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nanomaterial and biofilm

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https://www.readbyqxmd.com/read/29757931/in-vitro-human-microbiota-response-to-exposure-to-silver-nanoparticles-biosynthesized-with-mushroom-extract
#1
Emanuel Vamanu, Mihaela Ene, Bogdan Biță, Cristina Ionescu, Liviu Crăciun, Ionela Sârbu
The ability to orally administer silver nanoparticles (AgNPs) in enteric capsules implies a direct interaction with the colon microbiota. The in vitro effect provides a portrayal of the functional properties under in vivo conditions. The purpose of this study was to describe a green AgNP synthesis process, using aqueous extract from Lactarius piperatus mushroom, and to characterize the nanomaterial. We determined its antimicrobial and antioxidant effects in vitro in the microbiota of healthy individuals via the GIS1 system-a colon transit simulator...
May 14, 2018: Nutrients
https://www.readbyqxmd.com/read/29755737/inactivation-of-pure-bacterial-biofilms-by-impaction-of-aerosolized-consumer-products-containing-nanoparticulate-metals
#2
Jennifer Therkorn, Leonardo Calderon, Benton Cartledge, Nirmala Thomas, Brian Majestic, Gediminas Mainelis
The ability of nanotechnology-enabled consumer sprays to inactivate bacteria has direct health implications. This research investigated the ability of six nanosilver-based consumer sprays to inactivate bacteria. We determined the minimal inhibitory concentrations (MICs) of the products by an agar dilution method, collected particles released from sprays onto bacterial films using impactors, and determined metal concentrations in the products using ICPMS. Also, the size of silver nanoparticles in the products' suspensions was determined using single particle (sp)ICPMS...
February 1, 2018: Environmental Science. Nano
https://www.readbyqxmd.com/read/29614721/antimicrobial-activity-of-al%C3%A2-o%C3%A2-cuo-fe%C3%A2-o%C3%A2-and-zno-nanoparticles-in-scope-of-their-further-application-in-cement-based-building-materials
#3
Pawel Sikora, Adrian Augustyniak, Krzysztof Cendrowski, Paweł Nawrotek, Ewa Mijowska
Nanoparticles were proposed as antibacterial cement admixtures for the production of cement-based composites. Nevertheless, the standards for evaluation of such admixtures still do not indicate which model organisms to use, particularly in regard to the further application of material. Apart from the known toxicity of nanomaterials, in the case of cement-based composites there are limitations associated with the mixing and dispersion of nanomaterials. Therefore, four nanooxides (Al₂O₃, CuO, Fe₃O₄, and ZnO) and seven microorganisms were tested to initially evaluate the applicability of nanooxides in relation to their further use in cement-based composites...
March 31, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29573683/inhibition-of-biofilm-growth-on-polymer-mwcnts-composites-and-metal-surfaces
#4
Hengye Jing, Endalkachew Sahle-Demessie, George A Sorial
There is an increased interest in incorporating multi-wall carbon nanotubes (MWCNTs) into polymer matrices to control the adhesion of bacteria to surfaces and the subsequent formation of biofilm growth on the surface of water pipes, food packages, and medical devices. Microbial interactions with carbon nanotube-polymer composites in the environment are not well understood. The growth of Pseudomonas fluorescens (gram-negative) and Mycobacterium smegmatis (gram-positive) biofilms on copper, polyethylene (PE), polyvinyl chloride, and stainless steel was compared with growth on MWCNT-PE composites in order to gain insight into the effect of the surface properties of nanomaterials on the attachment and proliferation of microorganism which could result in the engineering of better, non-fouling materials...
March 21, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29539262/synthesis-self-assembly-and-biomedical-applications-of-antimicrobial-peptide-polymer-conjugates
#5
Hui Sun, Yuanxiu Hong, Yuejing Xi, Yijie Zou, Jingyi Gao, Jianzhong Du
Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR) which has been increasing globally to alarming levels. Conjugation of AMPs into functional polymers not only preserves excellent antimicrobial activities but reduces the toxicity and offers more functionalities, which brings new insight towards developing multifunctional biomedical materials such as hydrogels, polymer vesicles, polymer micelles, etc...
March 14, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29533854/self-assembly-of-bacterial-amyloid-protein-nanomaterials-on-solid-surfaces
#6
Tugce Onur, Esra Yuca, Tolga Tarkan Olmez, Urartu Ozgur Safak Seker
HYPOTHESIS: Amyloid-forming biofilm proteins of Escherichia coli, namely CsgA and CsgB, can form self-assembled nanofibers on solid surfaces. These proteins can be programmed to form bio-nanomaterials for functional applications. EXPERIMENTS: In this study, the assembly of the CsgA and CsgB protein on solid surfaces was investigated in real time using a quartz crystal microbalance instrument with dissipation monitoring. The assembly kinetics of the CsgA and CsgB proteins in various settings on solid surfaces were investigated...
March 7, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29510358/swift-fabrication-of-ag-nanostructures-using-a-colloidal-solution-of-holostemma-ada-kodien-apocynaceae-antibiofilm-potential-insecticidal-activity-against-mosquitoes-and-non-target-impact-on-water-bugs
#7
Sami A Alyahya, Marimuthu Govindarajan, Naiyf S Alharbi, Shine Kadaikunnan, Jamal M Khaled, Ramzi A Mothana, Mohammed N Al-Anbr, Baskaralingam Vaseeharan, Ramachandran Ishwarya, Mariappan Yazhiniprabha, Giovanni Benelli
Recent research in entomology and parasitology focused on the efficacy of green fabricated nanomaterials as novel insecticides. In this study, we synthesized poly-dispersed and stable silver nanoparticles (AgNPs) using the leaf extract of Holostemma ada-kodien. The nanostructures were characterized by ultraviolet-visible spectroscopy, Fourier-transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray, and X-ray diffraction analysis. The efficacy of H...
April 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29473883/emerging-nanomedicine-therapies-to-counter-the-rise-of-methicillin-resistant-staphylococcus-aureus
#8
REVIEW
Alan Hibbitts, Cian O'Leary
In a recent report, the World Health Organisation (WHO) classified antibiotic resistance as one of the greatest threats to global health, food security, and development. Methicillin-resistant Staphylococcus aureus (MRSA) remains at the core of this threat, with persistent and resilient strains detectable in up to 90% of S. aureus infections. Unfortunately, there is a lack of novel antibiotics reaching the clinic to address the significant morbidity and mortality that MRSA is responsible for. Recently, nanomedicine strategies have emerged as a promising therapy to combat the rise of MRSA...
February 23, 2018: Materials
https://www.readbyqxmd.com/read/29445231/impact-of-nanoparticles-on-the-bacillus-subtilis-3610-competence
#9
Elise Eymard-Vernain, Sylvie Luche, Thierry Rabilloud, Cécile Lelong
Due to the physicochemical properties of nanoparticles, the use of nanomaterials increases every year in industrial and medical processes. At the same time, the increasing number of bacteria becoming resistant to many antibiotics, mostly by a horizontal gene transfer process, is a major public health concern. We herein report, for the first time, the role of nanoparticles in the physiological induction of horizontal gene transfer in bacteria. Besides the most well-known impacts of nanoparticles on bacteria, i...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29410321/soft-adhesive-alpha-tocopherol-phosphate-planar-bilayers-that-control-oral-biofilm-growth-through-a-substantive-antimicrobial-effect
#10
Robert A Harper, Mais M Saleh, Guy Carpenter, Vincenzo Abbate, Gordon Proctor, Richard D Harvey, Robert J Gambogi, Anthony Geonnotti, Robert Hider, Stuart A Jones
'Soft' nanomaterials have the potential to produce substantive antibiofilm effects. The aim of this study was to understand the oral antimicrobial activity of soft nanomaterials generated from alpha-tocopherol (α-T) and alpha-tocopherol phosphate (α-TP). (+) α-TP formed planar bilayer islands (175 ± 21 nm, -14.9 ± 3.5 mV) in a Trizma® buffer, whereas (+) α-T formed spherical liposomes (563 ± 1 nm, -10.5 ± 0.2 mV). The (+) α-TP bilayers displayed superior Streptococcus oralis biofilm growth retardation, a more substantive action, generated a superior adsorption to hydroxyapatite and showed an enhanced inhibition of multi-species bacterial saliva biofilm growth (38 ± 7μm vs 58 ± 18 μm, P ˂ 0...
February 2, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29343729/drug-self-assembly-for-synthesis-of-highly-loaded-antimicrobial-drug-silica-particles
#11
Cameron A Stewart, Yoav Finer, Benjamin D Hatton
Antimicrobial drug release from biomaterials for orthopedic repair and dental restorations can prevent biofilm growth and caries formation. Carriers for drug incorporation would benefit from long-term drug storage, controlled release, and structural stability. Mesoporous silica, synthesized through a co-assembly of silica and surfactant template, is an ideal drug encapsulation scaffold that maintains structural integrity upon release. However, conventional loading of drug within meso-silica pores via concentration-gradient diffusion limits the overall payload, concentration uniformity, and drug release control...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29233187/graphene-based-dental-adhesive-with-anti-biofilm-activity
#12
Agnese Bregnocchi, Elena Zanni, Daniela Uccelletti, Fabrizio Marra, Domenico Cavallini, Francesca De Angelis, Giovanni De Bellis, Maurizio Bossù, Gaetano Ierardo, Antonella Polimeni, Maria Sabrina Sarto
BACKGROUND: Secondary caries are considered the main cause of dental restoration failure. In this context, anti-biofilm and bactericidal properties are desired in dental materials against pathogens such as Streptococcus mutans. To this purpose, graphene based materials can be used as fillers of polymer dental adhesives. In this work, we investigated the possibility to use as filler of dental adhesives, graphene nanoplatelets (GNP), a non toxic hydrophobic nanomaterial with antimicrobial and anti-biofilm properties...
December 12, 2017: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/29219055/the-role-of-nanoparticles-in-the-inhibition-of-multidrug-resistant-bacteria-and-biofilms
#13
Manaf AlMatar, Essam A Makky, Isil Var, Fatih Koksal
BACKGROUND: Until recently, one of the main reasons for mortality has been infectious diseases, and bacteria that are drug-resistant have emerged as a result of the wide application, as well as the misuse, of antibacterial medications. Having multidrug-resistance, bacteria present a great problem for the efficient management of bacterial infections and this challenge has resulted in the creation of other means of dealing with bacterial diseases. Of late, metallic nanoparticles (NPs), employed as antibacterial agents, have the potential for use against resistance to bacterial drugs...
December 7, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/29216517/go-agcl-ag-nanocomposites-with-enhanced-visible-light-driven-catalytic-properties-for-antibacterial-and-biofilm-disrupting-applications
#14
Xinhuan Wang, Qiusen Han, Ning Yu, Tian Wang, Chen Wang, Rong Yang
Nanomaterials with visible light-driven photocatalytic activity have attracted much attention due to their excellent abilities in degradation of various organic pollutants as well as inactivating bacteria. Herein, graphene oxide (GO) enwrapped silver chloride/silver (AgCl/Ag) nanocomposites with high visible light absorption were designed and fabricated as efficient antibacterial agents. AgCl NPs were synthesized in the presence of GO first and Ag NPs were coated on AgCl surface by heat reduction to form GO-AgCl/Ag nanocomposites...
February 1, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29199549/characterization-of-moderately-halotolerant-selenate-and-tellurite-reducing-bacteria-isolated-from-brackish-areas-in-osaka
#15
Satoshi Soda, Wenbo Ma, Masashi Kuroda, Hiroshi Nishikawa, Yuanyuan Zhang, Michihiko Ike
Moderately halotolerant selenate- and tellurite-reducing bacteria were characterized for wastewater treatment applications. A selenate-reducing strain 9a was isolated from the biofilm of a leachate treatment plant at a sea-based waste disposal site. A tellurite-reducing strain Taa was isolated from an enrichment culture derived from brackish sediment. Both bacterial strains were Shewanella species. Strain 9a could anaerobically remove 45-70% of 1.0 mM selenate and selenite from water containing up to 3% NaCl within 4 days, while strain Taa could anaerobically and aerobically remove 70-90% of 0...
January 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29184409/nanomaterials-for-alternative-antibacterial-therapy
#16
REVIEW
Hassan A Hemeg
Despite an array of cogent antibiotics, bacterial infections, notably those produced by nosocomial pathogens, still remain a leading factor of morbidity and mortality around the globe. They target the severely ill, hospitalized and immunocompromised patients with incapacitated immune system, who are prone to infections. The choice of antimicrobial therapy is largely empirical and not devoid of toxicity, hypersensitivity, teratogenicity and/or mutagenicity. The emergence of multidrug-resistant bacteria further intensifies the clinical predicament as it directly impacts public health due to diminished potency of current antibiotics...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29164404/size-selectivity-in-antibiofilm-activity-of-3-diphenylphosphino-propanoic-acid-coated-gold-nanomaterials-against-gram-positive-staphylococcus-aureus-and-streptococcus-mutans
#17
Dania Ahmed, Ayaz Anwar, Anum Khalid Khan, Ayaz Ahmed, Muhammad Raza Shah, Naveed Ahmed Khan
Biofilm formation by pathogenic bacteria is one of the major threats in hospital related infections, hence inhibiting and eradicating biofilms has become a primary target for developing new anti-infection approaches. The present study was aimed to develop novel antibiofilm agents against two Gram-positive bacteria; Staphylococcus aureus (ATCC 43300) and Streptococcus mutans (ATCC 25175) using gold nanomaterials conjugated with 3-(diphenylphosphino)propionic acid (Au-LPa). Gold nanomaterials with different sizes as 2-3 nm small and 9-90 nm (50 nm average size) large were stabilized by LPa via different chemical synthetic strategies...
November 21, 2017: AMB Express
https://www.readbyqxmd.com/read/29143262/influences-of-graphene-oxide-on-biofilm-formation-of-gram-negative-and-gram-positive-bacteria
#18
Chao Song, Chun-Miao Yang, Xue-Fei Sun, Peng-Fei Xia, Jing Qin, Bei-Bei Guo, Shu-Guang Wang
In this study, we evaluated the influences of graphene oxide (GO) on biofilm formation. Escherichia coli MG1655 and Bacillus subtilis 168 were used as models for Gram-negative and Gram-positive bacteria. The growth profiles and viability assays indicated that GO exhibited a high antibacterial activity, of which the negative effects on bacteria growth raised with the increasing GO concentration. The antibacterial activity of GO was mainly attributed to the membrane stress and ROS-independent oxidative stress...
January 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29102240/emerging-biomedical-applications-of-enzyme-like-catalytic-nanomaterials
#19
REVIEW
David P Cormode, Lizeng Gao, Hyun Koo
Nanomaterials have been developed for many biomedical applications, including medical imaging, drug delivery, and antimicrobial coatings. Intriguingly, nanoparticles can display 'enzyme-like' activity and have been explored as alternatives to natural enzymes in several industrial and energy-related applications. Recently, these catalytic nanomaterials with enzyme-mimetic properties have found new biomedical applications, from biofilm disruption to protection against neurodegeneration and tumor prevention. In this review we focus on recent in vivo studies demonstrating potential therapeutic uses of catalytic nanomaterials...
January 2018: Trends in Biotechnology
https://www.readbyqxmd.com/read/29098517/influence-of-aptamer-targeted-antibiofilm-agents-for-treatment-of-pseudomonas-aeruginosa-biofilms
#20
Sheng Wang, Biyao Mao, Mingxi Wu, Jingjing Liang, Le Deng
Biofilms are bacterial communities consisting of numerous extracellular polymeric substances. Infections caused by biofilm-forming bacteria are considered to be a major threat to health security and so novel approaches to control biofilm are of importance. Aptamers are single-strand nucleic acid molecules that have high selectivity to their targets. Single-walled carbon nanotubes (SWNTs) are common nanomaterials and have been shown to be toxic to bacterial biofilms. The aim of this study was to test whether an aptamer could play a role as targeting agents to enhance the efficiency of anti-biofilm agents...
November 2, 2017: Antonie Van Leeuwenhoek
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