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https://www.readbyqxmd.com/read/28335472/detecting-breast-cancer-with-a-dual-modality-device
#1
Kamila Padia, Tania S Douglas, Lydia L Cairncross, Roland V Baasch, Christopher L Vaughan
Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography but adds extra time and cost. The primary aim was to demonstrate that our second-generation Aceso system, which combines full-field digital mammography (FFDM) and automated breast ultrasound (ABUS) in a single platform, is able to produce improved quality images that provide clinically meaningful results...
March 18, 2017: Diagnostics
https://www.readbyqxmd.com/read/28335194/automatic-echographic-detection-of-halloysite-clay-nanotubes-in-a-low-concentration-range
#2
Francesco Conversano, Paola Pisani, Ernesto Casciaro, Marco Di Paola, Stefano Leporatti, Roberto Franchini, Alessandra Quarta, Giuseppe Gigli, Sergio Casciaro
Aim of this work was to investigate the automatic echographic detection of an experimental drug delivery agent, halloysite clay nanotubes (HNTs), by employing an innovative method based on advanced spectral analysis of the corresponding "raw" radiofrequency backscatter signals. Different HNT concentrations in a low range (5.5-66 × 10(10) part/mL, equivalent to 0.25-3.00 mg/mL) were dispersed in custom-designed tissue-mimicking phantoms and imaged through a clinically-available echographic device at a conventional ultrasound diagnostic frequency (10 MHz)...
April 11, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28333625/real-time-nonlocal-means-based-despeckling
#3
Lars H Breivik, Sten Roar Snare, Erik N Steen, Anne H Solberg
In this paper we propose a multiscale nonlocal means based despeckling method for medical ultrasound. The multiscale approach leads to large computational savings and improves despeckling results over single scale iterative approaches. We present two variants of the method. The first, denoted multiscale nonlocal means, yields uniform robust filtering of speckle both in structured and homogeneous regions. The second, denoted unnormalized multiscale nonlocal means, is more conservative in regions of structure assuring minimal disruption of salient image details...
March 22, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28331886/effects-of-line-fiducial-parameters-and-beamforming-on-ultrasound-calibration
#4
Golafsoun Ameri, John S H Baxter, A Jonathan McLeod, Terry M Peters, Elvis C S Chen
Ultrasound (US)-guided interventions are often enhanced via integration with an augmented reality environment, a necessary component of which is US calibration. Calibration requires the segmentation of fiducials, i.e., a phantom, in US images. Fiducial localization error (FLE) can decrease US calibration accuracy, which fundamentally affects the total accuracy of the interventional guidance system. Here, we investigate the effects of US image reconstruction techniques as well as phantom material and geometry on US calibration...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28320658/compressed-sensing-based-synthetic-transmit-aperture-imaging-validation-in-a-convex-array-configuration
#5
Jing Liu, Qiong He, Jianwen Luo
According to the linear acoustic theory, the channel data of a plane wave emitted by a linear array is a linear combination of the full dataset of synthetic transmit aperture (STA). Combining this relationship with compressed sensing (CS), a novel CS based ultrasound beamforming strategy, named compressed sensing based synthetic transmit aperture (CS-STA), was previously proposed to increase the frame rate of ultrasound imaging without sacrificing the image quality for a linear array. In this paper, assuming linear transfer function of pulse-echo ultrasound system, we derived and applied the theory of CS-STA for a slightly curved array and validated CS-STA in a convex array configuration...
March 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28318888/characterization-of-the-lung-parenchyma-using-ultrasound-multiple-scattering
#6
Kaustav Mohanty, John Blackwell, Thomas Egan, Marie Muller
The purpose of the study described here was to showcase the application of ultrasound to quantitative characterization of the micro-architecture of the lung parenchyma to predict the extent of pulmonary edema. The lung parenchyma is a highly complex and diffusive medium for which ultrasound techniques have remained qualitative. The approach presented here is based on ultrasound multiple scattering and exploits the complexity of ultrasound propagation in the lung structure. The experimental setup consisted of a linear transducer array with an 8-MHz central frequency placed in contact with the lung surface...
March 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28318887/multi-focus-beamforming-for-thermal-strain-imaging-using-a-single-ultrasound-linear-array-transducer
#7
Man M Nguyen, Xuan Ding, Steven A Leers, Kang Kim
Ultrasound-induced thermal strain imaging (TSI) has been used successfully to identify lipid- and water-based tissues in atherosclerotic plaques in some research settings. However, TSI faces several challenges to be realized in clinics. These challenges include motion artifacts and displacement tracking accuracy, as well as limited heating capability, which contributes to low thermal strain signal-to-noise ratio, and a limited field of view. Our goal was to address the challenge in heating tissue in TSI. Current TSI systems use separate heating and imaging transducers, which require physical alignment of the heating and imaging beams and result in a bulky setup that limits in vivo operation...
March 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28301597/boiling-histotripsy-lesion-characterization-on-a-clinical-magnetic-resonance-imaging-guided-high-intensity-focused-ultrasound-system
#8
Avinash Eranki, Navid Farr, Ari Partanen, Karun V Sharma, Hong Chen, Christopher T Rossi, Satya V V N Kothapalli, Matthew Oetgen, AeRang Kim, Ayele H Negussie, David Woods, Bradford J Wood, Peter C W Kim, Pavel S Yarmolenko
PURPOSE: High intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that can thermally ablate tumors. Boiling histotripsy (BH) is a HIFU approach that can emulsify tissue in a few milliseconds. Lesion volume and temperature effects for different BH sonication parameters are currently not well characterized. In this work, lesion volume, temperature distribution, and area of lethal thermal dose were characterized for varying BH sonication parameters in tissue-mimicking phantoms (TMP) and demonstrated in ex vivo tissues...
2017: PloS One
https://www.readbyqxmd.com/read/28299710/high-resolution-microultrasound-%C3%AE-us-investigation-of-the-gastrointestinal-gi-tract
#9
Thineskrishna Anbarasan, Christine E M Démoré, Holly Lay, Mohammed R S Sunoqrot, Romans Poltarjonoks, Sandy Cochran, Benjamin F Cox
High resolution, microultrasound (μUS) scanning of the gastrointestinal (GI) tract has potential as an important transmural imaging modality to aid in diagnosis. Operating at higher frequencies than conventional clinical ultrasound instruments, μUS is capable of providing scanned images of the GI tract with higher resolution. To investigate the use of μUS for this application, a phantom which is cost effective, within ethical guidelines and, most importantly, similar in histology to the human GI tract is necessary...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28297305/comparison-of-the-low-contrast-detectability-of-two-ultrasound-systems-using-a-grayscale-phantom
#10
Robert Lorentsson, Nasser Hosseini, Jan-Olof Johansson, Wiebke Rosenberg, Benny Stenborg, Lars Gunnar Månsson, Magnus Båth
The purpose of the present study was to use a commercially available grayscale phantom to compare two ultrasound systems regarding their ability to reproduce clinically relevant low-contrast objects at different sizes and depths, taking into account human observer variability and other methodological issues related to observer performance studies. One high-end and one general ultrasound scanner from the same manufacturer using the same probe were included. The study was intended to simulate the clinical situation where small low-contrast objects are embedded in relatively homogeneous organs...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28295403/toward-a-3d-transrectal-ultrasound-system-for-verification-of-needle-placement-during-high-dose-rate-interstitial-gynecologic-brachytherapy
#11
Jessica Robin Rodgers, Kathleen Surry, Eric Leung, David D'Souza, Aaron Fenster
PURPOSE: Treatment for gynecologic cancers, such as cervical, recurrent endometrial, and vaginal malignancies, commonly includes external-beam radiation and brachytherapy. In high-dose-rate (HDR) interstitial gynecologic brachytherapy, radiation treatment is delivered via hollow needles that are typically inserted through a template on the perineum with a cylinder placed in the vagina for stability. Despite the need for precise needle placement to minimize complications and provide optimal treatment, there is no standard intra-operative image-guidance for this procedure...
March 15, 2017: Medical Physics
https://www.readbyqxmd.com/read/28295027/improved-shear-wave-motion-detection-using-coded-excitation-for-transient-elastography
#12
Xiao-Nian He, Xian-Fen Diao, Hao-Ming Lin, Xin-Yu Zhang, Yuan-Yuan Shen, Si-Ping Chen, Zheng-Di Qin, Xin Chen
Transient elastography (TE) is well adapted for use in studying liver elasticity. However, because the shear wave motion signal is extracted from the ultrasound signal, the weak ultrasound signal can significantly deteriorate the shear wave motion tracking process and make it challenging to detect the shear wave motion in a severe noise environment, such as within deep tissues and within obese patients. This paper, therefore, investigated the feasibility of implementing coded excitation in TE for shear wave detection, with the hypothesis that coded ultrasound signals can provide robustness to weak ultrasound signals compared with traditional short pulse...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28287955/accurate-3-d-profile-extraction-of-skull-bone-using-an-ultrasound-matrix-array
#13
Mehdi Hajian, Robert Gaspar, Roman Maev
The present study investigates the feasibility, accuracy, and precision of 3-D profile extraction of the human skull bone using a custom-designed ultrasound matrix transducer in Pulse-Echo. Due to the attenuative scattering properties of the skull, the backscattered echoes from the inner surface of the skull are severely degraded, attenuated, and at some points overlapped. Furthermore, the speed of sound (SOS) in the skull varies significantly in different zones and also from case to case; if considered constant, it introduces significant error to the profile measurement...
March 8, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28287747/assessment-of-gold-nano-particle-mediated-enhanced-hyperthermia-using-mr-guided-high-intensity-focused-ultrasound-ablation-procedure
#14
Surendra Balaji Devarakonda, Matthew R Myers, Matthew Lanier, Charles Dumoulin, Rupak Kumar Banerjee
High-intensity focused ultrasound (HIFU) has gained increasing popularity as a non-invasive therapeutic procedure to treat solid tumors. However, collateral damage due to the use of high acoustic powers during HIFU procedures remains a challenge. The objective of this study is to assess the utility of using gold nano-particles (gNPs) during HIFU procedures to locally enhance heating at low powers, thereby reducing the likelihood of collateral damage. Phantoms containing tissue-mimicking material (TMM) and physiologically relevant concentrations (0%, 0...
March 13, 2017: Nano Letters
https://www.readbyqxmd.com/read/28285339/acoustic-window-planning-for-ultrasound-acquisition
#15
Rüdiger Göbl, Salvatore Virga, Julia Rackerseder, Benjamin Frisch, Nassir Navab, Christoph Hennersperger
Autonomous robotic ultrasound has recently gained considerable interest, especially for collaborative applications. Existing methods for acquisition trajectory planning are solely based on geometrical considerations, such as the pose of the transducer with respect to the patient surface. PURPOSE: This work aims at establishing acoustic window planning to enable autonomous ultrasound acquisitions of anatomies with restricted acoustic windows, such as the liver or the heart. METHODS: We propose a fully automatic approach for the planning of acquisition trajectories, which only requires information about the target region as well as existing tomographic imaging data, such as X-ray computed tomography...
March 11, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28282862/an-assessment-of-iterative-reconstruction-methods-for-sparse-ultrasound-imaging
#16
Solivan A Valente, Marcelo V W Zibetti, Daniel R Pipa, Joaquim M Maia, Fabio K Schneider
Ultrasonic image reconstruction using inverse problems has recently appeared as an alternative to enhance ultrasound imaging over beamforming methods. This approach depends on the accuracy of the acquisition model used to represent transducers, reflectivity, and medium physics. Iterative methods, well known in general sparse signal reconstruction, are also suited for imaging. In this paper, a discrete acquisition model is assessed by solving a linear system of equations by an ℓ 1 -regularized least-squares minimization, where the solution sparsity may be adjusted as desired...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28276684/ultrasound-induced-magnetic-imaging-of-tumors-targeted-by-biofunctional-magnetic-nanoparticles
#17
Kai-Wen Huang, Jen-Jie Chieh, Chih-Kuang Yeh, Shu-Hsien Liao, Yi-Yan Lee, Pei-Yi Hsiao, Wen-Chun Wei, Hong-Chang Yang, Herng-Er Horng
Biofunctional magnetic nanoparticles (MNPs) have been widely applied in biomedical engineering. MNPs are used as a contrast medium in magnetic imaging. Current methods of magnetic imaging, such as magnetic particle imaging and magnetic relaxometry, use small amounts of MNPs at target points far from the surface of the patient's body; these methods always consume considerable power to produce magnetic fields of high uniformity or gradient excitations. Some drawbacks, such as a limited imaging region, imaging system shielding, and complex algorithms based on assumptions of MNP properties or environmental factors, also limit the application of MNP methods in clinics...
March 9, 2017: ACS Nano
https://www.readbyqxmd.com/read/28275423/in-vivo-imaging-of-ocular-blood-flow-using-high-speed-ultrasound
#18
Jeffrey A Ketterling, Raksha Urs, Ronald H Silverman
Clinical ophthalmic ultrasound is currently performed with mechanically scanned, single-element probes, but these are unable to provide useful information about blood flow with Doppler techniques. Linear arrays are well-suited for the detection of blood flow, but commercial systems generally exceed FDA ophthalmic safety limits. A high-speed plane-wave ultrasound approach with an 18-MHz linear array was utilized to characterize blood flow in the orbit and choroid. Acoustic intensity was measured and the plane-wave mode was within FDA limits...
September 2016: IEEE International Ultrasonics Symposium: [proceedings]
https://www.readbyqxmd.com/read/28269437/artsens%C3%A2-mobile-a-portable-image-free-platform-for-automated-evaluation-of-vascular-stiffness
#19
Malay Ilesh Shah, Jayaraj Joseph, T Aryasree, Mohanasankar Sivaprakasam
Vascular stiffness is a key physiological marker significant in screening and early diagnosis of vascular disease. However, state of art techniques for vascular stiffness evaluation are not suited for field deployment. We present ARTSENS® Mobile, a portable, image-free ultrasound technology platform for automated evaluation of carotid artery stiffness, amenable for field deployment. The technology utilises a single element ultrasound transducer operated in pulse echo modality to investigate arterial wall dynamics, assisted by intelligent algorithms for wall identification and motion tracking to completely automate the measurement...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269071/pre-clinical-investigations-of-multi-path-propagation-in-transcranial-doppler-ultrasound-flow-phantom
#20
Alexander J Weir, Cheng-Xiang Wang, Stuart Parks
There are various practical situations in medical applications when pre-clinical investigations must be performed using a simulation environment or test bench prior to human studies. One example is the analysis of propagation channels in Transcanial Doppler (TCD) ultrasound (US), a signal processing challenge requiring the analysis of data from US waves scattered in three dimensions (3D). When examining the effects of scatterers in such channels, it is common to use a data acquisition test bench and a Doppler flow phantom...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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