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https://www.readbyqxmd.com/read/29149219/characterization-and-classification-of-lupus-patients-based-on-plasma-thermograms
#1
Nichola C Garbett, Guy N Brock, Jonathan B Chaires, Chongkham S Mekmaysy, Lynn DeLeeuw, Kathy L Sivils, John B Harley, Brad H Rovin, K B Kulasekera, Wael N Jarjour
OBJECTIVE: Plasma thermograms (thermal stability profiles of blood plasma) are being utilized as a new diagnostic approach for clinical assessment. In this study, we investigated the ability of plasma thermograms to classify systemic lupus erythematosus (SLE) patients versus non SLE controls using a sample of 300 SLE and 300 control subjects from the Lupus Family Registry and Repository. Additionally, we evaluated the heterogeneity of thermograms along age, sex, ethnicity, concurrent health conditions and SLE diagnostic criteria...
2017: PloS One
https://www.readbyqxmd.com/read/29149062/polyphenolics-from-albizia-harveyi-exhibit-antioxidant-activities-and-counteract-oxidative-damage-and-ultra-structural-changes-of-cryopreserved-bull-semen
#2
Mansour Sobeh, Soha A Hassan, Mohamed A El Raey, Wael A Khalil, Mahmoud A E Hassan, Michael Wink
Albizia harveyi is a tropical deciduous tree, found across South and Eastern Africa and widely used in traditional medicine. The leaf extract ameliorated the damaging effects of the frozen-thawing process in cryopreserved bull semen. In a dose-dependent pattern, sperm motility, viability, and membrane integrity were improved compared to the untreated control. Furthermore, the extract increased the percentage of viable sperm cells and reduced the percentages of early apoptotic and apoptotic sperm cells as well as the damage in sperm ultra-structure...
November 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29147829/cardiovascular-disease-in-the-literature-a-selection-of-recent-original-research-papers
#3
REVIEW
Wael A AlJaroudi, Fadi G Hage
No abstract text is available yet for this article.
November 16, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29144789/a-comparative-study-of-different-amniotic-membrane-orientations-during-extraocular-muscle-surgery-in-rabbits
#4
Rehab Rashad Kassem, Randa Mohamed Abdel-Moneim El-Mofty, Mustafa Mahmoud Khodeir, Wael Mostafa Hamza
PURPOSE: To histopathologically compare the effect of different orientations of cryopreserved human amniotic membrane (AM) transplant during extraocular muscle surgery in rabbits. METHODS: Fifty-two albino rabbit eyes underwent 4-mm resection of the superior rectus. Eyes were randomly divided into four groups. In Group C (Control group, 16 eyes) the muscle was not wrapped with amniotic membrane. In the three AM groups, cryopreserved AM was wrapped around the muscle, oriented with either its stroma (Group S, 15 eyes) or epithelium (Group E, nine eyes) towards the muscle, or folded on itself with the epithelium externally (Group F, 12 eyes)...
November 16, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29142785/role-of-cord-blood-and-bone-marrow-mesenchymal-stem-cells-in-recent-deep-burn-a-case-control-prospective-study
#5
Wael Abo-Elkheir, Fawzy Hamza, Ahmed M Elmofty, Atef Emam, Magdy Abdl-Moktader, Sameh Elsherefy, Hala Gabr
RATIONALE: Burn injuries represent one of the major worldwide public health problems causing more severe physiological stress than other traumas. Effective treatment of burn injuries is mandatory to prevent the numerous life-threatening complications and possible disabilities. Stem cells, a population of multipotent cells retaining the properties of self-renewal and differentiation, are the main player in tissue regeneration after major trauma. Thus, they are thought to play a key role in wound healing inducing efficient and physiological skin regeneration...
2017: American Journal of Stem Cells
https://www.readbyqxmd.com/read/29140940/rapid-infliximab-infusion-in-children-with-inflammatory-bowel-disease-a-multicenter-north-american-experience
#6
Wael El-Matary, Dana M H Dykes, Laura Bauman, Abdul Elkadri, Matthew W Carroll, Marisa R Izaguirre, Jennifer deBruyn, Charles M Samson, Alisa Muniz Crim, Sabina Ali, Andrew Grossman
BACKGROUND: Infliximab (IFX) infusion may lead to development of anti-IFX antibodies, and subsequent infusion reactions (IRs). The safety of rapid IFX infusion administered over 60 minutes has been under-investigated in children with inflammatory bowel disease. In a multicenter study, the frequency and nature of rapid infusion-associated IRs were examined. METHODS: The medical records of all consecutive children with inflammatory bowel disease receiving rapid IFX infusions between January 2014 and December 2016 were reviewed...
December 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29139036/myocardial-stunning-by-gated-spect-an-old-tool-reinvented-in-a-stunning-turn
#7
EDITORIAL
Wael A AlJaroudi, Fadi G Hage
No abstract text is available yet for this article.
November 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29132762/the-ottawa-hospital-radiologist-activity-reporting-radar-productivity-metric-effects-on-radiologist-productivity
#8
Cynthia Walsh, Jose Aquino, Jean Seely, Ania Kielar, Kawan Rakhra, Carole Dennie, Adnan Sheikh, Michael Kingstone, Adnan Hadziomerovic, Matthew McInnes, Wael Shabana, Chris Bright, Mario Villemaire, Frank J Rybicki
No abstract text is available yet for this article.
November 10, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/29125774/a-one-pot-synthesis-of-highly-functionalized-purines
#9
Renaud Zelli, Waël Zeinyeh, Romain Haudecoeur, Julien Alliot, Benjamin Boucherle, Isabelle Callebaut, Jean-Luc Décout
Highly substituted purines were synthesized in good to high yields through a one-pot straightforward metal-free scalable method, using the Traube synthesis adapted to Vilsmeier-type reagents. From 5-amino-4-chloropyrimidines, new 9-aryl-substituted chloropurines and intermediates for peptide nucleic acid synthesis were prepared. Variant procedures allowing a rapid synthesis of ribonucleosides and 7-benzylpurine from 5-amidino-6-aminopyrimidines are also reported to illustrate the high potential of this versatile toolbox...
November 10, 2017: Organic Letters
https://www.readbyqxmd.com/read/29125456/microbacterium-album-sp-nov-and-microbacterium-deserti-sp-nov-two-halotolerant-actinobacteria-isolated-from-desert-soil
#10
Zi-Wen Yang, Nimaichand Salam, Mohamed Mohany, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Min Xiao, Wael N Hozzein, Wen-Jun Li
Strains SYSU D8007(T) and SYSU D8014(T) were isolated from desert soil collected from Saudi Arabia. The two isolates were Gram-stain-positive, non-motile, aerobic and non-spore-forming. These strains were able to grow at 4-45 °C and in the presence of up to 8 % (w/v) NaCl. Strain SYSU D8007(T) could grow at pH 6.0-10.0, and strain SYSU D8014(T) at pH 5.0-10.0. They shared highest 16S rRNA gene sequence similarities with Microbacterium marinilacus YM11-607(T) and Microbacterium paludicola US15(T). Menaquinones MK-11 and MK-12 were detected as the respiratory quinones...
November 10, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29119374/review-of-cardiovascular-imaging-in-the-journal-of-nuclear-cardiology-2017-part-1-of-2-positron-emission-tomography-computed-tomography-and-magnetic-resonance
#11
Wael A AlJaroudi, Fadi G Hage
Several original articles and editorials have been published in the Journal of Nuclear Cardiology in 2017. It has become a tradition at the beginning of each year to summarize some of these key articles in 2 sister reviews. In this first part one, we will discuss some of the progress made in the field of heart failure (cardio-oncology, myocardial blood flow, viability, dyssynchrony, and risk stratification), inflammation, molecular and hybrid imaging using advancement in positron emission tomography, computed tomography, and magnetic resonance imaging...
November 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29118799/optional-endovascular-therapy-of-dissecting-posterior-cerebral-artery-aneurysm
#12
Mohamed Wael Osman, Krzysztof Kadziolka, Laurent Peirot
BACKGROUND: Posterior cerebral artery aneurysms are uncommon, with an occurrence rate of less than 1% of intracranial aneurysms. They have various shapes, including saccular and fusiform. Dissecting aneurysms may occur in distal posterior cerebral artery and they may affect the whole artery. Endovascular therapy is considered as a safe method of treatment and there are different techniques for endovascular therapy. SUMMARY: Posterior cerebral artery aneurysms are uncommon...
October 2017: Interventional Neurology
https://www.readbyqxmd.com/read/29117070/scleral-self-indentation-during-chandelier-assisted-peripheral-vitrectomy-under-air-for-rhegmatogenous-retinal-detachment-a-retrospective-cohort-study
#13
Wael A Ewais, Ashraf A Nossair, Lamia S Aly
PURPOSE: To evaluate incidence of iatrogenic retinal breaks in eyes for whom self-indentation during chandelier-assisted peripheral vitrectomy under air, for primary retinal detachment, had been performed compared with eyes for whom a nonindentation chandelier-assisted peripheral vitrectomy under air had been performed. METHODS: Retrospective cohort study. One hundred and thirty eyes with primary rhegmatogenous retinal detachment were identified. All the patients had undergone a chandelier-assisted peripheral vitrectomy under air...
November 7, 2017: Retina
https://www.readbyqxmd.com/read/29114945/hyperglycemia-induced-by-chronic-i-p-and-oral-glucose-loading-leads-to-hypertension-through-increased-na-retention-in-proximal-tubule
#14
Selim Fakhruddin, Wael A Alanazi, Hussain N Alhamami, Karen P Briski, Keith E Jackson
Feeding animals glucose, fructose, sucrose, and fat-enriched diets can lead to diet-induced hyperglycemia, severity of which largely depends on type and concentration of nutrients used and length of dietary intervention. As a strategy of dietary intervention, we adopted glucose-enriched diet, drinking water, and intraperitoneal (i.p.) glucose injection at the dose previously determined to be effective to establish a sustained hyperglycemia over a period of 2 weeks. In our current study, we used 4 groups of Sprague Dawley rats: control, glucose-treated, glucose+tempol, and glucose+captopril-treated groups...
November 7, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29108944/optimized-expression-of-the-starmerella-bombicola-lactone-esterase-in-pichia-pastoris-through-temperature-adaptation-codon-optimization-and-co-expression-with-hac1
#15
S De Waele, I Vandenberghe, B Laukens, S Planckaert, S Verweire, I N A Van Bogaert, W Soetaert, B Devreese, K Ciesielska
The Starmerella bombicola lactone esterase (SBLE) is a novel enzyme that, in vivo, catalyzes the intramolecular esterification (lactonization) of acidic sophorolipids in an aqueous environment. In fact, this is an unusual reaction given the unfavorable conditions for dehydration. This characteristic strongly contributes to the potential of SBLE to become a 'green' tool in industrial applications. Indeed, lactonization occurs normally in organic solvents, an application for which microbial lipases are increasingly used as biocatalysts...
November 4, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/29108716/eight-and-counting
#16
EDITORIAL
Waël C Hanna
No abstract text is available yet for this article.
October 20, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29107491/readmission-reoperation-and-complications-total-hip-vs-total-knee-arthroplasty
#17
Jaiben George, Morad Chughtai, Anton Khlopas, Alison K Klika, Wael K Barsoum, Carlos A Higuera, Michael A Mont
BACKGROUND: Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are currently grouped under the same Diagnosis-Related Group (DRG). With the introduction of bundled payments, providers are accountable for all the costs incurred during the episode of care, including the costs of readmissions and management of complications. However, it is unclear whether readmission rates and short-term complications are similar in primary THA and TKA. METHODS: The National Surgical Quality Improvement Project database was queried from 2011 to 2015 to identify 248,150 primary THA/TKA procedures using Current Procedural Terminology codes...
October 5, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29101900/glutaredoxin-2-controls-cardiac-mitochondrial-dynamics-and-energetics-in-mice-and-protects-against-human-cardiac-pathologies
#18
Georges N Kanaan, Bianca Ichim, Lara Gharibeh, Wael Maharsy, David A Patten, Jian Ying Xuan, Arkadiy Reunov, Philip Marshall, John Veinot, Keir Menzies, Mona Nemer, Mary-Ellen Harper
Glutaredoxin 2 (GRX2), a mitochondrial glutathione-dependent oxidoreductase, is central to glutathione homeostasis and mitochondrial redox, which is crucial in highly metabolic tissues like the heart. Previous research showed that absence of Grx2, leads to impaired mitochondrial complex I function, hypertension and cardiac hypertrophy in mice but the impact on mitochondrial structure and function in intact cardiomyocytes and in humans has not been explored. We hypothesized that Grx2 controls cardiac mitochondrial dynamics and function in cellular and mouse models, and that low expression is associated with human cardiac dysfunction...
October 26, 2017: Redox Biology
https://www.readbyqxmd.com/read/29100243/patient-centered-care-and-uterine-fibroids
#19
Erica E Marsh, Shani Chibber, Wael Saad
No abstract text is available yet for this article.
November 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/29099890/the-role-of-synovial-cytokines-in-the-diagnosis-of-periprosthetic-joint-infections-current-concepts
#20
Jared M Newman, Jaiben George, Alison K Klika, Wael K Barsoum, Carlos A Higuera
Periprosthetic joint infection (PJI) is a serious and potentially devastating complication of total joint arthroplasty. Accurate diagnosis of PJI is of utmost importance, but differentiating septic from aseptic failed total joint arthroplasty is extremely challenging, and improper management can lead to significant morbidity. The gold standard for PJI diagnosis is based on standardized laboratory and clinical criteria but relies on preoperative and intraoperative findings, which can be unreliable. Given these limitations, research has focused on new methods for diagnosing PJI...
September 2017: American Journal of Orthopedics
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