keyword
MENU ▼
Read by QxMD icon Read
search

Addiction; methadone

keyword
https://www.readbyqxmd.com/read/28074831/rgs9-2-modulates-responses-to-oxycodone-in-pain-free-and-chronic-pain-states
#1
Sevasti Gaspari, Valeria Cogliani, Lefteris Manouras, Ethan M Anderson, Vasiliki Mitsi, Kleopatra Avrampou, Fiona B Carr, Venetia Zachariou
Regulator of G protein signalling 9-2 (RGS9-2) is a striatal enriched signal transduction modulator, known to play a critical role in the development of addiction-related behaviours following exposure to psychostimulants or opioids. RGS9-2 controls the function of several GPCRs, including dopamine and mu opioid (MOR) receptors. We previously showed that RGS9-2 complexes negatively control morphine analgesia, and promote the development of morphine tolerance. In contrast, RGS9-2 positively modulates the actions of other opioid analgesics, such as fentanyl and methadone...
January 11, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28051842/the-use-of-auricular-acupuncture-in-opioid-use-disorder-a-systematic-literature-review
#2
REVIEW
Tanya E Baker, Grace Chang
BACKGROUND AND OBJECTIVES: Opioid use disorder (OUD) is a chronic disease with significant personal, societal, and public health consequences. Even for the minority who receive the most effective evidence-based treatments, morbidity, and mortality remain significant. These facts, along with the recovery movement calling for individualized, holistic, culturally sensitive care, have led to the exploration of adjunctive interventions including acupuncture. Despite hundreds of international trials, however, there is a lack of consensus regarding its efficacy in OUD due in large part to methodological issues of trials to date...
December 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/28050185/comparing-acceptance-and-commitment-group-therapy-and-12-steps-narcotics-anonymous-in-addict-s-rehabilitation-process-a-randomized-controlled-trial
#3
Manoochehr Azkhosh, Ali Farhoudianm, Hemn Saadati, Fateme Shoaee, Leila Lashani
Objective: Substance abuse is a socio-psychological disorder. The aim of this study was to compare the effectiveness of acceptance and commitment therapy with 12-steps Narcotics Anonymous on psychological well-being of opiate dependent individuals in addiction treatment centers in Shiraz, Iran. Method: This was a randomized controlled trial. Data were collected at entry into the study and at post-test and follow-up visits. The participants were selected from opiate addicted individuals who referred to addiction treatment centers in Shiraz...
October 2016: Iranian Journal of Psychiatry
https://www.readbyqxmd.com/read/28005315/methadone-callbacks-within-a-veterans-affairs-opioid-treatment-program-detecting-methadone-misuse
#4
Ann J Cotton, Leandra J Shipley, Lisa H Glynn, Josie Tracy, Andrew J Saxon
BACKGROUND AND OBJECTIVES: A "callback" requires patients to bring in take-home methadone doses for inspection. An opioid treatment program (OTP) quality-improvement project examined random versus "for-cause" callbacks. METHOD: Eighty-two random callbacks and 60 for-cause callbacks were conducted among patients enrolled in an OTP (N = 183). RESULTS: Among patients with more take home doses, 6% of random callbacks versus 44% of for-cause callbacks were failed...
January 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/27997065/depression-and-severity-of-substance-dependence-among-heroin-dependent-patients-with-adhd-symptoms
#5
Yin-To Liao, Chi-Yen Chen, Mei-Hing Ng, Kuo-You Huang, Wen-Chuan Shao, Tsang-Yaw Lin, Vincent Chin-Hung Chen, Michael Gossop
BACKGROUND AND OBJECTIVES: Comorbid attention deficit hyperactivity disorder (ADHD) symptoms are highly prevalent among heroin-dependent patients. We aim to investigate differences in dependence severity, depression, and quality of life between heroin-dependent patients with and without ADHD-screened positive. METHODS: Heroin-dependent participants (n = 447) entering methadone maintenance treatment were divided into ADHD-screened positive (ADHD-P) and ADHD-screened negative (ADHD-N) groups according to scores of Adult ADHD Self-Report Scale (ASRS)...
January 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/27974484/buprenorphine-norbuprenorphine-r-methadone-and-s-methadone-upregulate-bcrp-abcg2-expression-by-activating-aryl-hydrocarbon-receptor-in-human-placental-trophoblasts
#6
Naveen K Neradugomma, Michael Z Liao, Qingcheng Mao
Opioid dependence during pregnancy is a rising concern. Maintaining addicted pregnant women on long-acting opioid receptor agonist is the most common strategy to manage pregnancy drug abuse. Methadone (MET) and Buprenorphine (BUP) are widely prescribed for opiate-maintenance therapy. Norbuprenorphine (NBUP) is the primary active metabolite of BUP. These medications can cross the placenta to the fetus, leading to postpartum neonatal abstinence syndrome. Despite their use during pregnancy, little is known about the cellular changes brought about by these drugs in the placenta...
December 14, 2016: Molecular Pharmacology
https://www.readbyqxmd.com/read/27955689/the-effect-of-bundling-medication-assisted-treatment-for-opioid-addiction-with-mhealth-study-protocol-for-a-randomized-clinical-trial
#7
David H Gustafson, Gina Landucci, Fiona McTavish, Rachel Kornfield, Roberta A Johnson, Marie-Louise Mares, Ryan P Westergaard, Andrew Quanbeck, Esra Alagoz, Klaren Pe-Romashko, Chantelle Thomas, Dhavan Shah
BACKGROUND: Opioid dependence has devastating and increasingly widespread consequences and costs, and the most common outcome of treatment is early relapse. People who inject opioids are also at disproportionate risk for contracting the human immunodeficiency virus (HIV) and hepatitis C virus (HCV). This study tests an approach that has been shown to improve recovery rates: medication along with other supportive services (medication-assisted treatment, or MAT) against MAT combined with a smartphone innovation called A-CHESS (MAT + A-CHESS)...
December 12, 2016: Trials
https://www.readbyqxmd.com/read/27933094/the-newer-opioid-agonist-treatment-with-lower-substitutive-opiate-doses-is-associated-with-better-toxicology-outcome-than-the-older-harm-reduction-treatment
#8
Jacopo V Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca, Icro Maremmani
BACKGROUND: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold facilities for opioid addiction, focusing on pharmacological maintenance according to the Dole and Nyswander strategy. We aimed to compare the impact of HRT and OAT on patient outcome, as assessed through negativity for drugs on about 1-year urinalyses...
2016: Annals of General Psychiatry
https://www.readbyqxmd.com/read/27843967/prevalence-of-pulmonary-edema-among-the-deceased-cases-with-acute-methadone-poisoning-a-report-from-iran
#9
Nastaran Eizadi-Mood, Seyed Amir Hossein Madani Naeini, Mahrang Hedaiaty, Ali Mohammad Sabzghabaee, Maryam Moudi
OBJECTIVE: Methadone poisoning is common in our society, mainly in drug addicts. One of its lethal complications is pulmonary edema. Therefore, we evaluated the prevalence of pulmonary edema in the deceased cases with methadone poisoning and its possible relationship with some medical variables. METHODS: In this cross-sectional study which was done in 2014, we have investigated the deceased patients with methadone toxicity who underwent autopsy at Isfahan Forensic Medicine Department (Iran)...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27821595/cannabis-exposure-as-an-interactive-cardiovascular-risk-factor-and-accelerant-of-organismal-ageing-a-longitudinal-study
#10
Albert Stuart Reece, Amanda Norman, Gary Kenneth Hulse
OBJECTIVES: Many reports exist of the cardiovascular toxicity of smoked cannabis but none of arterial stiffness measures or vascular age (VA). In view of its diverse toxicology, the possibility that cannabis-exposed patients may be ageing more quickly requires investigation. DESIGN: Cross-sectional and longitudinal, observational. Prospective. SETTING: Single primary care addiction clinic in Brisbane, Australia. PARTICIPANTS: 11 cannabis-only smokers, 504 tobacco-only smokers, 114 tobacco and cannabis smokers and 534 non-smokers...
November 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27809831/tailoring-a-brief-intervention-for-illicit-drug-use-and-alcohol-use-in-irish-methadone-maintained-opiate-dependent-patients-a-qualitative-process
#11
Catherine Darker, Brion Sweeney, Eamon Keenan, Lucy Whiston, Rolande Anderson, Joe Barry
BACKGROUND: The World Health Organization (WHO) recommend the tailoring of a brief intervention (BI) programme of research to ensure that it is both culturally and contextually appropriate for the country and the environment in which it is being tested. The majority of BI research has been conducted with non-opioid dependent participants. The current study developed a tailored BI for illicit drug use and alcohol use to a methadone maintained opioid dependent polydrug using cohort of patients...
November 3, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27806462/retention-and-relapse-in-methadone-maintenance-treatment-a-descriptive-analytical-study
#12
Reza Mollajavadi, Narges Beyraghi, Isa Fathi, Robab Teymouri, Arya Hamedanchi
BACKGROUND: Despite the considerable efforts made in Iran to treat people with addiction, relapse is still common. This study was designed to determine retention and relapse rates and related factors at Yasin Methadone Maintenance Treatment Center. PATIENTS & METHODS: In this study, retention rate, relapse rate, and related factors were examined in 74 cases using a descriptive-analytical method. Information about 20 variables were gathered from patient medical records using an information form and a checklist and data was analyzed by the chi-square, Fisher's exact, and Mann-Whitney tests using SPSS software...
June 30, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27747887/multi-family-therapy-with-a-reflecting-team-a-preliminary-study-on-efficacy-among-opiate-addicts-in-methadone-maintenance-treatment
#13
Miguel Garrido-Fernández, Juan A Marcos-Sierra, Ana López-Jiménez, Iñigo Ochoa de Alda
In this study, we evaluate the efficacy of multi-family therapy at reducing the addiction severity and at improving the psychological and family dynamics of opiate addicts receiving methadone treatment at a public treatment center. The study compares multi-family therapy with a reflecting team (MFT-RT) and a standard treatment following a methadone maintenance treatment program. The results show that multi-family therapy with a reflecting team effectively reduces the addiction severity in several of the areas evaluated and noted that this effect is superior to standard treatment...
October 17, 2016: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/27730106/impact-of-a-methadone-maintenance-program-on-an-aboriginal-community-a-qualitative-study
#14
Michel Landry, Nadia Veilleux, Julie-Eve Arseneault, Saneea Abboud, André Barrieau, Mathieu Bélanger
BACKGROUND: Methadone maintenance treatment programs implemented in Aboriginal communities have proven to be beneficial for the control of opioid addiction and its associated consequences, but the perceptions and opinions of different community members about these programs remain elusive. The goal of this study was to determine the perceptions of members of a First Nation community in New Brunswick, Canada, on the implementation of a methadone maintenance treatment program and its effects on the community...
July 2016: CMAJ Open
https://www.readbyqxmd.com/read/27723910/neonatal-abstinence-syndrome-twelve-years-of-experience-at-a-regional-referral-center
#15
S Mücke, M Nagel, J P Siedentopf, C Bührer, D Hüseman
Background: Infants exposed to opiates antenatally display withdrawal symptoms after birth referred to as neonatal abstinence syndrome (NAS). Patients: A total of 366 newborns (166 females, 10 twins) from 361 mothers were diagnosed with NAS from 2000 to 2011 at a single large metropolitan referral center. Methods: Retrospective chart review of all newborn infants exposed to opiates in utero. Results: 20% were premature (gestational age<37 weeks), 32% were small-for-gestational-age (<10(th) percentile)...
October 10, 2016: Klinische Pädiatrie
https://www.readbyqxmd.com/read/27688642/cross-sectional-study-of-the-severity-of-self-reported-depressive-symptoms-in-heroin-users-who-participate-in-a-methadone-maintenance-treatment-program
#16
Yafei Wu, Shiyan Yan, Yanping Bao, Zhi Lian, Zhi Qu, Zhimin Liu
BACKGROUND: Methadone maintenance treatment (MMT) is widely recognized as an effective method of combatting narcotic addiction. MMT reduces heroin withdrawal symptoms and, thus, makes it possible to provide the psychological and social support that is essential to the rehabilitation of drug users. AIM: Compare the severity of depressive symptoms in heroin users who are currently receiving MMT to that of heroin users who are not receiving MMT. METHODS: We administered the 13-item version of the Beck Depression Inventory (BDI-13) and a demographic history form to 929 heroin users who had been receiving MMT at nine methadone treatment clinics in three Chinese cities for an average of 9 months and to 238 heroin users who had enrolled in a MMT program at the centers but had not yet begun MMT...
February 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/27670244/psychostimulant-drugs-for-cocaine-dependence
#17
Xavier Castells, Ruth Cunill, Clara Pérez-Mañá, Xavier Vidal, Dolors Capellà
BACKGROUND: Cocaine dependence is a severe disorder for which no medication has been approved. Like opioids for heroin dependence, replacement therapy with psychostimulants could be an effective therapy for treatment. OBJECTIVES: To assess the effects of psychostimulants for cocaine abuse and dependence. Specific outcomes include sustained cocaine abstinence and retention in treatment. We also studied the influence of type of drug and comorbid disorders on psychostimulant efficacy...
September 27, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27664554/variants-of-opioid-system-genes-are-associated-with-non-dependent-opioid-use-and-heroin-dependence
#18
Matthew Randesi, Wim van den Brink, Orna Levran, Peter Blanken, Eduardo R Butelman, Vadim Yuferov, Joel Correa da Rosa, Jurg Ott, Jan M van Ree, Mary Jeanne Kreek
BACKGROUND: Heroin addiction is a chronic, relapsing brain disease. Genetic factors are involved in the development of drug addiction. The aim of this study was to determine whether specific variants in genes of the opioid system are associated with non-dependent opioid use and heroin dependence. METHODS: Genetic information from four subject groups was collected: non-dependent opioid users (NOD) [n=163]; opioid-dependent (OD) patients in methadone maintenance treatment (MMT) [n=143]; opioid-dependent MMT-resistant patients in heroin-assisted treatment (HAT) [n=138]; and healthy controls with no history of opioid use (HC) [n=153]...
September 5, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27641323/learning-and-generalization-from-reward-and-punishment-in-opioid-addiction
#19
Catherine E Myers, Janice Rego, Paul Haber, Kirsten Morley, Kevin D Beck, Lee Hogarth, Ahmed A Moustafa
This study adapts a widely-used acquired equivalence paradigm to investigate how opioid-addicted individuals learn from positive and negative feedback, and how they generalize this learning. The opioid-addicted group consisted of 33 participants with a history of heroin dependency currently in a methadone maintenance program; the control group consisted of 32 healthy participants without a history of drug addiction. All participants performed a novel variant of the acquired equivalence task, where they learned to map some stimuli to correct outcomes in order to obtain reward, and to map other stimuli to correct outcomes in order to avoid punishment; some stimuli were implicitly "equivalent" in the sense of being paired with the same outcome...
January 15, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/27636020/knowledge-and-stigma-regarding-methadone-maintenance-treatment-mmt-among-personnel-of-mmt-and-non-mmt-addiction-facilities-in-israel
#20
Lia Shidlansik, Miriam Adelson, Einat Peles
BACKGROUND: Stigma attached to methadone maintenance treatment (MMT) is very common. OBJECTIVE: To evaluate the presence of stigma and its relation to the extent of knowledge about MMT Methods: We conducted a survey among MMT and non-MMT addiction therapists from different treatment centers in Israel, including MMT clinics (Ministry of Health) and non MMT addiction facilities (Ministry of Social Services), using an anonymous questionnaire about MMT stigma and knowledge...
September 16, 2016: Journal of Addictive Diseases
keyword
keyword
117252
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"