Rosenberg
BACKGROUND: The response to treatment with direct-acting antiviral agents in patients with chronic hepatitis C virus (HCV) is not well-characterized in the real-world setting. OBJECTIVE: To describe patients' response to 3 sofosbuvir-based treatment regimens among commercially insured patients with chronic HCV. METHODS: In this observational study, we identified patients with HCV who started sofosbuvir treatment with 1 of 3 sofosbuvir-based regimens between December 1, 2013, and April 30, 2014, in the HealthCore Integrated Research Database, a large managed care repository...
September 2016: American Health & Drug Benefits
https://www.readbyqxmd.com/read/27834327/factors-associated-with-utilization-of-antenatal-care-services-among-tribal-women-a-study-of-selected-states
#11
Tulsi Adhikari, Damodar Sahu, Saritha Nair, Kalyan B Saha, Ravendra K Sharma, Arvind Pandey
BACKGROUND & OBJECTIVES: Despite various efforts by the Government of India, utilization of antenatal care (ANC) services continues to be low among women from rural areas particularly those belonging to the Scheduled Tribes. The present study was undertaken to examine the factors associated with the utilization of ANC services among women in four States including Rajasthan, Odisha, Chhattisgarh and Madhya Pradesh which constitute a good share of tribal population of the country. METHODS: Data from third round of District Level Household and Facility Survey, 2007-08 (DLHS-3) have been used...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27810183/obesity-may-be-the-common-pathway-for-sleep-disordered-breathing-in-women-with-polycystic-ovary-syndrome
#12
Jyotsna Suri, Jagdish Chander Suri, Bidisha Chatterjee, Pratima Mittal, Tulsi Adhikari
OBJECTIVE: Polycystic ovary syndrome (PCOS) is one of the most common endocrinological disorders in women of reproductive age, and is characterized by hyperandrogenism. It is associated with long-term metabolic dysfunctions including sleep-disordered breathing (SDB). We hypothesized that the increased prevalence of SDB in PCOS results from raised testosterone levels. METHODS: This was a prospective, cross-sectional, case-control study in which 50 case patients with untreated PCOS and 100 control subjects were included...
August 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27776828/mutation-analysis-of-sporadic-early-onset-alzheimer-s-disease-using-the-neurox-array
#13
Imelda S Barber, Anne Braae, Naomi Clement, Tulsi Patel, Tamar Guetta-Baranes, Keeley Brookes, Christopher Medway, Sally Chappell, Rita Guerreiro, Jose Bras, Dena Hernandez, Andrew Singleton, John Hardy, David M Mann, Kevin Morgan
We have screened sporadic early-onset Alzheimer's disease (sEOAD, n = 408) samples using the NeuroX array for known causative and predicted pathogenic variants in 16 genes linked to familial forms of neurodegeneration. We found 2 sEOAD individuals harboring a known causative variant in PARK2 known to cause early-onset Parkinson's disease; p.T240M (n = 1) and p.Q34fs delAG (n = 1). In addition, we identified 3 sEOAD individuals harboring a predicted pathogenic variant in MAPT (p.A469T), which has previously been associated with AD...
January 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/27729839/identification-of-suitable-natural-inhibitor-against-influenza-a-h1n1-neuraminidase-protein-by-molecular-docking
#14
Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for overcoming the epidemics. Traditionally, different plant extracts of garlic, ginger, kalmegh, ajwain, green tea, turmeric, menthe, tulsi, etc. have been used as hopeful source of prevention and treatment of human influenza. The H1N1 virus contains an important glycoprotein, known as neuraminidase (NA) that is mainly responsible for initiation of viral infection and is essential for the life cycle of H1N1...
September 2016: Genomics & Informatics
https://www.readbyqxmd.com/read/27504417/evaluation-of-effect-of-brushite-calcite-and-two-indigenous-herbs-in-removal-of-fluoride-from-water
#15
Manumanthu Venkata Ramesh, Puvvadi Gopalakrishna Naveenkumar, Gouder Manjunath Prashant, Basha Sakeenabi, Allamaprabhu, Kothyala Vijetha
INTRODUCTION: The acceptable concentration of fluoride in drinking water is 1.5mg/l. Excess fluoride in drinking water causes fluorosis. Fluorosis is an important public health problem in India. Several treatment technologies suggested in the past for removing excess fluoride generated and causes various chemical byproductswhich are hazardous to public. In recent years, there has been a resurgence of interest to use natural materials due to cost and associated health and environmental concerns of synthetic organic polymers and inorganic chemicals...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27504299/a-solid-pseudopapillary-tumour-of-the-head-of-pancreas-a-rare-case-report-diagnosed-by-fine-needle-aspiration-cytology
#16
Tulsi Shyam Chhadi, Archana Hemant Deshpande, Shyam Atmaram Chhadi, Dinkar T Kumbhalkar, Waman K Raut
Solid Pseudopapillary Tumour (SPPT) is a distinctive tumour of low malignant potential with a striking and unexplained predilection for adolescent girls and young women. Hence it is important to distinguish this rare tumour from other pancreatic tumours with similar cytomorphologic features because an accurate preoperative diagnosis is highly desirable since these patients can have long survival with adequate surgery. We report a case of the rare SPPT of the pancreas in a young girl who presented with nonspecific pain in the abdomen...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27396915/structure-activity-relationship-studies-on-holy-basil-ocimum-sanctum-l-based-flavonoid-orientin-and-its-analogue-for-cytotoxic-activity-in-liver-cancer-cell-line-hepg2
#17
Feroz Khan, Pooja Sharma, Om Prakash, Aparna Shukla, Prema G Vasudev, Suaib Luqman, Santosh Kumar Srivastava
O. sanctum L. (O. tenuiflorum) is an important sacred medicinal plant of India known as Holy Basil or Tulsi. The chemical composition of volatile oil is highly complex and comprises high ratio of phenylpropanoids and terpenes, and some phenolic compound or flavonoids such as orientin and vicenin. These minor flavonoids known to be antioxidant and anticancer in nature. Orientin reported as potential anticancer agent due to anti-proliferative activity on human liver cancer cell line HepG2, but its mechanism of action are not fully explored...
July 9, 2016: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/27365872/tricyclic-antidepressant-overdose-treated-with-adjunctive-lipid-rescue-and-plasmapheresis
#18
Chibuzo Clement Odigwe, Madiha Tariq, Tulsi Kotecha, Usman Mustafa, Nizar Senussi, Isaac Ikwu, Anirban Bhattarcharya, John Ifeanyi Ngene, Kizito Ojiako, Nkemakolam Iroegbu
Tricyclic antidepressant poisoning remains a major cause of morbidity and mortality, particularly in the setting of suicidal attempts. The current standard of care for treatment is the administration of sodium bicarbonate infusion. Adjunctive lipid emulsion therapy and plasmapheresis have received attention recently. We report an 18-year-old patient who was successfully managed with lipid emulsion and plasmapheresis as adjuncts to sodium bicarbonate treatment and review some of the recent literature.
July 2016: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/27312248/a-comparative-study-of-two-percutaneous-pinning-techniques-lateral-vs-medial-lateral-for-gartland-type-iii-pediatric-supracondylar-fracture-of-the-humerus
#19
RANDOMIZED CONTROLLED TRIAL
Kumar Prashant, Devendra Lakhotia, Tulsi Das Bhattacharyya, Anil Kumar Mahanta, Aakhil Ravoof
BACKGROUND: The management of displaced supracondylar fracture of the humerus with closed reduction and percutaneous pin fixation is the most widely accepted method of treatment, but controversy continues regarding the pin fixation techniques. A prospective randomized controlled study was undertaken to compare the stability, functional outcome and iatrogenic ulnar nerve injury between lateral pin fixation and medial-lateral pin fixation. MATERIAL AND METHOD: Sixty-two patients with Gartland type III supracondylar fracture of the humerus were randomized into two groups-lateral pin fixation (n = 31) and medial-lateral pin fixation (n = 31)...
September 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27242708/antimicrobial-activity-of-tulsi-ocimum-tenuiflorum-essential-oil-and-their-major-constituents-against-three-species-of-bacteria
#20
Hanaa A Yamani, Edwin C Pang, Nitin Mantri, Margaret A Deighton
In recent years scientists worldwide have realized that the effective life span of any antimicrobial agent is limited, due to increasing development of resistance by microorganisms. Consequently, numerous studies have been conducted to find new alternative sources of antimicrobial agents, especially from plants. The aims of this project were to examine the antimicrobial properties of essential oils distilled from Australian-grown Ocimum tenuiflorum (Tulsi), to quantify the volatile components present in flower spikes, leaves and the essential oil, and to investigate the compounds responsible for any activity...
2016: Frontiers in Microbiology
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